WO2001064713A3 - Mammalian interleukin-10 (il-10) receptor variants - Google Patents

Mammalian interleukin-10 (il-10) receptor variants Download PDF

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Publication number
WO2001064713A3
WO2001064713A3 PCT/EP2001/002296 EP0102296W WO0164713A3 WO 2001064713 A3 WO2001064713 A3 WO 2001064713A3 EP 0102296 W EP0102296 W EP 0102296W WO 0164713 A3 WO0164713 A3 WO 0164713A3
Authority
WO
WIPO (PCT)
Prior art keywords
receptor variants
mammalian interleukin
therapeutic
diagnostic
reagents
Prior art date
Application number
PCT/EP2001/002296
Other languages
French (fr)
Other versions
WO2001064713A2 (en
Inventor
Christoph Gasche
Schaker M Zakeri
Walter Reinisch
Original Assignee
Christoph Gasche
Schaker M Zakeri
Walter Reinisch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Christoph Gasche, Schaker M Zakeri, Walter Reinisch filed Critical Christoph Gasche
Priority to AU2001256174A priority Critical patent/AU2001256174A1/en
Publication of WO2001064713A2 publication Critical patent/WO2001064713A2/en
Publication of WO2001064713A3 publication Critical patent/WO2001064713A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Amino acid sequence and nucleic acid encoding variants of the IL-10 receptors, including polymorphisms. Uses of the receptor gene and polypeptides are disclosed, including means for screening for agonists and antagonists of the receptor ligands, for producing diagnostic or therapeutic reagents, and for producing antibodies. Therapeutic or diagnostic reagents and kits are also provided.
PCT/EP2001/002296 2000-03-01 2001-03-01 Mammalian interleukin-10 (il-10) receptor variants WO2001064713A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001256174A AU2001256174A1 (en) 2000-03-01 2001-03-01 Mammalian interleukin-10 (il-10) receptor variants

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18612500P 2000-03-01 2000-03-01
US60/186,125 2000-03-01

Publications (2)

Publication Number Publication Date
WO2001064713A2 WO2001064713A2 (en) 2001-09-07
WO2001064713A3 true WO2001064713A3 (en) 2002-06-27

Family

ID=22683741

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/002296 WO2001064713A2 (en) 2000-03-01 2001-03-01 Mammalian interleukin-10 (il-10) receptor variants

Country Status (2)

Country Link
AU (1) AU2001256174A1 (en)
WO (1) WO2001064713A2 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945543B2 (en) 2005-06-10 2015-02-03 Chugai Seiyaku Kabushiki Kaisha Stabilizer for protein preparation comprising meglumine and use thereof
US9241994B2 (en) 2005-06-10 2016-01-26 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical compositions containing sc(Fv)2
US9493569B2 (en) 2005-03-31 2016-11-15 Chugai Seiyaku Kabushiki Kaisha Structural isomers of sc(Fv)2

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7696325B2 (en) 1999-03-10 2010-04-13 Chugai Seiyaku Kabushiki Kaisha Polypeptide inducing apoptosis
DE60133479T2 (en) 2000-10-20 2009-04-16 Chugai Seiyaku K.K. MODIFIED TPO AGONISTS ANTIBODIES
JP2004279086A (en) 2003-03-13 2004-10-07 Konica Minolta Holdings Inc Radiation image conversion panel and method for manufacturing it
JP4739954B2 (en) * 2003-03-13 2011-08-03 中外製薬株式会社 Ligands with agonist activity for mutant receptors
ES2592271T3 (en) 2005-03-31 2016-11-29 Chugai Seiyaku Kabushiki Kaisha Polypeptide production methods by regulating the association of polypeptides
EP4218801A3 (en) 2006-03-31 2023-08-23 Chugai Seiyaku Kabushiki Kaisha Antibody modification method for purifying bispecific antibody
US20160090637A1 (en) * 2013-05-14 2016-03-31 Wei Chen Pharmacogenomic Biomarkers for B Cell Malignancies and Methods of Use Thereof
AU2014325063B2 (en) 2013-09-27 2019-10-31 Chugai Seiyaku Kabushiki Kaisha Method for producing polypeptide heteromultimer
EP3398965A4 (en) 2015-12-28 2019-09-18 Chugai Seiyaku Kabushiki Kaisha Method for promoting efficiency of purification of fc region-containing polypeptide

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716804A (en) * 1995-04-19 1998-02-10 Schering Corporation Mammalian interleukin-10 (IL-10) super-activating receptors; and variants
US5863796A (en) * 1992-12-10 1999-01-26 Schering Corporation Antibodies which specifically bind mammalian receptors for interleukin-10 (IL-10)

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863796A (en) * 1992-12-10 1999-01-26 Schering Corporation Antibodies which specifically bind mammalian receptors for interleukin-10 (IL-10)
US5985828A (en) * 1992-12-10 1999-11-16 Schering Corporation Mammalian receptors for interleukin-10 (IL-10)
US5716804A (en) * 1995-04-19 1998-02-10 Schering Corporation Mammalian interleukin-10 (IL-10) super-activating receptors; and variants

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9493569B2 (en) 2005-03-31 2016-11-15 Chugai Seiyaku Kabushiki Kaisha Structural isomers of sc(Fv)2
US8945543B2 (en) 2005-06-10 2015-02-03 Chugai Seiyaku Kabushiki Kaisha Stabilizer for protein preparation comprising meglumine and use thereof
US9241994B2 (en) 2005-06-10 2016-01-26 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical compositions containing sc(Fv)2

Also Published As

Publication number Publication date
AU2001256174A1 (en) 2001-09-12
WO2001064713A2 (en) 2001-09-07

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