WO2001060864A3 - Human ion channels - Google Patents

Human ion channels Download PDF

Info

Publication number
WO2001060864A3
WO2001060864A3 PCT/US2001/004644 US0104644W WO0160864A3 WO 2001060864 A3 WO2001060864 A3 WO 2001060864A3 US 0104644 W US0104644 W US 0104644W WO 0160864 A3 WO0160864 A3 WO 0160864A3
Authority
WO
WIPO (PCT)
Prior art keywords
ion channels
provides
human ion
ion channel
methods
Prior art date
Application number
PCT/US2001/004644
Other languages
French (fr)
Other versions
WO2001060864A2 (en
Inventor
Steven L Roberds
Alla M Karnovsky
Cara L Ruble
Original Assignee
Upjohn Co
Steven L Roberds
Alla M Karnovsky
Cara L Ruble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co, Steven L Roberds, Alla M Karnovsky, Cara L Ruble filed Critical Upjohn Co
Priority to AU2001238221A priority Critical patent/AU2001238221A1/en
Priority to EP01910631A priority patent/EP1257580A2/en
Publication of WO2001060864A2 publication Critical patent/WO2001060864A2/en
Publication of WO2001060864A3 publication Critical patent/WO2001060864A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The present invention provides novel ion channel polypeptides and polynucleotides which identify and encode them. In addition, the invention provides expression vectors, host cells and methods for their production. The invention also provides methods for the identification of ion channel agonists/antagonists, useful for the treatment of human diseases and conditions.
PCT/US2001/004644 2000-02-14 2001-02-14 Human ion channels WO2001060864A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001238221A AU2001238221A1 (en) 2000-02-14 2001-02-14 Human ion channels
EP01910631A EP1257580A2 (en) 2000-02-14 2001-02-14 Human ion channels

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18232500P 2000-02-14 2000-02-14
US60/182,325 2000-02-14

Publications (2)

Publication Number Publication Date
WO2001060864A2 WO2001060864A2 (en) 2001-08-23
WO2001060864A3 true WO2001060864A3 (en) 2002-03-28

Family

ID=22667960

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/004644 WO2001060864A2 (en) 2000-02-14 2001-02-14 Human ion channels

Country Status (3)

Country Link
EP (1) EP1257580A2 (en)
AU (1) AU2001238221A1 (en)
WO (1) WO2001060864A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599709A (en) * 1989-09-28 1997-02-04 The Salk Institute For Biological Studies Recombinant DNA encoding neuronal α-bungarotoxin-binding proteins
EP0884386A1 (en) * 1997-05-30 1998-12-16 Synthelabo Sodium channel receptor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599709A (en) * 1989-09-28 1997-02-04 The Salk Institute For Biological Studies Recombinant DNA encoding neuronal α-bungarotoxin-binding proteins
EP0884386A1 (en) * 1997-05-30 1998-12-16 Synthelabo Sodium channel receptor

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE GENEMBL 18 November 1999 (1999-11-18), BIRREN, B. ET AL.: "Homo sapiens clone RP11-351D9, WORKING DRAFT SEQUENCE", XP002172576 *
DATABASE GENEMBL 31 March 1999 (1999-03-31), MAHAIRAS,G.G. ET AL.: "HS_5052_A2_D05_T7A RPCI-11 Human Male BAC Library Homo sapiens genomic clone Plate=628 Col=10 Row=G, genomic survey sequence", XP002172577 *

Also Published As

Publication number Publication date
WO2001060864A2 (en) 2001-08-23
AU2001238221A1 (en) 2001-08-27
EP1257580A2 (en) 2002-11-20

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