WO2001049847A3 - 26904, 38911, and 39404, seven-transmembrane proteins/g-protein coupled receptors - Google Patents

26904, 38911, and 39404, seven-transmembrane proteins/g-protein coupled receptors Download PDF

Info

Publication number
WO2001049847A3
WO2001049847A3 PCT/US2000/035309 US0035309W WO0149847A3 WO 2001049847 A3 WO2001049847 A3 WO 2001049847A3 US 0035309 W US0035309 W US 0035309W WO 0149847 A3 WO0149847 A3 WO 0149847A3
Authority
WO
WIPO (PCT)
Prior art keywords
polynucleotides
invention further
transmembrane
receptor polypeptides
coupled receptors
Prior art date
Application number
PCT/US2000/035309
Other languages
French (fr)
Other versions
WO2001049847A2 (en
WO2001049847A9 (en
Inventor
Maria Alexandra Glucksmann
David White
Original Assignee
Millennium Pharm Inc
Maria Alexandra Glucksmann
David White
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Maria Alexandra Glucksmann, David White filed Critical Millennium Pharm Inc
Priority to AU24581/01A priority Critical patent/AU2458101A/en
Priority to EP00988366A priority patent/EP1246916A2/en
Publication of WO2001049847A2 publication Critical patent/WO2001049847A2/en
Publication of WO2001049847A3 publication Critical patent/WO2001049847A3/en
Publication of WO2001049847A9 publication Critical patent/WO2001049847A9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

The present invention relates to seven-transmembrane proteins, including proteins that function as receptors belonging to the superfamily of G-protein-coupled receptors. The invention also relates to polynucleotides encoding the seven-transmembrane proteins/receptors. The invention further relates to methods using the seven-transmembrane protein/receptor polypeptides and polynucleotides as a target for diagnosis and treatment in seven-transmembrane protein/receptor-mediated and related disorders. The invention further relates to drug-screening methods using the seven-transmembrane protein/receptor polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the seven-transmembrane protein/receptor polypeptides and polynucleotides. The invention further relates to procedures for producing the receptor polypeptides and polynucleotides.
PCT/US2000/035309 1999-12-30 2000-12-22 26904, 38911, and 39404, seven-transmembrane proteins/g-protein coupled receptors WO2001049847A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU24581/01A AU2458101A (en) 1999-12-30 2000-12-22 26904, 38911, and 39404, novel seven-transmembrane proteins/g-protein coupled receptors
EP00988366A EP1246916A2 (en) 1999-12-30 2000-12-22 26904, 38911, and 39404, seven-transmembrane proteins / g-protein coupled receptors

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47579099A 1999-12-30 1999-12-30
US09/475,790 1999-12-30

Publications (3)

Publication Number Publication Date
WO2001049847A2 WO2001049847A2 (en) 2001-07-12
WO2001049847A3 true WO2001049847A3 (en) 2002-05-30
WO2001049847A9 WO2001049847A9 (en) 2002-06-27

Family

ID=23889162

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/035309 WO2001049847A2 (en) 1999-12-30 2000-12-22 26904, 38911, and 39404, seven-transmembrane proteins/g-protein coupled receptors

Country Status (3)

Country Link
EP (1) EP1246916A2 (en)
AU (1) AU2458101A (en)
WO (1) WO2001049847A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2388865A1 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Novel g protein-coupled receptors
GB2365012A (en) * 2000-05-11 2002-02-13 Smithkline Beecham Corp G protein coupled receptor AXOR89
JP2005506031A (en) * 2000-05-18 2005-03-03 アプレラ コーポレーション Isolated human G-protein coupled receptor, nucleic acid molecule encoding human GPCR protein, and uses thereof
AU2001295454A1 (en) * 2000-08-14 2002-02-25 Bayer Aktiengesellschaft Regulation of human p2y1-like g protein-coupled receptor
EP1688496A3 (en) * 2000-08-14 2006-08-16 Actimis Pharmaceuticals, Inc., Regulation of human P2Y1-like G protein-coupled receptor
GB0120704D0 (en) * 2000-09-01 2001-10-17 Glaxo Group Ltd Polypeptide
WO2002038767A2 (en) * 2000-11-07 2002-05-16 Genetics Institute, Llc. G protein-coupled receptor protein and nucleic acid molecules and uses therefor
US7312086B2 (en) 2000-12-07 2007-12-25 Bristol-Myers Squibb Company Methods of diagnosing colon adenocarcinoma using the human g-protein coupled receptor hgprbmy23
EP1219638A3 (en) * 2000-12-18 2002-07-24 Pfizer Limited G-protein coupled receptors having homology to the P2Y purinoreceptor 1 (P2Y1)
WO2002057441A1 (en) * 2001-01-18 2002-07-25 Takeda Chemical Industries, Ltd. Novel g protein-coupled receptor protein and dna thereof
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
STADEL ET AL.: "Orphan G protein-coupled receptors:", TRENDS IN PHARMACOLOGICAL SCIENCES, no. 18, 1 November 1997 (1997-11-01), pages 430 - 437, XP002073279, ISSN: 0165-6147 *

Also Published As

Publication number Publication date
EP1246916A2 (en) 2002-10-09
WO2001049847A2 (en) 2001-07-12
WO2001049847A9 (en) 2002-06-27
AU2458101A (en) 2001-07-16

Similar Documents

Publication Publication Date Title
WO2000023588A8 (en) G-protein coupled receptors
WO2000000611A3 (en) 14273 receptor, a g-protein coupled receptor
WO2001059117A3 (en) Seven-transmembrane proteins/g-protein coupled receptors
WO2001098351A3 (en) G-protein coupled receptors
WO1998031799A3 (en) Polynucleotides and polypeptides encoding receptors
WO2001049847A3 (en) 26904, 38911, and 39404, seven-transmembrane proteins/g-protein coupled receptors
WO2001042288A3 (en) G-protein coupled receptors
AU5608000A (en) 22025, a novel human cyclic nucleotide phosphodiesterase
WO1999063087A8 (en) G-protein coupled receptor, named 2871 receptor
WO2001057085A3 (en) G-protein coupled receptors
WO2000050596A3 (en) 14273 receptor, a novel g-protein coupled receptor
WO2001087937A3 (en) G-protein coupled receptors
AU1712200A (en) G-protein coupled receptors, homologous to ebv-induced gpcr 2 (ebi-2). methods to seek for ligands thereof
WO2001098323A8 (en) G-protein coupled receptors
WO2003002604A3 (en) G protein coupled receptors and dna sequences thereof
WO2003018798A3 (en) G-protein coupled receptor and dna sequences thereof
WO2002102839A3 (en) Novel g-protein coupled receptors and dna sequences thereof
WO2000050563A3 (en) G protein-coupled receptor resembling galanin receptors
WO2000020590A3 (en) G-protein coupled receptor proteins
WO2001002567A8 (en) 16405 receptor, a g-protein coupled receptor
WO2001072836A3 (en) G-protein coupled receptors
WO2000032774A8 (en) 12216 receptor, a g-protein coupled receptor
WO2002026825A3 (en) G-protein coupled receptors
WO2003027254A3 (en) 15625 receptor, a novel g-protein coupled receptor
WO2001059116A3 (en) 19459 protein, a human g-protein coupled seven transmembrane receptor

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ CZ DE DE DK DK DM DZ EE EE ES FI FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ CZ DE DE DK DK DM DZ EE EE ES FI FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

AK Designated states

Kind code of ref document: C2

Designated state(s): AE AG AL AM AT AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ CZ DE DE DK DK DM DZ EE EE ES FI FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: C2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

COP Corrected version of pamphlet

Free format text: PAGES 1/22-22/22, DRAWINGS, REPLACED BY NEW PAGES 1/22-22/22; DUE TO LATE TRANSMITTAL BY THE RECEIVING OFFICE

WWE Wipo information: entry into national phase

Ref document number: 2000988366

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2000988366

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

NENP Non-entry into the national phase

Ref country code: JP