WO2000032774A8 - 12216 receptor, a g-protein coupled receptor - Google Patents

12216 receptor, a g-protein coupled receptor

Info

Publication number
WO2000032774A8
WO2000032774A8 PCT/US1999/028090 US9928090W WO0032774A8 WO 2000032774 A8 WO2000032774 A8 WO 2000032774A8 US 9928090 W US9928090 W US 9928090W WO 0032774 A8 WO0032774 A8 WO 0032774A8
Authority
WO
WIPO (PCT)
Prior art keywords
receptor
polynucleotides
invention further
relates
receptor polypeptides
Prior art date
Application number
PCT/US1999/028090
Other languages
French (fr)
Other versions
WO2000032774A1 (en
WO2000032774A9 (en
Inventor
Maria Alexandra Glucksmann
Myoung Chun
Original Assignee
Millennium Pharm Inc
Maria Alexandra Glucksmann
Myoung Chun
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Maria Alexandra Glucksmann, Myoung Chun filed Critical Millennium Pharm Inc
Priority to AU21590/00A priority Critical patent/AU2159000A/en
Priority to EP99965917A priority patent/EP1135492A1/en
Publication of WO2000032774A1 publication Critical patent/WO2000032774A1/en
Publication of WO2000032774A8 publication Critical patent/WO2000032774A8/en
Publication of WO2000032774A9 publication Critical patent/WO2000032774A9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention relates to a receptor belonging to the superfamily of G-protein-coupled receptors. The invention also relates to polynucleotides encoding the receptor. The invention further relates to methods using the receptor polypeptides and polynucleotides as a target for diagnosis and treatment in receptor-medicated disorders. The invention further relates to drug-screening methods using the receptor polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the receptor polypeptides and polynucleotides. The invention further relates to procedures for producing the receptor polypeptides and polynucleotides.
PCT/US1999/028090 1998-11-25 1999-11-24 12216 receptor, a g-protein coupled receptor WO2000032774A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU21590/00A AU2159000A (en) 1998-11-25 1999-11-24 12216 receptor, a g-protein coupled receptor
EP99965917A EP1135492A1 (en) 1998-11-25 1999-11-24 12216 receptor, a g-protein coupled receptor

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20030298A 1998-11-25 1998-11-25
US09/200,302 1998-11-25
US44868799A 1999-11-24 1999-11-24
US09/448,687 1999-11-24

Publications (3)

Publication Number Publication Date
WO2000032774A1 WO2000032774A1 (en) 2000-06-08
WO2000032774A8 true WO2000032774A8 (en) 2001-02-15
WO2000032774A9 WO2000032774A9 (en) 2002-04-11

Family

ID=26895645

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/028090 WO2000032774A1 (en) 1998-11-25 1999-11-24 12216 receptor, a g-protein coupled receptor

Country Status (2)

Country Link
EP (1) EP1135492A1 (en)
WO (1) WO2000032774A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1073681A4 (en) * 1998-04-24 2005-01-12 Smithkline Beecham Corp Cloning of a novel 7tm receptor axor-2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002502589A (en) * 1998-02-09 2002-01-29 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド 45 human secreted proteins
ES2264267T3 (en) * 1998-03-12 2006-12-16 Astellas Pharma Inc. NEW PROTEINS OF RECEPTORS COPULATED TO PROTEINA G.
EP1073681A4 (en) * 1998-04-24 2005-01-12 Smithkline Beecham Corp Cloning of a novel 7tm receptor axor-2

Also Published As

Publication number Publication date
EP1135492A1 (en) 2001-09-26
WO2000032774A1 (en) 2000-06-08
WO2000032774A9 (en) 2002-04-11

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