WO2001048244A3 - Detection of single nucleotide polymorphisms - Google Patents

Detection of single nucleotide polymorphisms Download PDF

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Publication number
WO2001048244A3
WO2001048244A3 PCT/US2000/034935 US0034935W WO0148244A3 WO 2001048244 A3 WO2001048244 A3 WO 2001048244A3 US 0034935 W US0034935 W US 0034935W WO 0148244 A3 WO0148244 A3 WO 0148244A3
Authority
WO
WIPO (PCT)
Prior art keywords
detection
single nucleotide
nucleotide polymorphisms
nucleic acid
solid support
Prior art date
Application number
PCT/US2000/034935
Other languages
French (fr)
Other versions
WO2001048244A2 (en
Inventor
Warren Michael Casey
Jingwen Chen
Heidi M Colton
David Taylor
Michael Phillip Weiner
Original Assignee
Glaxo Group Ltd
Warren Michael Casey
Jingwen Chen
Heidi M Colton
David Taylor
Michael Phillip Weiner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Warren Michael Casey, Jingwen Chen, Heidi M Colton, David Taylor, Michael Phillip Weiner filed Critical Glaxo Group Ltd
Priority to EP00988273A priority Critical patent/EP1272662A2/en
Priority to AU24500/01A priority patent/AU2450001A/en
Priority to CA002396010A priority patent/CA2396010A1/en
Priority to JP2001548756A priority patent/JP2003522527A/en
Publication of WO2001048244A2 publication Critical patent/WO2001048244A2/en
Publication of WO2001048244A3 publication Critical patent/WO2001048244A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Provided is a method of identifying a selected nucleotide in a first nucleic acid utilizing a mobile solid support, as well as a novel read-out method for improving the use of mobile solid support-based read-out technologies for detection of nucleic acid polymorphisms in a target nucleic acid.
PCT/US2000/034935 1999-12-28 2000-12-21 Detection of single nucleotide polymorphisms WO2001048244A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP00988273A EP1272662A2 (en) 1999-12-28 2000-12-21 Detection of single nucleotide polymorphisms
AU24500/01A AU2450001A (en) 1999-12-28 2000-12-21 Detection of single nucleotide polymorphisms
CA002396010A CA2396010A1 (en) 1999-12-28 2000-12-21 Detection of single nucleotide polymorphisms
JP2001548756A JP2003522527A (en) 1999-12-28 2000-12-21 Single nucleotide polymorphism detection

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17326899P 1999-12-28 1999-12-28
US60/173,268 1999-12-28

Publications (2)

Publication Number Publication Date
WO2001048244A2 WO2001048244A2 (en) 2001-07-05
WO2001048244A3 true WO2001048244A3 (en) 2002-11-14

Family

ID=22631246

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/034935 WO2001048244A2 (en) 1999-12-28 2000-12-21 Detection of single nucleotide polymorphisms

Country Status (5)

Country Link
EP (1) EP1272662A2 (en)
JP (1) JP2003522527A (en)
AU (1) AU2450001A (en)
CA (1) CA2396010A1 (en)
WO (1) WO2001048244A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10029914A1 (en) * 2000-06-19 2002-01-03 Epigenomics Ag Method for the highly parallel analysis of polymorphisms
AUPS276402A0 (en) 2002-06-04 2002-06-27 Walter And Eliza Hall Institute Of Medical Research, The A nucleic acid anchoring system
US20040157238A1 (en) * 2002-09-20 2004-08-12 Quinn John J. Method for detection of multiple nucleic acid sequence variations
US7670771B2 (en) 2004-01-21 2010-03-02 University Of Utah Research Foundation Mutant sodium channel Nav1.7 nucleic acid methods
JP4769041B2 (en) * 2004-07-28 2011-09-07 株式会社ビー・エム・エル Mycobacterial bacteria identification kit
JP5519964B2 (en) * 2008-06-30 2014-06-11 ユニバーサル・バイオ・リサーチ株式会社 Substrates for gene analysis
WO2015200855A1 (en) 2014-06-26 2015-12-30 University Of Florida Research Foundation, Inc. Rapid detection of infectious agents

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025563A1 (en) * 1992-06-17 1993-12-23 City Of Hope A method of detecting and discriminating between nucleic acid sequences
WO1997022719A1 (en) * 1995-12-18 1997-06-26 Washington University Method for nucleic acid analysis using fluorescence resonance energy transfer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025563A1 (en) * 1992-06-17 1993-12-23 City Of Hope A method of detecting and discriminating between nucleic acid sequences
WO1997022719A1 (en) * 1995-12-18 1997-06-26 Washington University Method for nucleic acid analysis using fluorescence resonance energy transfer

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CAI ET AL.: "Flow cytometry-based DNA hybridization and polymorphism analysis", PROC SPIE-INT SOC OPT ENG (ADVANCES IN OPTICAL BIOPHYSICS), vol. 3256, 1998, pages 171 - 177, XP001064684 *
COLE ET AL.: "Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence", NATURE, vol. 393, 1998, pages 537 - 544, XP002144873 *
DATABASE EMBL [online] 11 June 1998 (1998-06-11), PARKHILL J.: "Mycobacterium tuberculosis H37Rv complete genome; segment 84/162", XP002207118, Database accession no. Z83859 *
FULTON R JERROLD ET AL: "Advanced multiplexed analysis with the FlowMetrix system.", CLINICAL CHEMISTRY, vol. 43, no. 9, 1997, pages 1749 - 1756, XP002142645, ISSN: 0009-9147 *
SHOEMAKER D D ET AL: "QUANTITATIVE PHENOTYPIC ANALYSIS OF YEAST DELETION MUTANTS USING A HIGHLY PARALLEL MOLECULAR BAR-CODING STRATEGY", NATURE GENETICS, NEW YORK, NY, US, vol. 14, no. 4, 1 December 1996 (1996-12-01), pages 450 - 456, XP002043431, ISSN: 1061-4036 *

Also Published As

Publication number Publication date
WO2001048244A2 (en) 2001-07-05
EP1272662A2 (en) 2003-01-08
AU2450001A (en) 2001-07-09
CA2396010A1 (en) 2001-07-05
JP2003522527A (en) 2003-07-29

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