WO2001043755A3 - Regenerationshilfsmittel (3-wege-hahn) - Google Patents

Regenerationshilfsmittel (3-wege-hahn) Download PDF

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Publication number
WO2001043755A3
WO2001043755A3 PCT/EP2000/012802 EP0012802W WO0143755A3 WO 2001043755 A3 WO2001043755 A3 WO 2001043755A3 EP 0012802 W EP0012802 W EP 0012802W WO 0143755 A3 WO0143755 A3 WO 0143755A3
Authority
WO
WIPO (PCT)
Prior art keywords
container
adjuvant
regenerative
centrifuge
radially inner
Prior art date
Application number
PCT/EP2000/012802
Other languages
English (en)
French (fr)
Other versions
WO2001043755A2 (de
Inventor
Guenter Uhr
Original Assignee
Curasan Ag
Guenter Uhr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curasan Ag, Guenter Uhr filed Critical Curasan Ag
Priority to AU23658/01A priority Critical patent/AU2365801A/en
Priority to EP00987405A priority patent/EP1237560A2/de
Priority to CA002394798A priority patent/CA2394798A1/en
Publication of WO2001043755A2 publication Critical patent/WO2001043755A2/de
Publication of WO2001043755A3 publication Critical patent/WO2001043755A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Abstract

Die Erfindung betrifft ein Regenerationshilfsmittel bei Haut- und Knochendefekten an Lebewesen sowie ein Verfahren, das ohne Speziallabor in jeder Arztpraxis durchführbar ist, entsprechend einfach handhabbar soll auch der hierfür zu verwendende Bausatz ausgebildet sein. Ein erfindungsgemässes Regenerationshilfsmittel für Haut- und Knochendefekte weist thrombozytenreiches Plasma (Platelet-Rich-Plasma) und Calciumphosphate auf. Ein erfindungsgemässes Verfahren hat folgende Schritte: Aufziehen von Blut in einen Behälter, Einspannen in eine Zentrifuge, Durchführen eines ersten Zentrifugierschrittes, Entnahme des Behälters aus der Zentrifuge und der radial inneren Fraktion aus dem Behälter und Überführen in einen zweiten Behälter, Einspannen dessen in die Zentrifuge, Durchführen eines zweiten Zentrifugierschrittes bei wesentlich höherer Drehzahl, Entnahme dieses Behälters aus der Zentrifuge, Entnehmen eines Teils der radial innen liegenden Fraktion aus dem zweiten Behälter, Vermischen der radial äusseren Fraktion mit dem Rest der radial inneren Fraktion im zweiten Röhrchen zu PRP-Plasma und Vermengen dieses Inhaltes des zweiten Behälters mit einem Knochenersatzmittel.
PCT/EP2000/012802 1999-12-15 2000-12-15 Regenerationshilfsmittel (3-wege-hahn) WO2001043755A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU23658/01A AU2365801A (en) 1999-12-15 2000-12-15 Regenerative adjuvant (3-way tap)
EP00987405A EP1237560A2 (de) 1999-12-15 2000-12-15 Regenerationshilfsmittel (3-wege-hahn)
CA002394798A CA2394798A1 (en) 1999-12-15 2000-12-15 Regenerative adjuvant (3-way tap)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19960490.8 1999-12-15
DE19960490A DE19960490A1 (de) 1999-12-15 1999-12-15 Regenerationsmittel

Publications (2)

Publication Number Publication Date
WO2001043755A2 WO2001043755A2 (de) 2001-06-21
WO2001043755A3 true WO2001043755A3 (de) 2002-02-28

Family

ID=7932758

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/012802 WO2001043755A2 (de) 1999-12-15 2000-12-15 Regenerationshilfsmittel (3-wege-hahn)

Country Status (6)

Country Link
US (1) US20030180274A1 (de)
EP (1) EP1237560A2 (de)
AU (1) AU2365801A (de)
CA (1) CA2394798A1 (de)
DE (1) DE19960490A1 (de)
WO (1) WO2001043755A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003015800A1 (en) 2001-08-09 2003-02-27 Ivoclar Vivadent, Inc. Tissue implants and methods for making and using same
ES2273574B1 (es) * 2005-06-01 2008-04-01 Maria Jesus Vicente Lobera Metodo para la preparacion de sueros o plasmas autologos ricos en factores de crecimiento.
GB2504679A (en) 2012-08-03 2014-02-12 Nobel Biocare Services Ag Bone substitute structure and material

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984001805A1 (en) * 1982-11-01 1984-05-10 Allan M Parham Medical stopcock valve assembly
WO1996017871A1 (en) * 1994-12-07 1996-06-13 Plasmaseal Corporation Plasma concentrate and tissue sealant compositions
WO1996023039A1 (en) * 1995-01-23 1996-08-01 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives
WO1996029113A1 (en) * 1995-03-20 1996-09-26 Medimop Medical Projects Ltd. Fluid control device
WO1997015340A1 (en) * 1995-10-24 1997-05-01 Astra Pharmaceuticals Pty. Ltd. Tamper evident syringe design
WO1997040864A1 (en) * 1996-04-30 1997-11-06 Medtronic, Inc. Method for making autologous fibrin sealant
DE19733899A1 (de) * 1997-08-05 1999-02-11 Ingo Flesch Verfahren und Vorrichtung zur Herstellung autologer, thrombozytärer Wachstumsfaktoren sowie System als Bestandteil einer Vorrichtung zur Herstellung autologer, thrombozytärer Wachtstumsfaktoren

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4445030A1 (de) * 1994-12-16 1996-06-27 Heraeus Instr Gmbh Zentrifugierbare medizinische Vorrichtung
US5614206A (en) * 1995-03-07 1997-03-25 Wright Medical Technology, Inc. Controlled dissolution pellet containing calcium sulfate
US5824084A (en) * 1996-07-03 1998-10-20 The Cleveland Clinic Foundation Method of preparing a composite bone graft
US6322785B1 (en) * 1999-03-02 2001-11-27 Natrex Technologies Methods and compositions for bone graft implants

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1984001805A1 (en) * 1982-11-01 1984-05-10 Allan M Parham Medical stopcock valve assembly
WO1996017871A1 (en) * 1994-12-07 1996-06-13 Plasmaseal Corporation Plasma concentrate and tissue sealant compositions
WO1996023039A1 (en) * 1995-01-23 1996-08-01 The Regents Of The University Of California Plasma and polymer containing surgical hemostatic adhesives
WO1996029113A1 (en) * 1995-03-20 1996-09-26 Medimop Medical Projects Ltd. Fluid control device
WO1997015340A1 (en) * 1995-10-24 1997-05-01 Astra Pharmaceuticals Pty. Ltd. Tamper evident syringe design
WO1997040864A1 (en) * 1996-04-30 1997-11-06 Medtronic, Inc. Method for making autologous fibrin sealant
DE19733899A1 (de) * 1997-08-05 1999-02-11 Ingo Flesch Verfahren und Vorrichtung zur Herstellung autologer, thrombozytärer Wachstumsfaktoren sowie System als Bestandteil einer Vorrichtung zur Herstellung autologer, thrombozytärer Wachtstumsfaktoren

Also Published As

Publication number Publication date
CA2394798A1 (en) 2001-06-21
DE19960490A1 (de) 2001-07-12
EP1237560A2 (de) 2002-09-11
WO2001043755A2 (de) 2001-06-21
US20030180274A1 (en) 2003-09-25
AU2365801A (en) 2001-06-25

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