WO2001036639A3 - Bt toxin receptors from lepidopteran insects and methods of use - Google Patents

Bt toxin receptors from lepidopteran insects and methods of use Download PDF

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Publication number
WO2001036639A3
WO2001036639A3 PCT/US2000/031674 US0031674W WO0136639A3 WO 2001036639 A3 WO2001036639 A3 WO 2001036639A3 US 0031674 W US0031674 W US 0031674W WO 0136639 A3 WO0136639 A3 WO 0136639A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
lepidopteran insects
toxin receptors
toxin
novel
Prior art date
Application number
PCT/US2000/031674
Other languages
French (fr)
Other versions
WO2001036639A2 (en
Inventor
Ronald D Flannagan
John P Mathis
Terry Euclaire Meyer
Original Assignee
Pioneer Hi Bred Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pioneer Hi Bred Int filed Critical Pioneer Hi Bred Int
Priority to JP2001538518A priority Critical patent/JP2003514531A/en
Priority to EP00979198A priority patent/EP1230365A2/en
Priority to AU16603/01A priority patent/AU783296C/en
Priority to CA002391384A priority patent/CA2391384C/en
Publication of WO2001036639A2 publication Critical patent/WO2001036639A2/en
Publication of WO2001036639A3 publication Critical patent/WO2001036639A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention relates to Bt toxin resistance management. The invention particularly relates to the isolation and characterization of nucleic acid and polypeptides for a novel Bt toxin receptor. The nucleic acid and polypeptides are useful in identifying and designing novel Bt toxin receptor ligands including novel insecticidal toxins.
PCT/US2000/031674 1999-11-18 2000-11-17 Bt toxin receptors from lepidopteran insects and methods of use WO2001036639A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2001538518A JP2003514531A (en) 1999-11-18 2000-11-17 BT toxin receptor from lepidopteran insects and methods of use
EP00979198A EP1230365A2 (en) 1999-11-18 2000-11-17 Bt toxin receptors from lepidopteran insects and methods of use
AU16603/01A AU783296C (en) 1999-11-18 2000-11-17 BT toxin receptors from lepidopteran insects and methods of use
CA002391384A CA2391384C (en) 1999-11-18 2000-11-17 Bt toxin receptors from lepidopteran insects and methods of use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US16628599P 1999-11-18 1999-11-18
US60/166,285 1999-11-18
US23409900P 2000-09-21 2000-09-21
US60/234,099 2000-09-21

Publications (2)

Publication Number Publication Date
WO2001036639A2 WO2001036639A2 (en) 2001-05-25
WO2001036639A3 true WO2001036639A3 (en) 2001-11-22

Family

ID=26862138

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/031674 WO2001036639A2 (en) 1999-11-18 2000-11-17 Bt toxin receptors from lepidopteran insects and methods of use

Country Status (5)

Country Link
EP (1) EP1230365A2 (en)
JP (1) JP2003514531A (en)
AU (1) AU783296C (en)
CA (1) CA2391384C (en)
WO (1) WO2001036639A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7029851B2 (en) 2001-03-15 2006-04-18 Clemson University Polynucleotide encoding a gene conferring resistance to Bacillus thuringiensis toxins

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208588B2 (en) 2003-03-14 2007-04-24 Pioneer Hi-Bred International, Inc. Bt toxin receptors and methods of use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996012964A1 (en) * 1994-10-19 1996-05-02 University Of Wyoming Receptor for a bacillus thuringiensis toxin
WO2001034807A2 (en) * 1999-10-26 2001-05-17 Bulla Lee A Jr Pectinophora gossypiella (pink bollworm) bacillus thuringiensis toxin receptor bt-r¿2?

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996012964A1 (en) * 1994-10-19 1996-05-02 University Of Wyoming Receptor for a bacillus thuringiensis toxin
WO2001034807A2 (en) * 1999-10-26 2001-05-17 Bulla Lee A Jr Pectinophora gossypiella (pink bollworm) bacillus thuringiensis toxin receptor bt-r¿2?

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
GARCZYNSKI S F ET AL: "IDENTIFICATION OF PUTATIVE INSECT BRUSH BORDER MEMBRANE-BINDING MOLECULES SPECIFIC TO BACILLUS-THURINGIENSIS DELTA ENDOTOXIN BY PROTEIN BLOT ANALYSIS", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 57, no. 10, 1991, pages 2816 - 2820, XP000992668, ISSN: 0099-2240 *
GILL SARJEET S ET AL: "Identification, isolation, and cloning of a Bacillus thuringiensis CryIAc toxin-binding protein from the midgut of the lepidopteran insect Heliothis virescens.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 45, 1995, pages 27277 - 27282, XP002164763, ISSN: 0021-9258 *
KEETON TIMOTHY P ET AL: "Effects of midgut-protein-preparative and ligand binding procedures on the toxin binding characteristics of BT-R1, a common high-affinity receptor in Manduca sexta for Cry1A Bacillus thuringiensis toxins.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 64, no. 6, June 1998 (1998-06-01), pages 2158 - 2165, XP002164762, ISSN: 0099-2240 *
KEETON TIMOTHY P ET AL: "Ligand specificity and affinity of BT-R-1, the Bacillus thuringiensis Cry1A toxin receptor from Manduca sexta, expressed in mammalian and insect cell cultures.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 63, no. 9, 1997, pages 3419 - 3425, XP002164761, ISSN: 0099-2240 *
LEE MI KYONG ET AL: "Aminopeptidase N purified from gypsy moth brush border membrane vesicles is a specific receptor for Bacillus thuringiensis CryIAc toxin.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 62, no. 8, 1996, pages 2845 - 2849, XP002164764, ISSN: 0099-2240 *
NAGAMATSU YASUNORI ET AL: "Cloning, sequencing, and expression of the Bombyx mori receptor for Bacillus thuringiensis insecticidal CryIA(a) toxin.", BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, vol. 62, no. 4, April 1998 (1998-04-01), pages 727 - 734, XP002164759, ISSN: 0916-8451 *
OLTEAN DANIELA I ET AL: "Partial purification and characterization of Bacillus thuringiensis Cry1A toxin receptor A from Heliothis virescens and cloning of the corresponding cDNA.", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 65, no. 11, November 1999 (1999-11-01), pages 4760 - 4766, XP002169506, ISSN: 0099-2240 *
VADLAMUDI RATNA K ET AL: "Cloning and expression of a receptor for an insecticidal toxin of Bacillus thuringiensis.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 10, 1995, pages 5490 - 5494, XP002164760, ISSN: 0021-9258 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7029851B2 (en) 2001-03-15 2006-04-18 Clemson University Polynucleotide encoding a gene conferring resistance to Bacillus thuringiensis toxins

Also Published As

Publication number Publication date
JP2003514531A (en) 2003-04-22
AU783296B2 (en) 2005-10-13
EP1230365A2 (en) 2002-08-14
CA2391384A1 (en) 2001-05-25
AU783296C (en) 2006-09-07
CA2391384C (en) 2007-05-01
WO2001036639A2 (en) 2001-05-25
AU1660301A (en) 2001-05-30

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