WO2001030263A1 - Medication retention assembly for oral delivery tray - Google Patents
Medication retention assembly for oral delivery tray Download PDFInfo
- Publication number
- WO2001030263A1 WO2001030263A1 PCT/US2000/001411 US0001411W WO0130263A1 WO 2001030263 A1 WO2001030263 A1 WO 2001030263A1 US 0001411 W US0001411 W US 0001411W WO 0130263 A1 WO0130263 A1 WO 0130263A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- substrate
- medication
- adhesive
- layer
- tab portion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C19/00—Dental auxiliary appliances
- A61C19/06—Implements for therapeutic treatment
- A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/0092—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine for holding medicines in, or fixing medicines on, a tooth, e.g. holder containing medicines fixed on a tooth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
Definitions
- the direct application of a medicant to oral structures is generally unsatisfactory because the medication typically does not remain on the oral structure for a significant length of time.
- the length of time is variable and may depend on factors such as the viscosity of the medication, the presence of saliva and the ability of the patient to prevent adjacent soft tissues such as inner surfaces of the labia or lips and bucca or cheeks from contacting the tray containing the medication.
- the effectiveness of the medication is substantially diminished if the medication is prematurely removed from the oral structure under treatment.
- the dental tray described in that reference has one or more medication reservoirs that each include a plurality of discreet support members projecting away from the reservoir to engage the dental structure of the patient.
- the support members are arranged to resist the flow of medication such as bleaching solution in a gingival direction so that retention of the solution in the tray is enhanced.
- the protrusions 22 are constructed of a hydrophilic material.
- the tab portion may be integral with the layer of adhesive.
- a layer of adhesive 14a may be integrally joined in end-to-end relationship with a tab portion 18a.
- the layer of adhesive 14a may comprise a section of double-sided tape as described above with a membrane and a coating of adhesive on opposite faces of the membrane.
- the layer of adhesive 14a is releasably connected to a substrate 12a that is identical to the substrate 12 described above.
- the tab portion 18a may be trimmed from the membrane once the layer of adhesive 14a has been detached from an adjacent release liner 16a.
- the substrate 12 and the layer of adhesive 14 are placed on the model 26.
- the practitioner places the notch 24 along the midline (i.e., in the mesial-distal center of the dental arch of the model 26), so that the substrate 12 is properly centered on the model 26.
- the notch 24 provides a visual alignment guide to facilitate placement of the substrate 12 on the model 26.
- the substrate 12 is aligned to the mid-third of the teeth of the model 26 in an occlusal-gingival direction as shown in Fig.
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dentistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE60019949T DE60019949T2 (de) | 1999-10-22 | 2000-01-20 | Arzneimittel enthaltendes system zur oralen abgabevorrichtung |
| CA002386840A CA2386840A1 (en) | 1999-10-22 | 2000-01-20 | Medication retention assembly for oral delivery tray |
| JP2001532686A JP4119124B2 (ja) | 1999-10-22 | 2000-01-20 | 口腔デリバリートレー用薬剤保持アセンブリ |
| AU28541/00A AU2854100A (en) | 1999-10-22 | 2000-01-20 | Medication retention assembly for oral delivery tray |
| EP00906967A EP1221907B1 (en) | 1999-10-22 | 2000-01-20 | Medication retention assembly for oral delivery tray |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/426,123 | 1999-10-22 | ||
| US09/426,123 US6322360B1 (en) | 1999-10-22 | 1999-10-22 | Medication retention assembly for oral delivery tray |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2001030263A1 true WO2001030263A1 (en) | 2001-05-03 |
Family
ID=23689404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2000/001411 Ceased WO2001030263A1 (en) | 1999-10-22 | 2000-01-20 | Medication retention assembly for oral delivery tray |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6322360B1 (enExample) |
| EP (1) | EP1221907B1 (enExample) |
| JP (1) | JP4119124B2 (enExample) |
| AU (1) | AU2854100A (enExample) |
| CA (1) | CA2386840A1 (enExample) |
| DE (1) | DE60019949T2 (enExample) |
| WO (1) | WO2001030263A1 (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6551579B2 (en) * | 1997-06-06 | 2003-04-22 | The Procter & Gamble Company | Delivery systems for a tooth whitener |
| US6884426B2 (en) | 1997-06-06 | 2005-04-26 | The Procter & Gamble Co. | Methods for whitening teeth |
| US6949240B2 (en) | 2002-05-23 | 2005-09-27 | The Procter & Gamble Company | Tooth whitening products |
| JP2006515790A (ja) * | 2003-01-24 | 2006-06-08 | ウルトラデント プロダクツ インコーポレイテッド | 予め成形されたデンタルトレイ及び処置装置並びにかかるデンタルトレイを利用する方法 |
| US9554976B2 (en) | 2002-09-11 | 2017-01-31 | The Procter & Gamble Company | Tooth whitening product |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6582708B1 (en) | 2000-06-28 | 2003-06-24 | The Procter & Gamble Company | Tooth whitening substance |
| CN1204875C (zh) | 1999-07-02 | 2005-06-08 | 宝洁公司 | 使用可取出的背衬带的含有机硅氧烷树脂的口腔护理组合物的释放系统 |
| US6945778B2 (en) * | 2002-08-20 | 2005-09-20 | Ultradent Products, Inc. | Customized dental trays comprising ultra low density polyethylene and methods for making and using such trays |
| US6848905B2 (en) | 2002-08-20 | 2005-02-01 | Archtek, Inc. | Method of making a dental tray using a patient's teeth as a template |
| US6969255B2 (en) * | 2002-08-20 | 2005-11-29 | Archtek, Inc. | Preformed tray comprising ultra low density polyethylene |
| US6984128B2 (en) * | 2002-11-01 | 2006-01-10 | Bas Medical, Inc. | Methods for enabling and stabilizing tooth movement |
| US7004756B2 (en) | 2003-01-24 | 2006-02-28 | Ultradent Products, Inc. | Pre-shaped dental trays and treatment devices and methods that utilize such dental trays |
| US20040214140A1 (en) * | 2003-04-25 | 2004-10-28 | Ultradent Products, Inc. | Anatomical preformed tray incorporating a severable handle |
| US7040897B2 (en) * | 2003-05-23 | 2006-05-09 | Ultradent Products, Inc. | Thin, flexible membrane dental trays and systems and methods utilizing such trays |
| US7074042B2 (en) | 2003-05-27 | 2006-07-11 | Ultradent Products, Inc. | Tray-like dental bleaching devices having a barrier layer and a substantially solid bleaching composition |
| US7056118B2 (en) | 2003-05-27 | 2006-06-06 | Ultradent Products, Inc. | Compositions and devices having a tray-like configuration for delivering a medicament and methods of manufacturing and using such compositions and devices |
| US7011523B2 (en) * | 2003-10-22 | 2006-03-14 | Ultradent Products, Inc. | Bleaching compositions and devices having a solid adhesive layer and bleaching gel adjacent thereto |
| US7059857B2 (en) | 2003-05-27 | 2006-06-13 | Ultradent Products, Inc. | Substantially solid desensitizing compositions and devices having a tray-like configuration and methods of manufacturing and using such compositions and devices |
| US6860736B2 (en) * | 2003-05-23 | 2005-03-01 | Ultradent Products, Inc. | Oral treatment devices that include a thin, flexible barrier layer and an endoskeleton treatment or adhesive composition |
| US7052275B2 (en) * | 2003-05-27 | 2006-05-30 | Ultradent Products, Inc. | Kits and methods for bleaching and desensitizing teeth |
| US7048543B2 (en) * | 2003-05-27 | 2006-05-23 | Ultradent Products, Inc. | Substantially solid bleaching composition in a tray-like configuration |
| US20050002975A1 (en) * | 2003-06-06 | 2005-01-06 | Densen Cao | Structures and methods for delivering topical compositions |
| US6997708B2 (en) * | 2003-10-22 | 2006-02-14 | Ultradent Products, Inc. | Treatment compositions and strips having a solid adhesive layer and treatment gel adjacent thereto |
| US6981874B2 (en) * | 2003-10-22 | 2006-01-03 | Ultradent Products, Inc. | Dental bleaching compositions and devices having a solid activation adhesive layer or region and bleaching gel layer or region |
| US7192280B2 (en) | 2004-02-19 | 2007-03-20 | Ultradent Products, Inc. | Dental bleaching devices having a protective adhesive region |
| US7059858B2 (en) | 2004-02-19 | 2006-06-13 | Ultradent Products, Inc. | Universal tray design having anatomical features to enhance fit |
| US20050287491A1 (en) * | 2004-03-18 | 2005-12-29 | Slone Charles E | Bi-laminate martix and method of use |
| US7264471B2 (en) | 2004-05-05 | 2007-09-04 | Ultradent Products, Inc. | Methods and kits for bleaching teeth while protecting adjacent gingival tissue |
| US7625210B2 (en) | 2004-08-09 | 2009-12-01 | Ultradent Products, Inc. | Treatment devices for providing oral treatments and kits and methods that utilize such treatment devices |
| US7137814B2 (en) * | 2004-10-12 | 2006-11-21 | Ultradent Products, Inc. | Dental treatment tray comprising a plasticized resin for improved moldability and conformability |
| US7168950B2 (en) | 2004-10-18 | 2007-01-30 | 3M Innovative Properties Company | Orthodontic methods and apparatus for applying a composition to a patient's teeth |
| US20060141416A1 (en) * | 2004-12-24 | 2006-06-29 | Knutson Eric J | Occlusal indicator tray & processes therefor |
| US7247022B2 (en) * | 2005-01-31 | 2007-07-24 | Ultradent Products, Inc. | Dental tray system with releasable hold inner and outer dental trays |
| US20060228307A1 (en) * | 2005-04-08 | 2006-10-12 | Cao Group, Inc. | Structures and methods for delivering topical compositions |
| US7452209B2 (en) | 2005-05-02 | 2008-11-18 | Ultradent Products, Inc. | Exoskeleton support for placement of a dental treatment strip |
| DE102006016691B4 (de) * | 2005-10-24 | 2012-10-25 | Jens Messerschmidt | Applikationsschiene für den Ober- und Unterkiefer |
| US9295619B2 (en) * | 2006-02-08 | 2016-03-29 | Cao Group, Inc. | Dental treatment compositions and conformable dental treatment trays using the same |
| US7473096B2 (en) * | 2006-06-21 | 2009-01-06 | 3M Innovative Properties Company | Orthodontic adhesive dispensing assembly |
| US8007277B2 (en) | 2006-08-25 | 2011-08-30 | Ultradent Products, Inc. | Non-custom dental treatment trays and mouth guards having improved anatomical features |
| US20100028829A1 (en) | 2008-07-31 | 2010-02-04 | Ultradent Products, Inc. | Chemically activated dental bleaching trays |
| US8202091B2 (en) * | 2007-08-31 | 2012-06-19 | Ultradent Products, Inc. | Dental treatment trays comprising silicone elastomeric material |
| US8721331B2 (en) * | 2011-10-11 | 2014-05-13 | Puthalath Koroth Raghuprasad | Oral transmucosal drug delivery device |
| WO2014060515A2 (de) * | 2012-10-17 | 2014-04-24 | Ortho Caps Gmbh | Haftpads zur fixierung eines kieferorthopädischen aligners |
| BR112015008666B1 (pt) | 2012-10-17 | 2020-04-07 | Procter & Gamble | produto extensível para tratamento dental e método de aplicação de um ativo para tratamento bucal |
Citations (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2257709A (en) * | 1938-10-14 | 1941-09-30 | Louis P Anderson | Dental appliance |
| DE1104116B (de) * | 1959-02-05 | 1961-04-06 | Dr Rudolf Eisenhut | Hilfsstreifen zum Halten der Fuellung beim Plombieren von Zaehnen |
| US4290174A (en) | 1976-08-13 | 1981-09-22 | Minnesota Mining And Manufacturing Company | Separable fastener and article for making same |
| US4968251A (en) * | 1989-07-03 | 1990-11-06 | Darnell Daniel H | Treatment of a tooth |
| US4984339A (en) | 1988-10-20 | 1991-01-15 | Velcro Industries B.V. | Hook for hook and loop fasteners |
| US5152917A (en) | 1991-02-06 | 1992-10-06 | Minnesota Mining And Manufacturing Company | Structured abrasive article |
| WO1994023610A1 (en) | 1993-04-16 | 1994-10-27 | Minnesota Mining And Manufacturing Company | Mushroom-type hook strip for a mechanical fastener |
| US5500273A (en) | 1993-06-30 | 1996-03-19 | Minnesota Mining And Manufacturing Company | Abrasive articles comprising precisely shaped particles |
| DE29607299U1 (de) * | 1996-04-11 | 1996-09-05 | Wesebaum, Burghard, 16278 Angermünde | An Zähnen haftender Träger von Wirkstoffen |
| US5626866A (en) * | 1994-03-07 | 1997-05-06 | Theratech, Inc. | Drug-containing adhesive composite transdermal delivery device |
| WO1998030381A1 (en) | 1997-01-09 | 1998-07-16 | Minnesota Mining And Manufacturing Company | Method and apparatus for capping stem fasteners |
| WO1998057564A1 (en) | 1997-06-19 | 1998-12-23 | Minnesota Mining And Manufacturing Company | Method and apparatus for forming headed stem mechanical fastener structures |
| US5891453A (en) * | 1997-06-06 | 1999-04-06 | The Procter & Gamble Company | Delivery system for a tooth whitener using a strip of material having low flexural stiffness |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1934688A (en) | 1931-02-24 | 1933-11-14 | Ackerman Edward | Dental device |
| US2963786A (en) | 1957-04-15 | 1960-12-13 | Charles C Browning | Dental partial impression tray |
| US3073300A (en) | 1961-03-24 | 1963-01-15 | Roberts Dental Mfg Co Inc | Mouth guard |
| US3247844A (en) | 1964-01-29 | 1966-04-26 | Roberts Dental Mfg Co Inc | Mouth guard |
| US3404056A (en) | 1964-07-17 | 1968-10-01 | Howmet Corp | Formation of plastic dental appliances |
| US3312218A (en) | 1965-07-16 | 1967-04-04 | Alfred G Jacobs | Mouth protector |
| US3379193A (en) | 1965-10-11 | 1968-04-23 | Richard P. Monaghan | Method of forming and using teeth covers |
| US3527219A (en) | 1967-08-21 | 1970-09-08 | Samuel Greenberg | Medicament applicator for treatment of teeth and/or gums |
| US3496936A (en) | 1967-10-31 | 1970-02-24 | Kenneth W Gores | Mouthguard |
| US3624909A (en) | 1970-05-26 | 1971-12-07 | Samuel Greenberg | Teeth gripping medicament applicator for treatment of teeth and/or gums |
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| US4044762A (en) | 1973-02-12 | 1977-08-30 | Jacobs Alfred G | Athletic mouthguard |
| US3955281A (en) | 1974-12-05 | 1976-05-11 | Pacemaker Corporation | Disposable dental tray for topical application of fluoride gel and other dental medications |
| US4138814A (en) | 1976-03-08 | 1979-02-13 | Pacemaker Corporation | Disposable dental tray for topical application of fluoride gel and other dental medications |
| US4063552A (en) | 1976-04-02 | 1977-12-20 | Going Robert E | User formed mouthguard |
| NL7709035A (nl) | 1977-08-16 | 1979-02-20 | Carpay Johannes J | Inrichting voor het behandelen van gebitten. |
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| DE3238816A1 (de) | 1982-10-20 | 1984-04-26 | geb. Schlüter Frauke Freifrau von Nostitz 8000 München Hofacker | Dentalfunktionsabdruckloeffel, verfahren und verwendung desselben zur herstellung eines funktionsmodells vom ober- bzw. unterkiefer sowie einer bissschablone |
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| US5165424A (en) | 1990-08-09 | 1992-11-24 | Silverman Harvey N | Method and system for whitening teeth |
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| US5707235A (en) | 1995-04-03 | 1998-01-13 | Knutson; Eric J. | Dental tray spacer |
| US5562449A (en) | 1995-04-18 | 1996-10-08 | Jacobs; Allison J. | Custom dental tray |
| US5816802A (en) | 1995-09-25 | 1998-10-06 | R. Eric Montgomery | Flexible dental tray |
| DE69626297T2 (de) | 1995-09-25 | 2003-12-11 | Robert Eric Montgomery | Zahnbleichende zusammensetzungen |
| US5842860A (en) | 1997-09-05 | 1998-12-01 | Funt; Lawrence A. | Medical reservoir system |
-
1999
- 1999-10-22 US US09/426,123 patent/US6322360B1/en not_active Expired - Fee Related
-
2000
- 2000-01-20 DE DE60019949T patent/DE60019949T2/de not_active Expired - Fee Related
- 2000-01-20 WO PCT/US2000/001411 patent/WO2001030263A1/en not_active Ceased
- 2000-01-20 AU AU28541/00A patent/AU2854100A/en not_active Withdrawn
- 2000-01-20 JP JP2001532686A patent/JP4119124B2/ja not_active Expired - Fee Related
- 2000-01-20 EP EP00906967A patent/EP1221907B1/en not_active Expired - Lifetime
- 2000-01-20 CA CA002386840A patent/CA2386840A1/en not_active Abandoned
Patent Citations (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2257709A (en) * | 1938-10-14 | 1941-09-30 | Louis P Anderson | Dental appliance |
| DE1104116B (de) * | 1959-02-05 | 1961-04-06 | Dr Rudolf Eisenhut | Hilfsstreifen zum Halten der Fuellung beim Plombieren von Zaehnen |
| US4290174A (en) | 1976-08-13 | 1981-09-22 | Minnesota Mining And Manufacturing Company | Separable fastener and article for making same |
| US4984339A (en) | 1988-10-20 | 1991-01-15 | Velcro Industries B.V. | Hook for hook and loop fasteners |
| US4968251A (en) * | 1989-07-03 | 1990-11-06 | Darnell Daniel H | Treatment of a tooth |
| US5152917B1 (en) | 1991-02-06 | 1998-01-13 | Minnesota Mining & Mfg | Structured abrasive article |
| US5152917A (en) | 1991-02-06 | 1992-10-06 | Minnesota Mining And Manufacturing Company | Structured abrasive article |
| WO1994023610A1 (en) | 1993-04-16 | 1994-10-27 | Minnesota Mining And Manufacturing Company | Mushroom-type hook strip for a mechanical fastener |
| US5500273A (en) | 1993-06-30 | 1996-03-19 | Minnesota Mining And Manufacturing Company | Abrasive articles comprising precisely shaped particles |
| US5626866A (en) * | 1994-03-07 | 1997-05-06 | Theratech, Inc. | Drug-containing adhesive composite transdermal delivery device |
| DE29607299U1 (de) * | 1996-04-11 | 1996-09-05 | Wesebaum, Burghard, 16278 Angermünde | An Zähnen haftender Träger von Wirkstoffen |
| WO1998030381A1 (en) | 1997-01-09 | 1998-07-16 | Minnesota Mining And Manufacturing Company | Method and apparatus for capping stem fasteners |
| US5891453A (en) * | 1997-06-06 | 1999-04-06 | The Procter & Gamble Company | Delivery system for a tooth whitener using a strip of material having low flexural stiffness |
| WO1998057564A1 (en) | 1997-06-19 | 1998-12-23 | Minnesota Mining And Manufacturing Company | Method and apparatus for forming headed stem mechanical fastener structures |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6551579B2 (en) * | 1997-06-06 | 2003-04-22 | The Procter & Gamble Company | Delivery systems for a tooth whitener |
| US6884426B2 (en) | 1997-06-06 | 2005-04-26 | The Procter & Gamble Co. | Methods for whitening teeth |
| US7122199B2 (en) | 1997-06-06 | 2006-10-17 | The Procter & Gamble Company | Methods for whitening teeth |
| US6949240B2 (en) | 2002-05-23 | 2005-09-27 | The Procter & Gamble Company | Tooth whitening products |
| US9554976B2 (en) | 2002-09-11 | 2017-01-31 | The Procter & Gamble Company | Tooth whitening product |
| US10493016B2 (en) | 2002-09-11 | 2019-12-03 | The Procter & Gamble Company | Tooth whitening product |
| JP2006515790A (ja) * | 2003-01-24 | 2006-06-08 | ウルトラデント プロダクツ インコーポレイテッド | 予め成形されたデンタルトレイ及び処置装置並びにかかるデンタルトレイを利用する方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2386840A1 (en) | 2001-05-03 |
| DE60019949D1 (de) | 2005-06-09 |
| AU2854100A (en) | 2001-05-08 |
| EP1221907A1 (en) | 2002-07-17 |
| US6322360B1 (en) | 2001-11-27 |
| JP2003512127A (ja) | 2003-04-02 |
| DE60019949T2 (de) | 2006-04-27 |
| EP1221907B1 (en) | 2005-05-04 |
| JP4119124B2 (ja) | 2008-07-16 |
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