WO2001023523A3 - Secreted proteins and uses thereof - Google Patents

Secreted proteins and uses thereof Download PDF

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Publication number
WO2001023523A3
WO2001023523A3 PCT/US2000/027202 US0027202W WO0123523A3 WO 2001023523 A3 WO2001023523 A3 WO 2001023523A3 US 0027202 W US0027202 W US 0027202W WO 0123523 A3 WO0123523 A3 WO 0123523A3
Authority
WO
WIPO (PCT)
Prior art keywords
tango
nucleic acid
family members
transmembrane
polypeptide
Prior art date
Application number
PCT/US2000/027202
Other languages
French (fr)
Other versions
WO2001023523A2 (en
Inventor
Susan Kirst
Nicholas Wrighton
Christopher C Fraser
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Priority to AU11908/01A priority Critical patent/AU1190801A/en
Publication of WO2001023523A2 publication Critical patent/WO2001023523A2/en
Publication of WO2001023523A3 publication Critical patent/WO2001023523A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention provides isolated TANGO 315, TANGO 330, TANGO 437, and TANGO 480 nucleic acid molecules and polypeptide molecules. TANGO 315 family members encode transmembrane polypeptides related to CD33 and OB-BP-1. TANGO 330 family members encode transmembrane and secreted polypeptide related to roundabout. TANGO 437 family members encode a transmembrane polypeptide that contains an ion transport protein domain, a cell cycle protein domain and a putative permease domain. TANGO 480 family members encode a transmembrane polypeptide. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introdued or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
PCT/US2000/027202 1999-09-30 2000-10-02 Secreted proteins and uses thereof WO2001023523A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU11908/01A AU1190801A (en) 1999-09-30 2000-10-02 Secreted proteins and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40963499A 1999-09-30 1999-09-30
US09/409,634 1999-09-30

Publications (2)

Publication Number Publication Date
WO2001023523A2 WO2001023523A2 (en) 2001-04-05
WO2001023523A3 true WO2001023523A3 (en) 2001-10-04

Family

ID=23621344

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/027202 WO2001023523A2 (en) 1999-09-30 2000-10-02 Secreted proteins and uses thereof

Country Status (2)

Country Link
AU (1) AU1190801A (en)
WO (1) WO2001023523A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002036771A2 (en) 2000-11-06 2002-05-10 Cancer Research Technology Limited Imaging, diagnosis and treatment of disease
EP1434866A2 (en) * 2001-10-01 2004-07-07 Ucb, S.A. Genes associated with mast cell activation
EP1565491B1 (en) 2002-11-20 2010-03-31 Cancer Research Technology Limited Antibodies binding to human magic roundabout (mr), polypeptides and uses thereof for inhibition of angiogenesis
MX2009008430A (en) 2007-02-09 2009-10-28 Genentech Inc Anti-robo4 antibodies and uses therefor.
KR20210060670A (en) 2008-12-09 2021-05-26 제넨테크, 인크. Anti-pd-l1 antibodies and their use to enhance t-cell function

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6201105B1 (en) * 1989-09-05 2001-03-13 Craig A. Smith Tumor necrosis factor receptor polypeptides recombinant P75 (Type II)

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6201105B1 (en) * 1989-09-05 2001-03-13 Craig A. Smith Tumor necrosis factor receptor polypeptides recombinant P75 (Type II)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 1 January 1998 (1998-01-01), PATEL ET AL., XP002939131, Database accession no. AN015388 *
DATABASE GENBANK [online] 22 June 1999 (1999-06-22), YE ET AL.: "Human mRNA from cd34+ stem cells", XP002939130, Database accession no. AF150143 *

Also Published As

Publication number Publication date
AU1190801A (en) 2001-04-30
WO2001023523A2 (en) 2001-04-05

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