WO2000050442A3 - Secreted proteins and uses thereof - Google Patents

Secreted proteins and uses thereof Download PDF

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Publication number
WO2000050442A3
WO2000050442A3 PCT/US2000/004784 US0004784W WO0050442A3 WO 2000050442 A3 WO2000050442 A3 WO 2000050442A3 US 0004784 W US0004784 W US 0004784W WO 0050442 A3 WO0050442 A3 WO 0050442A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
expression vectors
tango
provides isolated
Prior art date
Application number
PCT/US2000/004784
Other languages
French (fr)
Other versions
WO2000050442A2 (en
Inventor
Sean A Mccarthy
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Priority to EP00915863A priority Critical patent/EP1159413A4/en
Priority to AU37066/00A priority patent/AU3706600A/en
Publication of WO2000050442A2 publication Critical patent/WO2000050442A2/en
Publication of WO2000050442A3 publication Critical patent/WO2000050442A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides isolated nucleic acid molecules, designated TANGO 201 and TANGO 223, which encode wholly secreted or membrane-associated proteins. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
PCT/US2000/004784 1999-02-26 2000-02-25 Secreted proteins and uses thereof WO2000050442A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP00915863A EP1159413A4 (en) 1999-02-26 2000-02-25 Secreted proteins and uses thereof
AU37066/00A AU3706600A (en) 1999-02-26 2000-02-25 Secreted proteins and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25938899A 1999-02-26 1999-02-26
US09/259,388 1999-02-26

Publications (2)

Publication Number Publication Date
WO2000050442A2 WO2000050442A2 (en) 2000-08-31
WO2000050442A3 true WO2000050442A3 (en) 2000-12-21

Family

ID=22984739

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/004784 WO2000050442A2 (en) 1999-02-26 2000-02-25 Secreted proteins and uses thereof

Country Status (3)

Country Link
EP (1) EP1159413A4 (en)
AU (1) AU3706600A (en)
WO (1) WO2000050442A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005019574B4 (en) * 2005-04-27 2009-07-30 Infineon Technologies Ag Contacting arrangement for a semiconductor device
CN102245640B (en) 2008-12-09 2014-12-31 霍夫曼-拉罗奇有限公司 Anti-PD-L1 antibodies and their use to enhance T-cell function

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2299256A1 (en) * 1997-08-04 1999-02-11 Millennium Biotherapeutics, Inc. Tango-72 and tango-77 nucleic acid molecules and polypeptides
JP2002537757A (en) * 1998-08-24 2002-11-12 アルファジーン・インコーポレイテッド Secreted proteins and polynucleotides encoding them
WO2000029448A2 (en) * 1998-11-17 2000-05-25 Sagami Chemical Research Center Human proteins having hydrophobic domains and dnas encoding these proteins

Non-Patent Citations (11)

* Cited by examiner, † Cited by third party
Title
ANAL. BIOCHEM.,, vol. 236, no. 1, 1996, pages 107 - 113, XP002931389 *
DATABASE GENBANK, 24 December 1997 (1997-12-24), MARRA M. ET AL.: "The WashU-HHMI Mouse EST Project", XP002931393 *
DATABASE GENBANK, 25 April 1996 (1996-04-25), HILLIER L. ET AL.: "The WashU-Merck EST project", XP002931398 *
DATABASE GENBANK, 25 January 1999 (1999-01-25), LEE N.H. ET AL.: "Rat Genome Project: Generation of rat EST (REST) Catalog & Rat gene index", XP002931394 *
DATABASE GENBANK, 7 January 1997 (1997-01-07), MARRA M. ET AL.: "The WashU-HHMI mouse EST project", XP002931395 *
DATABASE GENBANK, ANDERSSON B. ET AL.: "A "double adaptor" method for improved shotgun library construction", XP002931390 *
DATABASE GENBANK, HILLIER L. ET AL.: "Generation and analysis of 280,000 human expressed sequences tags", XP002931397 *
DATABASE GENBANK, YU W. ET AL.: "Large-scale concatenation cDNA sequencing", XP002931392 *
GENOME RES., vol. 6, 1996, pages 807 - 828, XP002931396 *
GENOME RES.,, vol. 7, no. 4, 1997, pages 353 - 358, XP002931391 *
See also references of EP1159413A4 *

Also Published As

Publication number Publication date
EP1159413A4 (en) 2005-12-14
AU3706600A (en) 2000-09-14
EP1159413A2 (en) 2001-12-05
WO2000050442A2 (en) 2000-08-31

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