WO2001017422A1 - Procede et appareil pour determiner des caracteristiques du sang, y compris l'hemoglobine - Google Patents

Procede et appareil pour determiner des caracteristiques du sang, y compris l'hemoglobine Download PDF

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Publication number
WO2001017422A1
WO2001017422A1 PCT/SE2000/001741 SE0001741W WO0117422A1 WO 2001017422 A1 WO2001017422 A1 WO 2001017422A1 SE 0001741 W SE0001741 W SE 0001741W WO 0117422 A1 WO0117422 A1 WO 0117422A1
Authority
WO
WIPO (PCT)
Prior art keywords
light
blood
vessel
light beam
blood cells
Prior art date
Application number
PCT/SE2000/001741
Other languages
English (en)
Inventor
Lars-Göran LINDBERG
Gunnar Enlund
Magnus Vegfors
Original Assignee
Optoq Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9903182A external-priority patent/SE516836C2/sv
Priority claimed from SE0001711A external-priority patent/SE516856C2/sv
Application filed by Optoq Ab filed Critical Optoq Ab
Priority to JP2001521219A priority Critical patent/JP2003508765A/ja
Priority to EP00963217A priority patent/EP1210009A1/fr
Priority to AU74665/00A priority patent/AU7466500A/en
Publication of WO2001017422A1 publication Critical patent/WO2001017422A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/681—Wristwatch-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14535—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring haematocrit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/411—Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6825—Hand
    • A61B5/6826—Finger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6838—Clamps or clips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
    • G01N21/532—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke with measurement of scattering and transmission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14557—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted to extracorporeal circuits

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Vascular Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

On détermine des caractéristiques du sang, y compris l'hémoglobine, de façon non invasive à partir d'un mélange de liquide et de globules sanguins, contenu dans un récipient perméable à la lumière, notamment à partir d'un vaisseau sanguin d'un humain, et ce au moyen de deux rayons lumineux de longueurs d'ondes différentes dirigés sur le vaisseau en question. On calcule ensuite un quotient des intensités détectées de la lumière réfléchie provenant des rayons lumineux. Les caractéristiques du sang sont déterminées par l'analyse dudit quotient.
PCT/SE2000/001741 1999-09-08 2000-09-07 Procede et appareil pour determiner des caracteristiques du sang, y compris l'hemoglobine WO2001017422A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2001521219A JP2003508765A (ja) 1999-09-08 2000-09-07 ヘモグロビンを含む血液特性を測定する方法及び装置
EP00963217A EP1210009A1 (fr) 1999-09-08 2000-09-07 Procede et appareil pour determiner des caracteristiques du sang, y compris l'hemoglobine
AU74665/00A AU7466500A (en) 1999-09-08 2000-09-07 Method and apparatus for detecting blood characteristics including hemoglobin

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9903182-5 1999-09-08
SE9903182A SE516836C2 (sv) 1999-09-08 1999-09-08 Metod och apparat för optisk bestämning av blodkarakterisktika
SE0001711A SE516856C2 (sv) 2000-05-09 2000-05-09 Metod och apparat för optisk bestämning av blodkarakteristika
SE0001711-1 2000-05-09

Publications (1)

Publication Number Publication Date
WO2001017422A1 true WO2001017422A1 (fr) 2001-03-15

Family

ID=26655101

Family Applications (3)

Application Number Title Priority Date Filing Date
PCT/SE2000/001740 WO2001017421A1 (fr) 1999-09-08 2000-09-07 Procede et appareil de mesure combinee de la saturation de l'hemoglobine et de l'oxygene
PCT/SE2000/001739 WO2001017420A1 (fr) 1999-09-08 2000-09-07 Procede et appareil de detection de caracteristiques du sang, notamment l'hemoglobine
PCT/SE2000/001741 WO2001017422A1 (fr) 1999-09-08 2000-09-07 Procede et appareil pour determiner des caracteristiques du sang, y compris l'hemoglobine

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PCT/SE2000/001740 WO2001017421A1 (fr) 1999-09-08 2000-09-07 Procede et appareil de mesure combinee de la saturation de l'hemoglobine et de l'oxygene
PCT/SE2000/001739 WO2001017420A1 (fr) 1999-09-08 2000-09-07 Procede et appareil de detection de caracteristiques du sang, notamment l'hemoglobine

Country Status (4)

Country Link
EP (3) EP1210007A1 (fr)
JP (3) JP2003508144A (fr)
AU (3) AU7466300A (fr)
WO (3) WO2001017421A1 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10223450A1 (de) * 2002-05-23 2003-12-04 Laser & Med Tech Gmbh Optisches Verfahren zur Bestimmung des extrazellulären Hämoglobingehaltes in Blutkonserven
JP2005513502A (ja) * 2001-12-28 2005-05-12 ヘモク アクチボラゲット 分析法及びそのための装置
US8728023B2 (en) 2006-07-27 2014-05-20 Fresenius Medical Care Holdings, Inc. Apparatus and methods for early stage peritonitis detection including self-cleaning effluent chamber
US8777891B2 (en) 2006-07-27 2014-07-15 Fresenius Medical Care Holdings, Inc. Apparatus and methods for early stage peritonitis detection and for in vivo testing of bodily fluid
US8801652B2 (en) 2006-07-27 2014-08-12 Fresenius Medical Care Holding, Inc. Early stage peritonitis detection apparatus and methods
CN108918473A (zh) * 2018-09-10 2018-11-30 广州益得智教育科技有限公司 透光度测量仪
US10863909B2 (en) 2014-05-02 2020-12-15 Respiheart Ab Device and system for determining physiological parameters from the sternum bone
CN113288136A (zh) * 2021-07-06 2021-08-24 山东大学齐鲁医院 人体组织血红蛋白浓度指数的无创检测装置和检测方法

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ITTO20010189A1 (it) 2001-03-02 2002-09-02 Gambro Dasco Spa Metodo per misurare la concentrazione di emoglobina nel sangue in un circuito di una macchina di dialisi, dispositivo di misura e circuito p
JP3760920B2 (ja) 2003-02-28 2006-03-29 株式会社デンソー センサ
US6992772B2 (en) * 2003-06-19 2006-01-31 Optix Lp Method and apparatus for optical sampling to reduce interfering variances
JP2005204869A (ja) * 2004-01-22 2005-08-04 Matsushita Electric Ind Co Ltd 歯茎観察装置
US7869850B2 (en) 2005-09-29 2011-01-11 Nellcor Puritan Bennett Llc Medical sensor for reducing motion artifacts and technique for using the same
JP4944093B2 (ja) * 2006-03-10 2012-05-30 川澄化学工業株式会社 血液特性計測プローブ、循環器系人工臓器及び人工肺
DE102006029899B4 (de) * 2006-06-29 2009-06-04 Fresenius Medical Care Deutschland Gmbh Spektroskopischer Detektor und Verfahren zur Bestimmung von Blut und biologischen Markersubstanzen in Flüssigkeiten
US8219170B2 (en) 2006-09-20 2012-07-10 Nellcor Puritan Bennett Llc System and method for practicing spectrophotometry using light emitting nanostructure devices
US7574245B2 (en) 2006-09-27 2009-08-11 Nellcor Puritan Bennett Llc Flexible medical sensor enclosure
US7684842B2 (en) 2006-09-29 2010-03-23 Nellcor Puritan Bennett Llc System and method for preventing sensor misuse
FR2912049A1 (fr) * 2007-02-06 2008-08-08 Univ Rennes I Etablissement Pu Dispositif de mesure d'au moins un parametre physiologique
US8280469B2 (en) 2007-03-09 2012-10-02 Nellcor Puritan Bennett Llc Method for detection of aberrant tissue spectra
US8265724B2 (en) 2007-03-09 2012-09-11 Nellcor Puritan Bennett Llc Cancellation of light shunting
US7806832B2 (en) * 2007-04-30 2010-10-05 The General Electric Company False positive reduction in SPO2 atrial fibrillation detection using average heart rate and NIBP
EP2142097B1 (fr) * 2007-05-02 2019-01-09 Sensitive Pty Ltd Mesure non invasive de la saturation en oxygène du sang
DE202007018570U1 (de) * 2007-11-09 2008-12-04 Envitec-Wismar Gmbh Vorrichtung zur Messung der Sauerstoffsättigung im Blut
RU2511278C2 (ru) * 2008-05-09 2014-04-10 Конинклейке Филипс Электроникс Н.В. Бесконтактное наблюдение дыхания у пациента и оптический датчик для измерения методом фотоплетизмографии
US9895068B2 (en) 2008-06-30 2018-02-20 Covidien Lp Pulse oximeter with wait-time indication
US8480581B2 (en) * 2009-03-24 2013-07-09 Cardiac Pacemakers, Inc. Systems and methods for anemia detection, monitoring, and treatment
US9002655B2 (en) 2010-05-03 2015-04-07 Gambro Lundia Ab Medical apparatus for extracorporeal blood treatment and method for determining a blood parameter value in a medical apparatus thereof
WO2012140559A1 (fr) 2011-04-11 2012-10-18 Medic4All Ag Mesure d'oxymétrie de pouls déclenchant une mesure d'ecg
JP5959814B2 (ja) 2011-08-08 2016-08-02 ソニー株式会社 血液分析装置および血液分析方法
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EP2994042B1 (fr) 2013-05-10 2023-09-27 University Of Utah Research Foundation Dispositifs, systèmes et procédés permettant de mesurer une perte de sang
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CN104224143B (zh) * 2014-09-28 2016-05-04 成都金海鼎盛科技有限公司 超低功耗的ppg信号采集电路及采集方法
FR3046048B1 (fr) * 2015-12-23 2020-03-27 Bioserenity Dispositif et procede pour la mesure de la concentration d'un compose present dans le sang
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JP6847788B2 (ja) * 2017-03-08 2021-03-24 京セラ株式会社 測定装置及び測定方法
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EP3752060A4 (fr) * 2018-02-17 2021-11-24 Trilinear BioVentures, LLC Système et méthode d'obtention de données de santé à, l'aide d'un réseau neuronal
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WO2020166091A1 (fr) * 2019-02-15 2020-08-20 俊徳 加藤 Dispositif de mesure de fonction biologique, procédé de mesure de fonction biologique et programme
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JP2023056972A (ja) * 2021-10-08 2023-04-20 日機装株式会社 血液浄化装置
WO2023119242A1 (fr) * 2021-12-23 2023-06-29 Scuola Superiore Di Studi Universitari E Di Perfezionamento Sant'anna Dispositif et procédé d'évaluation optique du niveau d'hémolyse dans un échantillon sanguin

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US5934277A (en) * 1991-09-03 1999-08-10 Datex-Ohmeda, Inc. System for pulse oximetry SpO2 determination

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US5934277A (en) * 1991-09-03 1999-08-10 Datex-Ohmeda, Inc. System for pulse oximetry SpO2 determination

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005513502A (ja) * 2001-12-28 2005-05-12 ヘモク アクチボラゲット 分析法及びそのための装置
DE10223450A1 (de) * 2002-05-23 2003-12-04 Laser & Med Tech Gmbh Optisches Verfahren zur Bestimmung des extrazellulären Hämoglobingehaltes in Blutkonserven
US8728023B2 (en) 2006-07-27 2014-05-20 Fresenius Medical Care Holdings, Inc. Apparatus and methods for early stage peritonitis detection including self-cleaning effluent chamber
US8777891B2 (en) 2006-07-27 2014-07-15 Fresenius Medical Care Holdings, Inc. Apparatus and methods for early stage peritonitis detection and for in vivo testing of bodily fluid
US8801652B2 (en) 2006-07-27 2014-08-12 Fresenius Medical Care Holding, Inc. Early stage peritonitis detection apparatus and methods
US10863909B2 (en) 2014-05-02 2020-12-15 Respiheart Ab Device and system for determining physiological parameters from the sternum bone
CN108918473A (zh) * 2018-09-10 2018-11-30 广州益得智教育科技有限公司 透光度测量仪
CN113288136A (zh) * 2021-07-06 2021-08-24 山东大学齐鲁医院 人体组织血红蛋白浓度指数的无创检测装置和检测方法
CN113288136B (zh) * 2021-07-06 2022-10-04 山东大学齐鲁医院 人体组织血红蛋白浓度指数的无创检测装置和检测方法

Also Published As

Publication number Publication date
JP2003508765A (ja) 2003-03-04
AU7466300A (en) 2001-04-10
WO2001017421A1 (fr) 2001-03-15
JP2003508144A (ja) 2003-03-04
EP1210009A1 (fr) 2002-06-05
EP1210007A1 (fr) 2002-06-05
EP1210008A1 (fr) 2002-06-05
AU7466400A (en) 2001-04-10
JP2003508143A (ja) 2003-03-04
WO2001017420A1 (fr) 2001-03-15
AU7466500A (en) 2001-04-10

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