WO2001012665A3 - Cytokine zalpha48 a enroulement en helice - Google Patents

Cytokine zalpha48 a enroulement en helice Download PDF

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Publication number
WO2001012665A3
WO2001012665A3 PCT/US2000/022714 US0022714W WO0112665A3 WO 2001012665 A3 WO2001012665 A3 WO 2001012665A3 US 0022714 W US0022714 W US 0022714W WO 0112665 A3 WO0112665 A3 WO 0112665A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
zalpha48
helical cytokine
cytokine
helical
Prior art date
Application number
PCT/US2000/022714
Other languages
English (en)
Other versions
WO2001012665A2 (fr
Inventor
Darrell C Conklin
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to JP2001517563A priority Critical patent/JP2003508032A/ja
Priority to AU69161/00A priority patent/AU6916100A/en
Priority to EP00957562A priority patent/EP1204681A2/fr
Priority to CA002381794A priority patent/CA2381794A1/fr
Publication of WO2001012665A2 publication Critical patent/WO2001012665A2/fr
Publication of WO2001012665A3 publication Critical patent/WO2001012665A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne des polypeptides cytokine, des matériaux et des procédés destinés à les produire, ainsi qu'une méthode d'utilisation. Ces polypeptides comprennent au moins neuf résidus d'acides aminés contigus de séquence SEQ ID NO:2, et peuvent être préparés comme polypeptides de fusion comprenant des séquences hétérologues, telles que des marqueurs d'affinité. Les polypeptides de l'invention et les polynucléotides codant pour eux peuvent être utilisés dans un large cadre d'applications concernant la thérapeutique, le diagnostic et la recherche.
PCT/US2000/022714 1999-08-18 2000-08-18 Cytokine zalpha48 a enroulement en helice WO2001012665A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2001517563A JP2003508032A (ja) 1999-08-18 2000-08-18 ヘリカルサイトカインｚａｌｐｈａ４８
AU69161/00A AU6916100A (en) 1999-08-18 2000-08-18 Helical cytokine zalpha48
EP00957562A EP1204681A2 (fr) 1999-08-18 2000-08-18 Cytokine zalpha48 a enroulement en helice
CA002381794A CA2381794A1 (fr) 1999-08-18 2000-08-18 Cytokine zalpha48 a enroulement en helice

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37682699A 1999-08-18 1999-08-18
US09/376,826 1999-08-18

Publications (2)

Publication Number Publication Date
WO2001012665A2 WO2001012665A2 (fr) 2001-02-22
WO2001012665A3 true WO2001012665A3 (fr) 2001-07-12

Family

ID=23486680

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/022714 WO2001012665A2 (fr) 1999-08-18 2000-08-18 Cytokine zalpha48 a enroulement en helice

Country Status (5)

Country Link
EP (1) EP1204681A2 (fr)
JP (1) JP2003508032A (fr)
AU (1) AU6916100A (fr)
CA (1) CA2381794A1 (fr)
WO (1) WO2001012665A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020168756A1 (en) 2001-03-23 2002-11-14 Fuji Photo Film Co., Ltd. Particle size variable reactor
US7077982B2 (en) 2001-03-23 2006-07-18 Fuji Photo Film Co., Ltd. Molecular electric wire, molecular electric wire circuit using the same and process for producing the molecular electric wire circuit
JP4294946B2 (ja) 2002-12-13 2009-07-15 富士フイルム株式会社 標的検出装置及び標的検出方法並びに標的検出用基材
US7076127B2 (en) 2003-01-14 2006-07-11 Fuji Photo Film Co., Ltd. Optical switch and safety apparatus using the same
US20050250184A1 (en) * 2003-11-26 2005-11-10 Sheppard Paul O Peptide hormones zalpha48 and zsig97

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063088A2 (fr) * 1998-06-02 1999-12-09 Genentech, Inc. Proteines membranaires et acides nucleiques codant ces proteines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063088A2 (fr) * 1998-06-02 1999-12-09 Genentech, Inc. Proteines membranaires et acides nucleiques codant ces proteines

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHAIKEN IRWIN M ET AL: "Identifying structure-function relationships in four-helix bundle cytokines: Towards de novo mimetics design.", TRENDS IN BIOTECHNOLOGY, vol. 14, no. 10, 1996, pages 369 - 375, XP004035727, ISSN: 0167-7799 *
DATABASE GENEMBL 30 July 1999 (1999-07-30), STRAUSBERG,R.: "ts84b03.x1 NCI_CGAP_GC6 Homo sapiens cDNA clone IMAGE:2237933 3', mRNA sequence", XP002158512 *

Also Published As

Publication number Publication date
EP1204681A2 (fr) 2002-05-15
AU6916100A (en) 2001-03-13
CA2381794A1 (fr) 2001-02-22
JP2003508032A (ja) 2003-03-04
WO2001012665A2 (fr) 2001-02-22

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