WO2001009178A3 - Human chaperone proteins - Google Patents

Human chaperone proteins Download PDF

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Publication number
WO2001009178A3
WO2001009178A3 PCT/US2000/021313 US0021313W WO0109178A3 WO 2001009178 A3 WO2001009178 A3 WO 2001009178A3 US 0021313 W US0021313 W US 0021313W WO 0109178 A3 WO0109178 A3 WO 0109178A3
Authority
WO
WIPO (PCT)
Prior art keywords
chaperone proteins
hcpn
human chaperone
provides
expression
Prior art date
Application number
PCT/US2000/021313
Other languages
French (fr)
Other versions
WO2001009178A2 (en
Inventor
Henry Yue
Olga Bandman
Y Tom Tang
Mariah R Baughn
Yalda Azimzai
Dyung Aina M Lu
Original Assignee
Incyte Genomics Inc
Henry Yue
Olga Bandman
Y Tom Tang
Mariah R Baughn
Yalda Azimzai
Dyung Aina M Lu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Henry Yue, Olga Bandman, Y Tom Tang, Mariah R Baughn, Yalda Azimzai, Dyung Aina M Lu filed Critical Incyte Genomics Inc
Priority to CA002374743A priority Critical patent/CA2374743A1/en
Priority to AU65187/00A priority patent/AU6518700A/en
Priority to EP00952500A priority patent/EP1203015A2/en
Priority to JP2001513984A priority patent/JP2003529327A/en
Publication of WO2001009178A2 publication Critical patent/WO2001009178A2/en
Publication of WO2001009178A3 publication Critical patent/WO2001009178A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides human chaperone proteins (HCPN) and polynucleotides which identify and encode HCPN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HCPN.
PCT/US2000/021313 1999-08-03 2000-08-03 Human chaperone proteins WO2001009178A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002374743A CA2374743A1 (en) 1999-08-03 2000-08-03 Human chaperone proteins
AU65187/00A AU6518700A (en) 1999-08-03 2000-08-03 Human chaperone proteins
EP00952500A EP1203015A2 (en) 1999-08-03 2000-08-03 Human chaperone proteins
JP2001513984A JP2003529327A (en) 1999-08-03 2000-08-03 Human chaperone protein

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US14690899P 1999-08-03 1999-08-03
US60/146,908 1999-08-03
US16092499P 1999-10-22 1999-10-22
US60/160,924 1999-10-22

Publications (2)

Publication Number Publication Date
WO2001009178A2 WO2001009178A2 (en) 2001-02-08
WO2001009178A3 true WO2001009178A3 (en) 2001-09-27

Family

ID=26844400

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/021313 WO2001009178A2 (en) 1999-08-03 2000-08-03 Human chaperone proteins

Country Status (5)

Country Link
EP (1) EP1203015A2 (en)
JP (1) JP2003529327A (en)
AU (1) AU6518700A (en)
CA (1) CA2374743A1 (en)
WO (1) WO2001009178A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646249A (en) * 1994-02-28 1997-07-08 The United States Of America As Represented By The Department Of Health And Human Services Isolation and characterization of a novel chaperone protein
WO1999047655A2 (en) * 1998-03-20 1999-09-23 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid fragments with heightened expression in normal breast tissue

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5646249A (en) * 1994-02-28 1997-07-08 The United States Of America As Represented By The Department Of Health And Human Services Isolation and characterization of a novel chaperone protein
WO1999047655A2 (en) * 1998-03-20 1999-09-23 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid fragments with heightened expression in normal breast tissue

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BIRD C: "Human DNA sequence from clone RP3-336M4 on chromosome 1p36.11-36.2", EMBL SEQUENCE DATABASE, 2 July 1999 (1999-07-02), HEIDELBERG DE, XP002157391 *
KRIEF ET AL.: "Identification and characterization of cvHsp", THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 51, 17 December 1999 (1999-12-17), pages 36592 - 36600, XP002157393 *
LIEW ET AL.: "B85F Heart Homo sapiens cDNA clone B855, mRNA sequence", EMBL SEQUENCE DATABASE, 20 December 1994 (1994-12-20), HEIDELBERG DE, XP002157392 *
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCE USA, vol. 91, 1994, pages 10645 - 10649 *

Also Published As

Publication number Publication date
JP2003529327A (en) 2003-10-07
WO2001009178A2 (en) 2001-02-08
AU6518700A (en) 2001-02-19
EP1203015A2 (en) 2002-05-08
CA2374743A1 (en) 2001-02-08

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