WO2001000188A3 - Tetrahydrochinolinyl-6-methyldihydrothiadiazinon-derivate ind ihre verwendung zur prophylaxe und/oder behandlung von anämien - Google Patents
Tetrahydrochinolinyl-6-methyldihydrothiadiazinon-derivate ind ihre verwendung zur prophylaxe und/oder behandlung von anämien Download PDFInfo
- Publication number
- WO2001000188A3 WO2001000188A3 PCT/EP2000/005571 EP0005571W WO0100188A3 WO 2001000188 A3 WO2001000188 A3 WO 2001000188A3 EP 0005571 W EP0005571 W EP 0005571W WO 0100188 A3 WO0100188 A3 WO 0100188A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tetrahydroquinolinyl
- methyldihydrothiadiazinone
- derivatives
- preventing
- treating anaemia
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Hematology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU61504/00A AU6150400A (en) | 1999-06-29 | 2000-06-16 | Tetrahydroquinolinyl-6-methyldihydrothiadiazinone derivatives and use thereof |
EP00947850A EP1196173A2 (de) | 1999-06-29 | 2000-06-16 | Tetrahydrochinolinyl-6-methyldihydrothiadiazinon-derivate und ihre verwendung zur prophylaxe und/oder behandlung von anämien |
JP2001505898A JP2003503345A (ja) | 1999-06-29 | 2000-06-16 | テトラヒドロキノリニル−6−メチルジヒドロチアジアジノン誘導体およびそれらの使用 |
CA002376891A CA2376891A1 (en) | 1999-06-29 | 2000-06-16 | Tetrahydroquinolinyl-6-methyldihydrothiadiazinone derivatives and use thereof |
US10/018,928 US6699857B1 (en) | 1999-06-29 | 2000-06-16 | Tetrahydroquinolinyl 6-methyldihydrothiadiazinone derivatives and use thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19929785.1 | 1999-06-29 | ||
DE19929785A DE19929785A1 (de) | 1999-06-29 | 1999-06-29 | Tetrahydrochinolinyl-6-methyldihydrothiadiazinon-Derivate und ihre Verwendung |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001000188A2 WO2001000188A2 (de) | 2001-01-04 |
WO2001000188A3 true WO2001000188A3 (de) | 2001-03-22 |
Family
ID=7912943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2000/005571 WO2001000188A2 (de) | 1999-06-29 | 2000-06-16 | Tetrahydrochinolinyl-6-methyldihydrothiadiazinon-derivate ind ihre verwendung zur prophylaxe und/oder behandlung von anämien |
Country Status (7)
Country | Link |
---|---|
US (1) | US6699857B1 (de) |
EP (1) | EP1196173A2 (de) |
JP (1) | JP2003503345A (de) |
AU (1) | AU6150400A (de) |
CA (1) | CA2376891A1 (de) |
DE (1) | DE19929785A1 (de) |
WO (1) | WO2001000188A2 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2462715T3 (es) * | 2008-12-19 | 2014-05-26 | Genentech, Inc. | Compuestos y métodos de uso |
US8940737B2 (en) | 2011-10-14 | 2015-01-27 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
US8889675B2 (en) | 2011-10-14 | 2014-11-18 | Abbvie Inc. | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4916128A (en) * | 1987-06-06 | 1990-04-10 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Thiadiazinones |
US4987121A (en) * | 1988-05-27 | 1991-01-22 | Center For Innovative Technology | Erythropoietic factor |
US5137885A (en) * | 1990-12-21 | 1992-08-11 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Thiadiazinones |
US5188828A (en) * | 1990-11-08 | 1993-02-23 | Brigham And Women's Hospital | Interleukin-6 to stimulate erythropoietin production |
US5206363A (en) * | 1991-09-02 | 1993-04-27 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Process for the resolution of enantiomers of 5-heteroaryl-1,3,4-thiadiazinones |
US5643938A (en) * | 1992-06-10 | 1997-07-01 | Fujisawa Pharmaceutical Co., Ltd. | Pyrazolopyridine compounds for the treatment of anemia |
DE19904391A1 (de) * | 1999-02-04 | 2000-08-10 | Bayer Ag | Pyrazol-Alkylamide |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4230755A1 (de) | 1992-09-14 | 1994-03-17 | Schering Ag | Verwendung von PDE-Inhibitoren bei der Behandlung von Nieren- und Ureter-Erkrankungen |
DE4338948A1 (de) | 1993-11-15 | 1995-05-18 | Carlen Judith | Verwendung von PDE-Inhibitoren bei der Behandlung erektiler Dysfunktionen |
DE19500558A1 (de) | 1995-01-11 | 1996-07-18 | Merck Patent Gmbh | 3-Alkoxycarbonyl-thiadiazinone |
-
1999
- 1999-06-29 DE DE19929785A patent/DE19929785A1/de not_active Withdrawn
-
2000
- 2000-06-16 US US10/018,928 patent/US6699857B1/en not_active Expired - Fee Related
- 2000-06-16 EP EP00947850A patent/EP1196173A2/de not_active Withdrawn
- 2000-06-16 WO PCT/EP2000/005571 patent/WO2001000188A2/de not_active Application Discontinuation
- 2000-06-16 AU AU61504/00A patent/AU6150400A/en not_active Abandoned
- 2000-06-16 CA CA002376891A patent/CA2376891A1/en not_active Abandoned
- 2000-06-16 JP JP2001505898A patent/JP2003503345A/ja active Pending
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4916128A (en) * | 1987-06-06 | 1990-04-10 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Thiadiazinones |
US4987121A (en) * | 1988-05-27 | 1991-01-22 | Center For Innovative Technology | Erythropoietic factor |
US5188828A (en) * | 1990-11-08 | 1993-02-23 | Brigham And Women's Hospital | Interleukin-6 to stimulate erythropoietin production |
US5137885A (en) * | 1990-12-21 | 1992-08-11 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Thiadiazinones |
US5206363A (en) * | 1991-09-02 | 1993-04-27 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Process for the resolution of enantiomers of 5-heteroaryl-1,3,4-thiadiazinones |
US5643938A (en) * | 1992-06-10 | 1997-07-01 | Fujisawa Pharmaceutical Co., Ltd. | Pyrazolopyridine compounds for the treatment of anemia |
DE19904391A1 (de) * | 1999-02-04 | 2000-08-10 | Bayer Ag | Pyrazol-Alkylamide |
Non-Patent Citations (2)
Title |
---|
SCHWINGER R H G ET AL: "Enantioselective Ca-2+-sensitizing effects of EMD 53998, EMD 57033 and EMD 57439 in human myocardium.", EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, vol. 24, no. SUPPL. 2, 1994, 28th Annual Scientific Meeting of the European Society for Clinical Investigation;Toledo, Spain; April 20-23, 1994, pages A5, XP000972326, ISSN: 0014-2972 * |
WAUGH WILLIAM H ET AL: "Evidence that L-arginine is a key amino acid in sickle cell anemia - A preliminary report.", NUTRITION RESEARCH, vol. 19, no. 4, April 1999 (1999-04-01), pages 501 - 518, XP000972387, ISSN: 0271-5317 * |
Also Published As
Publication number | Publication date |
---|---|
EP1196173A2 (de) | 2002-04-17 |
CA2376891A1 (en) | 2001-01-04 |
AU6150400A (en) | 2001-01-31 |
DE19929785A1 (de) | 2001-01-04 |
US6699857B1 (en) | 2004-03-02 |
JP2003503345A (ja) | 2003-01-28 |
WO2001000188A2 (de) | 2001-01-04 |
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