WO2000076664A1 - Porteur d'echantillon - Google Patents

Porteur d'echantillon Download PDF

Info

Publication number
WO2000076664A1
WO2000076664A1 PCT/GB2000/002366 GB0002366W WO0076664A1 WO 2000076664 A1 WO2000076664 A1 WO 2000076664A1 GB 0002366 W GB0002366 W GB 0002366W WO 0076664 A1 WO0076664 A1 WO 0076664A1
Authority
WO
WIPO (PCT)
Prior art keywords
sample
sample holder
section
patches
receiving section
Prior art date
Application number
PCT/GB2000/002366
Other languages
English (en)
Inventor
Jose Antonio Lorente-Acosta
Miguel Lorente Acosta
Original Assignee
Universidad De Granada
Whatman International Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad De Granada, Whatman International Ltd. filed Critical Universidad De Granada
Priority to AU55479/00A priority Critical patent/AU5547900A/en
Publication of WO2000076664A1 publication Critical patent/WO2000076664A1/fr

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above
    • B01L3/5055Hinged, e.g. opposable surfaces
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0096Casings for storing test samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N2001/002Devices for supplying or distributing samples to an analysing apparatus
    • G01N2001/005Packages for mailing or similar transport of samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N2001/002Devices for supplying or distributing samples to an analysing apparatus
    • G01N2001/007Devices specially adapted for forensic samples, e.g. tamper-proofing, sample tracking

Definitions

  • the present invention relates to a sample holder and in particular to a sample holder suitable for use in the storage of small volumes of biological specimens such a blood.
  • sample holder is described specifically intended for home use with blood samples that are to be sent for HIV testing.
  • the sample holder consists of a carton with a pocket in which an elongate glass tube is located.
  • a person pricks their finger and introduces blood into the glass tube which is then sealed at each end using a clay-like substance which is provided.
  • the sealed glass tube is then placed in the pocket in the carton and covered with a flap which is secured to the body of the carton using adhesive tape.
  • the closed carton is placed within a plastic bag and separately labelled and then the carton and the plastic bag are placed within an envelope so that the carton, with the sample inside, can be mailed to a testing laboratory.
  • sample holders can be found in EP0473190, EP0734684 and
  • filter paper has been used in the collection and storage of small quantities of biological samples.
  • the filter paper is usually attached to an elongate strip of paper that can be folded about the filter paper and on which details such as the name of the person from which the sample was taken can be printed.
  • the filter paper absorbs the fluid sample, the filter paper renders the sample immobile thereby avoiding the need for costly and bulky glass vials or test tubes.
  • samples of hair and nails may be immobilised in a similar sample holder by providing an adhesive surface on the strip of paper, instead of a filer paper, to which the hair sample is adhered.
  • filter paper may be used, such as that described in US5976572, which is treated with a preservative.
  • the sample holder is placed within a separate envelope which also bears details of the sample and/or an addressee.
  • sample holders employing filter papers avoid the disadvantages of bulky and costly glass vials or test tubes which can be prone to breakage, such sample holders present their own problems.
  • sample holders that employ filter paper are prone to contamination which is of particular importance if the sample holders are to be used by forensics at the crime scenes.
  • sample holder is stored in a separate envelope there is the risk that, in error, the labelling on the envelope may not match the details of the sample inside.
  • the present invention provides an improved sample holder that seeks to overcome the problems identified above with existing sample holders and in particular prevents contamination of samples and the reduces the risks of mislabelling of samples.
  • the present invention provides a sample holder suitable for use in the storage of biological or mineral samples, the sample holder comprising a main body having a sample receiving section with one or more patches of absorbent material disposed thereon; a first cover section foldable about a first fold line over the sample receiving section; and sealing means disposed so as to form a sealed enclosure between the sample receiving section and the cover section about the one or more patches of absorbent material.
  • sample holder that as a single entity is able to receive a biological or mineral sample and contain the sample in a sealed enclosure which is suitable for use in the mail or for long term storage of samples.
  • sample holder may include regions for private and public data to be displayed. Such data may be in the form of sample identification, barcodes, custody chain, sample source data such as patient identification or identification of the location of the sample source as well as postal information such as sender and addressee.
  • the sealing means is an adhesive which may be disposed as a pair of opposed lines of adhesive extending away from the first fold line so as to form a pair of continuous seals either side of the patches of absorbent material.
  • the adhesive may be disposed in a continuous line of adhesive extending substantially parallel to the free edges of the first cover sheet.
  • a second cover section may be provided which is foldable about a second fold line to at least partly cover the first cover section.
  • the first and second cover sections will lie on opposing sides of the sample receiving section and further sealing means may be provided to secure the second cover section to the first cover section.
  • the sample receiving section includes a plurality of patches of absorbent material and the first cover section is divided into a plurality of individual flaps whereby the sealing means is disposed so as to form separate sealed enclosures between the sample receiving section and each of the flaps of the cover section about one or more patches of absorbent material.
  • the one or more patches of absorbent material are filter paper which may or may not be treated with a preservative.
  • the present invention provides a sample holder suitable for use in the storage of biological or mineral samples, the sample holder comprising a main body having a sample receiving section; a first cover section foldable about a first fold line over the sample receiving section; and sealing means disposed so as to form a sealed enclosure between the sample receiving section and the cover section within which a biological or mineral sample may be contained.
  • the sample holder may include sample holding means in the form, for example, of an adhesive strip for immobilising the sample in the sample holder.
  • Figure 1 is a plan view of a first embodiment of a sample holder in accordance with the present invention
  • Figure 2 is a perspective view of the sample holder of Figure 1 in a partially folded state
  • Figure 3 is plan view of the sample holder of Figure 1 from the other side;
  • Figure 4 is a plan view of a second embodiment of a sample holder in accordance with the present invention
  • Figure 5 is a perspective view of the sample holder of Figure 4 in a partially folded state
  • Figure 6 is a perspective view of a third embodiment of a sample holder in accordance with the present invention.
  • Figure 7 illustrates a fourth embodiment of a sample holder in accordance with the present invention.
  • Figure 8 illustrates a fifth embodiment of a sample holder is accordance with the present invention.
  • the sample holder shown in Figure 1 generally comprises a main body in the form of an elongate supporting strip 2 to which is attached one or more sample absorbent patches 3.
  • the elongate strip 2 is preferably made of paper, card or a plastics material onto which sample data may be printed, stamped, written or adhered using adhesive labels.
  • the elongate strip 2 has two approximately equidistant fold lines 4 so that the elongate strip 2 is divided into three sections and can be folded with the outer edge sections 5, 6 folding over the central or sample receiving section 7.
  • the absorbent patches 3 are preferably made from a filter paper such as BFC180, 3MM or 31 ET (Whatman International Ltd. graded filter paper) or FTA (Whatman International Ltd) which is an example of a filter paper specifically treated to lyse cells and preserve the released nucleic acids.
  • the patches are suited to the deposit of samples either by means of instruments such as syringes and pipettes or by direct contact for example with a finger or a plant stem, for example.
  • the patches 3 may be coloured so that once a sample has been applied to a patch it is clearly visible as a result in a change in the colour of the patch.
  • the patches 3 are attached to the central section 7 of the elongate strip 2 and are positioned so as to be separate from one another.
  • each of the patches 3 is attached to the elongate strip 2 along one edge 8 by means of adhesive, for example, or alternatively through mechanical securement using staples, for example.
  • Each patch 3 is attached to the elongate strip 2 in such a way that the main body 9 of the patch is free of the elongate strip and is able to absorb a fluid biological sample applied to it, such as blood.
  • the elongate strip may comprise filter paper and the patches are an extension to the elongate strip which is folded in on itself in a concertina or spiral arrangement.
  • Self-adhesive tape 10 is arranged along the peripheral edges of the outer sections 5, 6 of the elongate strip.
  • the self-adhesive tape 10 extends along the opposing free ends of the elongate strip and at least partly along each side edge of the elongate strip 2 up to the fold lines 4.
  • the self-adhesive tape 10 adheres to the elongate strip and has a removable protective covering of a release material over its upper adhesive surface.
  • adhesives such as a pressure sensitive adhesive or a heat activated adhesive may be deployed about the edges of the elongate strip.
  • the adhesive 10 provided along the edges of the elongate strip 2 is preferably continuous about the peripheral edges of the outer sections 5, 6.
  • the adhesive 10 may additionally extend along the edges of the central section 7 of the elongate strip and either side of the fold lines 4.
  • the adhesive may be omitted from the free transverse edge of the first edge section and instead two opposing substantially parallel lines of adhesive tape may be provided which follow the longitudinal edges of the first edge section. It will, of course, be apparent that the adhesive tape need not follow the edges of the outer edge section.
  • the adhesive tape is required only to provide a sealed enclosure between the central section and the first edge section.
  • the sealing to the enclosure may be direct between the central section and the first edge section or indirect as a result of adhesion between the first and second edge sections.
  • sealing means other than adhesive may be used to generate the sealed enclosure for the sample such as a mechanical securement mechanism such as edge grippers or clips.
  • a biological specimen such as blood or animal or plant tissue such as tree sap is applied to an absorbent patch 3 and allowed to dry.
  • data on the sample is added to the second edge section 6 of the elongate strip.
  • the edge section 6 may be pre-printed to identify the data required such as name, date of sample collection etc. Additionally, or in the alternative, the edge section 6 may include a space 11 where a label bearing an identification barcode may be adhered.
  • the adhesive strip 10 on the edges of the first edge section thus adheres to the periphery of the central section 7 surrounding the absorbent patches.
  • the absorbent patches with the biological samples are wholly enclosed by the folded line of the first edge section 5 with the central section 7 and by the continuous adhesion of the adhesive strip 10 to the edges of both the edge section and the central section.
  • the second edge section 6 is folded about its fold line so as to cover the back of the first edge section 5 and the self-adhesive strip 10 about the peripheral edges of the second edge section 6 adheres to the exposed back of the first edge section.
  • the sample data applied to the second edge section 6 is protected from the sample applied to the patch 3 but is also hidden and so personal information such a patient details can be kept private.
  • the order of the folding of the sections of the sample holder is more clearly illustrated in Figure 2.
  • the sample holder once folded, is a third of its original size.
  • the samples on the absorbent patches are wholly contained and protected against external contamination within a space enclosed along all sides either by means of the fold line between different sections of the strip or by means of the adhesion of the self-adhesive strip to the edges of the three sections of the strip.
  • a permanent adhesive is used as the self-adhesive strip 10
  • the sample holder will be able to provide evidence of any tampering as any attempt to open the sample holder should tear or damage the elongate strip 2.
  • a permanent adhesive may be used in combination with a resealable adhesive so that the sample holder is capable of providing evidence of tampering but also permits the sample holder to be re-sealed after opening, where necessary.
  • Suitable adhesives include a water-based adhesive such as a pva adhesive or an acrylic copolymer pressure sensitive adhesive.
  • the back of the sample holder may be used to print information such as a custody chain for the sample so that the provenance of the sample can be traced.
  • the same identification code label may be adhered to the back of the sample holder so that the contents of the sample holder can be identified without the need to open the sample holder.
  • the sample holder acts as its own, integral envelope and so postal details can be added to the back of the sample holder when it is intended that the sample be mailed to a laboratory or clinic.
  • the elongate strip 2 may be provided with a water protective cover on its back surface so that when the sample holder is folded, the holder is protected from the ingress or seepage of water or other fluid contaminants.
  • FIG 4 an alternative sample holder is illustrated.
  • the sample holders of Figures 1 and 4 are similar and so like elements have been identified using the same reference numerals.
  • the sample holder of Figure 4 is particularly suited for clinical use and is intended for use where a plurality of different tests are to be performed on a plurality of samples taken from the same patient.
  • the sample holder comprises an elongate strip of card 2 that is divided by fold lines 4 into three sections 5, 6, 7.
  • the second edge section 6 is identical to that shown in Figure 1 and provides space for information to be printed or attached regarding the patient.
  • the central section 7 has a series of four absorbent patches 3 arranged in a line transversely across the central section. Each patch 3 has deliminated on it two separate regions so that each patch defines a row 12 of two separate samples. Adjacent each row 12 is printed identification of a clinical department for which the samples are intended or the type of test to be performed on the samples provided on the patch in that row.
  • the first edge section 5 has three cuts 13 extending substantially parallel to one another and to the longitudinal edges of the strip 2.
  • the cuts 13 extend the entire length of the first edge section 5 and are aligned with the edges of the rows 12 of the central section 7.
  • the cuts 13 divide the first edge section into four independently foldable flaps 14. Lines of pressure-sensitive adhesive 15 are provided along the edges of each flap 14 and along the peripheral edges of the second edge section 6.
  • each of the patches having samples on which tests have been completed can be isolated from the remaining samples by folding and sealing the corresponding flap around the patch. Once all of the tests have been completed, four separate sealed spaces remain with a single patch within each space.
  • the second edge section may be folded over each of the folded flaps to seal around the outermost edges of the flaps to provide a double seal to each of the samples.
  • identification data may be provided on the back of the sample holder along with any mailing information, if relevant.
  • individual patches may be pre-treated with different preparatory substances in dependence on the tests to be carried out on the samples on each patch.
  • individual patches may be of different material depending upon the test to be performed.
  • four rows of patches are shown with two sample regions on each patch, the number of sample regions and the number of rows can vary as desired.
  • a single absorbent patch of material is provided in the central section having an array of 8 x 12 sample regions deliminated on the patch. This arrangement is particularly suited to use with automated test apparatus.
  • FIG. 6 a third embodiment of a sample holder is illustrated.
  • the sample holder in Figure 6 is similar to those of figures 1 and 4 except that the central section 7 does not have any absorbent patches.
  • the central section may be bare or may include a strip of pressure-sensitive adhesive.
  • the edge sections 5, 6 of the elongate strip 2 are the same as for the sample holder shown in Figure 1 .
  • non-fluid samples such as hair and nail samples may be collected and stored.
  • the hair samples may be placed loose on the central section 7 before being encased by the first edge section folding over the hair and sealing along the edges of the section or the hair samples may be adhered to the pressure sensitive adhesive provided in the central section before the first edge section 5 is folded over to seal around the edges of the central section 7.
  • This sample holder is suitable for use both in forensic sciences and in dermatology and tricology.
  • Figures 7 and 8 further alternative versions of the sample holder are illustrated.
  • the main body of the sample holder consists of only a sample receiving section 7 and a cover section 5 which are joined along a foldline 4.
  • Figure 8 a more complex arrangement is illustrated in which the main body has a central section 7, first and second opposing cover sections and a further side cover section 17 which folds over the first cover section 5 to seal one of the longitudinal edges of the central section and is sandwiched between the first and second cover sections.
  • sample holders described above are robust and provide reliable protection from contamination and a tamper-evident construction. It will, of course, be apparent that the size and shape of the sample holders is in no way restricted to the particular sizes and shapes illustrated in the accompanying figures.
  • the sample holders are suitable for use in forensic sciences such as in the compilation of DNA databases including human identification trials and population studies, in paternity testing, DNA identification of babies and particularly in sample collection at crime scenes where the avoidance of cross-contamination is essential.
  • the sample holders are also suitable for use in clinical medicine such as genetics diagnosis and epidemiology as well as anthropology and animal genetics. Although reference herein has focused on human biology it will be apparent that the sample holder is equally suited to use in animal and vegetable biological analysis and mineral analysis.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne un porteur d'échantillon constitué d'une bande (2) allongée que l'on peut plier en trois. La section centrale (7) possède une ou plusieurs pièces (3) de matériau absorbant sur lesquelles on peut stocker des échantillons biologiques. Les bords périphériques de cette bande allongée sont pourvus d'un adhésif (10) de sorte que lorsque l'échantillon est placé sur la pièce (3), on puisse plier cette bande allongée, enfermant ainsi cet échantillon à l'abri des impuretés.
PCT/GB2000/002366 1999-06-16 2000-06-15 Porteur d'echantillon WO2000076664A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU55479/00A AU5547900A (en) 1999-06-16 2000-06-15 Sample holder

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES9901340A ES2163356B1 (es) 1999-06-16 1999-06-16 Equipo autonomo para recogida, almacenamiento y envio de muestras bio logicas humanas, animales y vegetales.
ESP9901340 1999-06-16

Publications (1)

Publication Number Publication Date
WO2000076664A1 true WO2000076664A1 (fr) 2000-12-21

Family

ID=8308866

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/002366 WO2000076664A1 (fr) 1999-06-16 2000-06-15 Porteur d'echantillon

Country Status (3)

Country Link
AU (1) AU5547900A (fr)
ES (1) ES2163356B1 (fr)
WO (1) WO2000076664A1 (fr)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1177769A2 (fr) * 2000-08-03 2002-02-06 H.M. The Queen in Right of Canada as repr. by The Solicitor Gen. act.through The Commissioner of Royal Canadian Mounted Police Kit de collecte de racines de cheveux
WO2003050507A1 (fr) * 2001-12-12 2003-06-19 The Secretary Of State For Defence Dispositif d'echantillonnage
EP1392173B1 (fr) * 2001-05-31 2006-02-08 EnviteC-Wismar GmbH Dispositif permettant de collecter des echantillons liquides
WO2006038023A1 (fr) 2004-10-07 2006-04-13 Forensic Alliance Limited Bande de prelevement d'echantillon et procede pour le prelevement d'echantillons medico-legaux sur des surfaces
SG125998A1 (en) * 2005-03-24 2006-10-30 King Car Food Ind Co Ltd Noninvasive device for collecting bio-specimens
EP1932480A1 (fr) * 2006-12-15 2008-06-18 Bio Optica-Milano S.p.A. Élément de support pour biopsie et kit pour la collecte et le traitement de biopsies comprenant ce support
US7435601B2 (en) 2003-02-19 2008-10-14 Fitzco Incorporated Biological specimen handling method
DE102008062807A1 (de) * 2007-12-29 2009-07-09 Nuctech Co. Ltd. Wischprobenahmeanordnung
WO2011089300A3 (fr) * 2010-01-20 2011-10-20 Universidad Del País Vasco Dispositif pour la traçabilité dans des prélèvements d'échantillons biologiques et procédé de traçage de ces derniers
GB2482036A (en) * 2010-10-12 2012-01-18 Nammonic Holding Ltd Flexible sample retainer opens to provide access to sample
WO2013119729A1 (fr) * 2012-02-10 2013-08-15 Sekisui Diagnostics, Llc Dispositifs, procédés et kits de collecte et de transport d'échantillons
US8900856B2 (en) 2004-04-08 2014-12-02 Biomatrica, Inc. Integration of sample storage and sample management for life science
ITMI20131354A1 (it) * 2013-08-07 2015-02-08 Copan Italia Spa Supporto per la conservazione di campioni di materiale biologico e relativo metodo di produzione
US9376709B2 (en) 2010-07-26 2016-06-28 Biomatrica, Inc. Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures
WO2016156155A1 (fr) * 2015-03-31 2016-10-06 Ge Healthcare Uk Limited Améliorations dans et se rapportant à des collecteurs d'échantillon biologique et la manipulation de ce dernier
US9725703B2 (en) 2012-12-20 2017-08-08 Biomatrica, Inc. Formulations and methods for stabilizing PCR reagents
US9845489B2 (en) 2010-07-26 2017-12-19 Biomatrica, Inc. Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
US10064404B2 (en) 2014-06-10 2018-09-04 Biomatrica, Inc. Stabilization of thrombocytes at ambient temperatures
WO2019153035A1 (fr) * 2018-02-09 2019-08-15 Chymica Research International Pty Ltd Dispositif d'échantillonnage, procédé et système
US10568317B2 (en) 2015-12-08 2020-02-25 Biomatrica, Inc. Reduction of erythrocyte sedimentation rate

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ES2296492B1 (es) * 2005-12-12 2009-05-07 Jose Evaristo Fernandez Ruiz Tablilla porta tejidos.

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US5783759A (en) * 1995-06-24 1998-07-21 Boehringer Mannheim Gmbh Element and system for collecting, transporting and storing sample material to be analyzed

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GB1585127A (en) * 1976-04-28 1981-02-25 Smithkline Corp Specimen test slide
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US5273888A (en) * 1984-01-16 1993-12-28 Helena Laboratories Corporation Chemical test kit and method for determining the presence of blood in a specimen and for verifying the effectiveness of the chemicals
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Cited By (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1177769A3 (fr) * 2000-08-03 2003-06-25 H.M. The Queen in Right of Canada as repr. by The Solicitor Gen. act.through The Commissioner of Royal Canadian Mounted Police Kit de collecte de racines de cheveux
EP1177769A2 (fr) * 2000-08-03 2002-02-06 H.M. The Queen in Right of Canada as repr. by The Solicitor Gen. act.through The Commissioner of Royal Canadian Mounted Police Kit de collecte de racines de cheveux
AU784968B2 (en) * 2000-08-03 2006-08-10 Her Majesty The Queen In Right Of Canada As Represented By The Solicitor General Acting Through The Commissioner Of The Royal Canadian Mounted Police Hair root collection kit
EP1392173B1 (fr) * 2001-05-31 2006-02-08 EnviteC-Wismar GmbH Dispositif permettant de collecter des echantillons liquides
AU2002313476B2 (en) * 2001-05-31 2006-05-18 Envitec-Wismar Gmbh Device for collecting liquid samples
WO2003050507A1 (fr) * 2001-12-12 2003-06-19 The Secretary Of State For Defence Dispositif d'echantillonnage
AU2002350948B2 (en) * 2001-12-12 2006-06-15 The Secretary Of State For Defence Sampling device
US7435601B2 (en) 2003-02-19 2008-10-14 Fitzco Incorporated Biological specimen handling method
US8900856B2 (en) 2004-04-08 2014-12-02 Biomatrica, Inc. Integration of sample storage and sample management for life science
US9078426B2 (en) 2004-04-08 2015-07-14 Biomatrica, Inc. Integration of sample storage and sample management for life science
WO2006038023A1 (fr) 2004-10-07 2006-04-13 Forensic Alliance Limited Bande de prelevement d'echantillon et procede pour le prelevement d'echantillons medico-legaux sur des surfaces
SG125998A1 (en) * 2005-03-24 2006-10-30 King Car Food Ind Co Ltd Noninvasive device for collecting bio-specimens
EP1932480A1 (fr) * 2006-12-15 2008-06-18 Bio Optica-Milano S.p.A. Élément de support pour biopsie et kit pour la collecte et le traitement de biopsies comprenant ce support
DE102008062807A1 (de) * 2007-12-29 2009-07-09 Nuctech Co. Ltd. Wischprobenahmeanordnung
DE102008062807B4 (de) * 2007-12-29 2011-03-24 Nuctech Co. Ltd. Wischprobenahmeanordnung und deren Verwendung
US8042414B2 (en) 2007-12-29 2011-10-25 Nuctech Company Limited Wipe sampling assembly
WO2011089300A3 (fr) * 2010-01-20 2011-10-20 Universidad Del País Vasco Dispositif pour la traçabilité dans des prélèvements d'échantillons biologiques et procédé de traçage de ces derniers
ES2373288A1 (es) * 2010-01-20 2012-02-02 Universidad Del Pais Vasco Dispositivo para la trazabilidad en tomas de muestras biológicas y procedimiento de trazado de las mismas.
US9999217B2 (en) 2010-07-26 2018-06-19 Biomatrica, Inc. Compositions for stabilizing DNA, RNA, and proteins in blood and other biological samples during shipping and storage at ambient temperatures
US9845489B2 (en) 2010-07-26 2017-12-19 Biomatrica, Inc. Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures
US9376709B2 (en) 2010-07-26 2016-06-28 Biomatrica, Inc. Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures
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