WO2000070099A3 - Expression genique differente dans des regions specifiques du cerveau, dans des maladies neurodegeneratives - Google Patents
Expression genique differente dans des regions specifiques du cerveau, dans des maladies neurodegeneratives Download PDFInfo
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- WO2000070099A3 WO2000070099A3 PCT/US2000/013951 US0013951W WO0070099A3 WO 2000070099 A3 WO2000070099 A3 WO 2000070099A3 US 0013951 W US0013951 W US 0013951W WO 0070099 A3 WO0070099 A3 WO 0070099A3
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002371212A CA2371212A1 (fr) | 1999-05-19 | 2000-05-19 | Expression genique differente dans des regions specifiques du cerveau, dans des maladies neurodegeneratives |
AU51503/00A AU5150300A (en) | 1999-05-19 | 2000-05-19 | Differential gene expression in specific regions of the brain in neurodegenerative diseases |
EP00936142A EP1208228A2 (fr) | 1999-05-19 | 2000-05-19 | Expression genique differente dans des regions specifiques du cerveau, dans des maladies neurodegeneratives |
JP2000618504A JP2003504007A (ja) | 1999-05-19 | 2000-05-19 | 神経変性性疾患における脳の特異的な領域での異なる遺伝子発現 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13479099P | 1999-05-19 | 1999-05-19 | |
US60/134,790 | 1999-05-19 | ||
US57461300A | 2000-05-18 | 2000-05-18 | |
US09/574,613 | 2000-05-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000070099A2 WO2000070099A2 (fr) | 2000-11-23 |
WO2000070099A3 true WO2000070099A3 (fr) | 2002-04-04 |
Family
ID=26832668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/013951 WO2000070099A2 (fr) | 1999-05-19 | 2000-05-19 | Expression genique differente dans des regions specifiques du cerveau, dans des maladies neurodegeneratives |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1208228A2 (fr) |
JP (1) | JP2003504007A (fr) |
AU (1) | AU5150300A (fr) |
CA (1) | CA2371212A1 (fr) |
WO (1) | WO2000070099A2 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001069261A2 (fr) * | 2000-03-15 | 2001-09-20 | Oxford Glycosciences (Uk) Ltd. | Proteines, genes et leur utilisation dans le diagnostic et le traitement de la demence vasculaire |
WO2002040996A2 (fr) * | 2000-11-08 | 2002-05-23 | Mitokor | Expression genetique differentielle dans des regions specifiques du cerveau dans les maladies neurodegeneratives |
WO2002067764A2 (fr) | 2001-02-27 | 2002-09-06 | Blanchette Rockefeller Neurosciences Institute | Diagnostic de la maladie d'alzheimer base sur la phosphorylation d'une proteine kinase activee par mitogene |
WO2003023056A2 (fr) * | 2001-09-12 | 2003-03-20 | F. Hoffmann-La Roche Ag | Marqueurs specifiques a la sclerose en plaques |
AU2003224120A1 (en) * | 2002-04-24 | 2003-11-10 | Evotec Neurosciences Gmbh | Diagnostic and therapeutic use of ensadin-0477 gene and protein for neurodegenerative diseases |
WO2004066823A2 (fr) * | 2003-01-30 | 2004-08-12 | Research Development Foundation | Procedes et compositions d'analyse de l'expression genique liee a la mitochondrie |
JP2008520203A (ja) * | 2004-11-15 | 2008-06-19 | ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート | アルツハイマー病の診断および治療のためのホスファターゼ2a(pp2a)の異常 |
US20090029873A1 (en) | 2005-10-11 | 2009-01-29 | Blanchette Rockefeller Neurosciences Institute | Alzheimer's Disease-Specific Alterations of the Erk1/Erk2 Phosphorylation Ratio-Alzheimer's Disease-Specific Molecular Biomarkers (Adsmb) |
JPWO2009020058A1 (ja) * | 2007-08-03 | 2010-11-04 | 学校法人慶應義塾 | 脱髄病変へのドラッグデリバリーシステム及び脱髄病変の生化学的マーカー |
US8163800B2 (en) | 2008-07-28 | 2012-04-24 | Blanchette Rockefeller Neurosciences Institute | PKC-activating compounds for the treatment of neurodegenerative diseases |
US8822166B2 (en) | 2008-07-28 | 2014-09-02 | Blanchette Rockefeller Neurosciences Institute | Stimulus-elicited genomic profile markers of alzheimer's disease |
JP6058395B2 (ja) | 2009-10-02 | 2017-01-11 | ブランシェット・ロックフェラー・ニューロサイエンスィズ・インスティテュート | アルツハイマー病の診断のための繊維芽細胞成長パターン |
WO2013071281A1 (fr) | 2011-11-13 | 2013-05-16 | Blanchette Rockefeller Neurosciences Institute | Esters de dcpla et méthodes de traitement les utilisant |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1995035373A2 (fr) * | 1994-06-10 | 1995-12-28 | La Jolla Cancer Research Foundation | Molecules d'acide nucleique codant la contactine humaine |
WO1997015690A1 (fr) * | 1995-10-24 | 1997-05-01 | Curagen Corporation | Procede et dispositif d'identification, de classification ou de denombrement de sequences d'adn dans un echantillon sans sequençage |
US5739289A (en) * | 1993-03-26 | 1998-04-14 | Becton, Dickinson And Company | Monoclonal antibody to human cell adhesion molecule |
WO1998049342A1 (fr) * | 1997-04-30 | 1998-11-05 | Forskningsparken I Ås As | Procede servant a preparer un type standard de produit de transcription genetique de diagnostic |
US5888498A (en) * | 1995-03-03 | 1999-03-30 | Mitokor | Cellular and animal models for diseases associated with mitochondrial defects |
-
2000
- 2000-05-19 EP EP00936142A patent/EP1208228A2/fr not_active Withdrawn
- 2000-05-19 WO PCT/US2000/013951 patent/WO2000070099A2/fr not_active Application Discontinuation
- 2000-05-19 AU AU51503/00A patent/AU5150300A/en not_active Abandoned
- 2000-05-19 JP JP2000618504A patent/JP2003504007A/ja not_active Withdrawn
- 2000-05-19 CA CA002371212A patent/CA2371212A1/fr not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5739289A (en) * | 1993-03-26 | 1998-04-14 | Becton, Dickinson And Company | Monoclonal antibody to human cell adhesion molecule |
WO1995035373A2 (fr) * | 1994-06-10 | 1995-12-28 | La Jolla Cancer Research Foundation | Molecules d'acide nucleique codant la contactine humaine |
US5888498A (en) * | 1995-03-03 | 1999-03-30 | Mitokor | Cellular and animal models for diseases associated with mitochondrial defects |
WO1997015690A1 (fr) * | 1995-10-24 | 1997-05-01 | Curagen Corporation | Procede et dispositif d'identification, de classification ou de denombrement de sequences d'adn dans un echantillon sans sequençage |
WO1998049342A1 (fr) * | 1997-04-30 | 1998-11-05 | Forskningsparken I Ås As | Procede servant a preparer un type standard de produit de transcription genetique de diagnostic |
Non-Patent Citations (2)
Title |
---|
PLAGGE A ET AL: "The gene of the neural cell recognition molecule F11: conserved exon-intron arrangement in genes of neural members of the immunoglobulin superfamily", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 192, no. 2, 1997, pages 215 - 225, XP004081714, ISSN: 0378-1119 * |
SHIMAZAKI K ET AL: "Age-related decline of f3/contactin in rat hippocampus", NEUROSCIENCE LETTERS, vol. 245, no. 2, 1998, pages 117 - 20, XP001024403 * |
Also Published As
Publication number | Publication date |
---|---|
CA2371212A1 (fr) | 2000-11-23 |
EP1208228A2 (fr) | 2002-05-29 |
JP2003504007A (ja) | 2003-02-04 |
WO2000070099A2 (fr) | 2000-11-23 |
AU5150300A (en) | 2000-12-05 |
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