WO2000064584A3 - Method and device for applying small quantities of liquid - Google Patents

Method and device for applying small quantities of liquid Download PDF

Info

Publication number
WO2000064584A3
WO2000064584A3 PCT/EP2000/003497 EP0003497W WO0064584A3 WO 2000064584 A3 WO2000064584 A3 WO 2000064584A3 EP 0003497 W EP0003497 W EP 0003497W WO 0064584 A3 WO0064584 A3 WO 0064584A3
Authority
WO
WIPO (PCT)
Prior art keywords
liquid
small quantities
applying small
supply line
impulse
Prior art date
Application number
PCT/EP2000/003497
Other languages
German (de)
French (fr)
Other versions
WO2000064584A2 (en
Inventor
Heinz Eipel
Stefan Emig
Siegfried Hauer
Walter Weishaar
Original Assignee
Basf Ag
Heinz Eipel
Stefan Emig
Siegfried Hauer
Walter Weishaar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag, Heinz Eipel, Stefan Emig, Siegfried Hauer, Walter Weishaar filed Critical Basf Ag
Priority to EP00929378A priority Critical patent/EP1173279B1/en
Priority to DK00929378T priority patent/DK1173279T3/en
Priority to AT00929378T priority patent/ATE249884T1/en
Priority to DE50003731T priority patent/DE50003731D1/en
Priority to US09/959,379 priority patent/US6599755B1/en
Priority to CA002371198A priority patent/CA2371198C/en
Priority to JP2000613568A priority patent/JP2002542499A/en
Publication of WO2000064584A2 publication Critical patent/WO2000064584A2/en
Publication of WO2000064584A3 publication Critical patent/WO2000064584A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B41—PRINTING; LINING MACHINES; TYPEWRITERS; STAMPS
    • B41J—TYPEWRITERS; SELECTIVE PRINTING MECHANISMS, i.e. MECHANISMS PRINTING OTHERWISE THAN FROM A FORME; CORRECTION OF TYPOGRAPHICAL ERRORS
    • B41J2/00—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed
    • B41J2/005—Typewriters or selective printing mechanisms characterised by the printing or marking process for which they are designed characterised by bringing liquid or particles selectively into contact with a printing material
    • B41J2/01—Ink jet
    • B41J2/17—Ink jet characterised by ink handling
    • B41J2/175—Ink supply systems ; Circuit parts therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00364—Pipettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00657—One-dimensional arrays
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

The invention relates to a method for applying small quantities of liquid to a substrate (13) using a pipette tip (1), which is connected to a flexible supply line (2). An increase in volume is produced in the supply line (2) in order to draw up a quantity of liquid, which is then discharged by creating an impulse on the supply line, this impulse being transmitted to the quantity of liquid located therein.
PCT/EP2000/003497 1999-04-27 2000-04-18 Method and device for applying small quantities of liquid WO2000064584A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
EP00929378A EP1173279B1 (en) 1999-04-27 2000-04-18 Method and device for applying small quantities of liquid
DK00929378T DK1173279T3 (en) 1999-04-27 2000-04-18 Method and apparatus for applying small amounts of liquid
AT00929378T ATE249884T1 (en) 1999-04-27 2000-04-18 METHOD AND DEVICE FOR APPLYING SMALL QUANTITIES OF LIQUID
DE50003731T DE50003731D1 (en) 1999-04-27 2000-04-18 METHOD AND DEVICE FOR APPLYING SMALL LIQUID AMOUNTS
US09/959,379 US6599755B1 (en) 1999-04-27 2000-04-18 Method and device for applying small quantities of liquid
CA002371198A CA2371198C (en) 1999-04-27 2000-04-18 Method and device for applying small quantities of liquid
JP2000613568A JP2002542499A (en) 1999-04-27 2000-04-18 Method and apparatus for depositing small amounts of liquid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19919135.2 1999-04-27
DE19919135A DE19919135A1 (en) 1999-04-27 1999-04-27 Method and device for applying small amounts of liquid

Publications (2)

Publication Number Publication Date
WO2000064584A2 WO2000064584A2 (en) 2000-11-02
WO2000064584A3 true WO2000064584A3 (en) 2001-03-29

Family

ID=7906044

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/003497 WO2000064584A2 (en) 1999-04-27 2000-04-18 Method and device for applying small quantities of liquid

Country Status (9)

Country Link
US (1) US6599755B1 (en)
EP (1) EP1173279B1 (en)
JP (1) JP2002542499A (en)
CN (1) CN1198689C (en)
AT (1) ATE249884T1 (en)
CA (1) CA2371198C (en)
DE (2) DE19919135A1 (en)
DK (1) DK1173279T3 (en)
WO (1) WO2000064584A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030054543A1 (en) * 1997-06-16 2003-03-20 Lafferty William Michael Device for moving a selected station of a holding plate to a predetermined location for interaction with a probe
WO2002040160A1 (en) * 2000-11-17 2002-05-23 Tecan Trading Ag Device and method for separating samples from a liquid
EP1252930A1 (en) 2001-04-27 2002-10-30 Tecan Trading AG Spray head
CN1311913C (en) * 2004-10-28 2007-04-25 博奥生物有限公司 Trace amount liquid jet system
DE102005002525A1 (en) * 2005-01-19 2006-07-27 Zengerle, Roland, Prof. Dr. Pipette tip, pipetting device, pipette tip actuator and method for nL pipetting
WO2006092942A1 (en) * 2005-03-02 2006-09-08 Nippon Sheet Glass Company, Limited Pipette tip
GB0607427D0 (en) * 2006-04-13 2006-05-24 Imi Vision Ltd Fluid dispenser
US20090104078A1 (en) * 2007-10-18 2009-04-23 Matrix Technologies Corporation Apparatus and method for dispensing small volume liquid samples
CH700417A1 (en) * 2009-02-13 2010-08-13 Leo Buehler Process control, valve assembly and portioning for portioning a flowable, pressurized mass.
JP5861298B2 (en) * 2010-09-03 2016-02-16 セイコーエプソン株式会社 Liquid supply apparatus and liquid ejection system
CN101987302A (en) * 2010-10-21 2011-03-23 孔兵 Quick multifunctional liquid operation device
CN103429348B (en) 2011-01-21 2016-03-09 拜奥－多特公司 There is the piezo dispenser of longitudinal converter and replaceable capillary
CN103990503B (en) * 2014-05-16 2015-09-09 临沂大学 Disposable liquid-transfering gun coating gun head and using method thereof
DE102014217358A1 (en) 2014-08-29 2016-03-03 Leo Bühler Portioning unit for portioning of flowable masses or powder, arrangement with several such portioning units and method for portioning of flowable masses or powder
WO2016078339A1 (en) 2014-11-17 2016-05-26 中国科学院微生物研究所 Apparatus, system, and method for generating micro liquid droplets and single-cell/single-molecule analysis apparatus
CN105032717B (en) * 2015-09-18 2017-10-17 京东方科技集团股份有限公司 A kind of sealant coating nozzles and frame enclosing gum coating apparatus
TWI636244B (en) * 2017-03-24 2018-09-21 國立清華大學 Manufacturing device and manufacturing method for test strips

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2086394A1 (en) * 1969-02-05 1971-12-31 Medinova Ab
DE3113345A1 (en) * 1981-04-02 1982-10-28 Conloc GmbH chemisch-technische Produkte, 8000 München Metering valve for viscous fluids
US5763278A (en) * 1995-11-01 1998-06-09 Tecan Ag Automated pipetting of small volumes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3786683A (en) * 1972-09-12 1974-01-22 Alphamedics Mfg Corp Hand-operated pipette
JPS49127207A (en) * 1973-04-10 1974-12-05
US4130394A (en) * 1977-10-03 1978-12-19 Technicon Instruments Corporation Short sample detection
US4195526A (en) * 1978-02-09 1980-04-01 Corning Glass Works Hand-held pipetter
US4140020A (en) * 1978-03-24 1979-02-20 Syva Company Seal-free pipette device
EP0028478B1 (en) * 1979-10-31 1985-02-20 The University Of Birmingham Improvements in or relating to pipette means
US5947167A (en) * 1992-05-11 1999-09-07 Cytologix Corporation Dispensing assembly with interchangeable cartridge pumps

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2086394A1 (en) * 1969-02-05 1971-12-31 Medinova Ab
DE3113345A1 (en) * 1981-04-02 1982-10-28 Conloc GmbH chemisch-technische Produkte, 8000 München Metering valve for viscous fluids
US5763278A (en) * 1995-11-01 1998-06-09 Tecan Ag Automated pipetting of small volumes

Also Published As

Publication number Publication date
ATE249884T1 (en) 2003-10-15
JP2002542499A (en) 2002-12-10
WO2000064584A2 (en) 2000-11-02
CN1373687A (en) 2002-10-09
US6599755B1 (en) 2003-07-29
EP1173279A2 (en) 2002-01-23
CA2371198C (en) 2008-01-08
DE50003731D1 (en) 2003-10-23
EP1173279B1 (en) 2003-09-17
DE19919135A1 (en) 2000-11-02
DK1173279T3 (en) 2004-01-19
CN1198689C (en) 2005-04-27
CA2371198A1 (en) 2000-11-02

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