WO2000061182A3 - Techniques et compositions pour le traitement et la prevention des maladies pulmonaires - Google Patents

Techniques et compositions pour le traitement et la prevention des maladies pulmonaires Download PDF

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Publication number
WO2000061182A3
WO2000061182A3 PCT/US2000/009494 US0009494W WO0061182A3 WO 2000061182 A3 WO2000061182 A3 WO 2000061182A3 US 0009494 W US0009494 W US 0009494W WO 0061182 A3 WO0061182 A3 WO 0061182A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
methods
compositions
prevention
lung disease
Prior art date
Application number
PCT/US2000/009494
Other languages
English (en)
Other versions
WO2000061182A2 (fr
Inventor
Roshantha A Chandraratna
Donald Massaro
Gloria Decarlo Massaro
Original Assignee
Allergan Sales Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Sales Inc filed Critical Allergan Sales Inc
Priority to AU42224/00A priority Critical patent/AU4222400A/en
Publication of WO2000061182A2 publication Critical patent/WO2000061182A2/fr
Publication of WO2000061182A3 publication Critical patent/WO2000061182A3/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne des techniques et des compositions destinées au traitement des maladies pulmonaires telles que l'emphysème et/ou la dysplasie broncho-pulmonaire chez les mammifères. L'invention concerne également des techniques et des compositions favorisant la formation de septa alvéolaires et augmentant la surface d'échange gazeux d'un poumon de mammifère, destinées à la prévention et/ou au traitement de la destruction alvéolaire.
PCT/US2000/009494 1999-04-14 2000-04-11 Techniques et compositions pour le traitement et la prevention des maladies pulmonaires WO2000061182A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU42224/00A AU4222400A (en) 1999-04-14 2000-04-11 Methods and compositions for the treatment and prevention of lung disease

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12921499P 1999-04-14 1999-04-14
US60/129,214 1999-04-14

Publications (2)

Publication Number Publication Date
WO2000061182A2 WO2000061182A2 (fr) 2000-10-19
WO2000061182A3 true WO2000061182A3 (fr) 2001-03-29

Family

ID=22438926

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/009494 WO2000061182A2 (fr) 1999-04-14 2000-04-11 Techniques et compositions pour le traitement et la prevention des maladies pulmonaires

Country Status (2)

Country Link
AU (1) AU4222400A (fr)
WO (1) WO2000061182A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2178B1 (en) 1999-10-19 2003-04-23 اف . هوفمان لاروش ايه جي Treatment of invasive diseases, using selected anti-PAR materials

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0286364A2 (fr) * 1987-04-06 1988-10-12 Riker Laboratories, Inc. Di-t-butylphénols substitués
WO1997019062A1 (fr) * 1995-11-22 1997-05-29 Allergan Arylamides ou heteroarylamides substitues ayant une activite biologique analogue a celle des retinoides
WO1997019052A1 (fr) * 1995-11-22 1997-05-29 Allergan Arylamides ou hetero-arylamides de tetrahydronaphtalene, de chromane, de thiochromane et d'acides carboxyliques 1,2,3,4-tetrahydroquinoliniques ayant une activite biologique de type retinoide
WO1998019999A1 (fr) * 1996-11-05 1998-05-14 Allergan Sales, Inc. Ligands tetrahydroquinolines, a substitution n-aryle, de recepteurs retinoides, possedant une activite du type agoniste, antagoniste ou agoniste inverse
US5919970A (en) * 1997-04-24 1999-07-06 Allergan Sales, Inc. Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0286364A2 (fr) * 1987-04-06 1988-10-12 Riker Laboratories, Inc. Di-t-butylphénols substitués
WO1997019062A1 (fr) * 1995-11-22 1997-05-29 Allergan Arylamides ou heteroarylamides substitues ayant une activite biologique analogue a celle des retinoides
WO1997019052A1 (fr) * 1995-11-22 1997-05-29 Allergan Arylamides ou hetero-arylamides de tetrahydronaphtalene, de chromane, de thiochromane et d'acides carboxyliques 1,2,3,4-tetrahydroquinoliniques ayant une activite biologique de type retinoide
WO1998019999A1 (fr) * 1996-11-05 1998-05-14 Allergan Sales, Inc. Ligands tetrahydroquinolines, a substitution n-aryle, de recepteurs retinoides, possedant une activite du type agoniste, antagoniste ou agoniste inverse
US5919970A (en) * 1997-04-24 1999-07-06 Allergan Sales, Inc. Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHYTIL F: "The lungs and vitamin A.", AMERICAN JOURNAL OF PHYSIOLOGY, (1992 MAY) 262 (5 PT 1) L517-27, XP000978073 *
TENG M ET AL: "IDENTIFICATION OF A RETINOIC ACID RECEPTOR ALPHA SUBTYPE SPECIFIC AGONIST", JOURNAL OF MEDICINAL CHEMISTRY,US,AMERICAN CHEMICAL SOCIETY. WASHINGTON, vol. 39, no. 16, 2 August 1996 (1996-08-02), pages 3035 - 3038, XP000652115, ISSN: 0022-2623 *

Also Published As

Publication number Publication date
WO2000061182A2 (fr) 2000-10-19
AU4222400A (en) 2000-11-14

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