WO2000055626A1 - Optical assay device and method - Google Patents

Optical assay device and method Download PDF

Info

Publication number
WO2000055626A1
WO2000055626A1 PCT/US2000/005837 US0005837W WO0055626A1 WO 2000055626 A1 WO2000055626 A1 WO 2000055626A1 US 0005837 W US0005837 W US 0005837W WO 0055626 A1 WO0055626 A1 WO 0055626A1
Authority
WO
WIPO (PCT)
Prior art keywords
optically active
active test
base
assay device
absorbent material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/005837
Other languages
English (en)
French (fr)
Inventor
James E. Maynard
Mark A. Crosby
Alan J. Fujii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inverness Medical Biostar Inc
Original Assignee
Thermo Biostar Inc
Biostar Inc USA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thermo Biostar Inc, Biostar Inc USA filed Critical Thermo Biostar Inc
Priority to CA002366307A priority Critical patent/CA2366307A1/en
Priority to AU37271/00A priority patent/AU772685B2/en
Priority to JP2000605207A priority patent/JP2002539452A/ja
Priority to EP00916114A priority patent/EP1166115A4/en
Priority to HK02104875.0A priority patent/HK1043831A1/zh
Publication of WO2000055626A1 publication Critical patent/WO2000055626A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/808—Optical sensing apparatus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/805—Optical property

Definitions

  • optical assay devices require that the user apply a discrete volume of sample (approximately 25 - 30 ⁇ L, ) on the surface and that the incubation times be controlled by user intervention.
  • Sample incubates on the surface in a static mode as the surface is solid and impermeable.
  • the drying process also requires user interaction to bring the adsorbent material into contact with the solid optical test surface from above the test surface .
  • the solid surface optical assays are extremely sensitive, an improvement in sensitivity can be gained by using all of the available sample (dependent on sample processing but generally greater than 200 ⁇ L) . In many testing sites, the requirement for user intervention in timing and drying the optical test device is inconvenient and not cost effective.
  • a front portion 28 of the base 12 includes an incurved cut-out 66.
  • the frame 20 also includes a recessed area 67 behind the incurved cut-out 66.
  • the recessed area 67 includes a ramp 68 extending from a bottom surface 69.
  • the recessed area 67 communicates with the outer well 34.
  • the film materials that may be used for the base optical material include, but are not limited to, amorphous silicon, polycrystalline silicon, lead telluride, titanium, germanium, cobalt, gallium, tellurium, iron oxide, or chromium, or the like.
  • amorphous silicon film having a thickness between 1000 and 5000 A is preferably used as the base optical material.
  • the applied sample flows across and through the layers of the optical stack 18 when the optical stack 18 does not contact the absorbent material, unaffected by the absorbent material 16, but at a much lower rate compared to when the optical stack 18 contacts the absorbent material 16.
  • Surface tension of the fluid in contact with the optical stack may also delay flow through the optical layer.
  • the device of the present invention allows the sample incubation to occur over a period of time to improve capture efficiency and also minimizes the user intervention required to complete the assay.
  • the device provides an increase in assay performance by allowing all available sample to flow across the optical member and through channels within the optical member. Because the contact time of sample with the test surface is controlled, the device is less sensitive to variable flow rates than other prior art devices. Also, in the device of the present invention, the signal generation is inherent in the composition and construction of the flow through support .

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PCT/US2000/005837 1999-03-18 2000-03-06 Optical assay device and method Ceased WO2000055626A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002366307A CA2366307A1 (en) 1999-03-18 2000-03-06 Optical assay device and method
AU37271/00A AU772685B2 (en) 1999-03-18 2000-03-06 Optical assay device and method
JP2000605207A JP2002539452A (ja) 1999-03-18 2000-03-06 光学アッセイ装置及び方法
EP00916114A EP1166115A4 (en) 1999-03-18 2000-03-06 OPTICAL TEST ARRANGEMENT AND METHOD
HK02104875.0A HK1043831A1 (zh) 1999-03-18 2000-03-06 光學測試儀器及其方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/272,641 US6287783B1 (en) 1999-03-18 1999-03-18 Optical assay device and method
US09/272,641 1999-03-18

Publications (1)

Publication Number Publication Date
WO2000055626A1 true WO2000055626A1 (en) 2000-09-21

Family

ID=23040667

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/005837 Ceased WO2000055626A1 (en) 1999-03-18 2000-03-06 Optical assay device and method

Country Status (10)

Country Link
US (2) US6287783B1 (enExample)
EP (1) EP1166115A4 (enExample)
JP (1) JP2002539452A (enExample)
KR (1) KR100674525B1 (enExample)
CN (1) CN100403029C (enExample)
AU (1) AU772685B2 (enExample)
CA (1) CA2366307A1 (enExample)
HK (1) HK1043831A1 (enExample)
TW (1) TW468048B (enExample)
WO (1) WO2000055626A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005512090A (ja) * 2001-12-12 2005-04-28 プロテオム システムズ インテレクチュアル プロパティ プロプライエタリー リミテッド 診断検査方法
EP1419387A4 (en) * 2001-08-20 2005-12-14 Proteome Systems Intellectual DIAGNOSTIC TEST METHOD AND APPARATUS
GB2474306A (en) * 2009-10-12 2011-04-13 Bioproducts Ltd Methods and device for detecting an analyte
WO2018019768A1 (en) * 2016-07-25 2018-02-01 Gentian As Assay device and method for assessing blood cells

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7640083B2 (en) 2002-11-22 2009-12-29 Monroe David A Record and playback system for aircraft
FR2792333B1 (fr) * 1999-04-14 2003-01-24 Labonord Dispositif de depot de cellules sur une plaque d'analyse
KR100675698B1 (ko) * 1999-08-06 2007-02-01 써모 바이오스타, 인크. 완전한 샘플 처리 능력을 포함하는 자동화된 진료 검출 시스템
AU2001278750A1 (en) * 2000-09-06 2002-03-22 Toyo Kohan Co. Ltd. Solid supports having surface-treated layer formed thereon
US20040241876A1 (en) * 2000-12-22 2004-12-02 France Fannes Flow through assay device, diagnostic kit comprising said assay device and use of said assay device in the detection of an analyte present in a sample
US20030013185A1 (en) * 2001-06-21 2003-01-16 Ravi Saraf Electro-optical detection device
US20040166593A1 (en) * 2001-06-22 2004-08-26 Nolte David D. Adaptive interferometric multi-analyte high-speed biosensor
AU2002300223B2 (en) * 2001-08-13 2008-12-11 Bayer Corporation Mechanical Mechanism for a Blood Glucose Sensor Dispensing Instrument
AU2002351164A1 (en) * 2001-11-26 2003-06-10 Molecular Reflections, Inc. Microscale immobilization of molecules using a hydrogel and methods of use thereof
US7098041B2 (en) 2001-12-11 2006-08-29 Kimberly-Clark Worldwide, Inc. Methods to view and analyze the results from diffraction-based diagnostics
AU2002350271B2 (en) * 2001-12-12 2008-07-31 Proteome Systems Ltd Diagnostic testing process
US8367013B2 (en) 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US20040018973A1 (en) * 2002-01-25 2004-01-29 University Of Pittsburgh Nuclear matrix protein alterations associated with colon cancer and colon metastasis to the liver, and uses thereof
US7485453B2 (en) 2002-05-03 2009-02-03 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7223368B2 (en) 2002-05-03 2007-05-29 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7118855B2 (en) 2002-05-03 2006-10-10 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7771922B2 (en) 2002-05-03 2010-08-10 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic device
US7214530B2 (en) 2002-05-03 2007-05-08 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic devices and method for producing biomolecule diagnostic devices
US7223534B2 (en) 2002-05-03 2007-05-29 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7091049B2 (en) 2002-06-26 2006-08-15 Kimberly-Clark Worldwide, Inc. Enhanced diffraction-based biosensor devices
JP3860130B2 (ja) * 2002-08-21 2006-12-20 東洋鋼鈑株式会社 固体支持体及び該固体支持体上に固定化された複数の物質又は複合体を脱離／イオン化することにより質量分析する方法
EP1531934B1 (en) * 2002-08-26 2013-04-24 Lattec I/S A testing device for testing or analysing fluids and a holder and a storage container for such devices
US20040156747A1 (en) * 2002-08-26 2004-08-12 Lattec I/S Testing device for testing or analysing fluids and a holder and a storage container for such devices
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7314763B2 (en) 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
US7432105B2 (en) 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7169550B2 (en) 2002-09-26 2007-01-30 Kimberly-Clark Worldwide, Inc. Diffraction-based diagnostic devices
US7247500B2 (en) 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7522762B2 (en) * 2003-04-16 2009-04-21 Inverness Medical-Biostar, Inc. Detection, resolution, and identification of arrayed elements
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7796266B2 (en) 2004-04-30 2010-09-14 Kimberly-Clark Worldwide, Inc. Optical detection system using electromagnetic radiation to detect presence or quantity of analyte
US7815854B2 (en) 2004-04-30 2010-10-19 Kimberly-Clark Worldwide, Inc. Electroluminescent illumination source for optical detection systems
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
EP1655606B1 (en) * 2004-11-05 2011-08-10 F. Hoffmann-La Roche AG Biochemical assay and device
US7663092B2 (en) 2005-02-01 2010-02-16 Purdue Research Foundation Method and apparatus for phase contrast quadrature interferometric detection of an immunoassay
US7910356B2 (en) 2005-02-01 2011-03-22 Purdue Research Foundation Multiplexed biological analyzer planar array apparatus and methods
US20070023643A1 (en) 2005-02-01 2007-02-01 Nolte David D Differentially encoded biological analyzer planar array apparatus and methods
DE102006027969A1 (de) * 2006-06-17 2007-12-20 X-Fab Semiconductor Foundries Ag Verfahren zur selektiven Entspiegelung einer Halbleitergrenzfläche durch eine besondere Prozessführung
KR100749903B1 (ko) 2006-09-21 2007-08-21 김경수 편광기
US7522282B2 (en) 2006-11-30 2009-04-21 Purdue Research Foundation Molecular interferometric imaging process and apparatus
WO2008089495A2 (en) 2007-01-19 2008-07-24 Purdue Research Foundation System with extended range of molecular sensing through integrated multi-modal data acquisition
WO2008118934A1 (en) 2007-03-26 2008-10-02 Purdue Research Foundation Method and apparatus for conjugate quadrature interferometric detection of an immunoassay
JP5124652B2 (ja) * 2007-10-23 2013-01-23 ベクトン・ディキンソン・アンド・カンパニー 分子および病理診断のための組織安定化用容器システム
US20100075863A1 (en) * 2008-09-25 2010-03-25 Northrop Grumman Systems Corporation Rotary array module for multiplexing spot-based optical readouts
US8012770B2 (en) 2009-07-31 2011-09-06 Invisible Sentinel, Inc. Device for detection of antigens and uses thereof
WO2011044574A1 (en) 2009-10-09 2011-04-14 Invisible Sentinel Device for detection of antigens and uses thereof
AU2012211141B2 (en) 2011-01-27 2016-11-03 Invisible Sentinel, Inc. Analyte detection devices, multiplex and tabletop devices for detection of analytes, and uses thereof
CA2866379C (en) 2012-03-09 2020-10-13 Invisible Sentinel, Inc. Methods and compositions for detecting multiple analytes with a single signal
WO2014176306A1 (en) 2013-04-23 2014-10-30 Montecito Bio Sciences Ltd Flow through testing system with pressure indicator
JP6600861B2 (ja) * 2015-04-08 2019-11-06 株式会社パートナーファーム 固相反応チップ及びこれを用いた測定方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137691A (en) * 1987-01-27 1992-08-11 V-Tech, Inc. Antibody testing system with removable air gap

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4246339A (en) 1978-11-01 1981-01-20 Millipore Corporation Test device
US4632901A (en) 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
DE3585780D1 (de) 1984-12-24 1992-05-07 Abbott Lab Analytische vorrichtung und verfahren zu ihrer verwendung.
US4623461A (en) 1985-05-31 1986-11-18 Murex Corporation Transverse flow diagnostic device
US4693834A (en) 1986-05-05 1987-09-15 Murex Corporation Transverse flow diagnostic kit
TW203120B (enExample) 1985-10-04 1993-04-01 Abbott Lab
US5160701A (en) 1986-02-18 1992-11-03 Abbott Laboratories Solid-phase analytical device and method for using same
US4789526A (en) 1986-12-15 1988-12-06 Pall Corporation Vacuum diagnostic device
US4976926A (en) 1986-12-15 1990-12-11 Pall Corporation Vacuum diagnostic device
US4797260A (en) * 1987-01-27 1989-01-10 V-Tech, Inc. Antibody testing system
US5006309A (en) 1988-04-22 1991-04-09 Abbott Laboratories Immunoassay device with liquid transfer between wells by washing
US4963325A (en) 1988-05-06 1990-10-16 Hygeia Sciences, Inc. Swab expressor immunoassay device
CA2035595A1 (en) 1990-04-12 1991-10-13 Carol A. Miller Immunoassay test device with thread control element
DE69103420T2 (de) * 1990-06-15 1994-12-01 Chiron Corp Selbstständige testanordnung.
US5212065A (en) 1990-10-25 1993-05-18 International Diagnostic Systems, Corp. Rapid assay device
US5418136A (en) 1991-10-01 1995-05-23 Biostar, Inc. Devices for detection of an analyte based upon light interference
CN1034975C (zh) * 1992-01-17 1997-05-21 四川省医学科学院寄生虫病防治研究所 一种检测血吸虫循环抗原的药盒

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137691A (en) * 1987-01-27 1992-08-11 V-Tech, Inc. Antibody testing system with removable air gap

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1419387A4 (en) * 2001-08-20 2005-12-14 Proteome Systems Intellectual DIAGNOSTIC TEST METHOD AND APPARATUS
US7205159B2 (en) 2001-08-20 2007-04-17 Proteome Systems Intellectual Property Pty Ltd. Diagnostic testing process and apparatus
JP2005512090A (ja) * 2001-12-12 2005-04-28 プロテオム システムズ インテレクチュアル プロパティ プロプライエタリー リミテッド 診断検査方法
US7875435B2 (en) 2001-12-12 2011-01-25 Proteome Systems Ltd Diagnostic testing process
US8067246B2 (en) 2001-12-12 2011-11-29 Tyrian Diagnostics Limited Diagnostic testing process
GB2474306A (en) * 2009-10-12 2011-04-13 Bioproducts Ltd Methods and device for detecting an analyte
WO2018019768A1 (en) * 2016-07-25 2018-02-01 Gentian As Assay device and method for assessing blood cells

Also Published As

Publication number Publication date
KR100674525B1 (ko) 2007-01-26
EP1166115A4 (en) 2006-09-20
HK1043831A1 (zh) 2002-09-27
CN1343311A (zh) 2002-04-03
TW468048B (en) 2001-12-11
JP2002539452A (ja) 2002-11-19
AU772685B2 (en) 2004-05-06
KR20020021777A (ko) 2002-03-22
AU3727100A (en) 2000-10-04
CN100403029C (zh) 2008-07-16
CA2366307A1 (en) 2000-09-21
US6287783B1 (en) 2001-09-11
EP1166115A1 (en) 2002-01-02
US20020064888A1 (en) 2002-05-30
US6770447B2 (en) 2004-08-03

Similar Documents

Publication Publication Date Title
US6287783B1 (en) Optical assay device and method
US5308580A (en) Sample collection and analytical device
AU732463B2 (en) Methods and devices for mass transport assisted optical assays
US6143247A (en) Affinity binding-based system for detecting particulates in a fluid
US5106758A (en) Analytical test device and the use thereof
EP1546722B1 (en) Automated immunoassay cassette, apparatus and method
IE903118A1 (en) Test device including flow control means
AU771607B2 (en) Flow matrix assay device with movable separating member
JP3897265B2 (ja) 測定チップ表面への物質固定化方法及び装置
JPH11271218A (ja) 測定チップ
HK1076864B (en) Automated immunoassay cassette, apparatus and method
HK1112643A (en) Membrane array and analytical device
HK1061043B (en) Automated cassette module for an apparatus for conducting immunoassays and use thereof
AU5595901A (en) Methods and devices for mass transport assisted optical assays

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 00805077.5

Country of ref document: CN

AK Designated states

Kind code of ref document: A1

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
ENP Entry into the national phase

Ref document number: 2366307

Country of ref document: CA

Ref document number: 2366307

Country of ref document: CA

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: IN/PCT/2001/958/KOL

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2000916114

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2000 605207

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 37271/00

Country of ref document: AU

Ref document number: 1020017011848

Country of ref document: KR

WWP Wipo information: published in national office

Ref document number: 2000916114

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 1020017011848

Country of ref document: KR

WWG Wipo information: grant in national office

Ref document number: 37271/00

Country of ref document: AU

WWG Wipo information: grant in national office

Ref document number: 1020017011848

Country of ref document: KR