WO2000047197A3 - Agents d'alkylation destines au traitement de proliferation cellulaire - Google Patents

Agents d'alkylation destines au traitement de proliferation cellulaire Download PDF

Info

Publication number
WO2000047197A3
WO2000047197A3 PCT/US2000/003667 US0003667W WO0047197A3 WO 2000047197 A3 WO2000047197 A3 WO 2000047197A3 US 0003667 W US0003667 W US 0003667W WO 0047197 A3 WO0047197 A3 WO 0047197A3
Authority
WO
WIPO (PCT)
Prior art keywords
cellular proliferation
treatment
alkylating agents
alkylating agent
restenosis
Prior art date
Application number
PCT/US2000/003667
Other languages
English (en)
Other versions
WO2000047197A2 (fr
Inventor
Angelica Alvarado
Robert Eury
Irina D Pomerantseva
Michael Froix
Original Assignee
Quanam Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quanam Medical Corp filed Critical Quanam Medical Corp
Priority to CA002362883A priority Critical patent/CA2362883A1/fr
Priority to JP2000598150A priority patent/JP2002536406A/ja
Priority to EP00914574A priority patent/EP1150670A2/fr
Priority to AU35947/00A priority patent/AU3594700A/en
Publication of WO2000047197A2 publication Critical patent/WO2000047197A2/fr
Publication of WO2000047197A3 publication Critical patent/WO2000047197A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne une méthode d'inhibition de prolifération cellulaire associée à une condition d'hyperprolifération telle que la resténose. Cette méthode consiste à administrer un agent d'alkylation. L'invention concerne aussi un extenseur destiné à administrer l'agent localement.
PCT/US2000/003667 1999-02-12 2000-02-10 Agents d'alkylation destines au traitement de proliferation cellulaire WO2000047197A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002362883A CA2362883A1 (fr) 1999-02-12 2000-02-10 Agents d'alkylation destines au traitement de proliferation cellulaire
JP2000598150A JP2002536406A (ja) 1999-02-12 2000-02-10 細胞増殖の治療用アルキル化剤
EP00914574A EP1150670A2 (fr) 1999-02-12 2000-02-10 Agents d'alkylation destines au traitement de proliferation cellulaire
AU35947/00A AU3594700A (en) 1999-02-12 2000-02-10 Alkylating agents for treatment of cellular proliferation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11995199P 1999-02-12 1999-02-12
US60/119,951 1999-02-12

Publications (2)

Publication Number Publication Date
WO2000047197A2 WO2000047197A2 (fr) 2000-08-17
WO2000047197A3 true WO2000047197A3 (fr) 2001-04-05

Family

ID=22387376

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/003667 WO2000047197A2 (fr) 1999-02-12 2000-02-10 Agents d'alkylation destines au traitement de proliferation cellulaire

Country Status (5)

Country Link
EP (1) EP1150670A2 (fr)
JP (1) JP2002536406A (fr)
AU (1) AU3594700A (fr)
CA (1) CA2362883A1 (fr)
WO (1) WO2000047197A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002056872A2 (fr) * 2000-10-31 2002-07-25 Chemgenex Therapeutics, Inc. Compositions de colchicine anti-proliferatives et utilisations associees
DE10115740A1 (de) 2001-03-26 2002-10-02 Ulrich Speck Zubereitung für die Restenoseprophylaxe
US6537195B2 (en) 2001-05-07 2003-03-25 Xoft, Microtube, Inc. Combination x-ray radiation and drug delivery devices and methods for inhibiting hyperplasia
US7041046B2 (en) 2001-05-07 2006-05-09 Xoft, Inc. Combination ionizing radiation and immunomodulator delivery devices and methods for inhibiting hyperplasia
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991012846A1 (fr) * 1990-02-26 1991-09-05 Slepian Marvin J Procede et appareil de traitement d'organes tubulaires
WO1998008566A1 (fr) * 1996-08-30 1998-03-05 Duke University Manipulations de stress nitrosant et oxydatif dans le traitement d'une maladie
WO1998052944A1 (fr) * 1997-05-19 1998-11-26 Sugen, Inc. Composes d'heteroarylcarboxamide actifs contre les etats pathologiques lies aux proteine tyrosine kinases
WO1998057671A2 (fr) * 1997-06-18 1998-12-23 Boston Scientific Corporation Dispersions de polycarbonate-polyurethane pour revetements thromboresistants
WO1999001118A2 (fr) * 1997-07-01 1999-01-14 Atherogenics, Inc. Amelioration au moyen d'antioxydants de la therapie destinee aux etats d'hyperproliferation
EP0970711A2 (fr) * 1998-06-30 2000-01-12 Ethicon, Inc. Procédé de revêtement d'extenseurs vasculaires

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991012846A1 (fr) * 1990-02-26 1991-09-05 Slepian Marvin J Procede et appareil de traitement d'organes tubulaires
WO1998008566A1 (fr) * 1996-08-30 1998-03-05 Duke University Manipulations de stress nitrosant et oxydatif dans le traitement d'une maladie
WO1998052944A1 (fr) * 1997-05-19 1998-11-26 Sugen, Inc. Composes d'heteroarylcarboxamide actifs contre les etats pathologiques lies aux proteine tyrosine kinases
WO1998057671A2 (fr) * 1997-06-18 1998-12-23 Boston Scientific Corporation Dispersions de polycarbonate-polyurethane pour revetements thromboresistants
WO1999001118A2 (fr) * 1997-07-01 1999-01-14 Atherogenics, Inc. Amelioration au moyen d'antioxydants de la therapie destinee aux etats d'hyperproliferation
EP0970711A2 (fr) * 1998-06-30 2000-01-12 Ethicon, Inc. Procédé de revêtement d'extenseurs vasculaires

Also Published As

Publication number Publication date
JP2002536406A (ja) 2002-10-29
WO2000047197A2 (fr) 2000-08-17
EP1150670A2 (fr) 2001-11-07
AU3594700A (en) 2000-08-29
CA2362883A1 (fr) 2000-08-17

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