WO2000026362A3 - Proteines de la famille de la stomatine et leur utilisation comme proteines cibles pour le traitement de la douleur - Google Patents
Proteines de la famille de la stomatine et leur utilisation comme proteines cibles pour le traitement de la douleur Download PDFInfo
- Publication number
- WO2000026362A3 WO2000026362A3 PCT/DE1999/003434 DE9903434W WO0026362A3 WO 2000026362 A3 WO2000026362 A3 WO 2000026362A3 DE 9903434 W DE9903434 W DE 9903434W WO 0026362 A3 WO0026362 A3 WO 0026362A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- stomatin
- proteins
- family
- pain therapy
- target proteins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
L'invention concerne la stomatine et de nouvelles protéines de la famille de la stomatine, notamment la N-stomatine contenant 287 acides aminés, son ADNc codant ayant une longueur de 1847 nucléotides. L'invention concerne également leur utilisation comme protéines cibles pour le traitement des douleurs et leur utilisation pour la production d'agents thérapeutiques pour le traitement de la douleur, analgésiques/anesthésiques, pour la constitution de gènes, pour le développement de substances d'importance pharmaceutique et dans kits de diagnostic.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19850015.7 | 1998-10-30 | ||
DE1998150015 DE19850015A1 (de) | 1998-10-30 | 1998-10-30 | Proteine der Stomatinfamilie und ihre Verwendung als Zielproteine für die Schm erztherapie |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000026362A2 WO2000026362A2 (fr) | 2000-05-11 |
WO2000026362A3 true WO2000026362A3 (fr) | 2000-06-22 |
Family
ID=7886124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/DE1999/003434 WO2000026362A2 (fr) | 1998-10-30 | 1999-10-28 | Proteines de la famille de la stomatine et leur utilisation comme proteines cibles pour le traitement de la douleur |
Country Status (2)
Country | Link |
---|---|
DE (1) | DE19850015A1 (fr) |
WO (1) | WO2000026362A2 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2813499B1 (fr) | 2000-09-04 | 2004-11-26 | Pasteur Institut | Mammifere non-humain mutant pour l'expression de la sous- unite alpha6 du recepteur nicotinique de l'acetylcholine et utilisation pour le criblage de substances susceptibles d'interagir avec ce recepteur |
IL151980A0 (en) * | 2002-09-29 | 2003-04-10 | Yeda Res & Dev | Resistin binding proteins, their preparation and use |
AU2003283326A1 (en) * | 2002-10-30 | 2004-05-25 | Max-Delbruck-Centrum Fur Molekulare Medizin (Mdc) Berlin-Buch | Method for identifying compounds which inhibit mechanotransduction in neurons |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998030690A1 (fr) * | 1997-01-09 | 1998-07-16 | Incyte Pharmaceuticals, Inc. | Nouvelle proteine membranaire humaine |
WO1999025825A2 (fr) * | 1997-11-13 | 1999-05-27 | Genset | ADNc ETENDUS POUR PROTEINES SECRETEES |
-
1998
- 1998-10-30 DE DE1998150015 patent/DE19850015A1/de not_active Withdrawn
-
1999
- 1999-10-28 WO PCT/DE1999/003434 patent/WO2000026362A2/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998030690A1 (fr) * | 1997-01-09 | 1998-07-16 | Incyte Pharmaceuticals, Inc. | Nouvelle proteine membranaire humaine |
WO1999025825A2 (fr) * | 1997-11-13 | 1999-05-27 | Genset | ADNc ETENDUS POUR PROTEINES SECRETEES |
Non-Patent Citations (6)
Title |
---|
BARNES T M ET AL: "THE CAENORHABDITIS ELEGANS BEHAVIORAL GENE UNC-24 ENCODES A NOVEL BIPARTITE PROTEIN SIMILAR TO BOTH ERYTHROCYTE BAND 7.2 (STOMATIN) AND NONSPECIFIC LIPID TRANSFER PROTEIN", JOURNAL OF NEUROCHEMISTRY,US,NEW YORK, NY, vol. 67, 1 January 1996 (1996-01-01), pages 46 - 55, XP002063568, ISSN: 0022-3042 * |
MANNSFELDT, A.G. ET AL.: "Stomatin, a MEC-2 Like Protein, Is Expressed by Mammalian Sensory Neurons", MOL. CELL. NEUROSCI., vol. 13, no. 6, June 1999 (1999-06-01), pages 391 - 404, XP000889811 * |
RAJARAM, S. ET AL.: "unc-1: A stomatin homologue controls sensitivity to volatile anesthetics in Caenorhabditis elegans.", PROC, NATL. ACAD. SCI., vol. 95, July 1998 (1998-07-01), pages 8761 - 8766, XP002132341 * |
SCHLEGEL W ET AL: "Cloning and analysis of a cDNA encoding the BALB/c murine erythrocyte band 7 integral membrane protein", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES,GB,ELSEVIER SCIENCE PUBLISHERS, BARKING, vol. 178, no. 1, 31 October 1996 (1996-10-31), pages 115 - 118, XP004043348, ISSN: 0378-1119 * |
SEIDEL G ET AL: "Molecular cloning of hSLP-1, a novel human brain-specific member of the band 7/MEC-2 family similar to Caenorhabditis elegans UNC-24", GENE,NL,ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, vol. 225, no. 1-2, 28 December 1998 (1998-12-28), pages 23 - 29, XP004153617, ISSN: 0378-1119 * |
STEWART G W ET AL: "ISOLATION OF CDNA CODING FOR AN UBIQUITOUS MEMBRANE PROTEIN DEFICIENT IN HIGH NA+, LOW K STOMATOCYTIC ERYTHROCYTES", BLOOD,US,PHILADELPHIA, PA, vol. 79, 1 January 1992 (1992-01-01), pages 1593 - 1601, XP002063567, ISSN: 0006-4971 * |
Also Published As
Publication number | Publication date |
---|---|
DE19850015A1 (de) | 2000-05-04 |
WO2000026362A2 (fr) | 2000-05-11 |
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