WO2000024767A3 - Human membrane associated protein 'zsig24' and encoding gene as marker for metabolic disease - Google Patents

Human membrane associated protein 'zsig24' and encoding gene as marker for metabolic disease Download PDF

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Publication number
WO2000024767A3
WO2000024767A3 PCT/US1999/024662 US9924662W WO0024767A3 WO 2000024767 A3 WO2000024767 A3 WO 2000024767A3 US 9924662 W US9924662 W US 9924662W WO 0024767 A3 WO0024767 A3 WO 0024767A3
Authority
WO
WIPO (PCT)
Prior art keywords
zsig24
marker
associated protein
encoding gene
metabolic disease
Prior art date
Application number
PCT/US1999/024662
Other languages
French (fr)
Other versions
WO2000024767A2 (en
Inventor
Paul O Sheppard
Laura J Jelinek
Theodore E Whitmore
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to CA002347679A priority Critical patent/CA2347679A1/en
Priority to AU11289/00A priority patent/AU1128900A/en
Publication of WO2000024767A2 publication Critical patent/WO2000024767A2/en
Publication of WO2000024767A3 publication Critical patent/WO2000024767A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Rehabilitation Therapy (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides methods for identifying abnormalities in human chromosome (11) that are linked to defects in glucose metabolism. The present invention also provides methods for identifying polymorphisms in a new human gene that resides on chromosome 11q23-q24, a locus linked with a heritable form of diabetes.
PCT/US1999/024662 1998-10-23 1999-10-20 Human membrane associated protein 'zsig24' and encoding gene as marker for metabolic disease WO2000024767A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002347679A CA2347679A1 (en) 1998-10-23 1999-10-20 Human gene marker for metabolic disease
AU11289/00A AU1128900A (en) 1998-10-23 1999-10-20 Human gene marker for metabolic disease

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US17800998A 1998-10-23 1998-10-23
US09/178,009 1998-10-23
US33939599A 1999-06-23 1999-06-23
US09/339,395 1999-06-23

Publications (2)

Publication Number Publication Date
WO2000024767A2 WO2000024767A2 (en) 2000-05-04
WO2000024767A3 true WO2000024767A3 (en) 2000-08-10

Family

ID=26873865

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/024662 WO2000024767A2 (en) 1998-10-23 1999-10-20 Human membrane associated protein 'zsig24' and encoding gene as marker for metabolic disease

Country Status (3)

Country Link
AU (1) AU1128900A (en)
CA (1) CA2347679A1 (en)
WO (1) WO2000024767A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999035158A1 (en) * 1998-01-07 1999-07-15 Human Genome Sciences, Inc. 36 human secreted proteins
WO2000000623A1 (en) * 1998-06-30 2000-01-06 Syngenta Participations Ag Hmp-p kinase and tmp-ppase from arabidopsis thaliana and their use in herbicide screening

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999035158A1 (en) * 1998-01-07 1999-07-15 Human Genome Sciences, Inc. 36 human secreted proteins
WO2000000623A1 (en) * 1998-06-30 2000-01-06 Syngenta Participations Ag Hmp-p kinase and tmp-ppase from arabidopsis thaliana and their use in herbicide screening

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL EBI; 1 January 1998 (1998-01-01), INOUE D. ET AL.: "PATCHED PROTEIN HOMOLOG 2 (PTC2)", XP002138095 *
DATABASE EMBL EBI; 18 April 1997 (1997-04-18), ADAMS M.D. ET AL.: "EST181111 Jurkat T-cells V Homo sapiens cDNA 5' end", XP002138096 *
DATABASE EMBL EBI; 5 October 1998 (1998-10-05), STRAUSBERG R.: "qb50a10.x1 NCI_CGAP_Brn23 Homo sapiens cDNA clone IMAGE:1703514 3'", XP002138094 *
HANSON R L ET AL: "An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians.", AMERICAN JOURNAL OF HUMAN GENETICS, (1998 OCT) 63 (4) 1130-8., XP002138093 *

Also Published As

Publication number Publication date
AU1128900A (en) 2000-05-15
CA2347679A1 (en) 2000-05-04
WO2000024767A2 (en) 2000-05-04

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