WO2000021505A3 - Composition pour administration parenterale de principes actifs - Google Patents

Composition pour administration parenterale de principes actifs Download PDF

Info

Publication number
WO2000021505A3
WO2000021505A3 PCT/EP1999/007300 EP9907300W WO0021505A3 WO 2000021505 A3 WO2000021505 A3 WO 2000021505A3 EP 9907300 W EP9907300 W EP 9907300W WO 0021505 A3 WO0021505 A3 WO 0021505A3
Authority
WO
WIPO (PCT)
Prior art keywords
composition
parenteral administration
active agents
support material
relates
Prior art date
Application number
PCT/EP1999/007300
Other languages
German (de)
English (en)
Other versions
WO2000021505A2 (fr
Inventor
Juergen Grande
Silke Schuth
Gitte Boehm
Holger Bengs
Original Assignee
Aventis Res & Tech Gmbh & Co
Juergen Grande
Silke Schuth
Gitte Boehm
Holger Bengs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Res & Tech Gmbh & Co, Juergen Grande, Silke Schuth, Gitte Boehm, Holger Bengs filed Critical Aventis Res & Tech Gmbh & Co
Priority to EP99948917A priority Critical patent/EP1124538A2/fr
Priority to JP2000575481A priority patent/JP2002527376A/ja
Priority to CA002346670A priority patent/CA2346670A1/fr
Priority to AU61989/99A priority patent/AU6198999A/en
Publication of WO2000021505A2 publication Critical patent/WO2000021505A2/fr
Publication of WO2000021505A3 publication Critical patent/WO2000021505A3/fr
Priority to NO20011670A priority patent/NO20011670L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne une composition pour administration parentérale de principes actifs, contenant un excipient et au moins un principe actif. L'excipient contient des microparticules sphériques de diamètre moyen compris entre 1 nm et 100 νm, qui se composent entièrement ou en partie d'au moins un polysaccharide linéaire non soluble dans l'eau, notamment un polyglucane linéaire. L'invention concerne en outre une suspension contenant ladite composition, ainsi que son utilisation.
PCT/EP1999/007300 1998-10-15 1999-10-02 Composition pour administration parenterale de principes actifs WO2000021505A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP99948917A EP1124538A2 (fr) 1998-10-15 1999-10-02 Composition pour administration parenterale de principes actifs
JP2000575481A JP2002527376A (ja) 1998-10-15 1999-10-02 活性物質非経口投与用組成物
CA002346670A CA2346670A1 (fr) 1998-10-15 1999-10-02 Composition pour administration parenterale de composes actifs
AU61989/99A AU6198999A (en) 1998-10-15 1999-10-02 Composition for the parenteral administration of active agents
NO20011670A NO20011670L (no) 1998-10-15 2001-04-03 Preparat for parenteral administrering av aktive forbindelser

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE1998147593 DE19847593A1 (de) 1998-10-15 1998-10-15 Zusammensetzung für die parenterale Applikation von Wirkstoffen
DE19847593.4 1998-10-15

Publications (2)

Publication Number Publication Date
WO2000021505A2 WO2000021505A2 (fr) 2000-04-20
WO2000021505A3 true WO2000021505A3 (fr) 2000-09-21

Family

ID=7884587

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/007300 WO2000021505A2 (fr) 1998-10-15 1999-10-02 Composition pour administration parenterale de principes actifs

Country Status (8)

Country Link
EP (1) EP1124538A2 (fr)
JP (1) JP2002527376A (fr)
AU (1) AU6198999A (fr)
CA (1) CA2346670A1 (fr)
DE (1) DE19847593A1 (fr)
NO (1) NO20011670L (fr)
PL (1) PL347770A1 (fr)
WO (1) WO2000021505A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10022095B4 (de) * 2000-05-08 2005-07-14 Südzucker AG Mannheim/Ochsenfurt Gel aus einem Poly-α-1,4-Glucan und Stärke
DE10119522A1 (de) * 2001-04-20 2002-12-05 Innovacell Biotechnologie Gmbh Herstellung und Anwendung einer Suspensionszusammensetzung mit einem Ultraschall-Kontrastmittel
SI3659437T1 (sl) 2004-01-23 2022-10-28 Eden Research Plc Postopki za uničevanje nematod, ki obsega uporabo inkapsulirane terpenske komponente
CN1997446B (zh) 2004-05-20 2012-01-04 伊顿研究有限公司 含有包封萜成分的中空葡聚糖颗粒或细胞壁颗粒的组合物、其制备和使用方法
US20080227805A1 (en) 2007-02-28 2008-09-18 Abbott Laboratories Sustained release parenteral formulations of buprenorphine

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2328732A1 (fr) * 1975-10-21 1977-05-20 Takeda Chemical Industries Ltd Perles de polysaccharide a base de b-1,3-glucane
EP0053580A2 (fr) * 1980-11-29 1982-06-09 Sandoz Ag Compositions pharmaceutiques
WO1995031553A1 (fr) * 1994-05-18 1995-11-23 Institut Für Genbiologische Forschung Berlin Gmbh SEQUENCES D'ADN CODANT DES ENZYMES SUSCEPTIBLES DE FACILITER LA SYNTHESE D'α-1,4 GLYCANNES LINEAIRES CHEZ LES VEGETAUX, LES CHAMPIGNONS ET LES MICRO-ORGANISMES
WO1999011695A1 (fr) * 1997-08-28 1999-03-11 Aventis Research & Technologies Gmbh & Co Kg Micro particules spheriques contenant des polysaccharides lineaires
WO1999052506A1 (fr) * 1998-04-09 1999-10-21 Axiva Gmbh Excipient de principe actif particulaire destine a une application pulmonaire
WO2000012590A1 (fr) * 1998-08-28 2000-03-09 Celanese Ventures Gmbh Procede de preparation de microparticules spheriques, consistant en partie ou en totalite en au moins un polyglucane contenant des ramifications non solubles dans l'eau, et microparticules obtenues a l'aide dudit procede

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2328732A1 (fr) * 1975-10-21 1977-05-20 Takeda Chemical Industries Ltd Perles de polysaccharide a base de b-1,3-glucane
EP0053580A2 (fr) * 1980-11-29 1982-06-09 Sandoz Ag Compositions pharmaceutiques
WO1995031553A1 (fr) * 1994-05-18 1995-11-23 Institut Für Genbiologische Forschung Berlin Gmbh SEQUENCES D'ADN CODANT DES ENZYMES SUSCEPTIBLES DE FACILITER LA SYNTHESE D'α-1,4 GLYCANNES LINEAIRES CHEZ LES VEGETAUX, LES CHAMPIGNONS ET LES MICRO-ORGANISMES
WO1999011695A1 (fr) * 1997-08-28 1999-03-11 Aventis Research & Technologies Gmbh & Co Kg Micro particules spheriques contenant des polysaccharides lineaires
WO1999052506A1 (fr) * 1998-04-09 1999-10-21 Axiva Gmbh Excipient de principe actif particulaire destine a une application pulmonaire
WO2000012590A1 (fr) * 1998-08-28 2000-03-09 Celanese Ventures Gmbh Procede de preparation de microparticules spheriques, consistant en partie ou en totalite en au moins un polyglucane contenant des ramifications non solubles dans l'eau, et microparticules obtenues a l'aide dudit procede

Also Published As

Publication number Publication date
AU6198999A (en) 2000-05-01
WO2000021505A2 (fr) 2000-04-20
JP2002527376A (ja) 2002-08-27
NO20011670D0 (no) 2001-04-03
EP1124538A2 (fr) 2001-08-22
CA2346670A1 (fr) 2000-04-20
DE19847593A1 (de) 2000-04-20
PL347770A1 (en) 2002-04-22
NO20011670L (no) 2001-06-12

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