WO2000018212A8 - Platelet-derived growth factor c, dna coding therefor, and uses thereof - Google Patents

Platelet-derived growth factor c, dna coding therefor, and uses thereof

Info

Publication number
WO2000018212A8
WO2000018212A8 PCT/US1999/022668 US9922668W WO0018212A8 WO 2000018212 A8 WO2000018212 A8 WO 2000018212A8 US 9922668 W US9922668 W US 9922668W WO 0018212 A8 WO0018212 A8 WO 0018212A8
Authority
WO
WIPO (PCT)
Prior art keywords
platelet
growth factor
derived growth
dna coding
coding therefor
Prior art date
Application number
PCT/US1999/022668
Other languages
French (fr)
Other versions
WO2000018212A9 (en
WO2000018212A2 (en
Inventor
Ulf Eriksson
Karin Aase
Xuri Li
Annica Ponten
Marko Uutela
Kari Alitalo
Arne Oestman
Carl-Henrik Heldin
Christer Betsholz
Original Assignee
Ludwig Inst Cancer Res
Licentia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Inst Cancer Res, Licentia Ltd filed Critical Ludwig Inst Cancer Res
Priority to EP99952989A priority Critical patent/EP1123408A1/en
Priority to AU65029/99A priority patent/AU6502999A/en
Priority to CA002344561A priority patent/CA2344561A1/en
Priority to JP2000571742A priority patent/JP2002525086A/en
Publication of WO2000018212A2 publication Critical patent/WO2000018212A2/en
Publication of WO2000018212A9 publication Critical patent/WO2000018212A9/en
Publication of WO2000018212A8 publication Critical patent/WO2000018212A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials
PCT/US1999/022668 1998-09-30 1999-09-30 Platelet-derived growth factor c, dna coding therefor, and uses thereof WO2000018212A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP99952989A EP1123408A1 (en) 1998-09-30 1999-09-30 Platelet-derived growth factor c, dna coding therefor, and uses thereof
AU65029/99A AU6502999A (en) 1998-09-30 1999-09-30 Platelet-derived growth factor c, dna coding therefor, and uses thereof
CA002344561A CA2344561A1 (en) 1998-09-30 1999-09-30 Platelet-derived growth factor c, dna coding therefor, and uses thereof
JP2000571742A JP2002525086A (en) 1998-09-30 1999-09-30 Platelet-derived growth factor C, DNA encoding the same, and use thereof

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US10246198P 1998-09-30 1998-09-30
US60/102,461 1998-09-30
US10810998P 1998-11-12 1998-11-12
US60/108,109 1998-11-12
US11074998P 1998-12-03 1998-12-03
US60/110,749 1998-12-03
US11300298P 1998-12-18 1998-12-18
US60/113,002 1998-12-18
US13542699P 1999-05-21 1999-05-21
US60/135,426 1999-05-21
US14402299P 1999-07-15 1999-07-15
US60/144,022 1999-07-15

Publications (3)

Publication Number Publication Date
WO2000018212A2 WO2000018212A2 (en) 2000-04-06
WO2000018212A9 WO2000018212A9 (en) 2000-09-08
WO2000018212A8 true WO2000018212A8 (en) 2007-11-22

Family

ID=27557649

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/022668 WO2000018212A2 (en) 1998-09-30 1999-09-30 Platelet-derived growth factor c, dna coding therefor, and uses thereof

Country Status (5)

Country Link
EP (1) EP1123408A1 (en)
JP (1) JP2002525086A (en)
CN (1) CN1330664A (en)
CA (1) CA2344561A1 (en)
WO (1) WO2000018212A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE405651T1 (en) 1998-03-17 2008-09-15 Genentech Inc POLYPEPTIDES HOMOLOGUE TO VEGF AND BMP1
EP1137773B1 (en) * 1998-12-07 2008-08-13 ZymoGenetics, Inc. Growth factor homolog zvegf3
US6432673B1 (en) 1998-12-07 2002-08-13 Zymogenetics, Inc. Growth factor homolog ZVEGF3
WO2000059940A2 (en) * 1999-04-06 2000-10-12 Eli Lilly And Company Platelet-derived growth factor related gene and protein
US6893637B1 (en) 1999-10-21 2005-05-17 Zymogenetics, Inc. Method of treating fibrosis
EP1335024A4 (en) * 2000-10-19 2004-09-01 Kyowa Hakko Kogyo Kk Antibody inhibiting vplf activity
CA2439612A1 (en) 2001-03-09 2002-09-19 Janssen Pharmaceutica N.V. Modulation of smooth muscle cell proliferation
US20060104978A1 (en) * 2003-10-24 2006-05-18 Ludwig Institute For Cancer Research Methods and compositions for PDGF-C activation and inhibition
US20060024302A1 (en) 2004-03-05 2006-02-02 Ludwig Institute For Cancer Research Chimeric anti-VEGF-D antibodies and humanized anti-VEGF-D antibodies and methods of using same
WO2005092921A2 (en) * 2004-03-22 2005-10-06 Eli Lilly And Company Placental growth factor splice variants and their uses
DE602006020881D1 (en) 2005-08-15 2011-05-05 Vegenics Pty Ltd ENEN FEATURES
ES2497641T3 (en) 2006-05-17 2014-09-23 The Ludwig Institute For Cancer Research Direction to the regulation of VEGF-B of fatty acid transporters to modulate human diseases
CN101392026B (en) * 2008-10-09 2011-11-09 黄岚 Polypeptide for preventing and treating fibrotic disease and liver cancer
BR112014025560A2 (en) 2012-04-24 2017-07-04 Thrombogenics Nv anti-pdgf-c antibodies
CN104744565A (en) * 2015-04-06 2015-07-01 苏州普罗达生物科技有限公司 Antagonistic polypeptide for vascular endothelial growth factor C and application of antagonistic polypeptides
CN104693285A (en) * 2015-04-06 2015-06-10 苏州普罗达生物科技有限公司 Vascular-endothelial-growth-factor-C antagonistic polypeptide and application thereof
CN104693286A (en) * 2015-04-06 2015-06-10 苏州普罗达生物科技有限公司 Vascular endothelial growth factor C antagonistic polypeptide and application thereof
CN105175546A (en) * 2015-05-27 2015-12-23 连祺周 Fusion protein of human vascular endothelial growth factor and epidermal growth factor-like domain 7
AU2017290762A1 (en) 2016-07-01 2019-01-31 Paracrine Therapeutics Ab Methods and compositions for PDGF-CC inhibition

Also Published As

Publication number Publication date
WO2000018212A9 (en) 2000-09-08
EP1123408A1 (en) 2001-08-16
WO2000018212A2 (en) 2000-04-06
JP2002525086A (en) 2002-08-13
CN1330664A (en) 2002-01-09
CA2344561A1 (en) 2000-04-06

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