WO2000008156A3 - Dna replication- and repair-associated proteins - Google Patents

Dna replication- and repair-associated proteins Download PDF

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Publication number
WO2000008156A3
WO2000008156A3 PCT/US1999/017800 US9917800W WO0008156A3 WO 2000008156 A3 WO2000008156 A3 WO 2000008156A3 US 9917800 W US9917800 W US 9917800W WO 0008156 A3 WO0008156 A3 WO 0008156A3
Authority
WO
WIPO (PCT)
Prior art keywords
repair
dna replication
associated proteins
drasp
provides
Prior art date
Application number
PCT/US1999/017800
Other languages
French (fr)
Other versions
WO2000008156A2 (en
Inventor
Y Tom Tang
Neil C Corley
Mariah R Baughn
Roopa Reddy
Karl J Guegler
Henry Yue
Original Assignee
Incyte Pharma Inc
Y Tom Tang
Neil C Corley
Mariah R Baughn
Roopa Reddy
Karl J Guegler
Henry Yue
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Y Tom Tang, Neil C Corley, Mariah R Baughn, Roopa Reddy, Karl J Guegler, Henry Yue filed Critical Incyte Pharma Inc
Priority to JP2000563781A priority Critical patent/JP2002525032A/en
Priority to AU53399/99A priority patent/AU5339999A/en
Priority to CA002339086A priority patent/CA2339086A1/en
Priority to EP99939036A priority patent/EP1100909A2/en
Publication of WO2000008156A2 publication Critical patent/WO2000008156A2/en
Publication of WO2000008156A3 publication Critical patent/WO2000008156A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The invention provides human DNA replication- and repair-associated proteins (DRASP) and polynucleotides which identify and encode DRASP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of DRASP.
PCT/US1999/017800 1998-08-07 1999-08-06 Dna replication- and repair-associated proteins WO2000008156A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000563781A JP2002525032A (en) 1998-08-07 1999-08-06 DNA replication and repair related proteins
AU53399/99A AU5339999A (en) 1998-08-07 1999-08-06 Dna replication- and repair-associated proteins
CA002339086A CA2339086A1 (en) 1998-08-07 1999-08-06 Dna replication- and repair-associated proteins
EP99939036A EP1100909A2 (en) 1998-08-07 1999-08-06 Dna replication- and repair-associated proteins

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US13065098A 1998-08-07 1998-08-07
US15524598P 1998-08-07 1998-08-07
US60/155,245 1998-08-07
US15518198P 1998-08-27 1998-08-27
US14098298A 1998-08-27 1998-08-27
US60/155,181 1998-08-27

Publications (2)

Publication Number Publication Date
WO2000008156A2 WO2000008156A2 (en) 2000-02-17
WO2000008156A3 true WO2000008156A3 (en) 2000-05-11

Family

ID=27494872

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/017800 WO2000008156A2 (en) 1998-08-07 1999-08-06 Dna replication- and repair-associated proteins

Country Status (1)

Country Link
WO (1) WO2000008156A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997005157A1 (en) * 1995-08-01 1997-02-13 Sloan-Kettering Institute For Cancer Research Gene encoding the human homolog of mad2
WO1997034640A1 (en) * 1996-03-22 1997-09-25 The Johns Hopkins University A novel cancer drug screen based on cell cycle uncoupling
WO1999038972A2 (en) * 1998-01-28 1999-08-05 Chiron Corporation Human genes and gene expression products ii

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997005157A1 (en) * 1995-08-01 1997-02-13 Sloan-Kettering Institute For Cancer Research Gene encoding the human homolog of mad2
WO1997034640A1 (en) * 1996-03-22 1997-09-25 The Johns Hopkins University A novel cancer drug screen based on cell cycle uncoupling
WO1999038972A2 (en) * 1998-01-28 1999-08-05 Chiron Corporation Human genes and gene expression products ii

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CAHILL D P ET AL: "Characterization of MAD2B and other mitotic spindle checkpoint genes.", GENOMICS, (1999 JUN 1) 58 (2) 181-7., XP000852916 *
HILLIER L ET AL: "Homo sapiens cDNA clone similar to SW:MAD2_Yeast Mitotic MAD2 protein", EMEST DATABASE ENTRY HS458369, ACCESSION NUMBER W79458, 27 June 1996 (1996-06-27), XP002123193 *
LI Y ET AL: "Identification of a human mitotic checkpoint gene: hsMAD2.", SCIENCE, (1996 OCT 11) 274 (5285) 246-8., XP002123190 *
MARRA M ET AL: "Mus musculus cDNA clone; Mitotic feedback control protein MADP2 homolog", EMEST DATABASE ENTRY MMAA44657, ACCESSION NUMBER AA144657, 14 December 1997 (1997-12-14), XP002123192 *
NATIONAL CANCER INSTITUE, CANCER GENOME ANATOMY PROJECT (CGAP): "Homo sapiens cDNA clone", EMEST DATABASE ENTRY AA808954, ACCESSSION NUMBER AA808954, 16 February 1998 (1998-02-16), XP002123191 *

Also Published As

Publication number Publication date
WO2000008156A2 (en) 2000-02-17

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