WO2000008143A3 - Gene isolated on the short arm of human chromosome 17 - Google Patents

Gene isolated on the short arm of human chromosome 17 Download PDF

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Publication number
WO2000008143A3
WO2000008143A3 PCT/DE1999/002479 DE9902479W WO0008143A3 WO 2000008143 A3 WO2000008143 A3 WO 2000008143A3 DE 9902479 W DE9902479 W DE 9902479W WO 0008143 A3 WO0008143 A3 WO 0008143A3
Authority
WO
WIPO (PCT)
Prior art keywords
short arm
dna molecules
human chromosome
vectors
gene isolated
Prior art date
Application number
PCT/DE1999/002479
Other languages
German (de)
French (fr)
Other versions
WO2000008143A2 (en
Inventor
Peter Seranski
Annemarie Poustka
Hans Lehrrach
Uwe Radelof
Original Assignee
Deutsches Krebsforsch
Max Planck Inst Fuer Molekular
Peter Seranski
Annemarie Poustka
Hans Lehrrach
Uwe Radelof
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deutsches Krebsforsch, Max Planck Inst Fuer Molekular, Peter Seranski, Annemarie Poustka, Hans Lehrrach, Uwe Radelof filed Critical Deutsches Krebsforsch
Priority to AU64629/99A priority Critical patent/AU6462999A/en
Publication of WO2000008143A2 publication Critical patent/WO2000008143A2/en
Publication of WO2000008143A3 publication Critical patent/WO2000008143A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention relates to DNA molecules containing information for a human gene that was isolated on the short arm of chromosome 17. The invention also relates to vectors containing said DNA molecules. In one embodiment, said vectors are suitable for expression of the inventive DNA molecules in prokaryotes or eukaryotes. The invention further relates to medicaments and diagnostic compositions containing said DNA molecules or vectors, the protein coded thereby or an antibody that specifically recognizes said protein.
PCT/DE1999/002479 1998-08-07 1999-08-06 Gene isolated on the short arm of human chromosome 17 WO2000008143A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU64629/99A AU6462999A (en) 1998-08-07 1999-08-06 Gene isolated on the short arm of human chromosome 17

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19835910.1 1998-08-07
DE19835910A DE19835910C1 (en) 1998-08-07 1998-08-07 Gene isolated on the short arm of human chromosome 17

Publications (2)

Publication Number Publication Date
WO2000008143A2 WO2000008143A2 (en) 2000-02-17
WO2000008143A3 true WO2000008143A3 (en) 2000-06-15

Family

ID=7876883

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1999/002479 WO2000008143A2 (en) 1998-08-07 1999-08-06 Gene isolated on the short arm of human chromosome 17

Country Status (3)

Country Link
AU (1) AU6462999A (en)
DE (1) DE19835910C1 (en)
WO (1) WO2000008143A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7033790B2 (en) 2001-04-03 2006-04-25 Curagen Corporation Proteins and nucleic acids encoding same

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015639A1 (en) * 1997-09-19 1999-04-01 Mcgill University Polymorphic cag repeat-containing gene and uses thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015639A1 (en) * 1997-09-19 1999-04-01 Mcgill University Polymorphic cag repeat-containing gene and uses thereof

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMESTS E.M.B.L Databases; 6 April 1998 (1998-04-06), PHILIBERT R ET AL: "Homo sapiens trinucleotide repeat ctg-37", XP002130828 *
DATABASE GENESEQ E.M.B.L Databases; 25 June 1999 (1999-06-25), BENKELFAT C ET AL: "Human hGT1 DNA", XP002130829 *
IMAI Y ET AL: "Cloning of a retinoic acid-induced gene, GT1, in the embryonal carcinoma cell line P19: neuron-specific expression in the mouse brain", BRAIN RES MOL BRAIN RES, vol. 31, no. 1-2, July 1995 (1995-07-01), pages 1 - 9, XP002093328 *
PHILIBERT R ET AL: "The characterization and sequence analysis of thirty CTG-repeat containing genomic cosmid clones", EUR J HUM GENET, vol. 6, no. 1, January 1998 (1998-01-01), pages 89 - 94, XP002093332 *
SERANSKI P ET AL: "Molecular analysis of the human chromosome 17p11.2: From breakpoint identification to sequencing and gene analysis", J. MOL. MED., vol. 76, no. 6, May 1998 (1998-05-01), pages B38 - P143, XP002130827 *
WILGENBUS K ET AL: "Molecular characterization of a genetically unstable region containing the SMS critical area and a breakpoint cluster for human PNETs", GENOMICS, vol. 42, no. 1, 15 May 1997 (1997-05-15), pages 1 - 10, XP000876831 *

Also Published As

Publication number Publication date
DE19835910C1 (en) 2000-05-04
AU6462999A (en) 2000-02-28
WO2000008143A2 (en) 2000-02-17

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