WO2000006771A2 - Nucleic acid labeling compounds - Google Patents

Nucleic acid labeling compounds Download PDF

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Publication number
WO2000006771A2
WO2000006771A2 PCT/US1999/012390 US9912390W WO0006771A2 WO 2000006771 A2 WO2000006771 A2 WO 2000006771A2 US 9912390 W US9912390 W US 9912390W WO 0006771 A2 WO0006771 A2 WO 0006771A2
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
alkyl
aryl
labeling compound
probe
Prior art date
Application number
PCT/US1999/012390
Other languages
English (en)
French (fr)
Other versions
WO2000006771A3 (en
WO2000006771A9 (en
Inventor
Glenn H. Mcgall
Anthony D. Barone
Original Assignee
Affymetrix, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affymetrix, Inc. filed Critical Affymetrix, Inc.
Priority to AT99937150T priority Critical patent/ATE296833T1/de
Priority to AU52035/99A priority patent/AU5203599A/en
Priority to EP99937150A priority patent/EP1124838B1/en
Priority to CA002339016A priority patent/CA2339016A1/en
Priority to DE69925624T priority patent/DE69925624T2/de
Priority to JP2000562553A priority patent/JP2002521495A/ja
Publication of WO2000006771A2 publication Critical patent/WO2000006771A2/en
Publication of WO2000006771A3 publication Critical patent/WO2000006771A3/en
Publication of WO2000006771A9 publication Critical patent/WO2000006771A9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
PCT/US1999/012390 1998-07-31 1999-07-20 Nucleic acid labeling compounds WO2000006771A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AT99937150T ATE296833T1 (de) 1998-07-31 1999-07-20 Nukleinsäure-markierungsverbindungen
AU52035/99A AU5203599A (en) 1998-07-31 1999-07-20 Nucleic acid labeling compounds
EP99937150A EP1124838B1 (en) 1998-07-31 1999-07-20 Nucleic acid labeling compounds
CA002339016A CA2339016A1 (en) 1998-07-31 1999-07-20 Nucleic acid labeling compounds
DE69925624T DE69925624T2 (de) 1998-07-31 1999-07-20 Nukleinsäure-markierungsverbindungen
JP2000562553A JP2002521495A (ja) 1998-07-31 1999-07-20 核酸標識化合物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/126,645 US20010018514A1 (en) 1998-07-31 1998-07-31 Nucleic acid labeling compounds
US09/126,645 1998-07-31

Publications (3)

Publication Number Publication Date
WO2000006771A2 true WO2000006771A2 (en) 2000-02-10
WO2000006771A3 WO2000006771A3 (en) 2001-06-21
WO2000006771A9 WO2000006771A9 (en) 2002-08-22

Family

ID=22425958

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/012390 WO2000006771A2 (en) 1998-07-31 1999-07-20 Nucleic acid labeling compounds

Country Status (8)

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US (5) US20010018514A1 (US06844433-20050118-C00004.png)
EP (2) EP1124838B1 (US06844433-20050118-C00004.png)
JP (2) JP2002521495A (US06844433-20050118-C00004.png)
AT (1) ATE296833T1 (US06844433-20050118-C00004.png)
AU (1) AU5203599A (US06844433-20050118-C00004.png)
CA (1) CA2339016A1 (US06844433-20050118-C00004.png)
DE (1) DE69925624T2 (US06844433-20050118-C00004.png)
WO (1) WO2000006771A2 (US06844433-20050118-C00004.png)

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