WO1999055456A1 - Method of synthesizing a plurality of products - Google Patents
Method of synthesizing a plurality of products Download PDFInfo
- Publication number
- WO1999055456A1 WO1999055456A1 PCT/GB1999/001281 GB9901281W WO9955456A1 WO 1999055456 A1 WO1999055456 A1 WO 1999055456A1 GB 9901281 W GB9901281 W GB 9901281W WO 9955456 A1 WO9955456 A1 WO 9955456A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- articles
- micro
- article
- reactor
- synthesis
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00281—Individual reactor vessels
- B01J2219/00295—Individual reactor vessels the reactor vessels having pervious side walls
- B01J2219/00297—"Tea bags"
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/00459—Beads
- B01J2219/00461—Beads and reaction vessel together
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00457—Dispensing or evacuation of the solid phase support
- B01J2219/00459—Beads
- B01J2219/00461—Beads and reaction vessel together
- B01J2219/00463—Directed sorting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/005—Beads
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00542—Alphanumeric characters
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00547—Bar codes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00565—Electromagnetic means
- B01J2219/00567—Transponder chips
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00592—Split-and-pool, mix-and-divide processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/11—Compounds covalently bound to a solid support
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL13908999A IL139089A0 (en) | 1998-04-25 | 1999-04-26 | Method of synthesizing a plurality of products |
AU37172/99A AU746309B2 (en) | 1998-04-25 | 1999-04-26 | Method of synthesizing a plurality of products |
EP99919369A EP1079919A1 (en) | 1998-04-25 | 1999-04-26 | Method of synthesizing a plurality of products |
JP2000545643A JP2002512878A (en) | 1998-04-25 | 1999-04-26 | How to synthesize multiple products |
CA002330124A CA2330124A1 (en) | 1998-04-25 | 1999-04-26 | Method of synthesizing a plurality of products |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9808783.6A GB9808783D0 (en) | 1998-04-25 | 1998-04-25 | Labelling of small articles |
GB9808783.6 | 1998-04-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999055456A1 true WO1999055456A1 (en) | 1999-11-04 |
Family
ID=10830934
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1999/001281 WO1999055456A1 (en) | 1998-04-25 | 1999-04-26 | Method of synthesizing a plurality of products |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1079919A1 (en) |
JP (1) | JP2002512878A (en) |
AU (1) | AU746309B2 (en) |
CA (1) | CA2330124A1 (en) |
GB (1) | GB9808783D0 (en) |
IL (1) | IL139089A0 (en) |
WO (1) | WO1999055456A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002083292A2 (en) * | 2001-04-18 | 2002-10-24 | 3 D Molecular Sciences Limited | Chemical libraries based on coded particles |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4631211A (en) * | 1985-03-25 | 1986-12-23 | Scripps Clinic & Research Foundation | Means for sequential solid phase organic synthesis and methods using the same |
WO1992009300A1 (en) * | 1990-11-21 | 1992-06-11 | Iterex Pharmaceuticals Ltd. Partnership | Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures |
WO1996024061A1 (en) * | 1995-02-02 | 1996-08-08 | Ontogen Corporation | Methods and apparatus for synthesizing labeled combinatorial chemical libraries |
WO1996036436A1 (en) * | 1995-04-25 | 1996-11-21 | Irori | Remotely programmable matrices with memories and uses thereof |
GB2306484A (en) * | 1995-10-26 | 1997-05-07 | Univ Hertfordshire | Solid support particle marked with a machine-readable code for use in Combinatorial Chemistry Techniques |
WO1997019958A1 (en) * | 1995-11-30 | 1997-06-05 | Wlodek Mandecki | Screening of drugs from chemical combinatorial libraries employing transponders |
WO1998053093A1 (en) * | 1997-05-23 | 1998-11-26 | Bioarray Solutions Llc | Color-encoding and in-situ interrogation of matrix-coupled chemical compounds |
-
1998
- 1998-04-25 GB GBGB9808783.6A patent/GB9808783D0/en not_active Ceased
-
1999
- 1999-04-26 IL IL13908999A patent/IL139089A0/en unknown
- 1999-04-26 AU AU37172/99A patent/AU746309B2/en not_active Ceased
- 1999-04-26 EP EP99919369A patent/EP1079919A1/en not_active Withdrawn
- 1999-04-26 JP JP2000545643A patent/JP2002512878A/en active Pending
- 1999-04-26 WO PCT/GB1999/001281 patent/WO1999055456A1/en not_active Application Discontinuation
- 1999-04-26 CA CA002330124A patent/CA2330124A1/en not_active Abandoned
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4631211A (en) * | 1985-03-25 | 1986-12-23 | Scripps Clinic & Research Foundation | Means for sequential solid phase organic synthesis and methods using the same |
WO1992009300A1 (en) * | 1990-11-21 | 1992-06-11 | Iterex Pharmaceuticals Ltd. Partnership | Synthesis of equimolar multiple oligomer mixtures, especially of oligopeptide mixtures |
WO1996024061A1 (en) * | 1995-02-02 | 1996-08-08 | Ontogen Corporation | Methods and apparatus for synthesizing labeled combinatorial chemical libraries |
WO1996036436A1 (en) * | 1995-04-25 | 1996-11-21 | Irori | Remotely programmable matrices with memories and uses thereof |
GB2306484A (en) * | 1995-10-26 | 1997-05-07 | Univ Hertfordshire | Solid support particle marked with a machine-readable code for use in Combinatorial Chemistry Techniques |
WO1997019958A1 (en) * | 1995-11-30 | 1997-06-05 | Wlodek Mandecki | Screening of drugs from chemical combinatorial libraries employing transponders |
WO1998053093A1 (en) * | 1997-05-23 | 1998-11-26 | Bioarray Solutions Llc | Color-encoding and in-situ interrogation of matrix-coupled chemical compounds |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002083292A2 (en) * | 2001-04-18 | 2002-10-24 | 3 D Molecular Sciences Limited | Chemical libraries based on coded particles |
WO2002083292A3 (en) * | 2001-04-18 | 2003-01-16 | 3 D Molecular Sciences Ltd | Chemical libraries based on coded particles |
Also Published As
Publication number | Publication date |
---|---|
GB9808783D0 (en) | 1998-06-24 |
AU3717299A (en) | 1999-11-16 |
JP2002512878A (en) | 2002-05-08 |
EP1079919A1 (en) | 2001-03-07 |
AU746309B2 (en) | 2002-04-18 |
CA2330124A1 (en) | 1999-11-04 |
IL139089A0 (en) | 2001-11-25 |
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Mei et al. | Figure 8 The sheer volume of data being produced by high-throughput screening is overwhelming users’ ability to interpret results using conventional means. Spotfire, from Spotfire, Inc., is one of a number of programs designed to help users mine the data and extract information. In this example, we see the results of several different assays combined in a multidimensional display. Users manipulate the slide bars to further select interesting results. A small cluster of interesting results is identified in the lower left comer, and the results for |
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