WO1999053777A1 - Complement nutritionnel pour femmes enceintes et allaitantes - Google Patents

Complement nutritionnel pour femmes enceintes et allaitantes Download PDF

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Publication number
WO1999053777A1
WO1999053777A1 PCT/EP1999/002668 EP9902668W WO9953777A1 WO 1999053777 A1 WO1999053777 A1 WO 1999053777A1 EP 9902668 W EP9902668 W EP 9902668W WO 9953777 A1 WO9953777 A1 WO 9953777A1
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WO
WIPO (PCT)
Prior art keywords
particularly preferred
vitamin
protein
milk
fibre
Prior art date
Application number
PCT/EP1999/002668
Other languages
English (en)
Inventor
Alice Lustenberger
Diane Elizabeth Clayton
Original Assignee
Novartis Nutrition Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Nutrition Ag filed Critical Novartis Nutrition Ag
Priority to AU37094/99A priority Critical patent/AU3709499A/en
Publication of WO1999053777A1 publication Critical patent/WO1999053777A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/16—Inorganic salts, minerals or trace elements
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

  • This invention provides a nutritional composition for pregnant and lactating women and food products or dietary supplements comprising said composition.
  • Constipation is common in pregnancy. This is thought to be related to the increase in circulating progesterone and possibly decreased levels of motilin. Dietary fibre has a major effect on colonic function and is a safe means to relieve pregnant women of their constipation.
  • Calcium is among the nutrients the recommended levels of which is increased proportionately more than that of energy and the other nutrients during pregnancy and lactation and taking extra milk or dairy products will normally provide additional calcium. - 2 -
  • lactose intolerant individuals need an alternative calcium source which contains no lactose. Lactose- intolerance is one of the major reasons for milk intolerance. Furthermore, it is known that exposure of the foetus via the placenta to cow's milk can result in primary sensitisation to cow's milk allergens, leading to positive proliferative responses when the infant is exposed to cow's milk after birth.
  • the present invention therefore, provides a nutritional composition for pregnant and lactating women comprising: a non-milk-derived protein source, a dietary fibre and/or fibre-like substance, a source of polyunsaturated fatty acids, minerals and vitamins recommended for pregnant and lactating women, characterized in that the composition is lactose-free and contains less than 2 % of milk or milk-derived products by weight of dry components of the composition.
  • the composition according to the invention contains less than 1.5 weight % (more preferred less than 1 weight%) by weight of dry components of the composition of milk or milk-derived products such as caseinates, particularly preferred the composition is milk-free, i.e. it contains no detectable levels of milk or milk-derived products. Lactose-free as used herein means that the composition contains no detectable lactose.
  • composition according to the invention comprises the following minerals and vitamins recommended for pregnant and lactating women: calcium, magnesium, iron, copper, zinc, iodine, vitamin A, vitamin E, vitamin B 1 f vitamin B 2 , vitamin B 6 , vitamin B ⁇ 2 , vitamin C, folic acid, niacin. - 3 -
  • composition of the invention preferably comprises the following daily amounts of essential nutrients:
  • dietary fibre and/or fibre-like substance preferably 4 to 6 g, particularly preferred 5 g, of polyunsaturated fatty acids
  • 1 g to 30 g of linoleic acid preferably 2.0 to 5.0 g, particularly preferred 3.0 g, 0.1 mg to 3.6 g calcium, preferably 320 to 530 mg, particularly preferred 400 mg, 0.1 mg to 1.1 g magnesium, preferably 60 to 90 mg, particularly preferred 75 mg, 0.01 mg to 90 mg iron, preferably 8 to 12 mg, particularly preferred 10 mg, 0.01 mg to 60 mg zinc, preferably 4 to 6 mg, particularly preferred 5 mg, 0.01 mg to 3 mg copper, preferably 0.1 to 0.4 mg, particularly preferred 0.25 mg, 0.01 mg to 0.6 mg iodine, preferably 24 to 36 ⁇ g, particularly preferred 30 ⁇ g, 0.01 mg to 4.0 mg vitamin A, preferably 80 to 120 ⁇ g, particularly preferred 100 ⁇ g, 0.01 mg to 40 mg vitamin E, preferably 2.4 to 3.6 mg, particularly preferred 3 mg, 0.01 mg to 5 mg vitamin B ⁇ , preferably 0.16 to 0.24 mg, particularly preferred 0.2 mg, 0.01 mg to 6 mg vitamin B 2 ,
  • non-milk-derived protein source egg protein, soy protein (particularly soy protein low in isoflavones), soy isolate, pea protein, pea hydrolysate, rice protein, rice hydrolysate, soy hydrolysate, wheat hydrolysate, potato hydrolysate, rapeseed protein, lupin protein, wheat protein and/or wheat isolate.
  • the non-milk-derived protein source is soy protein.
  • Suitable dietary fibres include insoluble and soluble fibres and mixtures thereof.
  • Suitable insoluble fibres include one or more members selected from the following group: cellulose, wheat fibre, soy fibre, pea fibre, oat fibre and beet fibre.
  • Suitable soluble fibres include one or more members selected from the following group: pectin, xanthan gum, hydrolysed guar gum and gum arabic.
  • Suitable substances with fibre-like activity are inulin and oligosaccharides such as hydrolysed inulin, soy- oligosaccharides, galacto- oligosaccharides, fructo-oligosaccharides and xylo-oligosaccharides.
  • Oligosaccharides are prebiotic substances with fibre-like physiological activity, i.e. they have mild laxative effect.
  • the composition comprises oligosaccharides and in particular fructo- oligosaccharides and/or xylo-oligosaccharides as fibre-like substances.
  • soluble and/or fiber-like substance to insoluble fiber can vary from 9:1 to 2:3, a preferrred weight ratio is about 2-4 part soluble fibers and/or fibre-like substance to about 1 part insoluble fibers.
  • DHA docosahexaenoic acid
  • DPA docosapentaenoic acid
  • EPA eicosapentaenoic acid
  • AA arachidonic acid
  • DTA Adrenic
  • Preferred sources of long chain polyunsaturated fatty acids are fish oil which typically contains 15 to 25% DHA and 5 to 15% EPA as well as sources from microalgae which typically contain 40% DHA. If the long-chain polyunsaturated fatty acid employed is of the precursor-type which still has to be metabolized to the active form in the body such as alpha-linolenic acid or linoleic acid, then the daily amount preferably lies in the range of 0.5 g to 12 g or 1 g to 30 g respectively.
  • the daily amount preferably lies in the range of 0.01 ⁇ g (preferably 1.0 ⁇ g) to 2.0 g of long-chain poly-unsaturated fatty acid. - 5 -
  • Suitable calcium forms are e.g. calcium phosphate, calcium citrate, calcium carbonate or calcium amino acid chelate.
  • Suitable magnesium forms are e.g. magnesium oxide or magnesium sulfate.
  • Suitable iron forms are e.g. iron pyrophosphate, iron polymaltose, iron sulphate or iron chelate.
  • Suitable zinc forms are e.g. zinc sulphate or zinc lactate.
  • Suitable copper forms are e.g. copper gluconate, copper sulphate or copper oxide.
  • Suitable iodine forms are e.g. potassium iodide or potassium iodate.
  • the nutritional composition further comprises one or more of the following minerals and vitamins: potassium, selenium, manganese, vitamin K, biotin, pantothenic acid, choline, vitamin D3 and beta-carotene.
  • Typical daily amounts of these minerals and vitamins are 0.1 mg to 5 g of potassium, 0.1 ⁇ g to 200 ⁇ g of selenium, 0.1 ⁇ g to 500 ⁇ g manganese, 0.1 ⁇ g to 200 ⁇ g vitamin K, 0.1 ⁇ g to 150 ⁇ g biotin, 0.1 ⁇ g to 5 mg panthotenic acid, 0.1 mg to 1 g choline, 0.1 ⁇ g to 30 ⁇ g of vitamin D3 and 0.1 mg to 30 mg of beta- carotene.
  • Suitable potassium forms are e.g. potassium citrate or potassium phosphate.
  • a suitable selenium form is e.g. selenium yeast.
  • a suitable manganese form is e.g. manganese phosphate.
  • the nutritional composition preferably further comprises a carbohydrate source. Typically daily amounts of 20 g to 70 g of a carbohydrate source are provided.
  • Suitable carbohydrate sources include maltodextrins, malt extract, cereals, fruit flakes, invert sugar, sucrose, fructose, dextrose and glucose, whereby maltodextrin and cereals are preferred. - 6 -
  • the nutritional composition may be in the form of a soup or drink such as a powdered cold or hot water instant drink or soup or a ready-to-consume liquid form, in the form of a bar such as. a cereal or fruit bar, in form of a salted or sweet biscuit or in the form of a meal replacement.
  • composition of the invention provides the daily amounts of essential nutrients in a single dose unit.
  • the nutritional compositions of the present invention can be formulated into food products or dietary supplements.
  • the invention also relates to food products comprising the nutritional composition of the invention.
  • the term "food product” is intended to cover the whole variety of foods and beverages, including but not limited to powdered instant drinks, baked products such as bread, crisp bread, crisp bread sandwiches, biscuits and cakes, dairy substitute foods, desserts, confectionary products, spreads, cereal and/or fruit bars, breakfast cereals, juices and the like.
  • Preferred food formats are powdered instant drinks and cereal bars.
  • Preferred as food products are those which are likely to be classified as "functional foods", i.e. foods that are similar in appearance to conventional foods and are intended to be consumed as part of a normal diet or as a supplement, but have been nutritionally tailored to perform physiological roles beyond the provision of simple nutrient requirements.
  • the invention also foresees dietary supplements comprising the composition of the invention.
  • dietary supplements comprising the composition of the invention.
  • the latter are intended for ingestion in pill, capsule, tablet, chewable candies, tabs or liquid form.
  • composition of the invention in the manufacture of a food product or dietary supplement for pregnant and lactating women.
  • the invention further provides a method for supplementing the extra-needs of essential nutrients of pregnant and lactating women and for treating and/or preventing constipation comprising administering to said pregnant and lactating women effective amounts of - 7 -
  • a nutritional composition comprising: a non-milk-derived protein source, a dietary fibre and/or fibre-like substance, a source of polyunsaturated fatty acids, minerals and vitamins recommended for pregnant and lactating women, whereby the composition is lactose-free and contains less than 2 % of milk or milk-derived products by weight of dry components of the composition.
  • a powdered cold water instant drink to be reconstituted by 35g powder in 150 ml cold water which has following profile: Recommended daily amount 35g
  • soya isolate 34 0% sucrose 18.0% fructo-oligosaccharides 15.6% encapsulated fish oil, BASF 9.6% maltodextrin DE20 8.6% cocoa powder 7.0% mineral mix 4.0% chocolate flavour 1 .5%
  • MCT oil is added to the maltodextrin and mixed for 10 minutes in a Carpentier mixer. Then the remaining ingredients are added to the maltodextrin blend and further mixed for 20 minutes.
  • Vitamin E acetate 50% 7.4%
  • Vitamin D3 1.75%
  • Vitamin A acetate 325 0.95%
  • soya isolate 12.0 % fructo-oligosaccharides 10.0 % banana flakes 7.5 % sunflower oil 7.5 %
  • VM (as in Example 1 ) 0.5 % source of microalgae oil DHASCO, Martek Biosciences Corporation 1.5 % soya lecithin 0.5 % antioxidant vit E 0.01 %
  • the glucose syrup and inverted sugar are heated up to 1 10°C.
  • the sunflower oil is first warmed separately to 50°C in a tank, then the soya lecithin and antioxidant are added to the sunflower oil and mixed until homogenous.
  • the oil blend is added to the syrup mix and mixed in a dough mixer for 10 minutes.
  • the microalgal oil is added and further mixed for 5 minutes. All the remaining ingredients are added and further mixed for 10 minutes. Then the mass is rolled out, cooled down to 20°C and formed into bars.
  • a powdered cold water/juice instant drink to be reconstituted by 32g powder in 150-200 ml cold water or fruit juice which has following profile: Recommended daily amount 32g
  • composition pea protein 19.0% sucrose 32.36% inulin 13.8% encapsulated fish oil, BASF 8.6% maltodextrin DE20 9.6% banana powder 5.0% oat fiber 4.0% calcium lactate, soluble 3.32 banana flavour 1.6%
  • maltodextrin DE20 48.664 % iron-lll-pyrophosphate 39.46% selenium yeast 1000 6.5% zinc sulphate 5.35% potassium iodide 0.026%
  • Vitamin K powder 5% 0.15%
  • Vitamin E acetate 50% 8.3%
  • Vitamin A acetate 325 4.8%
  • Vitamin B 2 0.42%
  • Vitamin B 12 1 % 0.073%
  • VM (as in Example 1 ) 0.5% fructo-oligosaccharides 3.0% microalgae oil DHASCO, Martek Biosciences Corporation 1.0% sodium carbonate 0.2% vanilla 0.3% soya lecithin 0.4% antioxidant vit E 0.01 %

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

L'invention concerne une composition nutritionnelle pour femmes enceintes et allaitantes, cette composition renfermant: une source protéique non dérivée du lait; une fibre alimentaire et/ou une substance fibreuse; une source d'acides gras polyinsaturés; et des minéraux et des vitamines recommandés aux femmes enceintes et allaitantes. Cette composition est exempte de lactose et renferme moins de 2 %, en poids des composants secs de cette composition, de lait ou de produits dérivés du lait.
PCT/EP1999/002668 1998-04-22 1999-04-20 Complement nutritionnel pour femmes enceintes et allaitantes WO1999053777A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU37094/99A AU3709499A (en) 1998-04-22 1999-04-20 Nutritional supplement for pregnant and lactating women

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9808579.8A GB9808579D0 (en) 1998-04-22 1998-04-22 Improvements in or relating to organic compounds
GB9808579.8 1998-04-22

Publications (1)

Publication Number Publication Date
WO1999053777A1 true WO1999053777A1 (fr) 1999-10-28

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/002668 WO1999053777A1 (fr) 1998-04-22 1999-04-20 Complement nutritionnel pour femmes enceintes et allaitantes

Country Status (3)

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AU (1) AU3709499A (fr)
GB (1) GB9808579D0 (fr)
WO (1) WO1999053777A1 (fr)

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EP1155620A1 (fr) * 2000-05-18 2001-11-21 SportsCom Danmark ApS Composition nutritive comme suppléments diététiques
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WO2002052954A2 (fr) * 2001-01-08 2002-07-11 Societe Des Produits Nestle S.A. Composition nutritionnelle destinee a une pathologie osseuse
EP1330957A2 (fr) * 2002-01-15 2003-07-30 Karl-Heinz Bauer Supplement nutritive
WO2004091317A1 (fr) * 2003-04-17 2004-10-28 Boehringer Ingelheim International Gmbh Supplement multivitamines/mineraux pour femmes enceintes
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FR2864426A1 (fr) * 2003-12-29 2005-07-01 Arandi Complement alimentaire destine a combler les deficits nutritionnels
WO2005122791A2 (fr) * 2004-06-22 2005-12-29 N.V. Nutricia Amelioration de l'integrite de la barriere intestinale chez les patients atteints de vih
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WO2007105945A3 (fr) * 2006-03-10 2007-11-08 Nutricia Nv Utilisation de saccharides non digestibles pour assurer à un nouveau-né le meilleur départ dans la vie
GB2438157A (en) * 2006-05-18 2007-11-21 Emma Derbyshire Fortified drink for pregnant or postpartum mothers
US7560447B2 (en) 2000-05-08 2009-07-14 N.V. Nutricia Preparation for the prevention and/or treatment of vascular disorders
WO2009153065A1 (fr) 2008-06-19 2009-12-23 N.V. Nutricia Composition nutritionnelle pour patients de chirurgie bariatrique
US20120027738A1 (en) * 2006-05-23 2012-02-02 Nestec S.A. Maternal supplement
FR2963725A1 (fr) * 2010-08-16 2012-02-17 Holymark Composition alimentaire pour prevenir et limiter la perte de masse musculaire, la perte de densite minerale osseuse et le declin cognitif, en particulier chez les personnes agees de 50 ans et plus
US8168611B1 (en) 2011-09-29 2012-05-01 Chemo S.A. France Compositions, kits and methods for nutrition supplementation
US8183227B1 (en) 2011-07-07 2012-05-22 Chemo S. A. France Compositions, kits and methods for nutrition supplementation
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EP2508193A1 (fr) * 2011-04-05 2012-10-10 Nestec S.A. Utilisation de composition de céréale hypoallergénique pour induire une tolérance orale spécifique
US8372442B2 (en) 2008-06-19 2013-02-12 N.V. Nutricia Liquid nutritional composition for bariatric surgery patients
EP2597958A1 (fr) 2010-07-28 2013-06-05 Dawn Foods B.V. Agent de glaçage pour produits de boulangerie
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US9084433B2 (en) 2004-06-06 2015-07-21 N. V. Nutricia Intestinal barrier integrity
US20160198748A1 (en) * 2013-05-28 2016-07-14 Purecircle Sdn Bhd High-Purity Steviol Glycosides
EP2403352B1 (fr) * 2009-03-02 2017-03-15 Roquette Freres Poudre granulée contenant des protéines végétales et des fibres, leur procédé d'obtention et leurs utilisations
EP3323296A1 (fr) * 2016-11-16 2018-05-23 Maresol GmbH & Co. KG Chocolat avec éléments nutritifs ajoutés et procédé de fabrication d'un chocolat
US10426791B2 (en) 2004-05-17 2019-10-01 N.V. Nutricia Synergism of GOS and polyfructose
CN111165812A (zh) * 2020-03-31 2020-05-19 中国农业大学 一种基于豌豆蛋白的针对过敏人群的全营养配方食品
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WO2021005088A1 (fr) * 2019-07-11 2021-01-14 Société des Produits Nestlé S.A. Compositions alimentaires pour la gestion du poids
EP3771342A1 (fr) * 2019-07-31 2021-02-03 Lactalis Puleva, S.L. Produit laitier buvable pour femmes enceintes et allaitantes
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US11206841B2 (en) 2016-09-09 2021-12-28 International Agriculture Group, LLC Yogurt product from high starch fruits
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CN114340407A (zh) * 2019-09-05 2022-04-12 雀巢产品有限公司 用于哺乳女性的食物组合物
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