WO1999042621A3 - Proprietes thermodynamiques d'acides nucleiques - Google Patents

Proprietes thermodynamiques d'acides nucleiques Download PDF

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Publication number
WO1999042621A3
WO1999042621A3 PCT/US1999/003754 US9903754W WO9942621A3 WO 1999042621 A3 WO1999042621 A3 WO 1999042621A3 US 9903754 W US9903754 W US 9903754W WO 9942621 A3 WO9942621 A3 WO 9942621A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
identifying
methods
characterising
site based
Prior art date
Application number
PCT/US1999/003754
Other languages
English (en)
Other versions
WO1999042621A2 (fr
Inventor
Michael J Lane
Albert S Benight
Brian D Faldasz
Original Assignee
Tm Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tm Technologies Inc filed Critical Tm Technologies Inc
Priority to AU33049/99A priority Critical patent/AU3304999A/en
Publication of WO1999042621A2 publication Critical patent/WO1999042621A2/fr
Publication of WO1999042621A3 publication Critical patent/WO1999042621A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G16B30/10—Sequence alignment; Homology search
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/30—Detection of binding sites or motifs
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Cette invention concerne des séquences d'acides nucléiques, et, plus particulièrement, des procédés permettant d'identifier ou de définir des caractéristiques structurales et/ou énergétiques pour des acides nucléiques, et des protéines qui sont codées par lesdits acides nucléiques.
PCT/US1999/003754 1998-02-21 1999-02-19 Proprietes thermodynamiques d'acides nucleiques WO1999042621A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU33049/99A AU3304999A (en) 1998-02-21 1999-02-19 Thermodynamic properties of nucleic acids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7563398P 1998-02-21 1998-02-21
US60/075,633 1998-02-21

Publications (2)

Publication Number Publication Date
WO1999042621A2 WO1999042621A2 (fr) 1999-08-26
WO1999042621A3 true WO1999042621A3 (fr) 2000-03-16

Family

ID=22127047

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/003754 WO1999042621A2 (fr) 1998-02-21 1999-02-19 Proprietes thermodynamiques d'acides nucleiques

Country Status (2)

Country Link
AU (1) AU3304999A (fr)
WO (1) WO1999042621A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063074A2 (fr) * 1998-06-04 1999-12-09 Tm Technologies, Inc. Methode permettant de modifier le niveau d'expression relatif d'un quelconque gene; procedes et produits connexes
GB2356401A (en) 1999-11-19 2001-05-23 Proteom Ltd Method for manipulating protein or DNA sequence data

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993000446A1 (fr) * 1991-06-27 1993-01-07 Genelabs Technologies, Inc. Methode de tri pour la detection de molecules de liaison d'adn
WO1995000665A1 (fr) * 1993-06-17 1995-01-05 The Research Foundation Of State University Of New York Thermodynamique, conception et utilisation de sequences d'acides nucleiques
WO1998037242A1 (fr) * 1997-02-24 1998-08-27 Tm Technologies, Inc. Procede de selection d'oligonucleotides antisens
WO1999032664A1 (fr) * 1997-12-23 1999-07-01 Tm Technologies, Inc. Procede de selection de sequences adjacentes porteuses d'affinites de liaison relatives a un site de liaison aux ligands

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993000446A1 (fr) * 1991-06-27 1993-01-07 Genelabs Technologies, Inc. Methode de tri pour la detection de molecules de liaison d'adn
WO1995000665A1 (fr) * 1993-06-17 1995-01-05 The Research Foundation Of State University Of New York Thermodynamique, conception et utilisation de sequences d'acides nucleiques
WO1998037242A1 (fr) * 1997-02-24 1998-08-27 Tm Technologies, Inc. Procede de selection d'oligonucleotides antisens
WO1999032664A1 (fr) * 1997-12-23 1999-07-01 Tm Technologies, Inc. Procede de selection de sequences adjacentes porteuses d'affinites de liaison relatives a un site de liaison aux ligands

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
ANTISENSE RES.DEV., vol. 3, no. 1, 1993, pages 45 - 52 *
BIOTECHNIQUES, vol. 20, no. 6, June 1996 (1996-06-01), pages 1090 - 1097 *
BRUICE T W ET AL: "Control of complexity constraints on combinatorial screening for preferred oligonucleotide hybridisation sites on structured RNA", BIOCHEMISTRY,US,AMERICAN CHEMICAL SOCIETY. EASTON, PA, vol. 36, no. 16, pages 5004-5019-5019, XP002110003, ISSN: 0006-2960 *
DATABASE CHEMABS Chemical Abstracts Service, Columbus, Ohio, US; STULL, R.A. ET AL.: "Predicting antisense oligonucleotide inhibitory efficacy: a computational approach using histograms and thermodynamic indices", XP002110007 *
DATABASE CHEMICAL ABSTRACTS 18 August 1997 (1997-08-18), SCZAKIEL G. ET AL.: "Computer-aided calculation of the local folding potential of target RNA and its use for ribozyme design", XP002110004 *
DATABASE CHEMICAL ABSTRACTS SZAKIEL G. ET AL.: "Computer-aided search for effective antisense RNA target sequences of the human immunodeficiency virus type 1", XP002110005 *
DATABASE MEDLINE us national library of medicine; HYNDMAN D. ET AL.: "Software to detewrmine optimal oligonucleotide sequences based on hybridization simulation data", XP002110006 *
METHODS MOL. BIOL., vol. 74, 1997, US, pages 11 - 15 *
NUCLEIC ACIDS RES., vol. 20, no. 13, 1992, pages 3501 - 3508 *

Also Published As

Publication number Publication date
AU3304999A (en) 1999-09-06
WO1999042621A2 (fr) 1999-08-26

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