WO1999051744A3 - Antagoniste du recepteur de l'interleukine-1 et ses utilisations - Google Patents

Antagoniste du recepteur de l'interleukine-1 et ses utilisations Download PDF

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Publication number
WO1999051744A3
WO1999051744A3 PCT/US1999/004291 US9904291W WO9951744A3 WO 1999051744 A3 WO1999051744 A3 WO 1999051744A3 US 9904291 W US9904291 W US 9904291W WO 9951744 A3 WO9951744 A3 WO 9951744A3
Authority
WO
WIPO (PCT)
Prior art keywords
interleukin
receptor antagonist
nucleic acids
polypeptide sequences
polynucleotide
Prior art date
Application number
PCT/US1999/004291
Other languages
English (en)
Other versions
WO1999051744A2 (fr
Inventor
John Ford
Ann Pace
Original Assignee
Hyseq Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hyseq Inc filed Critical Hyseq Inc
Priority to JP2000542457A priority Critical patent/JP2002510492A/ja
Priority to CA002326066A priority patent/CA2326066A1/fr
Priority to EP99916115A priority patent/EP1068321A2/fr
Priority to AU34495/99A priority patent/AU769262B2/en
Priority to IL13857699A priority patent/IL138576A0/xx
Priority to US09/348,942 priority patent/US6337072B1/en
Publication of WO1999051744A2 publication Critical patent/WO1999051744A2/fr
Publication of WO1999051744A3 publication Critical patent/WO1999051744A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention porte sur de nouveaux acides nucléiques, sur les nouvelles séquences de polypeptides codées par eux, et sur leurs utilisations. Ces nouveaux polynucléotides et ces nouvelles séquences de polypeptides se sont avérées constituer un nouvel antagoniste du récepteur de l'interleukine-1.
PCT/US1999/004291 1998-04-03 1999-04-05 Antagoniste du recepteur de l'interleukine-1 et ses utilisations WO1999051744A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2000542457A JP2002510492A (ja) 1998-04-03 1999-04-05 インターロイキン−１レセプターアンタゴニストおよびその使用
CA002326066A CA2326066A1 (fr) 1998-04-03 1999-04-05 Antagoniste du recepteur de l'interleukine-1 et ses utilisations
EP99916115A EP1068321A2 (fr) 1998-04-03 1999-04-05 Antagoniste du recepteur de l'interleukine-1 et ses utilisations
AU34495/99A AU769262B2 (en) 1998-04-03 1999-04-05 A interleukin-1 receptor antagonist and uses thereof
IL13857699A IL138576A0 (en) 1998-04-03 1999-04-05 A novel interleukin-1 receptor antagonist and uses thereof
US09/348,942 US6337072B1 (en) 1998-04-03 1999-07-07 Interleukin-1 receptor antagonist and recombinant production thereof

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US5501098A 1998-04-03 1998-04-03
US7990998A 1998-05-15 1998-05-15
US8236498A 1998-05-20 1998-05-20
US9981898A 1998-06-19 1998-06-19
US12769898A 1998-07-31 1998-07-31
US22959199A 1999-01-13 1999-01-13
US25137099A 1999-02-17 1999-02-17
US09/079,909 1999-02-17
US09/055,010 1999-02-17
US09/127,698 1999-02-17
US09/099,818 1999-02-17
US09/082,364 1999-02-17
US09/229,591 1999-02-17
US09/251,370 1999-02-17

Publications (2)

Publication Number Publication Date
WO1999051744A2 WO1999051744A2 (fr) 1999-10-14
WO1999051744A3 true WO1999051744A3 (fr) 2000-03-30

Family

ID=27568093

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/004291 WO1999051744A2 (fr) 1998-04-03 1999-04-05 Antagoniste du recepteur de l'interleukine-1 et ses utilisations

Country Status (6)

Country Link
EP (1) EP1068321A2 (fr)
JP (1) JP2002510492A (fr)
AU (1) AU769262B2 (fr)
CA (1) CA2326066A1 (fr)
IL (1) IL138576A0 (fr)
WO (1) WO1999051744A2 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ505881A (en) 1998-01-09 2003-05-30 Immunex Corp IL-1 delta DNA and polypeptides
US6541623B1 (en) * 1998-04-03 2003-04-01 Hyseq, Inc. Interleukin—1 receptor antagonist and uses thereof
AU6296899A (en) * 1998-10-08 2000-04-26 Zymogenetics Inc. Interleukin-1 homolog
IL143593A0 (en) 1998-12-23 2002-04-21 Genentech Inc Il-1 related polypeptides
US6339141B1 (en) 1999-05-20 2002-01-15 Hycey Inc. Interleukin-1 Hy2 materials and methods
ES2300266T3 (es) * 1999-05-20 2008-06-16 Nuvelo, Inc. Interleuquina-1 hy2, materiales y metodos.
US6627199B1 (en) 1999-07-09 2003-09-30 Amgen Inc Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family
IL147534A0 (en) * 1999-07-16 2002-08-14 Interleukin Genetics Inc The il-il1 gene and polypeptide products
AU783682B2 (en) 1999-08-04 2005-11-24 Amgen, Inc. Fhm, a novel member of the TNF ligand supergene family
WO2001010908A1 (fr) 1999-08-04 2001-02-15 Amgen Inc. Ntr3, membre de la famille de supergenes recepteurs du tnf
WO2001089549A2 (fr) * 2000-05-22 2001-11-29 Hyseq, Inc. Utilisations therapeutiques d'antagoniste du recepteur de l'il-1
US20030099650A1 (en) * 2001-07-25 2003-05-29 Ho Alice Suk-Yue Treatment of immune disorders and B cell disorders
EP1737481A4 (fr) * 2004-02-27 2008-04-02 Vaxconsulting Peptides de il1 beta et tnf alpha et methode de traitement comprenant l'utilisation de ceux-ci
WO2009062339A1 (fr) 2007-11-14 2009-05-22 General Regeneratives, Ltd. Procédés d'utilisation d'un antagoniste des récepteurs de l'interleukine 1 en tant qu'un agent myéloprotecteur
CN101690801B (zh) 2009-10-26 2012-08-01 上海交通大学 白细胞介素-1受体拮抗剂的用途及其药物组合物
WO2015191783A2 (fr) 2014-06-10 2015-12-17 Abbvie Inc. Biomarqueurs des maladies inflammatoires et leurs procédés d'utilisation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991017249A1 (fr) * 1990-05-01 1991-11-14 Cetus Corporation Antagoniste d'interleucine-1 et utilisation de celui-ci
WO1998047921A1 (fr) * 1997-04-21 1998-10-29 Schering Corporation Cytokines de mammifere; reactifs et procedes connexes
WO1999035268A1 (fr) * 1998-01-09 1999-07-15 Immunex Corporation Adn codant il-1 delta et polypeptides il-1 delta

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148009B1 (ko) 1988-05-27 1998-08-01 그래고리 비. 아보트 인터루킨-1 억제제

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991017249A1 (fr) * 1990-05-01 1991-11-14 Cetus Corporation Antagoniste d'interleucine-1 et utilisation de celui-ci
WO1998047921A1 (fr) * 1997-04-21 1998-10-29 Schering Corporation Cytokines de mammifere; reactifs et procedes connexes
WO1999035268A1 (fr) * 1998-01-09 1999-07-15 Immunex Corporation Adn codant il-1 delta et polypeptides il-1 delta

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J.J. MULERO ET AL: "iL-1HY1: A novel Interleukin-1 Receptor Antagonist gene", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 263, no. 3, 5 October 1999 (1999-10-05), ACADEMIC PRESS INC. ORLANDO, FL., US, pages 702 - 706, XP002126222, ISSN: 0006-291X *

Also Published As

Publication number Publication date
CA2326066A1 (fr) 1999-10-14
AU3449599A (en) 1999-10-25
WO1999051744A2 (fr) 1999-10-14
AU769262B2 (en) 2004-01-22
EP1068321A2 (fr) 2001-01-17
IL138576A0 (en) 2001-10-31
JP2002510492A (ja) 2002-04-09

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