WO1999041375A3 - Human receptor proteins - Google Patents

Human receptor proteins Download PDF

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Publication number
WO1999041375A3
WO1999041375A3 PCT/US1999/002572 US9902572W WO9941375A3 WO 1999041375 A3 WO1999041375 A3 WO 1999041375A3 US 9902572 W US9902572 W US 9902572W WO 9941375 A3 WO9941375 A3 WO 9941375A3
Authority
WO
WIPO (PCT)
Prior art keywords
receptor proteins
human receptor
hurp
provides
expression
Prior art date
Application number
PCT/US1999/002572
Other languages
French (fr)
Other versions
WO1999041375A2 (en
Inventor
Jennifer L Hillman
Olga Bandman
Henry Yue
Karl J Guegler
Neil C Corley
Janice Au-Young
Y Tom Tang
Purvi Shah
Preeti Lal
Mariah Baughn
Original Assignee
Incyte Pharma Inc
Jennifer L Hillman
Olga Bandman
Henry Yue
Karl J Guegler
Neil C Corley
Au Young Janice
Y Tom Tang
Purvi Shah
Preeti Lal
Mariah Baughn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Jennifer L Hillman, Olga Bandman, Henry Yue, Karl J Guegler, Neil C Corley, Au Young Janice, Y Tom Tang, Purvi Shah, Preeti Lal, Mariah Baughn filed Critical Incyte Pharma Inc
Priority to CA002320427A priority Critical patent/CA2320427A1/en
Priority to JP2000531556A priority patent/JP2002503465A/en
Priority to AU26597/99A priority patent/AU2659799A/en
Priority to EP99906764A priority patent/EP1053323A2/en
Publication of WO1999041375A2 publication Critical patent/WO1999041375A2/en
Publication of WO1999041375A3 publication Critical patent/WO1999041375A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention provides human receptor proteins (HURP) and polynucleotides which identify and encode HURP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HURP.
PCT/US1999/002572 1998-02-12 1999-02-05 Human receptor proteins WO1999041375A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002320427A CA2320427A1 (en) 1998-02-12 1999-02-05 Human receptor proteins
JP2000531556A JP2002503465A (en) 1998-02-12 1999-02-05 Human receptor protein
AU26597/99A AU2659799A (en) 1998-02-12 1999-02-05 Human receptor proteins
EP99906764A EP1053323A2 (en) 1998-02-12 1999-02-05 Human receptor proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2293998A 1998-02-12 1998-02-12
US09/022,939 1998-02-12

Publications (2)

Publication Number Publication Date
WO1999041375A2 WO1999041375A2 (en) 1999-08-19
WO1999041375A3 true WO1999041375A3 (en) 1999-12-16

Family

ID=21812214

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/002572 WO1999041375A2 (en) 1998-02-12 1999-02-05 Human receptor proteins

Country Status (5)

Country Link
EP (1) EP1053323A2 (en)
JP (1) JP2002503465A (en)
AU (1) AU2659799A (en)
CA (1) CA2320427A1 (en)
WO (1) WO1999041375A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000008155A2 (en) * 1998-08-07 2000-02-17 Incyte Pharmaceuticals, Inc. Human receptor-associated proteins
AUPQ051099A0 (en) * 1999-05-24 1999-06-17 Tachas, George Dr Novel products and processes in treatment and/or prophylaxis
DE10211088A1 (en) * 2002-03-13 2003-09-25 Ugur Sahin Gene products differentially expressed in tumors and their use
DE10341812A1 (en) 2003-09-10 2005-04-07 Ganymed Pharmaceuticals Ag Differentially expressed in tumors gene products and their use

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996004928A1 (en) * 1994-08-16 1996-02-22 Human Genome Sciences, Inc. Calcitonin gene related peptide receptor
WO1996040040A2 (en) * 1995-06-06 1996-12-19 Incyte Pharmaceuticals, Inc. Thrombin receptor homolog
WO1997000952A2 (en) * 1995-06-20 1997-01-09 Incyte Pharmaceuticals, Inc. A human edg-2 receptor homolog

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996004928A1 (en) * 1994-08-16 1996-02-22 Human Genome Sciences, Inc. Calcitonin gene related peptide receptor
WO1996040040A2 (en) * 1995-06-06 1996-12-19 Incyte Pharmaceuticals, Inc. Thrombin receptor homolog
WO1997000952A2 (en) * 1995-06-20 1997-01-09 Incyte Pharmaceuticals, Inc. A human edg-2 receptor homolog

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ADAMS M D ET AL: "INITIAL ASSESSMENT OF HUMAN GENE DIVERSITY AND EXPRESSION PATTERNS BASED UPON 83 MILLION NUCLEOTIDES OF CDNA SEQUENCE", NATURE, vol. 377, no. SUPPL, 28 September 1995 (1995-09-28), pages 3 - 17, XP002069461 *
DATABASE EMBL - EMEST17 18 April 1997 (1997-04-18), ADAMS, M.D. ET AL.: "EST178143 Colon carcinoma (HCC) cell line Homo sapiens cDNA 5' end similar to similar to ligatin.", XP002108160 *
DATABASE EMBL - EMROD 28 June 1996 (1996-06-28), MALNAR-DRAGOJEVIC, D. ET AL.: "Mus musculus ligatin (Lgtn) mRNA, partial cds.", XP002108158 *
DATABASE EMBL - R57U019 18 April 1997 (1997-04-18), STRAUSBERG, R.: "ai01e08.s1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone IMAGE:1327334 3' similar to TR:Q61211 Q61211 LIGATIN ;, mRNA sequence.", XP002108159 *
JAKOI, E.R. ET AL.: "Molecular cloning of the cDNA for ligatin.", JOURNAL OF CELL SCIENCE, vol. 93, no. 2, June 1989 (1989-06-01), pages 227 - 32, XP002108156 *
MALNAR-DRAGOJEVIC, D. ET AL.: "Assignment of the mouse ligatin gene (Lgtn) to chromosome 1F by in situ hybridization.", GENOMICS, vol. 40, no. 1, 15 February 1997 (1997-02-15), pages 192 - 3, XP002108157 *
Y YOSHIKAI ET AL: "Sequence and expression of transcripts of the human T-cell receptor beta-chain genes", NATURE, vol. 312, 6 December 1984 (1984-12-06), pages 521 - 524, XP002084031 *

Also Published As

Publication number Publication date
CA2320427A1 (en) 1999-08-19
WO1999041375A2 (en) 1999-08-19
AU2659799A (en) 1999-08-30
JP2002503465A (en) 2002-02-05
EP1053323A2 (en) 2000-11-22

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