WO1999021538A3 - Use of glycosaminoglycans for producing pharmaceutical preparations for treating diabetes-associated diseases of the eye - Google Patents

Use of glycosaminoglycans for producing pharmaceutical preparations for treating diabetes-associated diseases of the eye Download PDF

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Publication number
WO1999021538A3
WO1999021538A3 PCT/EP1998/006703 EP9806703W WO9921538A3 WO 1999021538 A3 WO1999021538 A3 WO 1999021538A3 EP 9806703 W EP9806703 W EP 9806703W WO 9921538 A3 WO9921538 A3 WO 9921538A3
Authority
WO
WIPO (PCT)
Prior art keywords
eye
pharmaceutical preparations
glycosaminoglycans
treating diabetes
associated diseases
Prior art date
Application number
PCT/EP1998/006703
Other languages
German (de)
French (fr)
Other versions
WO1999021538A2 (en
Inventor
DER WOUDE Fokko VAN
Dieter Herr
Volker Laux
Original Assignee
Knoll Ag
Woude Fokko V D
Dieter Herr
Volker Laux
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag, Woude Fokko V D, Dieter Herr, Volker Laux filed Critical Knoll Ag
Priority to KR1020007004363A priority Critical patent/KR20010024550A/en
Priority to HU0004647A priority patent/HUP0004647A3/en
Priority to BR9813098-6A priority patent/BR9813098A/en
Priority to JP2000517697A priority patent/JP2001520987A/en
Priority to EP98956862A priority patent/EP1047434A2/en
Priority to AU13355/99A priority patent/AU749673B2/en
Priority to CA002306379A priority patent/CA2306379A1/en
Priority to IL13517198A priority patent/IL135171A0/en
Publication of WO1999021538A2 publication Critical patent/WO1999021538A2/en
Publication of WO1999021538A3 publication Critical patent/WO1999021538A3/en
Priority to NO20001895A priority patent/NO20001895D0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Abstract

The invention relates to the use of glycosaminoglycans for producing pharmaceutical preparations for preventing or treating diseases of the eye which are associated with diabetes. The invention also relates to pharmaceutical preparations which are suitable for preventing or treating diseases of the eye associated with diabetes.
PCT/EP1998/006703 1997-10-24 1998-10-22 Use of glycosaminoglycans for producing pharmaceutical preparations for treating diabetes-associated diseases of the eye WO1999021538A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
KR1020007004363A KR20010024550A (en) 1997-10-24 1998-10-22 Use of Glycosaminoglycans for Producing Pharmaceutical Preparations for Treating Diabetes-Associated Diseases of the Eye
HU0004647A HUP0004647A3 (en) 1997-10-24 1998-10-22 Use of glycosaminoglycans for producing pharmaceutical preparations for treating diabetes-associated diseases of the eye
BR9813098-6A BR9813098A (en) 1997-10-24 1998-10-22 Use of glycosaminoglycans, pharmaceutical preparation, and combination
JP2000517697A JP2001520987A (en) 1997-10-24 1998-10-22 Use of glycosaminoglycans for the manufacture of a pharmaceutical formulation for the treatment of eye diseases associated with diabetes
EP98956862A EP1047434A2 (en) 1997-10-24 1998-10-22 Use of glycosaminoglycans for producing pharmaceutical preparations for treating diabetes-associated diseases of the eye
AU13355/99A AU749673B2 (en) 1997-10-24 1998-10-22 Use of glycosaminoglycans for producing pharmaceutical preparations for treating diabetes-associated diseases of the eye
CA002306379A CA2306379A1 (en) 1997-10-24 1998-10-22 Use of glycosaminoglycans for producing pharmaceutical preparations for treating diabetes-associated diseases of the eye
IL13517198A IL135171A0 (en) 1997-10-24 1998-10-22 Use of glycosaminoglycans for producing pharmaceutical preparations for treating diabetes-associated diseases of the eye
NO20001895A NO20001895D0 (en) 1997-10-24 2000-04-12 Use of glycosaminoglycans for the preparation of pharmaceutical preparations for the treatment of diabetes-associated eye diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19747195.1 1997-10-24
DE19747195A DE19747195A1 (en) 1997-10-24 1997-10-24 Compositions for treating diabetic retinopathy

Publications (2)

Publication Number Publication Date
WO1999021538A2 WO1999021538A2 (en) 1999-05-06
WO1999021538A3 true WO1999021538A3 (en) 1999-08-05

Family

ID=7846613

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/006703 WO1999021538A2 (en) 1997-10-24 1998-10-22 Use of glycosaminoglycans for producing pharmaceutical preparations for treating diabetes-associated diseases of the eye

Country Status (13)

Country Link
EP (1) EP1047434A2 (en)
JP (1) JP2001520987A (en)
KR (1) KR20010024550A (en)
CN (1) CN1277554A (en)
AU (1) AU749673B2 (en)
BR (1) BR9813098A (en)
CA (1) CA2306379A1 (en)
DE (1) DE19747195A1 (en)
HU (1) HUP0004647A3 (en)
IL (1) IL135171A0 (en)
NO (1) NO20001895D0 (en)
WO (1) WO1999021538A2 (en)
ZA (1) ZA989665B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI991503A1 (en) * 1999-07-08 2001-01-08 Bidifarm S R L USE OF PROTEOGYLICAN OLIGOSACCHARIDIC METABOLITES AS MAKER IN BIOLOGICAL FLUIDS FOR DIAGNOSIS OF BIABET AND PATHOLOGICAL COMPLICATIONS C
CN101584704B (en) * 2008-05-23 2010-12-15 鲁南制药集团股份有限公司 Medicinal application of medicinal salt or derivative of heparin and low molecular heparin
JPWO2011122321A1 (en) * 2010-03-29 2013-07-08 国立大学法人名古屋大学 Bioactivity inhibitors for heparin-binding proteins
CN107137421A (en) * 2017-05-25 2017-09-08 青岛市中心医院 Dextran sulfate is preparing the application in suppressing corneal vascularization medicine

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244298A2 (en) * 1986-04-17 1987-11-04 Sanofi Oligosaccharides of heparin having an affinity for cell growth factors
WO1990000058A1 (en) * 1988-06-27 1990-01-11 Roland Reiner Glycosaminoglycane for the treatment of diabetic microangiopathy
EP0394971A1 (en) * 1989-04-24 1990-10-31 Kabi Pharmacia Ab Oligosaccharide-containing inhibitors of endothelial cell growth and angiogenesis
US5135920A (en) * 1988-11-16 1992-08-04 Takeda Chemical Industries, Ltd. Angiostatic agents
WO1995005182A1 (en) * 1993-08-13 1995-02-23 Glycomed Incorporated Bridged oligosaccharides and sulfated derivatives thereof
WO1995009637A1 (en) * 1993-10-07 1995-04-13 Glycomed Incorporated Highly sulfated maltooligosaccharides with heparin-like properties
WO1996040158A1 (en) * 1995-06-07 1996-12-19 Baker Norton Pharmaceuticals, Inc. Method of treating chronic progressive vascular diseases
WO1999004801A1 (en) * 1997-07-28 1999-02-04 Rijks Universiteit Leiden Use of sulfated glycosaminoglycans for treating of retinopathy

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0244298A2 (en) * 1986-04-17 1987-11-04 Sanofi Oligosaccharides of heparin having an affinity for cell growth factors
WO1990000058A1 (en) * 1988-06-27 1990-01-11 Roland Reiner Glycosaminoglycane for the treatment of diabetic microangiopathy
US5135920A (en) * 1988-11-16 1992-08-04 Takeda Chemical Industries, Ltd. Angiostatic agents
EP0394971A1 (en) * 1989-04-24 1990-10-31 Kabi Pharmacia Ab Oligosaccharide-containing inhibitors of endothelial cell growth and angiogenesis
WO1995005182A1 (en) * 1993-08-13 1995-02-23 Glycomed Incorporated Bridged oligosaccharides and sulfated derivatives thereof
WO1995009637A1 (en) * 1993-10-07 1995-04-13 Glycomed Incorporated Highly sulfated maltooligosaccharides with heparin-like properties
WO1996040158A1 (en) * 1995-06-07 1996-12-19 Baker Norton Pharmaceuticals, Inc. Method of treating chronic progressive vascular diseases
WO1999004801A1 (en) * 1997-07-28 1999-02-04 Rijks Universiteit Leiden Use of sulfated glycosaminoglycans for treating of retinopathy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
P. DI GIACOMO ET AL: "Efficacia terapeutica dell'eparansolfato nella retinopatia diabetica incipente", QUAD.MED.CHIR, vol. 11, no. 3, 1995, pages 370 - 373, XP002096378 *

Also Published As

Publication number Publication date
HUP0004647A3 (en) 2002-01-28
AU749673B2 (en) 2002-07-04
EP1047434A2 (en) 2000-11-02
NO20001895L (en) 2000-04-12
WO1999021538A2 (en) 1999-05-06
NO20001895D0 (en) 2000-04-12
DE19747195A1 (en) 1999-04-29
ZA989665B (en) 2000-04-25
CA2306379A1 (en) 1999-05-06
JP2001520987A (en) 2001-11-06
HUP0004647A2 (en) 2001-05-28
CN1277554A (en) 2000-12-20
IL135171A0 (en) 2001-05-20
BR9813098A (en) 2000-08-15
KR20010024550A (en) 2001-03-26
AU1335599A (en) 1999-05-17

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