WO1999011791A3 - Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents - Google Patents

Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents Download PDF

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Publication number
WO1999011791A3
WO1999011791A3 PCT/US1998/018393 US9818393W WO9911791A3 WO 1999011791 A3 WO1999011791 A3 WO 1999011791A3 US 9818393 W US9818393 W US 9818393W WO 9911791 A3 WO9911791 A3 WO 9911791A3
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WIPO (PCT)
Prior art keywords
ligands
necrosis factor
tumor necrosis
nucleic acids
binding agents
Prior art date
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PCT/US1998/018393
Other languages
French (fr)
Other versions
WO1999011791A2 (en
Inventor
Preet M Chaudhary
Original Assignee
Univ Washington
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Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Priority to AU93764/98A priority Critical patent/AU9376498A/en
Publication of WO1999011791A2 publication Critical patent/WO1999011791A2/en
Publication of WO1999011791A3 publication Critical patent/WO1999011791A3/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention provides novel receptors of the tumor necrosis factor receptor family as well as ligands of the tumor necrosis factor family. In addition to the isolated receptors and ligands of the invention, there are provided encoding nucleic acids and related selective binding agents.
PCT/US1998/018393 1997-09-05 1998-09-04 Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents WO1999011791A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU93764/98A AU9376498A (en) 1997-09-05 1998-09-04 Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92463497A 1997-09-05 1997-09-05
US08/924,634 1997-09-05

Publications (2)

Publication Number Publication Date
WO1999011791A2 WO1999011791A2 (en) 1999-03-11
WO1999011791A3 true WO1999011791A3 (en) 1999-09-30

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PCT/US1998/018393 WO1999011791A2 (en) 1997-09-05 1998-09-04 Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents

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AU (1) AU9376498A (en)
WO (1) WO1999011791A2 (en)

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US9187548B2 (en) 2000-06-16 2015-11-17 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to B lymphocyte stimulator protein
US9017671B2 (en) 2004-10-20 2015-04-28 Genentech, Inc. Method of treating cancer with a pharmaceutical formulation comprising a HER2 antibody

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