WO1998054575A3 - Method for assessing wound healing - Google Patents

Method for assessing wound healing Download PDF

Info

Publication number
WO1998054575A3
WO1998054575A3 PCT/GB1998/001520 GB9801520W WO9854575A3 WO 1998054575 A3 WO1998054575 A3 WO 1998054575A3 GB 9801520 W GB9801520 W GB 9801520W WO 9854575 A3 WO9854575 A3 WO 9854575A3
Authority
WO
WIPO (PCT)
Prior art keywords
healing
wound healing
wound
assessing
healing status
Prior art date
Application number
PCT/GB1998/001520
Other languages
French (fr)
Other versions
WO1998054575A2 (en
Inventor
Keith Moore
Original Assignee
Univ Wales Medicine
Keith Moore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wales Medicine, Keith Moore filed Critical Univ Wales Medicine
Priority to CA002289690A priority Critical patent/CA2289690A1/en
Priority to AU75430/98A priority patent/AU7543098A/en
Priority to JP50036399A priority patent/JP2002512692A/en
Priority to EP98922971A priority patent/EP0986760A2/en
Publication of WO1998054575A2 publication Critical patent/WO1998054575A2/en
Publication of WO1998054575A3 publication Critical patent/WO1998054575A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Ecology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The present invention is directed to a method for assessing the healing status of a wound in a mammal, which method comprises measuring the amount of at least one lymphocyte cell membrane antigen present in a sample of body fluid or tissue. It has been found that the ratio of T-lymphocyte antigens CD4 and CD8 vary depending on the healing status of a wound. Assessment of the healing status assists in identifying the correct treatment to promote healing.
PCT/GB1998/001520 1997-05-27 1998-05-26 Method for assessing wound healing WO1998054575A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002289690A CA2289690A1 (en) 1997-05-27 1998-05-26 Method for assessing wound healing
AU75430/98A AU7543098A (en) 1997-05-27 1998-05-26 Method for assessing wound healing
JP50036399A JP2002512692A (en) 1997-05-27 1998-05-26 How to assess wound healing
EP98922971A EP0986760A2 (en) 1997-05-27 1998-05-26 Method for assessing wound healing

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATPCT/GB97/01439 1997-05-27
GB9701439 1997-05-27

Publications (2)

Publication Number Publication Date
WO1998054575A2 WO1998054575A2 (en) 1998-12-03
WO1998054575A3 true WO1998054575A3 (en) 1999-03-11

Family

ID=10806514

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1998/001520 WO1998054575A2 (en) 1997-05-27 1998-05-26 Method for assessing wound healing

Country Status (5)

Country Link
EP (1) EP0986760A2 (en)
JP (1) JP2002512692A (en)
AU (1) AU7543098A (en)
CA (1) CA2289690A1 (en)
WO (1) WO1998054575A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3312608B1 (en) * 2016-10-24 2019-10-02 Akribes Biomedical GmbH Methods for identifying a non-healing skin wound and for monitoring the healing of a skin wound

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677061A (en) * 1984-10-19 1987-06-30 Genetic Systems Corporation T-cell lymphocyte subset monitoring of immunologic disease
SU1516979A1 (en) * 1987-04-23 1989-10-23 Саратовский государственный медицинский институт )method of predicting the course of wound process of patients with purulent infection
WO1991007508A1 (en) * 1989-11-15 1991-05-30 National Jewish Center For Immunology And Respiratory Medicine Method for measuring t-cell surface antigens in humans
EP0559572A1 (en) * 1992-03-06 1993-09-08 Jean-Claude Donzeau Method for checking for immunity in humans by studying lymphocyte populations
WO1997011369A1 (en) * 1995-09-19 1997-03-27 Merck & Co., Inc. Method for quantitating an inflammatory response

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677061A (en) * 1984-10-19 1987-06-30 Genetic Systems Corporation T-cell lymphocyte subset monitoring of immunologic disease
SU1516979A1 (en) * 1987-04-23 1989-10-23 Саратовский государственный медицинский институт )method of predicting the course of wound process of patients with purulent infection
WO1991007508A1 (en) * 1989-11-15 1991-05-30 National Jewish Center For Immunology And Respiratory Medicine Method for measuring t-cell surface antigens in humans
EP0559572A1 (en) * 1992-03-06 1993-09-08 Jean-Claude Donzeau Method for checking for immunity in humans by studying lymphocyte populations
WO1997011369A1 (en) * 1995-09-19 1997-03-27 Merck & Co., Inc. Method for quantitating an inflammatory response

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Derwent World Patents Index; AN 90-138480, XP002079786 *
HANSBROUGH J F ET AL: "TEMPORAL ANALYSIS OF MURINE LYMPHOCYTE SUBPOPULATIONS BY MONOCLONAL ANTIBODIES AND DUAL-COLOR FLOW CYTOMETRY AFTER BURN AND NONBURN INJURY.", SURGERY (ST. LOUIS) 106 (1). 1989. 69-80. CODEN: SURGAZ ISSN: 0039-6060, XP002079784 *
MOORE K ET AL: "T LYMPHOCYTES AND THE LACK OF ACTIVATED MACROPHAGES IN WOUND MARGINBIOPSIES FROM CHRONIC LEG ULCERS", BRITISH JOURNAL OF DERMATOLOGY, vol. 137, no. 2, August 1997 (1997-08-01), pages 188 - 194, XP002054364 *
WOOD J J ET AL: "IMMATURE T LYMPHOCYTES AFTER INJURY CHARACTERIZED BY MORPHOLOGY AND PHENOTYPIC MARKERS.", ANN SURG 206 (5). 1987. 564-571. CODEN: ANSUA5 ISSN: 0003-4932, XP002079785 *
ZAPATA-SIRVENT R L ET AL: "TEMPORAL ANALYSIS OF HUMAN LEUCOCYTE SURFACE ANTIGEN EXPRESSION AND NEUTROPHIL RESPIRATORY BURST ACTIVITY AFTER THERMAL INJURY.", BURNS 19 (1). 1993. 5-11. CODEN: BURND8, XP002079783 *

Also Published As

Publication number Publication date
JP2002512692A (en) 2002-04-23
WO1998054575A2 (en) 1998-12-03
AU7543098A (en) 1998-12-30
EP0986760A2 (en) 2000-03-22
CA2289690A1 (en) 1998-12-03

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