WO1998052478A1 - Systeme de refroidissement pour dispositif a ultrasons - Google Patents

Systeme de refroidissement pour dispositif a ultrasons Download PDF

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Publication number
WO1998052478A1
WO1998052478A1 PCT/US1998/010089 US9810089W WO9852478A1 WO 1998052478 A1 WO1998052478 A1 WO 1998052478A1 US 9810089 W US9810089 W US 9810089W WO 9852478 A1 WO9852478 A1 WO 9852478A1
Authority
WO
WIPO (PCT)
Prior art keywords
lead screw
pusher block
plunger
syringe
fluid
Prior art date
Application number
PCT/US1998/010089
Other languages
English (en)
Inventor
Warren Taylor
Jack Manhard
David Foshee
Original Assignee
Angiosonics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/858,247 external-priority patent/US5971949A/en
Application filed by Angiosonics, Inc. filed Critical Angiosonics, Inc.
Priority to AU75759/98A priority Critical patent/AU7575998A/en
Priority to CA002290530A priority patent/CA2290530A1/fr
Priority to JP55047998A priority patent/JP2002515812A/ja
Priority to EP98923469A priority patent/EP0981298A4/fr
Priority to IL13287898A priority patent/IL132878A0/xx
Publication of WO1998052478A1 publication Critical patent/WO1998052478A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B17/22004—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves
    • A61B17/22012—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for using mechanical vibrations, e.g. ultrasonic shock waves in direct contact with, or very close to, the obstruction or concrement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
    • A61B2017/320069—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic for ablating tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
    • A61B2017/320072—Working tips with special features, e.g. extending parts
    • A61B2017/320073—Working tips with special features, e.g. extending parts probe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
    • A61B2017/320084—Irrigation sleeves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/32—Surgical cutting instruments
    • A61B17/320068—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic
    • A61B2017/320089—Surgical cutting instruments using mechanical vibrations, e.g. ultrasonic node location
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39—Markers, e.g. radio-opaque or breast lesions markers

Definitions

  • the invention relates generally to a cooling system for an ultrasound
  • a cooling system that includes a pump for delivering
  • elongated ultrasound-transmitting probe that includes an ultrasound energy source, a
  • remote locations within a patient must be sized to allow for easy maneuverability and
  • regions of blood vessels, in particular the coronary arteries, are provided.
  • ultrasound treatment system includes an energy source and an ultrasound probe that
  • transmission member such as transmission wire, rod or both
  • the transmission member having a proximal and distal end.
  • the transmission member can be covered in
  • the energy is transmitted to the distal end, which can include a tip, which in
  • a guide catheter can be displaced in a longitudinal direction at the treatment site.
  • the probe may also be provided such that the probe may be slidably disposed within the guide
  • the transmission member can be partially contained within the sheathing that
  • the guiding catheter can be connected to the outlet of a syringe by a conduit
  • syringe pump so that fluid may be provided from the syringe by a syringe pump.
  • a drive mechanism including a motor, gearing and a lead screw, and a pusher block that rides on the lead screw for pushing the plunger of a
  • the drive mechanism can drive the pusher block, which pushes the plunger of
  • the syringe which, in turn, provides fluid via the syringe outlet to the probe.
  • the ultrasound treatment system may include a cooling system for
  • the control system may include: a way to
  • Another object of the invention is to provide an improved method for
  • Yet another object of the invention is to provide an improved pump for
  • the invention accordingly comprises the several steps and the relation of
  • FIG. 1 is a perspective view of an ultrasound transmission system
  • FIG. 2 is a perspective view of a cooling system constructed in
  • FIG. 3 is a perspective view of a syringe pump type assembly
  • FIG. 4 is a plan view of a drive mechanism of a syringe pump assembly
  • FIG. 5 is a side view of an ultrasound transmission device constructed in
  • FIG. 6 is an enlarged side view of a portion of the distal end of a
  • FIG. 7 is a cross-sectional view of a locking mechanism, engaged with a
  • FIG. 8 is a side view of a locking mechanism constructed in accordance
  • FIG. 9 is a side view of the locking mechanism depicted in FIG. 8;
  • FIG. 10 is a cross-sectional view taken along line 10-10, of the locking
  • FIG. 11 is a cross-sectional view taken along line 11-11, of the locking
  • FIG. 9 constructed in accordance with an embodiment of the invention.
  • FIGS. 12A and 12B are cross-sectional views of a locking mechanism in
  • FIGS. 13A and 13B are cross-sectional views of a locking mechanism in
  • FIGS. 14A and 14B are cross-sectional views of a locking mechanism in
  • FIGS. 15A and 15B are cross-sectional views of a locking mechanism in
  • FIGS. 16A and 16B are cross-sectional views of a locking mechanism in
  • FIG. 17 is a side view of a prior art transducer cable connector
  • FIG. 18 is a side view of a transducer cable connector constructed in
  • FIGS. 19A and 19B are cross-sectional views of a prior art half nut
  • FIG. 20 is a schematic of a electronic control system constructed in
  • occlusions and the like is to use an ultrasound probe to deliver ultrasound energy to a
  • an ultrasound probe is provided.
  • probe 200 illustrated generally as probe 200 in FIGS. 1, 5 and 6, and in a copending application
  • Probe 200 is formed with a tapered horn 225, which includes a proximal
  • proximal end 229 is preferably located at a displacement maximum relative to a standing ultrasound wave supported by the overall device. From proximal end 229,
  • horn 225 tapers, in section A thereof, to a reduced diameter distal end 230, of diameter
  • Proximal end 229 must be large enough to receive sufficient energy to
  • in diameter is preferably accomplished in such a manner as to amplify the ultrasound
  • Section C of probe 200 extends distally from transition zone B, and
  • ultrasound device 200 operates in the
  • resonant frequency mode i.e., it supports a standing wave when energized by
  • ultrasound stimulation at proximal end 229, mass 250 is preferably located at a
  • Section C may include multiple subsections having one or multiple
  • section C may include a single transmission wire 240 that
  • Transition zone D may include a
  • transition zone D to support maximum stress, and, as such, transition zone D should be located at or near a displacement maximum (stress minimum).
  • transition zone D may be located at a displacement node or anti-node or at
  • a coolant such as water, saline or another fluid that
  • the coolant can be introduced into a blood vessel.
  • the coolant can be directed over and around
  • the probe for example, by incorporating a sheath 245 (FIG. 6) around some or all
  • Sheathing 245 may be affixed to the probe at one or more of the
  • nodes of section A which are proximal transition section B.
  • proximal transition section B One example of such an
  • FIG. 1 Additional sheathing may be incorporated for
  • Sheathing 245 is advantageously
  • ultrasound device 200 are equally applicable to systems that promote or focus
  • tissue hypothermia for cancer radiation therapy, for example.
  • drugs for example.
  • coolant fluid for cooling the ultrasound probe or delivered through a separate
  • Horn 225 having a tapered section
  • ultrasound energy is provided by a
  • controller 815 Energy is supplied by a power source 246 via a coaxial cable 247 to a
  • Transducer 249 is intimately connected to horn 225.
  • Probe 200 also includes
  • transmission member 240 coupled to horn 225 at the distal end of transition zone B
  • tip 250 coupled to the distal end of transmission member 240.
  • Tip 250 is coupled to three fine wires 260 by use of three openings in the
  • Tip 250 may also be provided with an opening for a guidewire, and a guidewire tube may be installed in the opening and
  • Fine wires 260 may be
  • a gap 260' is advantageously provided between the
  • Wire 240 may also be sheathed and that sheathing may be connected to the
  • One known way of delivering a coolant to ultrasound probe 200 is to use
  • a syringe pump-type device such as those typically used to infuse medication into a
  • a syringe pump-type device generally includes a motor, a pusher
  • the pusher block generally includes a half nut
  • plunger which pushes fluid into an infusion line.
  • a pusher block 334 includes a housing 390, which houses a half
  • Half nut 305 is located below and substantially perpendicular
  • Pusher block 334 also includes a push button 360, which is
  • button 360 includes a shaft 361 and a cap 362.
  • Pusher block 334 may be positioned along lead screw 310 by depressing
  • half nut 305 moves along the thread of lead screw 310 until pusher block 334
  • pusher block 334 becomes greater than the countering force of the syringe, pusher block 334 begins
  • lead screw 310 When lead screw 310 begins turning, it exerts a normal force
  • half nut "floats" so that the normal force may be reduced by shifting sideways, thereby
  • slippage of the half nut on the lead screw can occur.
  • One way to prevent slippage is to increase the spring force constant k of compression spring 320.
  • spring force constant k of compression spring 320 is to increase the spring force constant k of compression spring 320.
  • the spring made it more difficult for the user to manually position the pusher block.
  • a cooling system generally indicated at 500,
  • Cooling system 500 includes a housing 32, a controller 815, a syringe pump 30 for
  • cooling system 500 When probe 200 is activated, cooling system 500 provides coolant to
  • the transmission wire sections of probe 200 can quickly heat to a level
  • housing 32 includes a display panel 79, a
  • back panel 140 a back casing 141, a front casing 142, all of which can be formed of
  • top casing 83 which is hinged to back panel 140 by
  • Top casing 83 may be rotated about casing hinge 78 to expose
  • Display panel 79 contains the operator control panel (not shown).
  • Back panel 140 includes foot pedal plug 145 for receiving a foot pedal cable (not
  • syringe pump 30 is contained within housing
  • housing 32 includes a support 90 disposed within and supported by housing 32. As is,
  • support 90 includes a top platform 91, a bottom platform 92,
  • bottom platform 92 and top platform 91 bottom platform 92 and top platform 91.
  • syringe 50 of pump 30 includes a
  • barrel 52 having a distal end 204 with an outlet 55, and a proximal end 205, having a
  • Syringe 50 also includes a plunger 54, having a proximal end 207, which
  • proximal flange 56 has a proximal flange 56, and a distal end 206, which has a distal flange 206, sized to
  • top platform 91 is divided into an upper portion 47 and a lower portion 48, which
  • syringe 50 are joined by a hinge 49, and are releasably connected by a lockdown mechanism 51.
  • Upper portion 47 can be pivoted about hinge 49 to permit barrel 52 of syringe 50 to be
  • Syringe 50 is positioned in cradle 46 such that an upper
  • flange 53 is not disposed within cradle 46. Rather an underside 53a of flange 53
  • a drive mechanism 36 which includes a motor 40 having a shaft 41, coupled
  • Pusher block 34 is guided by a first rail 80 and a second rail 81.
  • First rail 80 First rail 80
  • first upright 76 and second upright 77 are mounted at each end to first upright 76 and second upright 77.
  • the speed of lead screw 44 is monitored by an encoder 39, mounted on upright 76,
  • Lead screw 44 is axially supported by bearings (not shown), which in
  • Reducer 42 which operatively couples lead screw 44 to motor 40 may include appropriately sized gears to reduce the speed of motor shaft 41 to an
  • reducer 42 includes
  • pusher block 34 includes a housing 66
  • Wing 68 includes a T-bar 73 and a pusher block
  • T-bar 73 is advantageously formed of plastic material which
  • Housing 66 is
  • housing 66 is generally cylindrical in shape at its upper one-third,
  • top platform 91 to form a rectangular block shaped base 85.
  • Housing 66 is bored to
  • plug bore 87 which accommodates pusher block biasing assembly 62.
  • biasing assembly 62 is held within housing 66 by lower plug 119.
  • the upper third of housing 66 has two opposing slots 67 that permit T-bar 73 to be
  • Wing 68 is supported on T-bar 73, which in turn is supported on slots 67
  • housing 66 includes a first arm 71 on one side, a second arm 72 on the other
  • First arm 71 is integrally connected with second
  • Wing catch 74 includes a lower surface 74a and a notch
  • Wing 68 may be formed of metal or a composite material, but preferably is
  • Base 85 of housing 66 has a first bore 86 at one side thereof, a second
  • housing 66 an in the same plane to provide stability to pusher block 34.
  • bores
  • 86, 88 and 89 are preferably spaced apart from one another along the same plane.
  • bushings 86a and 88a disposed within bores 86 and 88 are bushings 86a and 88a,
  • Bore 86 is further preferably formed of Teflon®, to minimize wear to base 85. Bore 86 is further
  • tubing 86b preferably formed of bronze, to provide stability to pusher
  • First bore 86 and second bore 88 are
  • bushing 86a tubing 86b and first rail 80, and bushing
  • Central bore 89 is sized to accommodate lead
  • First rail 80 and second rail 81 are provided to ensure that pusher block 34
  • pusher block 34 is made to
  • housing 66 provides the
  • Housing 66 also includes an antisiphon catch 65
  • a pressure plate 35 which are integrally connected, preferably formed of a plastic
  • Antisiphon catch 65 is V-shaped and is connected to
  • Antisiphon catch 65 has a notch 64
  • Wingcatch notch 74b is similarly configured to
  • Pressure plate 35 is mounted on housing 66 so that when flange 56 is
  • a force sensor 70 advantageously
  • force sensor 70 includes a sensor button 70a, which is mounted on
  • Force sensor 70 feeds an output signal to controller 815, which
  • wing 68 is formed to overlap T-bar 73
  • T-bar 73 includes a top portion 132, which is attached at its outer edges to wing 68 at
  • first arm 71 and second arm 72 and a stem 133, which extends through slots 67 into
  • T-bar 73 is preferably bolted to arms 71
  • An upper plug 119 is formed in the shape of a cylinder, sized to fit within
  • Upper plug 119 is preferably machined from bronze, and functions
  • pusher block 34 includes push button 60, a plunger 110, having a plunger upper end
  • Plunger 110 preferably is formed of bronze. Upper end 113 is connected to push
  • Push button 60 is bored to accept an upper end of plunger spring 112.
  • Push button 60 is preferably formed of aluminum, and has a shaft 63, which is bored to permit the
  • plunger spring 112 occupies the space defined
  • plunger actuator 114 within housing 66.
  • FIGS. 10 and 11 In a preferred embodiment of the invention, shown in FIGS. 10 and 11,
  • plunger 110 has a bore 125, having an upper edge 126 and a lower edge 127, and an
  • bore 125 is threaded so that it can engage lead screw 44.
  • compression spring 115 biases lower edge 127 against
  • lead screw 44 be positioned along the length of lead screw 44.
  • antisiphon catch 65 the user permits pusher block 34 to engage lead screw 44.
  • FIGS. 1-10 An embodiment of the invention, shown at FIGS.
  • 16A and 16B was designed employing some of the components of the conventional
  • Locking mechanism 150 is preferably made of aluminum, and formed
  • a pawl 103 having a tongue 101, an actuating portion 102, and a pawl spring
  • Half nut 120 is threaded to mesh with lead screw 44, and notched at a notch 122
  • Pawl spring 118 is connected to housing 66 so as to hinge pawl
  • FIG. 16A which depicts locking mechanism 150
  • locking mechanism 150 in an engaged position, locking mechanism 150 is spring-biased such that tongue 101
  • Pusher block 34 is designed to
  • Wing 68 is permitted to
  • half nut 120 contacts
  • plunger 1 10 is forced downward in a direction
  • actuator 114 of plunger 110 contacts
  • plunger 110 is permitted to contact half nut 120 and transmit the force
  • antisiphon catch 65 the user pulls up on wing 68 in a direction shown as arrow X in
  • FIG. 16B In this way, wing 68 travels upwardly in slots 67 acting against plunger
  • the distance W is large enough to accommodate spring flange 56.
  • plunger flange 56 is positioned within antisiphon catch 65.
  • locking mechanism 150 can only be released if the user simultaneously presses down
  • FIGS. 10 and 11 In a second embodiment of the invention, depicted at FIGS. 10 and 11,
  • 16A and 16B is integral with plunger 110, and plunger 110 is maintained in its first
  • This embodiment permits locking mechanism
  • locking mechanism 100 includes a ball bearing 108, which is
  • plunger 110 positioned within a channel 107 in housing 66 and a recess 109 in plunger 110.
  • FIGS. 12A and 12B Pusher block 34 is in a first position where locking mechanism
  • plunger 110 is able to move in the downward direction because ball bearing 108 no
  • plunger 110 acts against and overcomes compression spring
  • diameter of channel 107 is slightly greater than the diameter of ball bearing 108 and
  • the outer diameter of channel 107 is slightly less than the diameter of ball bearing 108.
  • FIGS. 14A and 14B another embodiment of a locking mechanism
  • FIG. 14A depicts locking mechanism
  • 14B depicts locking mechanism 450 in its unlocked position, where plunger 110 is
  • Locking mechanism 450 includes a triangle-
  • Bar 151 can be located anywhere along the length of plunger 110.
  • Plunger 110 includes notch 152, which is
  • Hinge 153 is connected to housing 66 and to one end of bar 151,
  • middle portion 73 prevents
  • this embodiment provides a novel structure that serves to lock pressure
  • a locking mechanism 550 constructed
  • FIG. 15A depicts
  • FIG. 15B shows locking mechanism
  • Locking mechanism 550 in an unlocked position.
  • Locking mechanism 550 includes a latch 161, a notch
  • Locking mechanism 550 is similar to locking
  • hinge 163 biases latch 151 in a direction shown by an arrow S. Latch 161 is prevented
  • portion 73 no longer retains latch 161. As such, latch 161 rotates away from plunger
  • FIGS. 13A and 13B show a locking mechanism 650, constructed in
  • FIG. 13 A depicts locking
  • FIG. 13B shows locking mechanism 650 in a locked position
  • Locking mechanism 650 includes a plurality of ball bearings
  • an upper plug 619 formed with a wide diameter portion 620, a narrowed portion
  • Upper plug 619 is preferably formed of bronze, and is sized to
  • This embodiment differs from the other embodiments, as locking
  • mechanism 650 is entirely contained within housing 66. That is, ball bearings 644 are
  • FIG. 20 shows a schematic diagram of
  • an electronic control system for controlling cooling system
  • Electronic control system 800 monitors the functioning of
  • control board 810 which is in turn
  • controller 815 As is shown in FIG. 20, a pulse generator 870 is controlled
  • Controller 815 instructs pulse generator
  • pulses are sent to an output buffer 880 by a signal 871.
  • Output buffer 880 receives signal 871 from pulse generator 870 and forwards this
  • motor driver 890 drives motor 40 in a conventional manner
  • controller 815 In addition to generating outputs for driving motor 40, controller 815,
  • control board 810 collects inputs from three distinct sensor areas.
  • drive mechanism 36 is depicted having
  • Encoder 39 operatively coupled to the distal end of lead screw 44. Encoder 39 senses
  • Counter 817 determines the relative movement that should
  • signal 801 are forwarded to controller 815 as signal 802, which compares these two
  • lead screw 44 is not moving as it should be, and that drive mechanism 36 could be
  • controller 815 will shut down probe
  • probe 200 may be operated without coolant fluid
  • the controller can be
  • the second sensor area includes force sensor 70 (noted above) which
  • the controller may detect when syringe 50, conduit 98, or
  • cooling system 500 monitors situations where the force or pressure is less than the lower force or pressure limit and situations where force or pressure is greater
  • converter 830 receives this amplified analog
  • the range of pressure may be defined based on the force detected by
  • a user may identify the syringe size by inputting the syringe size into the user interface 148 on display panel 79 (FIG. 1). For a given
  • the cross-sectional area of the barrel is known, and therefore knowing the
  • probe 200 may be operated without coolant fluid delivery for a time
  • the controller may sound an alarm
  • the third sensor area includes sensors which are
  • a first sensor 840 detects when
  • a signal 806 is sent to an input buffer 860, which sends a signal 807 to
  • controller 815 through control board 810 to warn controller 815 that the fluid level is
  • pulse generator 870 is
  • Signal 808 is also sent to controller 815 through control board 810 to
  • Input buffer 860 comprises appropriate logic
  • first and second signals 806 and 808 are properly sent to control board 810.
  • controller 815 instructs
  • Systems in accordance with the invention include a way to adjust the
  • force sensor 70 may be fed to the controller so that the motor input signal may be
  • coolant system 500 For example, in a preferred embodiment of the invention, syringe
  • 50 is capable of delivering 60 ml of fluid.
  • probe 200 requires 20 to 30 ml of fluid during the time the probe is activated.
  • coolant delivery is enabled by controller 815 only during
  • controller 815 signals motor 40 to drive syringe
  • syringe plunger 54 is driven at about 33 psi
  • motor 40 is energized to drive syringe
  • fluid is provided at 1 ml/minute when probe 200 is in an idling mode.
  • probe 200 is prevented from introducing air into a patient's vasculature when probe 200 is introduced into a patient's body and prevents blood from
  • transducer connector 600 is depicted as connecting cable 602 to transducer 601.
  • a connector in the prior art was an integral part of transducer 601. That is, cable 602
  • transducer 601 was hard-wired to transducer 601. Because transducer 601 is screwed onto the
  • Disconnect 700 is shown as releasable from transducer 701. In this manner, any twist

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un système de traitement par ultrasons, ainsi qu'un procédé d'utilisation d'ultrasons pour traiter les régions sténosées et obstruées de vaisseaux sanguins. Ce système comprend: une source d'énergie (815), une sonde ultrasonore (200), permettant d'appliquer de l'énergie ultrasonore sur le site du traitement, cette sonde étant pourvue d'au moins un élément de transmission (A), un passage (245) communiquant avec ledit élément de transmission de la sonde (200), un système d'alimentation de fluide comprenant un mécanisme d'entraînement (36), une bloc-poussoir (34) destiné à être entraîné par ce mécanisme d'entraînement, une seringue (50) qui alimente ledit passage (245) en fluide afin de refroidir la sonde ultrasonore (200), et un mécanisme de verrouillage (150) conçu pour empêcher ledit bloc-poussoir (34) de se détacher du mécanisme d'entraînement en cours de fonctionnement.
PCT/US1998/010089 1997-05-19 1998-05-15 Systeme de refroidissement pour dispositif a ultrasons WO1998052478A1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU75759/98A AU7575998A (en) 1997-05-19 1998-05-15 Cooling system for ultrasound device
CA002290530A CA2290530A1 (fr) 1997-05-19 1998-05-15 Systeme de refroidissement pour dispositif a ultrasons
JP55047998A JP2002515812A (ja) 1997-05-19 1998-05-15 超音波装置用冷却システム
EP98923469A EP0981298A4 (fr) 1997-05-19 1998-05-15 Systeme de refroidissement pour dispositif a ultrasons
IL13287898A IL132878A0 (en) 1997-05-19 1998-05-15 Cooling system for ultrasound device

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4702297P 1997-05-19 1997-05-19
US60/047,022 1997-05-19
US08/858,247 1997-05-19
US08/858,247 US5971949A (en) 1996-08-19 1997-05-19 Ultrasound transmission apparatus and method of using same

Publications (1)

Publication Number Publication Date
WO1998052478A1 true WO1998052478A1 (fr) 1998-11-26

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/010089 WO1998052478A1 (fr) 1997-05-19 1998-05-15 Systeme de refroidissement pour dispositif a ultrasons

Country Status (7)

Country Link
EP (1) EP0981298A4 (fr)
JP (1) JP2002515812A (fr)
AU (1) AU7575998A (fr)
CA (1) CA2290530A1 (fr)
IL (1) IL132878A0 (fr)
TW (1) TW384227B (fr)
WO (1) WO1998052478A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2493570A1 (fr) * 2009-10-26 2012-09-05 Vytronus, Inc. Méthodes et systèmes utilisés en vue d'une ablation tissulaire
US8475375B2 (en) 2006-12-15 2013-07-02 General Electric Company System and method for actively cooling an ultrasound probe
CN102078664B (zh) * 2009-11-27 2015-04-22 重庆融海超声医学工程研究中心有限公司 绑带式超声波治疗装置
US20200215265A1 (en) * 2016-06-17 2020-07-09 Becton, Dickinson And Company Method and Apparatus for Wetting Internal Fluid Path Surfaces of a Fluid Port to Increase Ultrasonic Signal Transmission

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4598706B2 (ja) * 2006-03-29 2010-12-15 テルモ株式会社 血液初流採取装置
TWI733344B (zh) * 2020-02-21 2021-07-11 國立臺灣大學 超音波裝置

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US47022A (en) 1865-03-28 Improvement in hand mowing-machines
US3631847A (en) * 1966-03-04 1972-01-04 James C Hobbs Method and apparatus for injecting fluid into the vascular system
US3812843A (en) * 1973-03-12 1974-05-28 Lear Siegler Inc Method and apparatus for injecting contrast media into the vascular system
US4870953A (en) 1987-11-13 1989-10-03 Donmicheal T Anthony Intravascular ultrasonic catheter/probe and method for treating intravascular blockage
US4952205A (en) * 1987-04-04 1990-08-28 B. Braun Melsungen Ag Pressure infusion device
US5269297A (en) 1992-02-27 1993-12-14 Angiosonics Inc. Ultrasonic transmission apparatus

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4424720A (en) * 1980-12-15 1984-01-10 Ivac Corporation Mechanism for screw drive and syringe plunger engagement/disengagement
GR1000159B (el) * 1989-06-15 1991-10-10 Micrel Kentro Efarm Mikroilekt Αντλια συριγγας.
US5403324A (en) * 1994-01-14 1995-04-04 Microsonic Engineering Devices Company, Inc. Flexible catheter with stone basket and ultrasonic conductor

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US47022A (en) 1865-03-28 Improvement in hand mowing-machines
US3631847A (en) * 1966-03-04 1972-01-04 James C Hobbs Method and apparatus for injecting fluid into the vascular system
US3812843A (en) * 1973-03-12 1974-05-28 Lear Siegler Inc Method and apparatus for injecting contrast media into the vascular system
US4952205A (en) * 1987-04-04 1990-08-28 B. Braun Melsungen Ag Pressure infusion device
US4870953A (en) 1987-11-13 1989-10-03 Donmicheal T Anthony Intravascular ultrasonic catheter/probe and method for treating intravascular blockage
US5269297A (en) 1992-02-27 1993-12-14 Angiosonics Inc. Ultrasonic transmission apparatus

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP0981298A4

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8475375B2 (en) 2006-12-15 2013-07-02 General Electric Company System and method for actively cooling an ultrasound probe
EP2493570A1 (fr) * 2009-10-26 2012-09-05 Vytronus, Inc. Méthodes et systèmes utilisés en vue d'une ablation tissulaire
CN102078664B (zh) * 2009-11-27 2015-04-22 重庆融海超声医学工程研究中心有限公司 绑带式超声波治疗装置
US20200215265A1 (en) * 2016-06-17 2020-07-09 Becton, Dickinson And Company Method and Apparatus for Wetting Internal Fluid Path Surfaces of a Fluid Port to Increase Ultrasonic Signal Transmission

Also Published As

Publication number Publication date
AU7575998A (en) 1998-12-11
TW384227B (en) 2000-03-11
EP0981298A1 (fr) 2000-03-01
IL132878A0 (en) 2001-03-19
JP2002515812A (ja) 2002-05-28
EP0981298A4 (fr) 2000-12-06
CA2290530A1 (fr) 1998-11-26

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