WO1998052461A1 - Procede d'imagerie cardiaque par irm mettant en oeuvre une bobine receptrice interne et une bobine receptrice externe - Google Patents

Procede d'imagerie cardiaque par irm mettant en oeuvre une bobine receptrice interne et une bobine receptrice externe Download PDF

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Publication number
WO1998052461A1
WO1998052461A1 PCT/US1998/010595 US9810595W WO9852461A1 WO 1998052461 A1 WO1998052461 A1 WO 1998052461A1 US 9810595 W US9810595 W US 9810595W WO 9852461 A1 WO9852461 A1 WO 9852461A1
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WO
WIPO (PCT)
Prior art keywords
heart
magnetic resonance
coil
image
signal
Prior art date
Application number
PCT/US1998/010595
Other languages
English (en)
Inventor
Lawrence A. Minkoff
Valentin Fuster
Original Assignee
Cardiac M.R.I., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiac M.R.I., Inc. filed Critical Cardiac M.R.I., Inc.
Priority to AU75947/98A priority Critical patent/AU7594798A/en
Publication of WO1998052461A1 publication Critical patent/WO1998052461A1/fr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/055Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves  involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
    • A61B5/004Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0044Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the heart

Definitions

  • the present invention relates to a magnetic resonance imaging (MRI) probe. More specifically, the present invention relates to an apparatus and method for passing an MRI probe (which includes a receiving coil) through either the mouth or the nose, into the esophagus to be positioned adjacent to the heart and/or aorta.
  • This MRI probe may be used with an external MRI receiving coil placed on the patient's chest to provide one combined image of this area of the body from both coils.
  • X-ray angiography and angioplasty only provide a physician with information regarding blood flow, and the amount of an occlusion in the vessel. Moreover, the reasons for an occlusion may not be apparent because no information regarding the underlying biochemistry of the occlusion is provided by these conventional techniques.
  • Magnetic resonance imaging is based on the chemistry of the observed tissue. Therefore, MRI provides not only more detailed information of the structures being imaged, but also provides information on the chemistry of the imaged structures.
  • the plaque that causes the blockage in the brain that results in a stroke frequently originates in the aorta. But there are different types of plaque.
  • One type of plaque is very stable and is not likely to cause problems.
  • another type of plaque is unstable and can break off from inside the aorta, thereby increasing the risk of stroke.
  • These different types of plaque that are contained within the aorta can be identified by MRI as has been described, for example, by J.F. Toussaint et al. , Circulation, Vol. 94, pp.
  • MR imaging of the heart has been achieved with the use of a body coil (i.e., a receiving coil that completely surrounds the torso).
  • a body coil i.e., a receiving coil that completely surrounds the torso.
  • an external body coil provides a relatively low signal to noise (SNR) when the object to be imaged is the heart
  • MRI has also become a useful tool to monitor an effective drug therapy. Because MRI does not have the dangerous side effects that are associated with X-rays, it is possible to monitor patients throughout their treatment and adjust their drug regimen as necessary.
  • MRI is used to pick up a signal of a small object from a relatively large receiving coil.
  • Fig. 1 is a cross-sectional view of the MR probe in accordance with the present invention.
  • Fig. 2 is a partial rear view, with parts broken away of the heart, showing the pericardium and esophagus; and Fig. 3 is a cross-sectional view of the chest of a human body, showing the heart's pericardial sac, aorta and esophagus.
  • Probe 10 includes a tube 12 that has a first proximal end 14 and a second distal end 16.
  • the distal end 16 of tube 12 is preferably made of a relatively soft material (e.g. , plastic).
  • Distal end 16 is inserted into a balloon assembly 18.
  • Balloon assembly 18 is comprised of an inner balloon 20 and an outer balloon 22.
  • Inner balloon 20 defines an internal chamber 28 that receives the distal end 16 of tube 12.
  • a receiving coil 24 is mounted between the inner balloon 20 and the outer balloon 22. Receiving coils are necessary in MRI apparati to produce an image.
  • Coil 24 may be a known type of device, see, for example, U.S. Patent No. 4,791,372 to Kirk et al.
  • Tube 12 includes a fluid conduit 26 that communicates with internal chamber 28. Conduit 26 can be fluidly connected at proximal end 14 to a source of fluid pressure to selectively inflate and deflate the inner balloon as desired. Tube 12 also includes an electronic communication line 30 that electronically connects to receiving coil 24 at distal end 16. Communication line 30 can be electronically connected to a conventional MRI apparatus at proximal end 14 to produce an image based on the signal produced by coil 24.
  • the MRI apparatus can be, for example, a GE Signa, 1.5 Tesla, which is commercially available from General Electric Company.
  • An external MRI receiving coil 32 is electronically connected to an electronic communication line 34.
  • External MRI receiving coil 32 may be a known type of device, such as, for example, a quadrature or phased-array coil.
  • the currently preferred external coil is the type described by Fayad et al. , An Improved Quadrature Array Coil for MR Cardiac Imaging, JMRI, Volume 2, Number 2, pp. 229-232 (1992), the disclosure of which is hereby incorporated by reference.
  • Communication line 34 can be electronically connected to a conventional MRI apparatus to produce an image base on the signal produced by coil 32.
  • the signals produced by the internal coil 24 and the external coil 32 can each be used to produce an image of the heart and/or the vessels emanating from the heart. These images or signals can be combined by a conventional MRI apparatus to produce a combined image, as one skilled in the art would readily recognize. This combined image has a superior signal to noise ratio and provides a larger coverage area than the image provided from either individual coil.
  • the balloon assembly 18 is deflated and the outer surface of outer balloon 22 is preferably well lubricated with a conventional, sterile, water- soluble lubricant.
  • the distal end 16 of probe 10 is then inserted either into the mouth or the nose.
  • the size of the probe should be reduced (e.g. , V7 diameter) accordingly.
  • Distal end 16, which is surrounded by balloon assembly 18, then passes into the esophagus.
  • Tube 12 is continuously inserted into the mouth or nose until the receiving coil 24 is placed in the desired position within the esophagus, as close to the object to be imaged as possible.
  • the receiver coil 24 should be placed within the esophagus behind and under the heart and the aortic arch (See Figs. 2 and 3).
  • the balloon assembly 18 is inflated to maintain the position of receive coil 24 within the esophagus and so that the receiver coil will be at as large a diameter as possible without causing harm to the esophagus.
  • the amount that the balloon is inflated will vary from patient to patient, but will typically be on the order of about one-half inch in diameter by five inches in length when inflated.
  • the use of receiving coil 24 alone may be sufficient to obtain an adequate image of the aortic arch.
  • the SNR of coil 24 was 30: 1 at a radius of six (6) cm and was 15: 1 at a radius of seven (7) cm.
  • the prior art whole body coil has a
  • the internal coil 24 will produce better SNRs when the object is within, for example, a 7 cm radius.
  • the internal coil 24 will produce a better image of the aortic arch, and the rear portion of the heart (i.e. , of objects that are relatively close to it) while the external coil 32 will produce a better image of the front portion of the heart because it is disposed closer to the front portion of the heart.
  • the signals from the internal coil 24 and the external coil 32 will produce a good quality combined image of the entire heart having a SNR > 20, and preferably a SNR > 30.
  • the second conventional coil 32 can be disposed on the chest to enhance the images received by coil 24.
  • the MRI apparatus can produce an image from the signal received from coil 24 and a second image from the signal received from coil 32.
  • the MRI apparatus can then combine the images of chest coil 32 and coil 24, which is placed within the esophagus, to produce a more even illuminated combined image of the front and rear portions of the heart and/or its surrounding veins and arteries.
  • the MRI apparatus can produce a combined image from the signals received from coils 24, 32.
  • the combined image has significantly higher SNR than images produced from prior art external receiving coils, including a body coil.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Cardiology (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

Cette invention concerne un procédé d'imagerie cardiaque qui permet d'obtenir des images du coeur ou des vaisseaux partant du coeur à l'aide de première et deuxième bobines réceptrices (24, 32) de résonance magnétique. On obtient l'image en faisant passer la première bobine de résonance magnétique dans l'oesophage. On place cette première bobine dans l'oesophage juste à côté du coeur et de l'arc aortique et il génère un premier signal qui produit une première image du coeur ou des vaisseaux partant du coeur. On place la deuxième bobine de résonance magnétique sur le torse à proximité du coeur, cette deuxième bobine générant un deuxième signal qui produit une deuxième image du coeur ou des vaisseaux partant du coeur. La combinaison des première et deuxième images produit une image combinée du coeur ou des vaisseaux partant du coeur.
PCT/US1998/010595 1997-05-21 1998-05-20 Procede d'imagerie cardiaque par irm mettant en oeuvre une bobine receptrice interne et une bobine receptrice externe WO1998052461A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU75947/98A AU7594798A (en) 1997-05-21 1998-05-20 Cardiac mri with an internal receiving coil and an external receiving coil

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4726397P 1997-05-21 1997-05-21
US60/047,263 1997-05-21

Publications (1)

Publication Number Publication Date
WO1998052461A1 true WO1998052461A1 (fr) 1998-11-26

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PCT/US1998/010595 WO1998052461A1 (fr) 1997-05-21 1998-05-20 Procede d'imagerie cardiaque par irm mettant en oeuvre une bobine receptrice interne et une bobine receptrice externe

Country Status (2)

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AU (1) AU7594798A (fr)
WO (1) WO1998052461A1 (fr)

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6263229B1 (en) 1998-11-13 2001-07-17 Johns Hopkins University School Of Medicine Miniature magnetic resonance catheter coils and related methods
EP1293793A1 (fr) * 2001-09-18 2003-03-19 Jomed Nv Cathéter pour l'IRM
WO2003051192A2 (fr) * 2001-12-14 2003-06-26 Scimed Life Systems, Inc. Recanalisation de vaisseaux occlus guidee par resonance magnetique
US6606513B2 (en) 2000-02-01 2003-08-12 Surgi-Vision, Inc. Magnetic resonance imaging transseptal needle antenna
US6701176B1 (en) 1998-11-04 2004-03-02 Johns Hopkins University School Of Medicine Magnetic-resonance-guided imaging, electrophysiology, and ablation
USRE42856E1 (en) 2002-05-29 2011-10-18 MRI Interventions, Inc. Magnetic resonance probes
US8095224B2 (en) 2009-03-19 2012-01-10 Greatbatch Ltd. EMI shielded conduit assembly for an active implantable medical device
US8509913B2 (en) 2001-04-13 2013-08-13 Greatbatch Ltd. Switched diverter circuits for minimizing heating of an implanted lead and/or providing EMI protection in a high power electromagnetic field environment
US8855785B1 (en) 2001-04-13 2014-10-07 Greatbatch Ltd. Circuits for minimizing heating of an implanted lead and/or providing EMI protection in a high power electromagnetic field environment
US8882763B2 (en) 2010-01-12 2014-11-11 Greatbatch Ltd. Patient attached bonding strap for energy dissipation from a probe or a catheter during magnetic resonance imaging
US8886288B2 (en) 2009-06-16 2014-11-11 MRI Interventions, Inc. MRI-guided devices and MRI-guided interventional systems that can track and generate dynamic visualizations of the devices in near real time
US8903505B2 (en) 2006-06-08 2014-12-02 Greatbatch Ltd. Implantable lead bandstop filter employing an inductive coil with parasitic capacitance to enhance MRI compatibility of active medical devices
US8989870B2 (en) 2001-04-13 2015-03-24 Greatbatch Ltd. Tuned energy balanced system for minimizing heating and/or to provide EMI protection of implanted leads in a high power electromagnetic field environment
US9108066B2 (en) 2008-03-20 2015-08-18 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
US9119968B2 (en) 2006-06-08 2015-09-01 Greatbatch Ltd. Band stop filter employing a capacitor and an inductor tank circuit to enhance MRI compatibility of active medical devices
US9242090B2 (en) 2001-04-13 2016-01-26 MRI Interventions Inc. MRI compatible medical leads
US9248283B2 (en) 2001-04-13 2016-02-02 Greatbatch Ltd. Band stop filter comprising an inductive component disposed in a lead wire in series with an electrode
US9259290B2 (en) 2009-06-08 2016-02-16 MRI Interventions, Inc. MRI-guided surgical systems with proximity alerts
US9295828B2 (en) 2001-04-13 2016-03-29 Greatbatch Ltd. Self-resonant inductor wound portion of an implantable lead for enhanced MRI compatibility of active implantable medical devices
US9427596B2 (en) 2013-01-16 2016-08-30 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
USRE46699E1 (en) 2013-01-16 2018-02-06 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
US9931514B2 (en) 2013-06-30 2018-04-03 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
US10080889B2 (en) 2009-03-19 2018-09-25 Greatbatch Ltd. Low inductance and low resistance hermetically sealed filtered feedthrough for an AIMD
US10350421B2 (en) 2013-06-30 2019-07-16 Greatbatch Ltd. Metallurgically bonded gold pocket pad for grounding an EMI filter to a hermetic terminal for an active implantable medical device
US10559409B2 (en) 2017-01-06 2020-02-11 Greatbatch Ltd. Process for manufacturing a leadless feedthrough for an active implantable medical device
US10561837B2 (en) 2011-03-01 2020-02-18 Greatbatch Ltd. Low equivalent series resistance RF filter for an active implantable medical device utilizing a ceramic reinforced metal composite filled via
US10589107B2 (en) 2016-11-08 2020-03-17 Greatbatch Ltd. Circuit board mounted filtered feedthrough assembly having a composite conductive lead for an AIMD
US10905888B2 (en) 2018-03-22 2021-02-02 Greatbatch Ltd. Electrical connection for an AIMD EMI filter utilizing an anisotropic conductive layer
US10912945B2 (en) 2018-03-22 2021-02-09 Greatbatch Ltd. Hermetic terminal for an active implantable medical device having a feedthrough capacitor partially overhanging a ferrule for high effective capacitance area
US11198014B2 (en) 2011-03-01 2021-12-14 Greatbatch Ltd. Hermetically sealed filtered feedthrough assembly having a capacitor with an oxide resistant electrical connection to an active implantable medical device housing

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US3757773A (en) * 1972-03-22 1973-09-11 Univ California External field electromagnetic flow sensor-artery
US5307814A (en) * 1991-09-17 1994-05-03 Medrad, Inc. Externally moveable intracavity probe for MRI imaging and spectroscopy
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US5413104A (en) * 1992-11-10 1995-05-09 Drager Medical Electronics B.V. Invasive MRI transducers
US5447156A (en) * 1994-04-04 1995-09-05 General Electric Company Magnetic resonance (MR) active invasive devices for the generation of selective MR angiograms
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Patent Citations (6)

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US3757773A (en) * 1972-03-22 1973-09-11 Univ California External field electromagnetic flow sensor-artery
US5476095A (en) * 1989-02-24 1995-12-19 Medrad, Inc. Intracavity probe and interface device for MRI imaging and spectroscopy
US5307814A (en) * 1991-09-17 1994-05-03 Medrad, Inc. Externally moveable intracavity probe for MRI imaging and spectroscopy
US5402788A (en) * 1992-06-25 1995-04-04 Olympus Optical Co., Ltd. Diagnostic system using nuclear magnetic resonance phenomenon
US5413104A (en) * 1992-11-10 1995-05-09 Drager Medical Electronics B.V. Invasive MRI transducers
US5447156A (en) * 1994-04-04 1995-09-05 General Electric Company Magnetic resonance (MR) active invasive devices for the generation of selective MR angiograms

Cited By (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6701176B1 (en) 1998-11-04 2004-03-02 Johns Hopkins University School Of Medicine Magnetic-resonance-guided imaging, electrophysiology, and ablation
US9301705B2 (en) 1998-11-04 2016-04-05 Johns Hopkins University School Of Medicine System and method for magnetic-resonance-guided electrophysiologic and ablation procedures
US6263229B1 (en) 1998-11-13 2001-07-17 Johns Hopkins University School Of Medicine Miniature magnetic resonance catheter coils and related methods
US6606513B2 (en) 2000-02-01 2003-08-12 Surgi-Vision, Inc. Magnetic resonance imaging transseptal needle antenna
US9295828B2 (en) 2001-04-13 2016-03-29 Greatbatch Ltd. Self-resonant inductor wound portion of an implantable lead for enhanced MRI compatibility of active implantable medical devices
US8509913B2 (en) 2001-04-13 2013-08-13 Greatbatch Ltd. Switched diverter circuits for minimizing heating of an implanted lead and/or providing EMI protection in a high power electromagnetic field environment
US8989870B2 (en) 2001-04-13 2015-03-24 Greatbatch Ltd. Tuned energy balanced system for minimizing heating and/or to provide EMI protection of implanted leads in a high power electromagnetic field environment
US8855785B1 (en) 2001-04-13 2014-10-07 Greatbatch Ltd. Circuits for minimizing heating of an implanted lead and/or providing EMI protection in a high power electromagnetic field environment
US9248283B2 (en) 2001-04-13 2016-02-02 Greatbatch Ltd. Band stop filter comprising an inductive component disposed in a lead wire in series with an electrode
US9242090B2 (en) 2001-04-13 2016-01-26 MRI Interventions Inc. MRI compatible medical leads
EP1293793A1 (fr) * 2001-09-18 2003-03-19 Jomed Nv Cathéter pour l'IRM
WO2003051192A3 (fr) * 2001-12-14 2003-10-09 Scimed Life Systems Inc Recanalisation de vaisseaux occlus guidee par resonance magnetique
WO2003051192A2 (fr) * 2001-12-14 2003-06-26 Scimed Life Systems, Inc. Recanalisation de vaisseaux occlus guidee par resonance magnetique
USRE44736E1 (en) 2002-05-29 2014-01-28 MRI Interventions, Inc. Magnetic resonance probes
USRE42856E1 (en) 2002-05-29 2011-10-18 MRI Interventions, Inc. Magnetic resonance probes
US9119968B2 (en) 2006-06-08 2015-09-01 Greatbatch Ltd. Band stop filter employing a capacitor and an inductor tank circuit to enhance MRI compatibility of active medical devices
US8903505B2 (en) 2006-06-08 2014-12-02 Greatbatch Ltd. Implantable lead bandstop filter employing an inductive coil with parasitic capacitance to enhance MRI compatibility of active medical devices
US9108066B2 (en) 2008-03-20 2015-08-18 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
US10080889B2 (en) 2009-03-19 2018-09-25 Greatbatch Ltd. Low inductance and low resistance hermetically sealed filtered feedthrough for an AIMD
US8095224B2 (en) 2009-03-19 2012-01-10 Greatbatch Ltd. EMI shielded conduit assembly for an active implantable medical device
US9259290B2 (en) 2009-06-08 2016-02-16 MRI Interventions, Inc. MRI-guided surgical systems with proximity alerts
US9439735B2 (en) 2009-06-08 2016-09-13 MRI Interventions, Inc. MRI-guided interventional systems that can track and generate dynamic visualizations of flexible intrabody devices in near real time
US8886288B2 (en) 2009-06-16 2014-11-11 MRI Interventions, Inc. MRI-guided devices and MRI-guided interventional systems that can track and generate dynamic visualizations of the devices in near real time
US8882763B2 (en) 2010-01-12 2014-11-11 Greatbatch Ltd. Patient attached bonding strap for energy dissipation from a probe or a catheter during magnetic resonance imaging
US10561837B2 (en) 2011-03-01 2020-02-18 Greatbatch Ltd. Low equivalent series resistance RF filter for an active implantable medical device utilizing a ceramic reinforced metal composite filled via
US10596369B2 (en) 2011-03-01 2020-03-24 Greatbatch Ltd. Low equivalent series resistance RF filter for an active implantable medical device
US11071858B2 (en) 2011-03-01 2021-07-27 Greatbatch Ltd. Hermetically sealed filtered feedthrough having platinum sealed directly to the insulator in a via hole
US11198014B2 (en) 2011-03-01 2021-12-14 Greatbatch Ltd. Hermetically sealed filtered feedthrough assembly having a capacitor with an oxide resistant electrical connection to an active implantable medical device housing
USRE46699E1 (en) 2013-01-16 2018-02-06 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
US9427596B2 (en) 2013-01-16 2016-08-30 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
US9931514B2 (en) 2013-06-30 2018-04-03 Greatbatch Ltd. Low impedance oxide resistant grounded capacitor for an AIMD
US10350421B2 (en) 2013-06-30 2019-07-16 Greatbatch Ltd. Metallurgically bonded gold pocket pad for grounding an EMI filter to a hermetic terminal for an active implantable medical device
US10589107B2 (en) 2016-11-08 2020-03-17 Greatbatch Ltd. Circuit board mounted filtered feedthrough assembly having a composite conductive lead for an AIMD
US10559409B2 (en) 2017-01-06 2020-02-11 Greatbatch Ltd. Process for manufacturing a leadless feedthrough for an active implantable medical device
US10905888B2 (en) 2018-03-22 2021-02-02 Greatbatch Ltd. Electrical connection for an AIMD EMI filter utilizing an anisotropic conductive layer
US10912945B2 (en) 2018-03-22 2021-02-09 Greatbatch Ltd. Hermetic terminal for an active implantable medical device having a feedthrough capacitor partially overhanging a ferrule for high effective capacitance area
US11712571B2 (en) 2018-03-22 2023-08-01 Greatbatch Ltd. Electrical connection for a hermetic terminal for an active implantable medical device utilizing a ferrule pocket

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