WO1998046270A3 - Molecules presentant une pluralite de groupes fonctionnels actifs - Google Patents
Molecules presentant une pluralite de groupes fonctionnels actifs Download PDFInfo
- Publication number
- WO1998046270A3 WO1998046270A3 PCT/US1998/007171 US9807171W WO9846270A3 WO 1998046270 A3 WO1998046270 A3 WO 1998046270A3 US 9807171 W US9807171 W US 9807171W WO 9846270 A3 WO9846270 A3 WO 9846270A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polyvalent
- methods
- presenters
- presenter
- polyvalently
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/00756—Compositions, e.g. coatings, crystals, formulations
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP54407498A JP2002503223A (ja) | 1997-04-11 | 1998-04-09 | 複数の活性分子を供与する分子 |
KR1019997009364A KR20010006280A (ko) | 1997-04-11 | 1998-04-09 | 다수개의 활성 잔기를 제공하는 분자 |
EP98918079A EP0973551A2 (fr) | 1997-04-11 | 1998-04-09 | Molecules presentant une pluralite de groupes fonctionnels actifs |
BR9808521-2A BR9808521A (pt) | 1997-04-11 | 1998-04-09 | Moléculas que apresentam um grande número de partes ativas. |
CA002286692A CA2286692A1 (fr) | 1997-04-11 | 1998-04-09 | Molecules presentant une pluralite de groupes fonctionnels actifs |
AU71069/98A AU743028B2 (en) | 1997-04-11 | 1998-04-09 | Molecules presenting a multitude of active moieties |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4378197P | 1997-04-11 | 1997-04-11 | |
US60/043,781 | 1997-04-11 | ||
US4382697P | 1997-04-14 | 1997-04-14 | |
US60/043,826 | 1997-04-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998046270A2 WO1998046270A2 (fr) | 1998-10-22 |
WO1998046270A3 true WO1998046270A3 (fr) | 1999-01-07 |
Family
ID=26720814
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/007171 WO1998046270A2 (fr) | 1997-04-11 | 1998-04-09 | Molecules presentant une pluralite de groupes fonctionnels actifs |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0973551A2 (fr) |
JP (1) | JP2002503223A (fr) |
KR (1) | KR20010006280A (fr) |
CN (1) | CN1269013A (fr) |
AU (1) | AU743028B2 (fr) |
BR (1) | BR9808521A (fr) |
CA (1) | CA2286692A1 (fr) |
WO (1) | WO1998046270A2 (fr) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2330611A1 (fr) | 1998-05-22 | 1999-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Molecules bifonctionnelles et therapies basees sur celles-ci |
JP3468149B2 (ja) * | 1999-02-19 | 2003-11-17 | 松下電器産業株式会社 | 微細物体の操作装置および操作方法 |
EP1177029B1 (fr) * | 1999-05-10 | 2004-03-17 | Glaxo Group Limited | Station de travail haute capacite de criblage de formes cristallines et son utilisation |
US6887842B1 (en) | 1999-11-19 | 2005-05-03 | The Board Of Trustees Of The Leland Stanford Junior University | Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug |
US7220552B1 (en) | 1999-11-19 | 2007-05-22 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional molecules and their use in the disruption of protein-protein interactions |
WO2001035978A1 (fr) | 1999-11-19 | 2001-05-25 | The Board Of Trustees Of The Leland Stanford Junior University | Molecules bifonctionnelles ciblees et therapies basees sur celles-ci |
EG24716A (en) | 2002-05-17 | 2010-06-07 | Novartis Ag | Combination of organic compounds |
KR100543171B1 (ko) * | 2002-05-31 | 2006-01-20 | 한국과학기술원 | 분자수준에서 배향성을 조절하면서 항체 단분자막을 제조하는 방법 |
CA2583666A1 (fr) * | 2004-10-13 | 2006-04-27 | Ilypsa, Inc. | Preparations pharmaceutiques comprenant un oligosaccharide complexant les toxines et une particule polymere |
CN101325963B (zh) | 2005-10-08 | 2016-01-27 | 博泰迪亚制药公司 | 用于眼部病症的补体抑制素和其类似物 |
ES2545775T3 (es) | 2007-02-05 | 2015-09-15 | Apellis Pharmaceuticals, Inc. | Análogos de compstatina para uso en el tratamiento de afecciones inflamatorias del sistema respiratorio |
EP2139524A1 (fr) * | 2007-03-23 | 2010-01-06 | The Governors of the University of Alberta | Polymères hétérobifonctionnels multivalents et leurs procédés d'utilisation |
EP2192923A2 (fr) * | 2007-08-27 | 2010-06-09 | Massachusetts Institute of Technology | Inhibiteurs du virus de la grippe couplés à un polymère bifonctionnel |
CN107050422B (zh) | 2011-05-11 | 2021-11-09 | 阿佩利斯制药公司 | 细胞反应性的、长效的或靶向的坎普他汀类似物及其用途 |
MX363606B (es) | 2011-06-22 | 2019-03-28 | Apellis Pharmaceuticals Inc | Uso de inhibidores del complemento en trastornos crónicos. |
SI3660033T1 (sl) | 2012-11-15 | 2021-09-30 | Apellis Pharmaceuticals, Inc. | Analogi kompstatina z dolgotrajnim delovanjem in sorodni sestavki in postopki |
WO2014134297A1 (fr) * | 2013-02-28 | 2014-09-04 | The University Of Southern Mississippi | Liaison covalente de bactériophages à des surfaces polymères |
RU2770099C2 (ru) | 2015-10-07 | 2022-04-14 | Апеллис Фармасьютикалс, Инк. | Схемы введения |
KR20210084552A (ko) | 2018-10-29 | 2021-07-07 | 위스콘신 얼럼나이 리서어치 화운데이션 | 향상된 암 면역요법을 위한 면역관문 억제제와 복합체화된 덴드리틱 폴리머 |
US11564995B2 (en) | 2018-10-29 | 2023-01-31 | Wisconsin Alumni Research Foundation | Peptide-nanoparticle conjugates |
KR20220092557A (ko) | 2019-10-29 | 2022-07-01 | 위스콘신 얼럼나이 리서어치 화운데이션 | 펩티드-나노입자 접합체 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990010023A1 (fr) * | 1989-03-01 | 1990-09-07 | Biocarb Ab | Copolymeres a base d'acrylglucides et de methacrylglucides ainsi que leur fabrication |
WO1998014215A2 (fr) * | 1996-10-02 | 1998-04-09 | Syntesome Gesellschaft Für Med. Biochemie M.B.H. | Glyconconjugues comme inhibiteurs d'adherence cellulaire virale |
-
1998
- 1998-04-09 WO PCT/US1998/007171 patent/WO1998046270A2/fr not_active Application Discontinuation
- 1998-04-09 CA CA002286692A patent/CA2286692A1/fr not_active Abandoned
- 1998-04-09 JP JP54407498A patent/JP2002503223A/ja active Pending
- 1998-04-09 CN CN98804085A patent/CN1269013A/zh active Pending
- 1998-04-09 AU AU71069/98A patent/AU743028B2/en not_active Ceased
- 1998-04-09 EP EP98918079A patent/EP0973551A2/fr not_active Withdrawn
- 1998-04-09 KR KR1019997009364A patent/KR20010006280A/ko not_active Application Discontinuation
- 1998-04-09 BR BR9808521-2A patent/BR9808521A/pt not_active IP Right Cessation
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1990010023A1 (fr) * | 1989-03-01 | 1990-09-07 | Biocarb Ab | Copolymeres a base d'acrylglucides et de methacrylglucides ainsi que leur fabrication |
WO1998014215A2 (fr) * | 1996-10-02 | 1998-04-09 | Syntesome Gesellschaft Für Med. Biochemie M.B.H. | Glyconconjugues comme inhibiteurs d'adherence cellulaire virale |
Non-Patent Citations (13)
Also Published As
Publication number | Publication date |
---|---|
JP2002503223A (ja) | 2002-01-29 |
CN1269013A (zh) | 2000-10-04 |
KR20010006280A (ko) | 2001-01-26 |
CA2286692A1 (fr) | 1998-10-22 |
BR9808521A (pt) | 2000-05-23 |
AU743028B2 (en) | 2002-01-17 |
WO1998046270A2 (fr) | 1998-10-22 |
EP0973551A2 (fr) | 2000-01-26 |
AU7106998A (en) | 1998-11-11 |
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