WO1998023297A3 - Compositions particulaires - Google Patents

Compositions particulaires Download PDF

Info

Publication number
WO1998023297A3
WO1998023297A3 PCT/GB1997/003283 GB9703283W WO9823297A3 WO 1998023297 A3 WO1998023297 A3 WO 1998023297A3 GB 9703283 W GB9703283 W GB 9703283W WO 9823297 A3 WO9823297 A3 WO 9823297A3
Authority
WO
WIPO (PCT)
Prior art keywords
vesicles
particulate compositions
aqueous medium
contrast agent
ray contrast
Prior art date
Application number
PCT/GB1997/003283
Other languages
English (en)
Other versions
WO1998023297A2 (fr
Inventor
Liv Ingrid Oedegaardstuen
Kari Dyvik
Kathrin Bjerknes
Anne Kjersti Fahlvik
Original Assignee
Nycomed Imaging As
Cockbain Julian
Liv Ingrid Oedegaardstuen
Kari Dyvik
Kathrin Bjerknes
Anne Kjersti Fahlvik
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As, Cockbain Julian, Liv Ingrid Oedegaardstuen, Kari Dyvik, Kathrin Bjerknes, Anne Kjersti Fahlvik filed Critical Nycomed Imaging As
Priority to AU51293/98A priority Critical patent/AU5129398A/en
Priority to JP52444098A priority patent/JP2001504837A/ja
Priority to EP97945974A priority patent/EP1009445A2/fr
Publication of WO1998023297A2 publication Critical patent/WO1998023297A2/fr
Publication of WO1998023297A3 publication Critical patent/WO1998023297A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0461—Dispersions, colloids, emulsions or suspensions
    • A61K49/0466—Liposomes, lipoprotein vesicles, e.g. HDL or LDL lipoproteins, phospholipidic or polymeric micelles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne une composition d'agent de contraste, de préférence un milieu de contraste radiographique, comprenant des vésicules en suspension dans un milieu aqueux, les dites vésicules et, éventuellement, le dit milieu acqueux, contenant un agent de contraste radiographique iodé, caractérisée en ce qu'une dose de la dite composition, comprenant 100 mgI refermés dans lesdites vésicules, ne contient pas plus de 8x1012 vésicules.
PCT/GB1997/003283 1996-11-29 1997-11-28 Compositions particulaires WO1998023297A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU51293/98A AU5129398A (en) 1996-11-29 1997-11-28 Particulate compositions
JP52444098A JP2001504837A (ja) 1996-11-29 1997-11-28 粒状組成物
EP97945974A EP1009445A2 (fr) 1996-11-29 1997-11-28 Compositions particulaires

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9624918.0 1996-11-29
GBGB9624918.0A GB9624918D0 (en) 1996-11-29 1996-11-29 Particulate components

Publications (2)

Publication Number Publication Date
WO1998023297A2 WO1998023297A2 (fr) 1998-06-04
WO1998023297A3 true WO1998023297A3 (fr) 1998-07-16

Family

ID=10803721

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1997/003283 WO1998023297A2 (fr) 1996-11-29 1997-11-28 Compositions particulaires

Country Status (5)

Country Link
EP (1) EP1009445A2 (fr)
JP (1) JP2001504837A (fr)
AU (1) AU5129398A (fr)
GB (1) GB9624918D0 (fr)
WO (1) WO1998023297A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO20004795D0 (no) 2000-09-26 2000-09-26 Nycomed Imaging As Peptidbaserte forbindelser
DE602007012693D1 (de) * 2006-05-26 2011-04-07 Baxter Healthcare Sa Injizierbare fibrin-zusammensetzung zur knochenverstärkung
WO2011117236A1 (fr) * 2010-03-23 2011-09-29 Ge Healthcare As Préparation d'une composition diagnostique radiographique stabilisée
EP2606912A1 (fr) * 2011-12-23 2013-06-26 Central Medical Service Co., Ltd. Composition de substance de contraste avec effet d'amélioration de contraste comprenant un agent hautement concentré

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989011272A1 (fr) * 1988-05-20 1989-11-30 The Liposome Company, Inc. Complexe agent actif:lipide a rapport eleve
WO1992010166A1 (fr) * 1990-12-11 1992-06-25 Sintetica S.A. Procede de production de liposomes a capacite accrue de piegeage des substances etrangeres a encapsuler
WO1995026205A1 (fr) * 1994-03-28 1995-10-05 Nycomed Imaging A/S Liposomes
WO1995026185A1 (fr) * 1994-03-28 1995-10-05 Daiichi Pharmaceutical Co., Ltd. Liposome a capacite de retention accrue
WO1996024381A2 (fr) * 1995-02-09 1996-08-15 Schering Aktiengesellschaft Liposomes contenant des agents de contraste pour l'imagerie relative au pool sanguin intracardiaque
WO1996025955A1 (fr) * 1995-02-24 1996-08-29 Bracco Research S.A. Suspensions de liposomes utilisees comme produit de contraste de visualisation du pool sanguin intracardiaque

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989011272A1 (fr) * 1988-05-20 1989-11-30 The Liposome Company, Inc. Complexe agent actif:lipide a rapport eleve
WO1992010166A1 (fr) * 1990-12-11 1992-06-25 Sintetica S.A. Procede de production de liposomes a capacite accrue de piegeage des substances etrangeres a encapsuler
WO1995026205A1 (fr) * 1994-03-28 1995-10-05 Nycomed Imaging A/S Liposomes
WO1995026185A1 (fr) * 1994-03-28 1995-10-05 Daiichi Pharmaceutical Co., Ltd. Liposome a capacite de retention accrue
EP0804925A1 (fr) * 1994-03-28 1997-11-05 Daiichi Pharmaceutical Co., Ltd. Liposome a capacite de retention accrue
WO1996024381A2 (fr) * 1995-02-09 1996-08-15 Schering Aktiengesellschaft Liposomes contenant des agents de contraste pour l'imagerie relative au pool sanguin intracardiaque
WO1996025955A1 (fr) * 1995-02-24 1996-08-29 Bracco Research S.A. Suspensions de liposomes utilisees comme produit de contraste de visualisation du pool sanguin intracardiaque

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HENZE A ET AL: "RADIO-OPAQUE LIPOSOMES FOR THE IMPROVED VISUALISATION OF FOCAL LIVER DISEASE BY COMPUTERIZED TOMOGRAPHY", COMPUTERIZED MEDICAL IMAGING AND GRAPHICS, vol. 13, no. 6, 1989, pages 455 - 462, XP002049028 *
KRAUSE, W. ET AL: "Liposomes in diagnostic imaging: comparison of modalities; in vivo visualization of liposomes", JOURNAL OF LIPOSOME RESEARCH, vol. 5, no. 1, 1995, pages 1 - 27, XP002063540 *
LEANDER P.: "Liver specific contrast media for MRI and CT. Experimental studies", ACTA RADIOLOGICA SUPPLEMENTUM, vol. 36, no. supp. 396, 1995, pages 1 - 36, XP002063541 *

Also Published As

Publication number Publication date
JP2001504837A (ja) 2001-04-10
WO1998023297A2 (fr) 1998-06-04
AU5129398A (en) 1998-06-22
EP1009445A2 (fr) 2000-06-21
GB9624918D0 (en) 1997-01-15

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