WO1998015522A3 - Procede de preparation de derives de trans-4-(4-aminomethylphenyl)cyclohexanols - Google Patents

Procede de preparation de derives de trans-4-(4-aminomethylphenyl)cyclohexanols Download PDF

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Publication number
WO1998015522A3
WO1998015522A3 PCT/FR1997/001749 FR9701749W WO9815522A3 WO 1998015522 A3 WO1998015522 A3 WO 1998015522A3 FR 9701749 W FR9701749 W FR 9701749W WO 9815522 A3 WO9815522 A3 WO 9815522A3
Authority
WO
WIPO (PCT)
Prior art keywords
aminomethylphenyl
preparing trans
cyclohexanol derivatives
branched
linear
Prior art date
Application number
PCT/FR1997/001749
Other languages
English (en)
Other versions
WO1998015522A2 (fr
Inventor
Guy Adrian
Sylviane Mignonac
Lamer Valerie De
Original Assignee
Synthelabo
Guy Adrian
Sylviane Mignonac
Lamer Valerie De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo, Guy Adrian, Sylviane Mignonac, Lamer Valerie De filed Critical Synthelabo
Priority to AU45593/97A priority Critical patent/AU4559397A/en
Publication of WO1998015522A2 publication Critical patent/WO1998015522A2/fr
Publication of WO1998015522A3 publication Critical patent/WO1998015522A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/70—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/84—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups and doubly-bound oxygen atoms bound to the same carbon skeleton with the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procédé de préparation de dérivés de trans-4-(4-aminométhylphényl)cyclohexanols de formule (I), dans laquelle R1 et R2 représentent, indépendamment l'un de l'autre, un groupe C1-6 alkyle, linéaire ou ramifié, un groupe benzyle ou un groupe phényle éventuellement substitué par un ou deux substituants tels qu'un groupe C1-4 alkyle, linéaire ou ramifié, ou un halogène, tel qu'un fluor, un chlore, un brome ou un iode.
PCT/FR1997/001749 1996-10-08 1997-10-03 Procede de preparation de derives de trans-4-(4-aminomethylphenyl)cyclohexanols WO1998015522A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU45593/97A AU4559397A (en) 1996-10-08 1997-10-03 Method for preparing trans-4-(4-aminomethylphenyl) cyclohexanol derivatives

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9612227A FR2754255B1 (fr) 1996-10-08 1996-10-08 Procede de preparation de derives de trans-4-(4- aminomethylphenyl) cyclohexanols
FR96/12227 1996-10-08

Publications (2)

Publication Number Publication Date
WO1998015522A2 WO1998015522A2 (fr) 1998-04-16
WO1998015522A3 true WO1998015522A3 (fr) 2002-10-10

Family

ID=9496447

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR1997/001749 WO1998015522A2 (fr) 1996-10-08 1997-10-03 Procede de preparation de derives de trans-4-(4-aminomethylphenyl)cyclohexanols

Country Status (3)

Country Link
AU (1) AU4559397A (fr)
FR (1) FR2754255B1 (fr)
WO (1) WO1998015522A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102093168B (zh) * 2010-12-03 2013-08-07 西安瑞联近代电子材料有限责任公司 4-（反-4’-正烷基环己基）环己醇异构化方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4412692A1 (de) * 1994-04-13 1995-10-19 Thomae Gmbh Dr K Cycloalkanonoxime, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
WO1995029148A1 (fr) * 1992-11-20 1995-11-02 Dr. Karl Thomae Gmbh O-acyl-4-phenyl-cyclohexanols, leurs sels, medicaments contenant ces composes et leur utilisation, ainsi que leur procede de fabrication

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995029148A1 (fr) * 1992-11-20 1995-11-02 Dr. Karl Thomae Gmbh O-acyl-4-phenyl-cyclohexanols, leurs sels, medicaments contenant ces composes et leur utilisation, ainsi que leur procede de fabrication
DE4412692A1 (de) * 1994-04-13 1995-10-19 Thomae Gmbh Dr K Cycloalkanonoxime, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
FR2754255B1 (fr) 1998-10-30
AU4559397A (en) 1998-05-05
FR2754255A1 (fr) 1998-04-10
WO1998015522A2 (fr) 1998-04-16

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