WO1998008467A1 - Implant orthopedique modulaire reglable - Google Patents

Implant orthopedique modulaire reglable Download PDF

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Publication number
WO1998008467A1
WO1998008467A1 PCT/US1996/016246 US9616246W WO9808467A1 WO 1998008467 A1 WO1998008467 A1 WO 1998008467A1 US 9616246 W US9616246 W US 9616246W WO 9808467 A1 WO9808467 A1 WO 9808467A1
Authority
WO
WIPO (PCT)
Prior art keywords
stem
prosthesis
channel
component
articulating
Prior art date
Application number
PCT/US1996/016246
Other languages
English (en)
Inventor
Douglas Hunter Powell
Original Assignee
Hunter Innovations, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/706,406 external-priority patent/US5876459A/en
Application filed by Hunter Innovations, Inc. filed Critical Hunter Innovations, Inc.
Priority to AU74374/96A priority Critical patent/AU7437496A/en
Priority to PCT/US1996/016246 priority patent/WO1998008467A1/fr
Priority claimed from US08/885,674 external-priority patent/US5906644A/en
Priority to PCT/US1997/015047 priority patent/WO1998008468A1/fr
Priority to AU40927/97A priority patent/AU4092797A/en
Publication of WO1998008467A1 publication Critical patent/WO1998008467A1/fr

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    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
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    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389The prosthesis being coated or covered with a particular material
    • A61F2310/00592Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite

Definitions

  • This invention relates generally to modular implantable orthopedic prostheses, and particularly those which are adjustable in size to fit a given patient's needs.
  • Various prostheses have heretofore been designed to replace one or both components of a ball and socket hip joint.
  • the ball portion is connected to an arm composed of a neck and a stem or shaft which stem or shaft is embedded in the intramedullary canal of the proximal femur for hip reconstruction.
  • Such prostheses are often formed with an integral stem and neck portion.
  • a removable ball or head element is positioned on the proximal end of the neck. See, for example, U.S. Patent Numbers 4,012, 795 or 4,459, 708.
  • U. S. Patent No. 5, 108,452 to Fallin shows a modular hip having extension sleeves to adjust the length between the ball and neck as well as additional pads to increase the cross-sectional shape of the prosthesis body.
  • U.S. Patent No. 4,878,917 to Kranz et al. discloses a modular hip prosthesis having a stem with a distal tip that is radially expandable to anchor the stem against the medullary canal wall.
  • U. S. Patent No. 4,846,839 to Noiles discloses a modular prosthesis design, alternatively adaptable to either total hip or knee arthroplasty, which presents a stepped contour interface with the patient's bone.
  • the components of this design are connected via conventional Morse tapers.
  • a further type of device used for the fixation of modular prosthesis components is sold by H. D. Holmes under the registered trademark Spiralock®, consisting of a clamping screw which fastens a standard Morse taper connection together, e. g., connecting either the tibial tray or femoral component of a total knee joint to its respective stem.
  • Spiralock® consisting of a clamping screw which fastens a standard Morse taper connection together, e. g., connecting either the tibial tray or femoral component of a total knee joint to its respective stem.
  • a further example of the use of such locking screws in a modular hip prosthesis is found in U. S. Patent No. 5,3
  • U. S. Patent No. 5,405,398 to Buford, III et al. discloses a knee prosthesis with a femoral component having a pin including a split ring which expands to keep the pin in place.
  • U. S. Patent Nos. 5,531, 792 to Huene and 4,011,602 to Rybicki, et al. each show bone fixation plugs having radially expanding members to apply compressive forces against the surrounding bone and promote ingrowth of the tissue into the member. Neither of these contemplate an improved mechanism for connecting the components of modular orthopedic implants of the type used in large or small total joint arthroplasty.
  • the modular knee and hip joint prostheses address the need for either or both the ball component or trochanteral module component to be removed if replacement becomes necessary, without extraction of the stem from the bone canal.
  • Different size balls or trochanteral components could also be substituted should the surgeon decide that such revision is necessary after a period of time.
  • These conventional devices also contemplate selecting from a variety of sizes of their components, in order to match the anatomy of a given patient as closely as possible within the inherent variability of the assembly.
  • the modular systems notwithstanding the variability offered in their assemblage of specifically sized components, fail to provide an infinite variability within a given size range while creating a biomechanical assembly of enhanced strength. That is, the prior assemblies introduce tors ⁇ onal stresses at the junctures of their components which do not necessarily reflect a unitary construction. Moreover, a wide array of sizes must be kept in stock during surgery to match a patient's anatomy.
  • an implantable modular orthopedic prosthesis which consists of three components.
  • a first component has an elongated stem with a free end, configured to be situated within the intramedullary canal of a patient's bone, and an opposite end having an articulating portion.
  • a second component has another articulating portion which is matingly engageable with the articulating portion of the first component.
  • a third component has a body with a linearly-extruded channel through which the articulating portions are adjustably received, wherein at least one of the components is radially-expansible to pressure lock against an internal surface of the channel in a selected position and arrest the first, second and third components together as the articulating portions are fully engaged with one another.
  • the prosthesis is a modular hip, while in another preferred embodiment it is a modular knee, particularly, a tibial prosthesis.
  • the articulating portions are complementary Morse-tapered connectors.
  • a tensioning member urges the articulating portions together, causing the radially-expanding component to pressure-lock against the internal surface of the channel and affix the three components together.
  • the radial-expansion take the form of a split collet mechanism.
  • An advantage of the present invention is an improved mechanism for interlocking the components of a modular orthopedic prosthesis which, following implantation, functions as a unitary biomechanical structure.
  • Another advantage of the present invention is a prosthetic system which is easy to use and interoperatively adjustable to fit minute variations in a patient's given anatomy, while minimizing the inventory of component sizes needed on hand during surgery.
  • FIG. 1 is an exploded perspective view of the components of the invention embodied in a preferred modular hip prosthesis, with the components positioned for maximum stem extension;
  • FIG. 2 is an external top view of the prosthesis of FIG. 1;
  • FIG. 3 is a longitudinal sectional view of the prosthesis of FIG. 2, taken along the lines 3-3;
  • FIG. 4 is a perspective view of the hip prosthesis of FIG. 1, shown fully assembled with the stem component in its fully extended position;
  • FIG. 5 is an exploded perspective view of the components of the invention embodied in a preferred modular hip prosthesis, with the components positioned for minimal stem extension;
  • FIG. 6 is an external top view of the prosthesis of FIG. 5;
  • FIG. 7 is a longitudinal sectional view of the prosthesis of FIG. 5, taken aiong the lines 7-7 of FIG. 6;
  • FIG. 8 is a perspective view of the hip prosthesis of FIG. 1, shown fully assembled with the stem component in its minimally extended position;
  • FIG, 9 is a longitudinal sectional view of the prosthesis of FIG. 8, taken along the lines 9-9;
  • FIG. 10 is a side view of the hip prosthesis of FIG. 1, shown fully assembled with the stem component in its minimally extended position;
  • FIG. 11 is a transverse sectional view of the hip prosthesis of FIG. 8, taken along the lines 11-11, showing the preferred expanded collet mechanism of the invention located on the stem:
  • FIG. 12 is a side view of the preferred hip prosthesis of the invention, shown in an assembled state with the stem in its maximally-extended position and the trochanteric module rotated to an alternative conformation;
  • FIG. 13 is an exploded perspective view of the components of the invention embodied in a preferred modular hip prosthesis, with the expanding collet mechanism located on the neck:
  • FIG. 14 is a longitudinal sectional view of the prosthesis of FIG. 13, taken along the lines 14-14;
  • FIG. 15 is a perspective view of the hip prosthesis of FIG. 13, shown fully assembled with the stem component in its minimally extended position;
  • FIG. 16 is a longitudinal sectional view of the prosthesis of FIG. 15, taken along the lines 16-16;
  • FIG. 17 is a perspective view of the hip prosthesis of FIG. 13, shown fully assembled with the stem component in its maximally extended position;
  • FIG. 18 is a longitudinal sectional view of the prosthesis of FIG. 17, taken along the lines 17-17;
  • FIG. 19 is an exploded perspective view of the components of the invention embodied in a preferred modular tibial prosthesis, with the expanding collet mechanism located on the stem;
  • FIG. 20 is a longitudinal sectional view of the tibial prosthesis of FIG. 19, taken along the lines 20-20;
  • FIG. 21 is a perspective view of the tibial prosthesis of FIG. 19, shown fully assembled with the stem component in its minimally extended position;
  • FIG. 22 is a perspective view of the tibial prosthesis of FIG. 19, shown fully assembled with the stem component in its maximally extended position;
  • FIG. 23 is a side view of the prosthesis of FIG. 19, shown in an assembled state with the stem in its maximally-extended position and its transition module proximally abutting the distal surface of the tray;
  • FIG. 24 is an external top view of the tibial prosthesis of FIG. 23;
  • FIG. 25 is a longitudinal sectional view of the tibial prosthesis of FIG. 23, taken along the lines 7-7 of FIG. 24;
  • FIG. 26 is a side view of the prosthesis of FIG. 19, shown in an assembled state with the stem in its minimally-extended position and its transition module spaced from the distal surface of the tray;
  • FIG. 27 is an external top view of the tibial prosthesis of FIG. 26.
  • FIG. 28 is a longitudinal sectional view of the tibial prosthesis of FIG. 26, taken along the lines 28-28 of FIG. 27.
  • an implantable modular orthopedic prosthesis in this case a hip prosthesis, generally shown at 10, which is comprised of multiple components.
  • a first component is an elongated stem, generally shown at 12, with a free distal end 14, configured to be situated within the intramedullary canal of a patient's bone (not shown), and an opposite end, generally indicated at 16, having an articulating portion, preferably a Morse-tapered connecting member, such as the frusto-conical bore 18.
  • a second component is a neck, generally shown at 20, which has another articulating portion, preferably a complementary Morse-tapered connector such as the tapered post 22, which is matingly engageable with the tapered bore 18 of the stem 12.
  • a third component is a trochanteric module, generally indicated at 24 having a contoured body 26 adapted for implantation into the resected proximal femur of a patient.
  • a linearly-extruded channel 28 is formed through the module 24, along an axis A (Fig. 1) generally coincident with the longitudinal axis of the stem 12, with an internal surface 30.
  • the articulating portions 18,22 are adjustably received within the channel 28, such that the module 24 can be axially moved along axis A relative to stem 12 and neck 20 to adjust the distance between the module and the neck and stem, respectively.
  • At least one of the components is radially-expansible, preferably by means of the expanding collet mechanism 32 to pressure lock against the internal surface 30 of the channel 28 in a selected position and arrest the first (stem 12), second (neck 20) and third (module 24) components together as the articulating portions, i. e., tapered bore 18 and post 22, are fully engaged with one another.
  • the tapered bore 18 and collet 32 are shown in Figs. 12 as being located on the stem 12, the location of these elements may be reversed so that they are on the neck, as will be described hereinafter with reference to Figs. 13-18.
  • the hip prosthesis 10 further comprises a tensioning member, generally indicated at 34, operatively connecting the stem 12 and neck 20, to urge the articulating Morse-tapered bore 18 and post 22 together and affix all three components 12, 20, 24 of the prosthesis 10 together in a desired relative conformation.
  • a tensioning member generally indicated at 34, operatively connecting the stem 12 and neck 20, to urge the articulating Morse-tapered bore 18 and post 22 together and affix all three components 12, 20, 24 of the prosthesis 10 together in a desired relative conformation.
  • the tensioning member preferably consists of a locking bolt 34 having an elongated shaft 36 with a driven end 38 and a threaded end 40 which passes distally through an opening 42 formed in the neck 20, thence through the tapered post 18 and bore 22 to threaded ly engage a tapped aperture 44 in the stem 12.
  • the bolt 34 could alternatively be passed through an opening optionally formed in the distal end 14 of the stem 12 (not shown) and continuing proximally to engage a threaded aperture in the neck (not shown), as will be appreciated by those skilled in the art.
  • the linearly extruded channel 28 preferably has a circular cross section, e. g., a cylindrical bore, allowing infinitely variable rotational adjustment of the stem 12 and neck 20 relative to one another, and allowing proximal-distal adjustment of these components within the channel 28.
  • the channel 28 may alternatively have a polygonal cross section or a star shape (not shown) while the articulating portions could have corresponding shapes which would be respectively indexable relative to the channel in a finite selection of rotational alignments, rather than the infinite rotational adjustability afforded by the Morse-tapered connection described herein.
  • Having a square shaped channel (not shown), for example, would allow for 4 orthogonal relative rotations of the neck 20 and stem 12, while the multi-point star shape would allow for multiple rotations of the neck and stem.
  • the linearly extruded cut of the channel 28 also allows for the independent insertion, rotation and removal of the stem 12 without removing the anatomically press fit trochanteric module 24, once implanted. Though inserting the stem 12 from the proximal end of the neck has its advantages, inserting the stem from the distal direction proximally into the neck, prior to insertion into the femoral bone allows for greater mechanical stability and variable design flexibility.
  • the body 26 of trochanteric module 24 has a proximal shoulder 46 which abuts a stop 48 formed on the neck 20, limiting the range of axially adjustable telescoping movement of the surrounding trochanteric module 24 relative to the neck and stem 12, prior to full engagement of the articulating bore 18 and post 22 by tightening of the bolt 34.
  • Module 24 has a rounded triangular cross section, adjacent the proximal shoulder 46, the area of which reduces distally, shown, e. g., in Figs. 10-1 1.
  • the neck 20 is equipped with an integral, angulated member 21 with a further Morse-tapered post 23 for attachment of a conventional ball (not shown).
  • Fig. 4 the prosthesis 10 is shown with the stem 12 in its maximally extended position, that is, the shoulder 46 abuts the stop 48 with the components 12, 20, 24 affixed together.
  • the collet 32 is fully constrained within the channel 28, as shown in Fig. 4 and also in Fig. 5 where the collet 32 is actuated within channel 28 to pressure-lock against internal surface 30 in a selected location such that the shoulder 46 is axially spaced from the distal stop 48.
  • a patient can be fitted with a fixed size of prosthetic components, then the sized components adapted to either increase (Fig 4) or decrease (Fig. 5) the effective length of the stem 12, depending upon the patient's anatomy, without resort to a more complex assortment of intermediate sizes of trial implants and prosthetic components.
  • FIG. I I shows the collet 32 expanded radially against the internal surface 30 in the direction of arrows 50, in the manner described above, i. e., by actuation of the locking bolt 34.
  • a hip prosthesis 10 of the present invention is shown having the trochanteric module 24 rotationally adjusted so that the portion of the body 26 which forms a transverse triangular faceted shaped member 52 forms a complex angle with the axis B of the ball post 23 and the axis A of the stem 12.
  • Figs. 13-18 show a prosthesis 10 with an alternative juxtaposition of the collet 32 and Morse- tapered bore 18 situated on the neck 20 rather than stem 12, and the tapered post 22 located on the proximal articulating portion of the stem 12.
  • the prosthesis 10 like the embodiment of Figs. 1-12, may be assembled either with stem 12 in a minimally extended (Figs. 15-16) or maximally extended (Figs. 17-18) conformation.
  • Morse tapered connections Traditional fixation mechanisms for modular implants typically use Morse tapered connections.
  • the Morse taper is designed to withstand compressive forces and rotational torque, but is not particularly well suited for tension forces and bending moments. It can be shown that bending moments induced on a Morse-tapered connection, where the independent components have dissimilar moments of inertia, can cause surface micro motion at the connection and hence wear, wear debris and eventual failure of the connection.
  • the fully contained radial expansion mechanism described herein, with reference to collet 32 transfers the bending moments induced on the implanted prosthesis 10, due to day to day activities, away from the articulating portions which connect the stem 12 and neck 20 components, toward the strongest portion of the prosthetic joint. Thus the expansion mechanism experiences much less stress than the interface of traditional taper connection modular hip stems.
  • the surgical procedure for preparing the patient to be implanted with the prosthesis 10 could be chosen from a variety of generally recognized methods and instrumentation, however, an example of a suitable technique is given in the aforementioned U. S. Patent No. 5,201,882 to Paxson. the entire disclosure of which is expressly incorporated by reference herein and relied upon.
  • the prosthesis 10 is a modular connection system for use in total joint arthroplasty. Therefore, the rotational and linear extension mechanism of the invention can readily be applied to knee, shoulder and hip joint replacement components each having similar characteristics and functional advantages as it relates to adjustable bone fixation.
  • a tibial prosthesis for use in total knee arthroplasty will be described below.
  • an implantable modular tibial prosthesis 1 10 is depicted, with an elongated stem 1 12 having a free distal end 1 14, configured to be situated within the intramedullary canal of a patient's bone, and an opposite end 1 16 having preferably a Morse- tapered bore 1 18.
  • a tibial tray 120 having another articulating portion in the form of a Morse- tapered post 122 matingly engageable with the tapered bore 1 18 of the stem 1 12, for attaching the tray 120 and stem 1 12 together in a selected fixed rotational conformation.
  • a transition module generally shown at 124, has a body 126 with a linearly-extruded channel 128 having an internal surface 130, through which the articulating tapered bore 1 18 and post 122 of the stem 1 12 and tray 120, respectively, are telescopically received.
  • the stem 1 12 is radially-expansible by means of an expanding collet mechanism 132 to pressure lock against the internal surface 130 of the channel 128 in a selected location to arrest the stem 1 12, tray 120 and transition module 124 together in a fixed axial and rotational relationship as the mating articulating connectors 1 18, 122 are fully engaged with one another.
  • a tensioning member such as the locking bolt 134, operatively connects the stem 1 12 and tray 120, to urge the tapered bore 1 18 and post 122 fully together to affix the tray, stem and transition module together in a desired relative conformation.
  • the locking bolt 134 has an elongated shaft 136 having a driven end 138 and a threaded end 140 which passes through an opening 142 formed in the tray 120 to threadedly engage a tapped aperture 144 in the stem 1 12.
  • the stem 1 12 of prosthesis 1 10 has a Morse-tapered bore 1 18 and the neck 120 has the complementary Morse-tapered post 122, respectively, these elements could be reversed (not shown), similar to the juxtaposition, described above in Figs. 1- 12 versus Figs. 13-18, for the hip prosthesis 10. That is, and although not shown in the Drawings, the tray 120 could have the radially expansible collet and tapered bore, rather than having them on the stem, to pressure lock against the internal surface of the channel.
  • Channel 128 formed in the transition module 124 preferably has a circular cross section, e. g., a cylindrical bore, allowing infinitely variable rotational adjustment of the tray and stem relative to one another, and allowing axial adjustment of the transition module relative to the engaged tray and stem.
  • the channel 128 could have a polygonal cross section and the articulating portions could have corresponding shapes which are respectively indexable relative to the channel in a finite selection of rotational alignments.
  • a shoulder 146 is formed on the transition module 124 which abuts a stop 148 formed on the tray 120, limiting the range of axially adjustable telescoping movement of the transition module relative to the tray and stem 1 12 prior to full engagement of the articulating portions 1 18, 122 thereof.
  • the transition module 124 Prior to tightening of the tapered bore 1 18 and post 122 together by turning bolt 134, the transition module 124 can be slid in either the proximal direction, to increase the effective length of the stem 1 12 by abutment of shoulder 146 with stop 148 (Figs. 22-25), or distally to decrease the stem length (Figs. 21 and 26-28) leaving the shoulder 146 spaced from stop 148.

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  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne une prothèse orthopédique modulaire implantable (10, 110), destinée de préférence à être utilisée dans l'arthroplastie de la hanche (10) ou du genou (110), cette prothèse étant constituée de trois composants (12, 20, 24; 112, 120, 124). Le premier composant comporte une partie arrière (12, 112) dotée d'une extrémité libre (14, 114), conçue pour être placée dans le canal intramédullaire de l'os d'un patient, et d'une extrémité opposée (16, 116) ayant une partie articulée telle qu'un élément en forme de cône Morse (18, 118). Un second composant (20, 120) possède une autre partie articulée qui peut également être un élément en forme de cône Morse correspondant (22, 122) venant en contact de façon à s'accoupler avec la partie articulée (18, 118) du premier composant (12, 112). Un troisième composant (24, 124) possède un corps (26, 126) pourvu d'un canal extrudé de manière linéaire (28, 128) dans lequel sont admises, de façon à pouvoir se régler, les parties articulées (18, 22; 118, 122). Au moins un des composants (12, 20; 112, 120) peut se dilater radialement (32, 132) et exercer une pression contre une surface interne (30, 130) du canal (28, 128) dans une position choisie et bloquer les premier (12, 112), deuxième (20, 120) et troisième composants (24, 124) de façon à ce que les parties articulées (18, 22; 118, 122) s'engagent totalement les unes dans les autres. L'implant orthopédique modulaire de l'invention (10,110) fonctionne comme une structure biomécanique unitaire et est simple à utiliser du fait qu'il peut se régler de manière peropératoire pour s'adapter à de faibles variations en fonction de l'anatomie du patient et qu'il est possible, en même temps, de réduire le nombre de tailles requises des composants à portée de main, lors d'une intervention.
PCT/US1996/016246 1996-08-30 1996-10-11 Implant orthopedique modulaire reglable WO1998008467A1 (fr)

Priority Applications (4)

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AU74374/96A AU7437496A (en) 1996-08-30 1996-10-11 Adjustable modular orthopedic implant
PCT/US1996/016246 WO1998008467A1 (fr) 1996-08-30 1996-10-11 Implant orthopedique modulaire reglable
PCT/US1997/015047 WO1998008468A1 (fr) 1996-08-30 1997-08-26 Prothese orthopedique modulaire reglable
AU40927/97A AU4092797A (en) 1996-08-30 1997-08-26 Adjustable modular orthopedic implant

Applications Claiming Priority (3)

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US08/706,406 US5876459A (en) 1996-08-30 1996-08-30 Adjustable modular orthopedic implant
PCT/US1996/016246 WO1998008467A1 (fr) 1996-08-30 1996-10-11 Implant orthopedique modulaire reglable
US08/885,674 US5906644A (en) 1996-08-30 1997-06-30 Adjustable modular orthopedic implant

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US6428578B2 (en) 1998-03-18 2002-08-06 Sct Incorporated Modular prosthesis and connector therefor
US8048163B2 (en) 2002-02-20 2011-11-01 Zimmer, Inc. Knee arthroplasty prosthesis
US9072605B2 (en) 2002-02-20 2015-07-07 Zimmer, Inc. Knee arthroplasty prosthesis
US7182786B2 (en) 2002-04-25 2007-02-27 Zimmer Technology, Inc. Modular bone implant, tool, and method
US7799086B2 (en) 2002-04-25 2010-09-21 Zimmer Technology, Inc. Modular bone implant, tools, and method
US8075628B2 (en) 2002-04-25 2011-12-13 Zimmer, Inc. Modular bone implant, tools, and method
US8241367B2 (en) 2002-04-25 2012-08-14 Zimmer, Inc. Modular bone implant, tool, and method
US7455695B2 (en) 2004-06-28 2008-11-25 Depuy Products, Inc. Modular prosthesis and locking nut therefor
US8048167B2 (en) 2005-08-30 2011-11-01 Depuy Products, Inc. Orthopaedic implant kit, orthopaedic surgery kit and associated method
US8690951B2 (en) 2005-11-18 2014-04-08 Zimmer, Gmbh Base platform for an artificial joint

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AU7437496A (en) 1998-05-14
AU4092797A (en) 1998-03-19
WO1998008468A1 (fr) 1998-03-05

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