WO1997046683A3 - Polynucleotides encoding secreted proteins - Google Patents

Polynucleotides encoding secreted proteins Download PDF

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Publication number
WO1997046683A3
WO1997046683A3 PCT/US1997/009878 US9709878W WO9746683A3 WO 1997046683 A3 WO1997046683 A3 WO 1997046683A3 US 9709878 W US9709878 W US 9709878W WO 9746683 A3 WO9746683 A3 WO 9746683A3
Authority
WO
WIPO (PCT)
Prior art keywords
human
secreted proteins
encoding secreted
polynucleotides encoding
clones
Prior art date
Application number
PCT/US1997/009878
Other languages
French (fr)
Other versions
WO1997046683A2 (en
Inventor
Kenneth Jacobs
John M Mccoy
Edward R Lavallie
Lisa A Racie
David Merberg
Maurice Treacy
Cheryl Evans
Michael Bowman
Vikki Spaulding
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Priority to EP97929838A priority Critical patent/EP0910638A2/en
Priority to AU33804/97A priority patent/AU3380497A/en
Priority to CA002256522A priority patent/CA2256522A1/en
Priority to JP10500884A priority patent/JP2001501455A/en
Publication of WO1997046683A2 publication Critical patent/WO1997046683A2/en
Publication of WO1997046683A3 publication Critical patent/WO1997046683A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides 13 clones 'AZ302-1' isolated from human colon; 'AU139-2', 'AU105-14', and 'AJ147-1' from human adult testes; 'AS268-1', 'AS264-3', 'AS301-2', 'AS162-1' and 'AS86-1' from human fetal brain; 'D147-17' from human PBMC ; '075-9' from human dendritic cells; 'AM262-11' from human fetal kidney and clone 'AR28-1' from human adult retina comprising polynucleotides encoding secreted proteins, using methods selective for cDNAs encoding secreted proteins.
PCT/US1997/009878 1996-06-07 1997-06-06 Polynucleotides encoding secreted proteins WO1997046683A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP97929838A EP0910638A2 (en) 1996-06-07 1997-06-06 Polynucleotide encoding secreted proteins
AU33804/97A AU3380497A (en) 1996-06-07 1997-06-06 Polynucleotide encoding secreted proteins
CA002256522A CA2256522A1 (en) 1996-06-07 1997-06-06 Polynucleotides encoding secreted proteins
JP10500884A JP2001501455A (en) 1996-06-07 1997-06-06 Polynucleotides encoding secreted proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65922496A 1996-06-07 1996-06-07
US08/659,224 1996-06-07

Publications (2)

Publication Number Publication Date
WO1997046683A2 WO1997046683A2 (en) 1997-12-11
WO1997046683A3 true WO1997046683A3 (en) 1998-05-07

Family

ID=24644568

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US1997/009878 WO1997046683A2 (en) 1996-06-07 1997-06-06 Polynucleotides encoding secreted proteins
PCT/US1997/009865 WO1997046682A2 (en) 1996-06-07 1997-06-06 Polynucleotides from human adult pbmc encoding secreted proteins

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/US1997/009865 WO1997046682A2 (en) 1996-06-07 1997-06-06 Polynucleotides from human adult pbmc encoding secreted proteins

Country Status (5)

Country Link
EP (1) EP0910638A2 (en)
JP (2) JP2001501455A (en)
AU (2) AU3568697A (en)
CA (1) CA2256522A1 (en)
WO (2) WO1997046683A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005509B1 (en) 1995-02-17 2006-02-28 Incyte Corporation Chemokine PANEC-1 polynucleotides and compositions and methods related thereto
US7265201B1 (en) 1995-06-23 2007-09-04 Millennium Pharmaceuticals, Inc. Human chemotactic cytokine
AU2451199A (en) * 1998-01-07 1999-07-26 Human Genome Sciences, Inc. 36 human secreted proteins
US7173005B2 (en) 1998-09-02 2007-02-06 Antyra Inc. Insulin and IGF-1 receptor agonists and antagonists
US6875741B2 (en) 1998-09-02 2005-04-05 Renuka Pillutla Insulin and IGF-1 receptor agonists and antagonists
EP1383793B1 (en) * 2000-03-29 2011-10-19 DGI BioTechnologies, L.L.C. Insulin and igf-1 receptor agonists and antagonists
CN111334469A (en) * 2020-03-27 2020-06-26 郑州鲲鹏健康科技有限公司 PBMC (peripheral blood mononuclear cell) in-vitro 3D (three-dimensional) methylcellulose agarose hydrogel culture medium and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5536637A (en) * 1993-04-07 1996-07-16 Genetics Institute, Inc. Method of screening for cDNA encoding novel secreted mammalian proteins in yeast

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
CALLARD R E ET AL: "AIMS OF THE BOOK", CYTOKINE FACTSBOOK, 1994, CALLARD R E;GEARING A J H, pages 2/3, 31 - 38, 64/65, 75/76, 97/98, 148 - 151, 252/253, XP002039160 *
ENG MONG LIM ET AL: "IDENTIFICATION OF MYCOBACTERIUM TUBERCULOSIS DNA SEQUENCES ENCODING EXPORTED PROTEINS BY USING PHOA GENE FUSIONS", JOURNAL OF BACTERIOLOGY, vol. 177, no. 1, 1 January 1995 (1995-01-01), pages 59 - 65, XP000560419 *
J. NATHANS: "69C1 human retina cDNA Tsp509I-cleaved sublibrary Homo sapiens cDNA not directional", EMBL DATABASE ENTRY HSW22546, ACCESSION NUMBER W22546, 9 May 1996 (1996-05-09), XP002046017 *
JACOBS K ET AL: "A NOVEL METHOD FOR ISOLATING EUKARYOTIC CDNA CLONES ENCODING SECRETED PROTEINS", JOURNAL OF CELLULAR BIOCHEMISTRY - SUPPLEMENT, vol. 21A, 10 March 1995 (1995-03-10), pages 19, XP002027246 *
K. A. JACOBS ET AL: "A genetic selection for isolating cDNAs encoding secreted proteins", GENE., vol. 198, 1 October 1997 (1997-10-01), AMSTERDAM NL, pages 289 - 296, XP002045919 *
L. HILLIER ET AL: "The WashU-Merck EST project. zo29g02.r1 stratagene colon(#937204) Homo sapiens cDNA clone 588338 5'", EMBL DATABASE ENTRY HSAA51630 , ACCESSION NUMBER AA151630, 15 December 1996 (1996-12-15), XP002046018 *
M. YOKOYAMA-KOBAYASHI ET AL: "A signal sequence detection system using secreted protease activity as an indicator", GENE., vol. 163, 1995, AMSTERDAM NL, pages 193 - 196, XP002046435 *
TASHIRO K ET AL: "SIGNAL SEQUENCE TRAP: A CLONING STRATEGY FOR SECRETED PROTEINS AND TYPE I MEMBRANE PROTEINS", SCIENCE, vol. 261, 30 July 1993 (1993-07-30), pages 600 - 603, XP000673204 *

Also Published As

Publication number Publication date
AU3380497A (en) 1998-01-05
WO1997046683A2 (en) 1997-12-11
JP2000515726A (en) 2000-11-28
CA2256522A1 (en) 1997-12-11
WO1997046682A2 (en) 1997-12-11
AU3568697A (en) 1998-01-05
JP2001501455A (en) 2001-02-06
WO1997046682A3 (en) 1998-03-12
EP0910638A2 (en) 1999-04-28

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