WO1997025052B1 - Compositions comprising pvp having an average molecular weight in the range of 3,000 to 14,000 daltons - Google Patents
Compositions comprising pvp having an average molecular weight in the range of 3,000 to 14,000 daltonsInfo
- Publication number
- WO1997025052B1 WO1997025052B1 PCT/GB1997/000069 GB9700069W WO9725052B1 WO 1997025052 B1 WO1997025052 B1 WO 1997025052B1 GB 9700069 W GB9700069 W GB 9700069W WO 9725052 B1 WO9725052 B1 WO 9725052B1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pvp
- compositions
- daltons
- range
- average molecular
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract 5
- 238000000034 method Methods 0.000 claims abstract 6
- 241000048284 Potato virus P Species 0.000 claims abstract 4
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims abstract 4
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims abstract 4
- 239000000243 solution Substances 0.000 claims abstract 4
- 238000001802 infusion Methods 0.000 claims abstract 3
- 239000007864 aqueous solution Substances 0.000 claims abstract 2
- 238000002360 preparation method Methods 0.000 claims abstract 2
- 239000003729 cation exchange resin Substances 0.000 claims 2
- 210000001519 tissues Anatomy 0.000 claims 2
- 238000000108 ultra-filtration Methods 0.000 claims 2
- 206010059484 Haemodilution Diseases 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 abstract 1
Abstract
The present invention relates to compositions for use in medicine, e.g. as infusion or surgical rinse solutions, and to processes for their preparation. The compositions of the invention comprise an aqueous solution of physiologically inert PVP having a weight average molecular weight in the range of from 3,000 to 14,000 daltons.
Claims
AMENDED CLAIMS
[received by the International Bureau on 21 October 1997 (21.10.97); original claim 12 amended; remaining claims unchanged (1 page)]
10. Use of a composition as claimed in any one of claims 1 to 8 in the manufacture of an infusion, haemodilution or surgical rinse solution.
11. A method of infusion or surgical rinsing of tissues of the human or non-human animal body whereby the tissues are perfused with a composition as claimed in any one of claims l to 8.
12. A process for the preparation of an aqueous solution of physiologically inert PVP as defined in claim 1, said process comprising the step of passing a PVP solution over a cation exchange resin, optionally followed by ultrafiltration.
13. A process as claimed in claim 12 wherein said cation exchange resin is a strong acid cation exchanger.
14. A process as claimed in claim 12 or claim 13 wherein ultrafiltration is carried out at a pressure of from 100 to 500 mm Hg.
15. A PVP solution obtainable by a process as claimed in any one of claims 12 to 14.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52499597A JP4245192B2 (en) | 1996-01-10 | 1997-01-09 | A composition comprising PVP having an average molecular weight of 3,000 to 14,000 daltons |
EP97900318A EP0873130B1 (en) | 1996-01-10 | 1997-01-09 | Compositions comprising pvp having an average molecular weight in the range of 7.000 to 12.000 daltons |
DE69728376T DE69728376T2 (en) | 1996-01-10 | 1997-01-09 | COMPOSITIONS CONTAINING PVP WITH A MEDIUM MOLECULAR WEIGHT OF 7000 TO 12000 DALTONS |
CA002242618A CA2242618C (en) | 1996-01-10 | 1997-01-09 | Compositions comprising ultrapure pvp having an average molecular weight in the range of 7,000 to 12,000 daltons |
US09/091,228 US6080397A (en) | 1996-01-10 | 1997-01-09 | Compositions comprising PVP having an average molecular weight in the range of 3.000 to 14.000 daltons |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9600426.2 | 1996-01-10 | ||
GBGB9600426.2A GB9600426D0 (en) | 1996-01-10 | 1996-01-10 | Compositions |
Publications (3)
Publication Number | Publication Date |
---|---|
WO1997025052A2 WO1997025052A2 (en) | 1997-07-17 |
WO1997025052A3 WO1997025052A3 (en) | 1997-12-18 |
WO1997025052B1 true WO1997025052B1 (en) | 1998-01-15 |
Family
ID=10786817
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1997/000069 WO1997025052A2 (en) | 1996-01-10 | 1997-01-09 | Compositions comprising pvp having an average molecular weight in the range of 3,000 to 14,000 daltons |
Country Status (7)
Country | Link |
---|---|
US (1) | US6080397A (en) |
EP (1) | EP0873130B1 (en) |
JP (1) | JP4245192B2 (en) |
DE (1) | DE69728376T2 (en) |
ES (1) | ES2218652T3 (en) |
GB (1) | GB9600426D0 (en) |
WO (1) | WO1997025052A2 (en) |
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---|---|---|---|---|
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WO2018175777A1 (en) * | 2017-03-22 | 2018-09-27 | Cormedix Inc. | Use of an injectable antimicrobial composition for the prevention and/or treatment of osteoarthritis |
US11738120B1 (en) | 2022-04-14 | 2023-08-29 | Cormedix Inc. | Synthesis of taurolidine, purity profiles and polymorphs |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4350156A (en) * | 1980-05-29 | 1982-09-21 | Japan Foundation For Artificial Organs | Method and apparatus for on-line filtration removal of macromolecules from a physiological fluid |
GB8328074D0 (en) * | 1983-10-20 | 1983-11-23 | Geistlich Soehne Ag | Chemical compositions |
GB8328111D0 (en) * | 1983-10-20 | 1983-11-23 | Geistlich Soehne Ag | Chemical compounds |
GB8426922D0 (en) * | 1984-10-24 | 1984-11-28 | Sandoz Ltd | Galenic formulation |
-
1996
- 1996-01-10 GB GBGB9600426.2A patent/GB9600426D0/en active Pending
-
1997
- 1997-01-09 JP JP52499597A patent/JP4245192B2/en not_active Expired - Lifetime
- 1997-01-09 ES ES97900318T patent/ES2218652T3/en not_active Expired - Lifetime
- 1997-01-09 DE DE69728376T patent/DE69728376T2/en not_active Expired - Lifetime
- 1997-01-09 WO PCT/GB1997/000069 patent/WO1997025052A2/en active IP Right Grant
- 1997-01-09 US US09/091,228 patent/US6080397A/en not_active Expired - Lifetime
- 1997-01-09 EP EP97900318A patent/EP0873130B1/en not_active Expired - Lifetime
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