WO1996040087A3 - Composition acrylique adhesive sensible a la pression reticulee avec de l'acetylacetonate d'aluminium et contenant un medicament qui renferme un groupe hydroxy aromatique reactif - Google Patents

Composition acrylique adhesive sensible a la pression reticulee avec de l'acetylacetonate d'aluminium et contenant un medicament qui renferme un groupe hydroxy aromatique reactif Download PDF

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Publication number
WO1996040087A3
WO1996040087A3 PCT/US1996/008492 US9608492W WO9640087A3 WO 1996040087 A3 WO1996040087 A3 WO 1996040087A3 US 9608492 W US9608492 W US 9608492W WO 9640087 A3 WO9640087 A3 WO 9640087A3
Authority
WO
WIPO (PCT)
Prior art keywords
pressure sensitive
linked
hydroxyl group
drug
sensitive acrylate
Prior art date
Application number
PCT/US1996/008492
Other languages
English (en)
Other versions
WO1996040087A2 (fr
Inventor
Chunhua Li
Edward Schonfeld
Tara Chu
Chia-Ming Chiang
Original Assignee
Cygnus Therapeutic Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cygnus Therapeutic Systems filed Critical Cygnus Therapeutic Systems
Priority to AU60326/96A priority Critical patent/AU6032696A/en
Publication of WO1996040087A2 publication Critical patent/WO1996040087A2/fr
Publication of WO1996040087A3 publication Critical patent/WO1996040087A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Abstract

L'invention se rapporte à une composition acrylique adhésive sensible à la pression, à base de solvant organique et sans effet de jaunissement, et qui présente de bonnes propriétés en matière de force de cohésion et d'écoulement à froid. Cette composition est utile dans la fabrication de timbres transdermiques pour l'administration des médicaments. Il s'agit d'une composition acrylique adhésive sensible à la pression à base de solvant organique, réticulée avec de l'acétylacétonate d'aluminium et combiné avec un médicament (par exemple estradiol) qui renferme un groupe hydroxyle aromatique réactif.
PCT/US1996/008492 1995-06-07 1996-06-03 Composition acrylique adhesive sensible a la pression reticulee avec de l'acetylacetonate d'aluminium et contenant un medicament qui renferme un groupe hydroxy aromatique reactif WO1996040087A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU60326/96A AU6032696A (en) 1995-06-07 1996-06-03 Pressure sensitive acrylate adhesive composition cross-linke d with aluminum acetylacetonate and containing a drug having a reactive aromatic hydroxyl group

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48429495A 1995-06-07 1995-06-07
US08/484,294 1995-06-07

Publications (2)

Publication Number Publication Date
WO1996040087A2 WO1996040087A2 (fr) 1996-12-19
WO1996040087A3 true WO1996040087A3 (fr) 1997-01-30

Family

ID=23923554

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/008492 WO1996040087A2 (fr) 1995-06-07 1996-06-03 Composition acrylique adhesive sensible a la pression reticulee avec de l'acetylacetonate d'aluminium et contenant un medicament qui renferme un groupe hydroxy aromatique reactif

Country Status (2)

Country Link
AU (1) AU6032696A (fr)
WO (1) WO1996040087A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9186335B2 (en) 2002-07-30 2015-11-17 Ucb Pharma Gmbh Hot melt TTS for administering rotigotine

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL181582B1 (pl) * 1995-06-07 2001-08-31 Ortho Mcneil Pharm Inc Plaster na skóre do zapobiegania owulacji u kobiety oraz plaster na skóre do przeprowadzania hormonalnej terapii substytucyjnej PL PL PL PL PL PL PL PL
DE19706824C1 (de) * 1997-02-21 1998-03-26 Lohmann Therapie Syst Lts Transdermales oder topisches Plastersystem mit Polyacrylatmatrix mit verbesserten physikalischen Eigenschaften
DE19814084B4 (de) 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE10000333A1 (de) * 2000-01-07 2001-07-19 Lohmann Therapie Syst Lts Pharmazeutische Zusammensetzung zur transdermalen Verabreichung von Hormonen mit einem permeationsverbessernden Zusatzstoff
DE60121965T2 (de) * 2000-06-01 2006-11-30 Kraton Polymers Research B.V. Funktionalisierte blockcopolymere enthaltende zusammensetzungen, die mit aluminiumacetylacetonaten vernetzt sind
DE10157745A1 (de) * 2001-11-24 2003-06-26 Hf Arzneimittelforsch Gmbh Transdermales therapeutisches System zur Verabreichung von 17alpha-Estradiol
US6653408B1 (en) 2002-11-21 2003-11-25 Kraton Polymers U.S. Llc Compositions comprising a functionalized block copolymer crosslinked with aluminum acetylacetonate
US7816546B2 (en) 2003-06-30 2010-10-19 Richter Gedeon Vegyeszeti Gyar Rt. Process for the synthesis of high purity d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-oxime
DE10333393A1 (de) * 2003-07-23 2005-02-24 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System mit dem Wirkstoff Pramipexol
ES2865139T3 (es) 2014-07-04 2021-10-15 Luye Pharma Ag Dispositivo para la fabricación de parches farmacéuticos
EP3474831A1 (fr) 2016-06-23 2019-05-01 Corium International, Inc. Matrice adhésive à un domaine hydrophile, un domaine hydrophobes et un agent thérapeutique
WO2018022814A1 (fr) 2016-07-27 2018-02-01 Corium International, Inc. Systèmes d'administration transdermique à pharmacocinétique bioéquivalent à l'administration orale
MX2019001104A (es) 2016-07-27 2019-10-02 Corium Int Inc Sistemas de suministro transdermico de memantina.
KR20230109782A (ko) 2016-07-27 2023-07-20 코리움, 엘엘씨 아민 약물의 나트륨 바이카보네이트 제자리 전환 구동된경피성 전달
US11173132B2 (en) 2017-12-20 2021-11-16 Corium, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0435200A2 (fr) * 1989-12-28 1991-07-03 Nitto Denko Corporation Composition de gel contenant des oestrogènes
US5204109A (en) * 1989-12-28 1993-04-20 Nitto Denko Corporation Percutaneous gel preparation
US5240711A (en) * 1989-11-29 1993-08-31 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system comprising as active component buprenorphine
US5298258A (en) * 1989-12-28 1994-03-29 Nitto Denko Corporation Acrylic oily gel bioadhesive material and acrylic oily gel preparation
US5306503A (en) * 1990-06-25 1994-04-26 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Patch with a high content of softening ingredients

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5240711A (en) * 1989-11-29 1993-08-31 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Transdermal therapeutic system comprising as active component buprenorphine
EP0435200A2 (fr) * 1989-12-28 1991-07-03 Nitto Denko Corporation Composition de gel contenant des oestrogènes
US5204109A (en) * 1989-12-28 1993-04-20 Nitto Denko Corporation Percutaneous gel preparation
US5298258A (en) * 1989-12-28 1994-03-29 Nitto Denko Corporation Acrylic oily gel bioadhesive material and acrylic oily gel preparation
US5306503A (en) * 1990-06-25 1994-04-26 Lts Lohmann Therapie-Systeme Gmbh & Co. Kg Patch with a high content of softening ingredients

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9186335B2 (en) 2002-07-30 2015-11-17 Ucb Pharma Gmbh Hot melt TTS for administering rotigotine

Also Published As

Publication number Publication date
AU6032696A (en) 1996-12-30
WO1996040087A2 (fr) 1996-12-19

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