WO1996037472A3 - Microbicides a base de pyridine - Google Patents

Microbicides a base de pyridine Download PDF

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Publication number
WO1996037472A3
WO1996037472A3 PCT/EP1996/002060 EP9602060W WO9637472A3 WO 1996037472 A3 WO1996037472 A3 WO 1996037472A3 EP 9602060 W EP9602060 W EP 9602060W WO 9637472 A3 WO9637472 A3 WO 9637472A3
Authority
WO
WIPO (PCT)
Prior art keywords
halogen
hydrogen
microbicides
pyridine
protecting
Prior art date
Application number
PCT/EP1996/002060
Other languages
English (en)
Other versions
WO1996037472A2 (fr
Inventor
Thomas Maetzke
Original Assignee
Ciba Geigy Ag
Thomas Maetzke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag, Thomas Maetzke filed Critical Ciba Geigy Ag
Priority to EP96916067A priority Critical patent/EP0828713A2/fr
Priority to JP8535336A priority patent/JPH11510788A/ja
Priority to AU58963/96A priority patent/AU5896396A/en
Publication of WO1996037472A2 publication Critical patent/WO1996037472A2/fr
Publication of WO1996037472A3 publication Critical patent/WO1996037472A3/fr

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/18Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/68One oxygen atom attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/83Thioacids; Thioesters; Thioamides; Thioimides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/86Hydrazides; Thio or imino analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention se rapporte à de nouveaux dérivés de pyridine substitués de la formule générale (I) dans laquelle X1 représente halogène ou hydrogène, X2 représente halogène; Z représente -C(=O)A, -C(=S)A ou -CH(OR2)2, et dans laquelle A représente hydrogène, OR3, SR3, NR4R5, NHOR6, -ON=CR7R8 ou NH-N(=C)n(R9)R10; R1 est tel que défini dans le descriptif. Les nouveaux composés actifs possèdent des propriétés protégeant les plantes et sont notamment appropriés pour protéger les plantes contre les infestations de micro-organismes phytopathogènes tels que les champignons, les bactéries et les virus.
PCT/EP1996/002060 1995-05-24 1996-05-14 Microbicides a base de pyridine WO1996037472A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP96916067A EP0828713A2 (fr) 1995-05-24 1996-05-14 Microbicides a base de pyridine
JP8535336A JPH11510788A (ja) 1995-05-24 1996-05-14 ピリジン殺菌剤
AU58963/96A AU5896396A (en) 1995-05-24 1996-05-14 Pyridine-microbicides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1546/95 1995-05-24
CH154695 1995-05-24

Publications (2)

Publication Number Publication Date
WO1996037472A2 WO1996037472A2 (fr) 1996-11-28
WO1996037472A3 true WO1996037472A3 (fr) 1997-01-09

Family

ID=4212949

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1996/002060 WO1996037472A2 (fr) 1995-05-24 1996-05-14 Microbicides a base de pyridine

Country Status (6)

Country Link
EP (1) EP0828713A2 (fr)
JP (1) JPH11510788A (fr)
AU (1) AU5896396A (fr)
IL (1) IL118380A0 (fr)
WO (1) WO1996037472A2 (fr)
ZA (1) ZA964127B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8895556B2 (en) 2007-12-26 2014-11-25 Critical Outcome Technologies Inc. Compounds and method for treatment of cancer
US8987272B2 (en) 2010-04-01 2015-03-24 Critical Outcome Technologies Inc. Compounds and method for treatment of HIV
US9284275B2 (en) 2007-01-11 2016-03-15 Critical Outcome Technologies Inc. Inhibitor compounds and cancer treatment methods

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999012907A1 (fr) 1997-09-10 1999-03-18 Dainippon Ink And Chemicals, Inc. Derives de 2,6-dichloro-4-pyridinemethanol et produits chimiques utilises en agriculture
US6133447A (en) * 1998-02-27 2000-10-17 Novartis Crop Protection, Inc. Process for the preparation of substituted pyridines
US6306839B1 (en) 1998-09-16 2001-10-23 Dow Agrosciences Llc 2-methoxyimino-2-(pyridinyloxymethyl) phenyl acetamides with (derivatised) hydroxyalkyl derivatives on the pyridine ring
PL206415B1 (pl) 1999-07-20 2010-08-31 Dow Agrosciences Llc Heterocykliczny amid aromatyczny, kompozycja grzybobójcza heterocyklicznego amidu aromatycznego oraz sposób zwalczania lub zapobiegania zakażeniom grzybami
US20020177578A1 (en) 1999-07-20 2002-11-28 Ricks Michael J. Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
US6355660B1 (en) 1999-07-20 2002-03-12 Dow Agrosciences Llc Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
EP1234827A3 (fr) * 1999-08-20 2003-06-18 Dow AgroSciences LLC Amides aromatiques, hétérocycliques fongicides et leurs compositions ainsi que mode d'emploi et préparation
CZ2002487A3 (cs) * 1999-08-20 2002-06-12 Dow Agrosciences Llc Fungicidní heterocyklické aromatické amidy, prostředky na jejich bázi, způsoby jejich pouľití a přípravy
KR100720766B1 (ko) * 1999-08-20 2007-05-22 다우 아그로사이언시즈 엘엘씨 살균성 헤테로사이클릭 방향족 아미드 및 그 조성물, 이용및 제조방법
CN102321016B (zh) * 2011-07-29 2013-04-10 山东轻工业学院 5-溴-2-羟基异烟酸甲酯的合成方法
ES2666144T3 (es) 2012-12-28 2018-05-03 Dow Agrosciences Llc Mezclas fungicidas sinérgicas para control fúngico en cereales
RU2703402C2 (ru) 2014-12-30 2019-10-16 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Пиколинамиды с фунгицидной активностью
RU2702697C2 (ru) 2014-12-30 2019-10-09 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Использование пиколинамидных соединений с фунгицидной активностью
WO2016109305A1 (fr) 2014-12-30 2016-07-07 Dow Agrosciences Llc Utilisation de picolinamides en tant que fongicides
CA2972405A1 (fr) 2014-12-30 2016-07-07 Dow Agrosciences Llc Utilisation de composes de picolinamide en tant que fongicides
AU2015374458B2 (en) 2014-12-30 2018-02-15 Dow Agrosciences Llc Use of picolinamide compounds with fungicidal activity
US10231452B2 (en) 2016-08-30 2019-03-19 Dow Agrosciences Llc Thiopicolinamide compounds with fungicidal activity
WO2018045003A1 (fr) 2016-08-30 2018-03-08 Dow Agrosciences Llc Composés de n-oxdes de picolinamide à activité fongicide
WO2018044996A1 (fr) 2016-08-30 2018-03-08 Dow Agrosciences Llc Picolinamides utilisés en tant que fongicides
US10334852B2 (en) 2016-08-30 2019-07-02 Dow Agrosciences Llc Pyrido-1,3-oxazine-2,4-dione compounds with fungicidal activity
BR102018000183B1 (pt) 2017-01-05 2023-04-25 Dow Agrosciences Llc Picolinamidas, composição para controle de um patógeno fúngico, e método para controle e prevenção de um ataque por fungos em uma planta
EP3618626A4 (fr) 2017-05-02 2020-12-02 Dow Agrosciences LLC Utilisation d'un composé picolinamide acyclique en tant que fongicide pour lutter contre des maladies fongiques sur des gazons
TW201842851A (zh) 2017-05-02 2018-12-16 美商陶氏農業科學公司 用於穀類中的真菌防治之協同性混合物
TWI774761B (zh) 2017-05-02 2022-08-21 美商科迪華農業科技有限責任公司 用於穀物中的真菌防治之協同性混合物
BR102019004480B1 (pt) 2018-03-08 2023-03-28 Dow Agrosciences Llc Picolinamidas como fungicidas
CA3115684A1 (fr) 2018-10-15 2020-04-23 Dow Agrosciences Llc Procedes de synthese d'oxypicolinamides
CN112028821A (zh) * 2020-09-26 2020-12-04 安徽金禾实业股份有限公司 一种2-甲基-3-甲氧基-4-氯吡啶的合成方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0268775A1 (fr) * 1986-09-26 1988-06-01 Ciba-Geigy Ag Méthode pour la protection des plantes contre des maladies
EP0288976A2 (fr) * 1987-04-29 1988-11-02 Ciba-Geigy Ag Agent protecteur contre les maladies de plantes
EP0332579A2 (fr) * 1988-03-09 1989-09-13 Ciba-Geigy Ag Méthode de protection de plantes contre des maladies
EP0334813A2 (fr) * 1988-03-25 1989-09-27 Ciba-Geigy Ag Agents pour la protection de plantes contre des maladies
JPH06228101A (ja) * 1993-01-29 1994-08-16 Ube Ind Ltd イソニコチン酸アミド誘導体、その製法及び農園芸用病害防除剤

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0268775A1 (fr) * 1986-09-26 1988-06-01 Ciba-Geigy Ag Méthode pour la protection des plantes contre des maladies
EP0288976A2 (fr) * 1987-04-29 1988-11-02 Ciba-Geigy Ag Agent protecteur contre les maladies de plantes
EP0332579A2 (fr) * 1988-03-09 1989-09-13 Ciba-Geigy Ag Méthode de protection de plantes contre des maladies
EP0334813A2 (fr) * 1988-03-25 1989-09-27 Ciba-Geigy Ag Agents pour la protection de plantes contre des maladies
JPH06228101A (ja) * 1993-01-29 1994-08-16 Ube Ind Ltd イソニコチン酸アミド誘導体、その製法及び農園芸用病害防除剤

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 18, no. 601 (C - 1274) 16 November 1994 (1994-11-16) *
REIFFENRATH ET AL, ANGEW. CHEMIE, vol. 106, no. 13, 1994, pages 1435 - 1438, XP002011124 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9284275B2 (en) 2007-01-11 2016-03-15 Critical Outcome Technologies Inc. Inhibitor compounds and cancer treatment methods
US8895556B2 (en) 2007-12-26 2014-11-25 Critical Outcome Technologies Inc. Compounds and method for treatment of cancer
US8987272B2 (en) 2010-04-01 2015-03-24 Critical Outcome Technologies Inc. Compounds and method for treatment of HIV
US9422282B2 (en) 2010-04-01 2016-08-23 Critical Outcome Technologies Inc. Compounds and method for treatment of HIV

Also Published As

Publication number Publication date
ZA964127B (en) 1996-11-25
EP0828713A2 (fr) 1998-03-18
IL118380A0 (en) 1996-09-12
AU5896396A (en) 1996-12-11
WO1996037472A2 (fr) 1996-11-28
JPH11510788A (ja) 1999-09-21

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