WO1996028150A1 - Therapeutic skin cream - Google Patents

Therapeutic skin cream Download PDF

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Publication number
WO1996028150A1
WO1996028150A1 PCT/NO1995/000038 NO9500038W WO9628150A1 WO 1996028150 A1 WO1996028150 A1 WO 1996028150A1 NO 9500038 W NO9500038 W NO 9500038W WO 9628150 A1 WO9628150 A1 WO 9628150A1
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WO
WIPO (PCT)
Prior art keywords
skin
fatty acids
oil
mixture
therapautic
Prior art date
Application number
PCT/NO1995/000038
Other languages
French (fr)
Inventor
Marit Eriksen
Original Assignee
Marit Eriksen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marit Eriksen filed Critical Marit Eriksen
Priority to PCT/NO1995/000038 priority Critical patent/WO1996028150A1/en
Publication of WO1996028150A1 publication Critical patent/WO1996028150A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/04Tars; Bitumens; Mineral oils; Ammonium bituminosulfonate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/925Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of animal origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/927Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/001Preparations for care of the lips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin

Definitions

  • the invention concerns a mixture of seal oil, beeswax, with tree tar and perfume eventually added, with a
  • therapautic effect on skin diseases as for example psoriasis, atopic exema, dry skin and broken lips.
  • Seal hunting has taken place for at least a thousand years.
  • the meat has been used for food, the skin for clothing and other useful things, and the blubber for different oil
  • Seal oil has had the same usage as whale oil. Among other things it has been used in lamps to create light, and also as a nutrition added to the food ordinary consumed by the
  • oil paint An other use of the oil has been as a base for paint, called oil paint.
  • the combination of fatty acids in seal oil is described in the following way: The type of fatty acid is written in parenthesis, the first number is the amount of carbonatoms, number after the colon is the amount of doble bindings in the fatty acid. The combination given in areal % concerns
  • Vitamin E 1,0 rag./g oil
  • the cream contains two main components, seal oil, described earlier in this application, and beeswax.
  • the second component is beeswax, which contains many different, and partly unidentified components.
  • the known components are ca. 70 % complicated fatty acids, 15 % organic acids, 12% carbohydrates and 1 % free alcohols. Beeswax is also rich in A-vitamins, with 4044 I.E. pr
  • the beeswax contains acid. This acid is free, and is made during the storing of the wax, by hydrolysis. The number of acid characterizes the quality of the bees wax. You can measure the number of acid by titration with g/KOH/g.
  • Number of saponification Gives a distinction for the size of the molecules in the fatty acids of the wax. Big number means smaller molecules, and is a quality demand fox beeswax.
  • the border is between 95 and 100.
  • esters Is made of acid and alcohol separated in water. Esters are therefore considered anhydric connections between acid and alcohol. Wax is a big ester. Beeswax consist of esters and valuable alcohols.The Ester number is therefore an expression for how much ester it is compared to alcohol. Beeswaxs today is well known for a certain antibiotic effect, and have among others turned out to be a positive help in the treatment of skin tuberculoses.
  • the cream can eventually also contain tree-tar.
  • the tar develops as persperation " from the tree-roots, during this slow burning. The exact mixture is dependent on factors as which kiln is being used, what sort of trees are being burnt, how slow/fast
  • the skin cream can be mixed with spesific flower oils which have aromatic scents, at the same time as these oils are used in the homeopatic medicine for different types of skin disease.
  • This specific cream is made by heating the beeswax to the melting point, at a temperature of 60 -65 degrees C. The rest of the components are then heated to a similar temperature, and mixed in with the wax.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Insects & Arthropods (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Animal Husbandry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A mixture of refined seal oil, beeswax, tree tar and/or aromatic flower oils, with a therapeutic effect on skin diseases, for external use on the skin.

Description

THERAPAUTIC SKIN CREAM
The invention concerns a mixture of seal oil, beeswax, with tree tar and perfume eventually added, with a
therapautic effect on skin diseases, as for example psoriasis, atopic exema, dry skin and broken lips.
Seal hunting has taken place for at least a thousand years. The meat has been used for food, the skin for clothing and other useful things, and the blubber for different oil
products.
Seal oil has had the same usage as whale oil. Among other things it has been used in lamps to create light, and also as a nutrition added to the food ordinary consumed by the
population. An other use of the oil has been as a base for paint, called oil paint.
The effect of the oil adjusted the human body has been known for many years. Seal- and whale oil has roughly the same structure as ordinary fish oil. Science has recently
discovered that the combination of fatty acids from seals and whales are somewhat better and more useful for the human body. This concerns the number and amount of s.k. monosaturatυd fatty acids.
The combination of fatty acids in seal oil is described in the following way: The type of fatty acid is written in parenthesis, the first number is the amount of carbonatoms, number after the colon is the amount of doble bindings in the fatty acid. The combination given in areal % concerns
the refined seal oil. All oil used in the product concerned is refined. Saturated fatty acids: 12,5 15, 1 (14:0, 16:0 18:0)
Monounsaturated fatty acids: 47,8 58,9 (14:1, 15:1, 18:1,
20:1, 22:1, 24:1)
Polyunsaturated fatty acids: 24,7 2,7 (18:2, 18:2, 18:4,
20:4, 20:5, 22:5, 22:6)
Vitamin E: 1,0 rag./g oil
Kolesterol: 1,3 mg./g oil
Seal oil has never earlier been used for medical purposes.
Lately there has been different scientific experiments around the medical effects of the seal oil. By now, there are very few scientific works to support that the seal oil has such effect. The science has so far mostly been done by The
Norwegian Institute of Fisheries and Aquaculture, and the University of Tromsø. Among other documentation we mention "Some possible effects of diatary monυsaturated fatty acids on cardiovascular disease" , by E. Elvevoll, O.Moen, R.L. Olsen and J. Brox, Atherosclerosis, 81(1990) p. 41 74, and
"alternative use of the seal oil", by Jenssen, final report publishes by NFFR 3001-2300.043.
The research and science has so far been directed to the effects of internal use of the oil.
The cream contains two main components, seal oil, described earlier in this application, and beeswax.
Added to these main components are mixtures of tar and aromatic oils
The second component is beeswax, which contains many different, and partly unidentified components.
The known components are ca. 70 % complicated fatty acids, 15 % organic acids, 12% carbohydrates and 1 % free alcohols. Beeswax is also rich in A-vitamins, with 4044 I.E. pr
100 kilograms.
The contents of beeswax is dependent on many variable factors, like where it is harvested, and time of year. The chart on the next page shows an analysis of beeswax from different times in the period of januar til july, and
is made by the Norwegian Honey Harvesters Organization during 1991.
Figure imgf000006_0001
In the last part of table 2 and 3 there are enshortenments for colour and smell characterized by the following
Y.Br.= Yellow-Brown, Honn. = Honey.
The parameters on the left side of the table is given a closer explanation underneath.
Number of acids: The beeswax contains acid. This acid is free, and is made during the storing of the wax, by hydrolysis. The number of acid characterizes the quality of the bees wax. You can measure the number of acid by titration with g/KOH/g.
It means by adding lye.
Number of saponification: Gives a distinction for the size of the molecules in the fatty acids of the wax. Big number means smaller molecules, and is a quality demand fox beeswax.
The border is between 95 and 100.
Number of esters: Is made of acid and alcohol separated in water. Esters are therefore considered anhydric connections between acid and alcohol. Wax is a big ester. Beeswax consist of esters and valuable alcohols.The Ester number is therefore an expression for how much ester it is compared to alcohol. Beeswaxs today is well known for a certain antibiotic effect, and have among others turned out to be a positive help in the treatment of skin tuberculoses.
The cream can eventually also contain tree-tar. This contains resin and different drug substances brough forward by burning the trees in a special way. The tar develops as persperation " from the tree-roots, during this slow burning. The exact mixture is dependent on factors as which kiln is being used, what sort of trees are being burnt, how slow/fast
the burning is done, and also what combination of trees which are used.
To achive a pleasant smell, the skin cream can be mixed with spesific flower oils which have aromatic scents, at the same time as these oils are used in the homeopatic medicine for different types of skin disease.
This specific cream is made by heating the beeswax to the melting point, at a temperature of 60 -65 degrees C. The rest of the components are then heated to a similar temperature, and mixed in with the wax.

Claims

PATENTCLAIMS
1. A therapautic mixture for external use on the skin,
c h a r a c t e r i z e d by containing (50-80)% seal oil, (0-7)% tree tar, (20-50)% beeswax an eventually one or several aromatic oils.
2. A therapautic mixture for external use on the skin, as mentioned in claim 1, c h a r a c t e r i z e d by the
beeswax, which among other contents 70 % complicated fatty acids, 19% inorganic acids 12 % carbohydrates and 1 % free alcohols.
3. A therapautic mixture for external use on the skin, as mentioned in claim 1, c h a r a c t e r i z e d by the seal oil, which contains (12,5- 15,4) saturated acids, (47,8-58,9)% momounsaturated fatty acids, (24,7 - 32,7)% polyunsaturated fatty acids, 1,0 mg/g oil vitamin E, and 1,3 mg/g oil
kolesterol.
4. A therapautic mixture for external use on the skin as mentioned in claim 1, c h a r a c t e r i z e d by the
contents of the saturated fatty acids of the seal oil mainly is the types 14:0, 16:0 and 18:0.
5. A therapautic mixture for external use on the skin as mentioned in claim 1, c h a r a c t e r i z e d by the monounsaturated fatty acids in the seal oil, whic mainly is of the types 14:1, 16:1, 18:1, 20:1, 22:1, 24:1.
6. A therapautic mixture for external use on the skin as mentioned in claim 1, c h a r a c t e r i z e d by the polyunsaturated fatty acids in the seal oil mainly is of the types 18:2, 18:3, 18:4, 20:4, 20:5 22:5, 22:6.
PCT/NO1995/000038 1995-02-20 1995-02-20 Therapeutic skin cream WO1996028150A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/NO1995/000038 WO1996028150A1 (en) 1995-02-20 1995-02-20 Therapeutic skin cream

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/NO1995/000038 WO1996028150A1 (en) 1995-02-20 1995-02-20 Therapeutic skin cream

Publications (1)

Publication Number Publication Date
WO1996028150A1 true WO1996028150A1 (en) 1996-09-19

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000044862A1 (en) * 1999-01-29 2000-08-03 Atlantis Marine Inc. Process of converting rendered triglyceride oil from marine sources into bland, stable oil
WO2002013838A1 (en) * 2000-08-16 2002-02-21 Fundaçao Essprit-Icarus (Fundaçao Europeia De Investigaçao Medica), Ngo; Ipss. Seal-oil-based pharmaceutical, cosmetic, dermo-cosmetic, hygiene, alimentary and para-alimentary (food-supplements) products; their methods of preparation; their uses as preventive and/or as therapeutic agents
WO2003047596A2 (en) * 2001-12-06 2003-06-12 Margaret Bronnert Ointment for soothing dermatitis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4022815A1 (en) * 1990-07-18 1992-01-23 Braun Melsungen Ag Topical preparation contg. omega-3-fatty acids - for prophylaxis and treatment of skin inflammation e.g. eczema, burns, acene, contact allergies etc.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4022815A1 (en) * 1990-07-18 1992-01-23 Braun Melsungen Ag Topical preparation contg. omega-3-fatty acids - for prophylaxis and treatment of skin inflammation e.g. eczema, burns, acene, contact allergies etc.

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, Volume 110, No. 3, 16 January 1989, (Columbus, Ohio, USA), RATNAYAKE W.M.N. et al., "Preparation of Omega-3 PUFA Concentrates from Fish Oils Via Urea Complexation", Abstract No. 22481z; & FETT WISS. TECHNOL., 1988, 90(10), 381-386. *
CHEMICAL ABSTRACTS, Volume 122, No. 3, 16 January 1995, (Columbus, Ohio, USA), CHRISTENSEN, MICHAEL SOBERG et al., "Lymphatic Absorption of N-3 Polyunsaturated Fatty Acids from Marine Oils with Different Intramolecular Fatty Acid Distributions", Abstract No. 30475p; & BIOCHIM. BIOPHYS. ACTA, 1994, 1215(1/2), 198-204. *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000044862A1 (en) * 1999-01-29 2000-08-03 Atlantis Marine Inc. Process of converting rendered triglyceride oil from marine sources into bland, stable oil
US7179491B1 (en) 1999-01-29 2007-02-20 Ted Mag Process of converting rendered triglyceride oil from marine sources into bland, stable oil
WO2002013838A1 (en) * 2000-08-16 2002-02-21 Fundaçao Essprit-Icarus (Fundaçao Europeia De Investigaçao Medica), Ngo; Ipss. Seal-oil-based pharmaceutical, cosmetic, dermo-cosmetic, hygiene, alimentary and para-alimentary (food-supplements) products; their methods of preparation; their uses as preventive and/or as therapeutic agents
WO2003047596A2 (en) * 2001-12-06 2003-06-12 Margaret Bronnert Ointment for soothing dermatitis
FR2833174A1 (en) * 2001-12-06 2003-06-13 Margaret Bronnert FAT OINTMENT OF ANIMAL ORIGIN INTENDED TO RELIEVE SKIN IRRITATIONS AND IRRITATIONS DUE TO DERMITES, ATOPIC ECZEMA AND PSORIASIS, SKIN DROUGHT AND HYPERKERATINOSIS
WO2003047596A3 (en) * 2001-12-06 2004-01-22 Margaret Bronnert Ointment for soothing dermatitis

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