WO1996022774A3 - Combinational drugs for treating migraine and other illnesses, comprising sesquiterpene lactones and b-complex vitamins - Google Patents

Combinational drugs for treating migraine and other illnesses, comprising sesquiterpene lactones and b-complex vitamins Download PDF

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Publication number
WO1996022774A3
WO1996022774A3 PCT/CA1996/000052 CA9600052W WO9622774A3 WO 1996022774 A3 WO1996022774 A3 WO 1996022774A3 CA 9600052 W CA9600052 W CA 9600052W WO 9622774 A3 WO9622774 A3 WO 9622774A3
Authority
WO
WIPO (PCT)
Prior art keywords
illnesses
complex vitamins
treating migraine
sesquiterpene lactones
combinational drugs
Prior art date
Application number
PCT/CA1996/000052
Other languages
French (fr)
Other versions
WO1996022774A2 (en
Inventor
Natalie J Lazarowych
Peter Pekos
Michael O'connell
Original Assignee
Ashbury Research Corp
Natalie J Lazarowych
Peter Pekos
Oconnell Michael
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ashbury Research Corp, Natalie J Lazarowych, Peter Pekos, Oconnell Michael filed Critical Ashbury Research Corp
Priority to AU44780/96A priority Critical patent/AU4478096A/en
Priority to EP96900799A priority patent/EP0805680A2/en
Priority to JP8522519A priority patent/JPH10512573A/en
Publication of WO1996022774A2 publication Critical patent/WO1996022774A2/en
Publication of WO1996022774A3 publication Critical patent/WO1996022774A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

A preparation for pharmaceutical use, especially in the treatment of migraine, cluster headaches, arthritis and bronchial complaints, comprises a sesquiterpene lactone such as parthenolide and B-complex vitamins such as riboflavin (vitamin B2), as well as a method of treating and providing prophylaxis against such illnesses by use of such a combination.
PCT/CA1996/000052 1995-01-26 1996-01-25 Combinational drugs for treating migraine and other illnesses, comprising sesquiterpene lactones and b-complex vitamins WO1996022774A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU44780/96A AU4478096A (en) 1995-01-26 1996-01-25 Combinational drugs for treating migraine and other illnesses, comprising sesquiterpene lactones and b-complex vitamins
EP96900799A EP0805680A2 (en) 1995-01-26 1996-01-25 Combinational drugs for treating migraine and other illnesses, comprising sesquiterpene lactones and b-complex vitamins
JP8522519A JPH10512573A (en) 1995-01-26 1996-01-25 Combination agent for treating migraine and other diseases, comprising sesquiterpene lactone and vitamin B complex

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA2,141,126 1995-01-26
CA002141126A CA2141126A1 (en) 1995-01-26 1995-01-26 Combinational drug for treating migraine and other illnesses

Publications (2)

Publication Number Publication Date
WO1996022774A2 WO1996022774A2 (en) 1996-08-01
WO1996022774A3 true WO1996022774A3 (en) 1996-09-26

Family

ID=4155120

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA1996/000052 WO1996022774A2 (en) 1995-01-26 1996-01-25 Combinational drugs for treating migraine and other illnesses, comprising sesquiterpene lactones and b-complex vitamins

Country Status (6)

Country Link
EP (1) EP0805680A2 (en)
JP (1) JPH10512573A (en)
KR (1) KR19980701720A (en)
AU (1) AU4478096A (en)
CA (1) CA2141126A1 (en)
WO (1) WO1996022774A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2283122A1 (en) * 1997-03-03 1998-09-11 Laboratoires Remilea Plant extract compositions, method of preparation, and pharmaceutical compositions containing them
US6365180B1 (en) * 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
US6068999A (en) 1998-06-25 2000-05-30 Hendrix; Curt Dietary supplement for supporting cerebrovascular tone and treating migraine headaches
DE19844836A1 (en) * 1998-09-30 2000-04-20 Hexal Ag Pharmaceutical, effective, herbal preparation for the treatment of migraines
DE69904257T2 (en) 1999-01-20 2003-04-17 N.V. Nutricia, Zoetermeer infant formula
US6312736B1 (en) * 1999-12-09 2001-11-06 Biotech Corporation Herbal composition to relieve pain
US6890946B2 (en) 1999-12-23 2005-05-10 Indiana University Research And Technology Corporation Use of parthenolide to inhibit cancer
CA2406733A1 (en) * 1999-12-23 2001-06-28 Harikrishna Nakshatri Use of parthenolide to inhibit cancer
US7192614B2 (en) * 2002-11-05 2007-03-20 Gelstat Corporation Compositions and methods of treatment to alleviate or prevent migrainous headaches and their associated symptoms
US20040247705A1 (en) * 2003-06-06 2004-12-09 Roberts Stephen C. Transdermal compositions and methods of treatment to alleviate or prevent migrainous headaches and their associated symptoms
WO2008010335A1 (en) * 2006-07-21 2008-01-24 Mmt Co., Ltd. Plant extract having arthritis-preventive effect
WO2008075649A1 (en) * 2006-12-20 2008-06-26 Mmt Co., Ltd. Food or drink, quasi drug and medicinal composition for promoting hair growth and method of promoting hair growth
WO2008075466A1 (en) * 2006-12-20 2008-06-26 Mmt Co., Ltd. Food and drink, quasi drug and pharmaceutical composition for promoting hair growth, and method for promoting hair growth
CN101278928B (en) 2007-04-06 2011-09-07 常州高新技术产业开发区三维工业技术研究所有限公司 Medicament composition containing levocarnitine or its derivatives and use thereof
US20100284986A1 (en) * 2009-05-06 2010-11-11 Kelleher Kevin J Compositions and methods for prevention and treatment of migraines
IT201700085185A1 (en) * 2017-07-26 2019-01-26 Cristalfarma S R L Food supplement for use as an adjunct in the treatment and prophylaxis of migraine

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR4173M (en) * 1965-02-01 1966-05-23
EP0098041A2 (en) * 1982-05-19 1984-01-11 R.P. Scherer Corporation Sesquiterpene lactones, extracts containing them, their preparation and pharmaceutical use
US4542026A (en) * 1983-04-29 1985-09-17 Jose Rios Method of treating vasomotor disorders
EP0293790A1 (en) * 1987-06-05 1988-12-07 Nikko Sogyo Yugen Kaisha A composition for preventing loss of hair and facilitating growth of hair
DE3808141A1 (en) * 1988-03-11 1989-09-21 Mai Jutta Composition for controlling migraine
EP0525740A1 (en) * 1991-08-01 1993-02-03 Dozono, Fumio Stevia extract-containing liquid internal medicine and method of preparing the same
JPH05306231A (en) * 1992-04-24 1993-11-19 Pola Chem Ind Inc Skin external preparation
WO1994001899A1 (en) * 1992-07-02 1994-01-20 W. L. Gore & Associates, Inc. Sealing frame and protective membrane for a radar dish or horn

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR4173M (en) * 1965-02-01 1966-05-23
EP0098041A2 (en) * 1982-05-19 1984-01-11 R.P. Scherer Corporation Sesquiterpene lactones, extracts containing them, their preparation and pharmaceutical use
US4542026A (en) * 1983-04-29 1985-09-17 Jose Rios Method of treating vasomotor disorders
EP0293790A1 (en) * 1987-06-05 1988-12-07 Nikko Sogyo Yugen Kaisha A composition for preventing loss of hair and facilitating growth of hair
DE3808141A1 (en) * 1988-03-11 1989-09-21 Mai Jutta Composition for controlling migraine
EP0525740A1 (en) * 1991-08-01 1993-02-03 Dozono, Fumio Stevia extract-containing liquid internal medicine and method of preparing the same
JPH05306231A (en) * 1992-04-24 1993-11-19 Pola Chem Ind Inc Skin external preparation
WO1994001899A1 (en) * 1992-07-02 1994-01-20 W. L. Gore & Associates, Inc. Sealing frame and protective membrane for a radar dish or horn

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 9351, Derwent World Patents Index; AN 93-408845 *
PATENT ABSTRACTS OF JAPAN vol. 018, no. 114 (C - 1171) 24 February 1994 (1994-02-24) *

Also Published As

Publication number Publication date
WO1996022774A2 (en) 1996-08-01
JPH10512573A (en) 1998-12-02
CA2141126A1 (en) 1996-07-27
KR19980701720A (en) 1998-06-25
EP0805680A2 (en) 1997-11-12
AU4478096A (en) 1996-08-14

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