WO1996022110A3 - Pharmaceutical products containing thermally-inhibited starches - Google Patents

Pharmaceutical products containing thermally-inhibited starches Download PDF

Info

Publication number
WO1996022110A3
WO1996022110A3 PCT/US1996/000612 US9600612W WO9622110A3 WO 1996022110 A3 WO1996022110 A3 WO 1996022110A3 US 9600612 W US9600612 W US 9600612W WO 9622110 A3 WO9622110 A3 WO 9622110A3
Authority
WO
WIPO (PCT)
Prior art keywords
flour
starch
pharmaceutical products
anhydrous
starches
Prior art date
Application number
PCT/US1996/000612
Other languages
French (fr)
Other versions
WO1996022110A2 (en
Inventor
James J Kasica
David J Thomas
James P Zallie
Original Assignee
Nat Starch Chem Invest
James J Kasica
David J Thomas
James P Zallie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Starch Chem Invest, James J Kasica, David J Thomas, James P Zallie filed Critical Nat Starch Chem Invest
Priority to AU47009/96A priority Critical patent/AU4700996A/en
Priority to EP96902701A priority patent/EP0804243A2/en
Priority to US08/595,008 priority patent/US5830884A/en
Publication of WO1996022110A2 publication Critical patent/WO1996022110A2/en
Publication of WO1996022110A3 publication Critical patent/WO1996022110A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
    • C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch

Abstract

Thermally-inhibited starches and flours are used in pharmaceutical products as a diluent, filler, carrier, binder, disintegrant, coating, thickener, moisture sink, and the like. The starches and flours are inhibited by dehydrating the starch or flour to substantially anhydrous or anhydrous and then heat treating the anhydrous or substantially anhydrous starch or flour for a time and at a temperature sufficient to inhibit the starch or flour. The dehydration can be carried out by heating the starch or flour, by extracting the starch or flour with a solvent, or by freeze-drying. Preferably, the pH is adjusted to a neutral pH or above prior to the dehydration and heat treatment.
PCT/US1996/000612 1995-01-18 1996-01-17 Pharmaceutical products containing thermally-inhibited starches WO1996022110A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU47009/96A AU4700996A (en) 1995-01-18 1996-01-17 Pharmaceutical products containing thermally-inhibited starches
EP96902701A EP0804243A2 (en) 1995-01-18 1996-01-17 Pharmaceutical products containing thermally-inhibited starches
US08/595,008 US5830884A (en) 1995-01-18 1996-01-31 Pharmaceutical products containing thermally-inhibited starches

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37532195A 1995-01-18 1995-01-18
US08/375,321 1995-01-18

Publications (2)

Publication Number Publication Date
WO1996022110A2 WO1996022110A2 (en) 1996-07-25
WO1996022110A3 true WO1996022110A3 (en) 1996-12-12

Family

ID=23480419

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/000612 WO1996022110A2 (en) 1995-01-18 1996-01-17 Pharmaceutical products containing thermally-inhibited starches

Country Status (3)

Country Link
EP (1) EP0804243A2 (en)
AU (1) AU4700996A (en)
WO (1) WO1996022110A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013299A (en) 1997-11-04 2000-01-11 Nabisco Techology Company Process for making enzyme-resistant starch for reduced-calorie flour replacer
FR2779439B1 (en) * 1998-06-08 2000-08-25 Roquette Freres DILUENT AND DISINTEGRANT COMPOSITION, PROCESS FOR OBTAINING SAME AND USE THEREOF
US6846497B2 (en) * 2003-01-30 2005-01-25 National Starch And Chemical Investment Holding Corporation Rapidly expanding starches with altered crystalline structure
US8431618B2 (en) 2008-03-31 2013-04-30 Asahi Kasei Chemicals Corporation Processed starch powder with excellent disintegration properties and manufacturing method thereof
WO2024006914A1 (en) * 2022-06-30 2024-01-04 Cargill, Incorporated Process for preparing a thermally inhibited bleached starch

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB595552A (en) * 1943-12-13 1947-12-09 Corn Prod Refining Co Improvements in or relating to processes of treating starch to render it substantially free of thermophilic bacteria
US3977897A (en) * 1975-09-08 1976-08-31 National Starch And Chemical Corporation Process for preparing a non-chemically inhibited starch
US4391836A (en) * 1980-08-08 1983-07-05 National Starch And Chemical Corporation Process for preparing instant gelling starches
JPS61254602A (en) * 1985-05-08 1986-11-12 Nichiden Kagaku Kk Production of modified starch
WO1995004082A2 (en) * 1993-07-30 1995-02-09 National Starch And Chemical Investment Holding Corporation Heat treated noncohesive starches and flours and process for their production

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB595552A (en) * 1943-12-13 1947-12-09 Corn Prod Refining Co Improvements in or relating to processes of treating starch to render it substantially free of thermophilic bacteria
US3977897A (en) * 1975-09-08 1976-08-31 National Starch And Chemical Corporation Process for preparing a non-chemically inhibited starch
US4391836A (en) * 1980-08-08 1983-07-05 National Starch And Chemical Corporation Process for preparing instant gelling starches
JPS61254602A (en) * 1985-05-08 1986-11-12 Nichiden Kagaku Kk Production of modified starch
WO1995004082A2 (en) * 1993-07-30 1995-02-09 National Starch And Chemical Investment Holding Corporation Heat treated noncohesive starches and flours and process for their production

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
"Handbook of Pharmaceutical Excipients", 1986, AMERICAN PHARMACEUTICAL ASSOCIATION, WASHINGTON, XP002009779 *
"Ullmanns Encyclopädie der technischen Chemie, Vol. 22", 1982, VERLAG CHEMIE, WEINHEIM, XP002009780 *
DATABASE WPI Section Ch Week 8652, Derwent World Patents Index; Class B07, AN 86-341929, XP002009781 *
P.H LIST ET AL.: "Hagers Handbuch der Pharmazeutischen Praxis", 1977, SPRINGER VERLAG, BERLIN, XP002009778 *

Also Published As

Publication number Publication date
AU4700996A (en) 1996-08-07
WO1996022110A2 (en) 1996-07-25
EP0804243A2 (en) 1997-11-05

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