WO1996015222A1 - HUMAN MutT2 - Google Patents

HUMAN MutT2 Download PDF

Info

Publication number
WO1996015222A1
WO1996015222A1 PCT/US1994/013187 US9413187W WO9615222A1 WO 1996015222 A1 WO1996015222 A1 WO 1996015222A1 US 9413187 W US9413187 W US 9413187W WO 9615222 A1 WO9615222 A1 WO 9615222A1
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
hmutt2
dna
polynucleotide
sequence
Prior art date
Application number
PCT/US1994/013187
Other languages
English (en)
French (fr)
Inventor
Ying-Fei Wei
Ewen F. Kirkness
Original Assignee
Human Genome Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences, Inc. filed Critical Human Genome Sciences, Inc.
Priority to AU12558/95A priority Critical patent/AU1255895A/en
Priority to JP8516005A priority patent/JPH10509320A/ja
Priority to PCT/US1994/013187 priority patent/WO1996015222A1/en
Priority to EP95903538A priority patent/EP0795006A4/de
Publication of WO1996015222A1 publication Critical patent/WO1996015222A1/en
Priority to US08/916,989 priority patent/US6103871A/en
Priority to US09/432,253 priority patent/US6344547B1/en
Priority to US09/974,800 priority patent/US6552174B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
PCT/US1994/013187 1994-11-15 1994-11-15 HUMAN MutT2 WO1996015222A1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AU12558/95A AU1255895A (en) 1994-11-15 1994-11-15 Human mutt2
JP8516005A JPH10509320A (ja) 1994-11-15 1994-11-15 ヒトＭｕｔＴ２
PCT/US1994/013187 WO1996015222A1 (en) 1994-11-15 1994-11-15 HUMAN MutT2
EP95903538A EP0795006A4 (de) 1994-11-15 1994-11-15 MENSCHLICHES MuT2
US08/916,989 US6103871A (en) 1994-11-15 1997-08-21 Human mutT2
US09/432,253 US6344547B1 (en) 1994-11-15 1999-11-02 Human MutT2
US09/974,800 US6552174B2 (en) 1994-11-15 2001-10-12 Human MutT2 antibodies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1994/013187 WO1996015222A1 (en) 1994-11-15 1994-11-15 HUMAN MutT2

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US08/470,261 Continuation-In-Part US5695980A (en) 1994-11-15 1995-06-06 Polynucleotides, vectors, cells and an expression method for human MutT2

Publications (1)

Publication Number Publication Date
WO1996015222A1 true WO1996015222A1 (en) 1996-05-23

Family

ID=22243281

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/013187 WO1996015222A1 (en) 1994-11-15 1994-11-15 HUMAN MutT2

Country Status (4)

Country Link
EP (1) EP0795006A4 (de)
JP (1) JPH10509320A (de)
AU (1) AU1255895A (de)
WO (1) WO1996015222A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000065056A2 (en) * 1999-04-26 2000-11-02 Beth Israel Deaconess Medical Center, Inc. NUCLEIC ACIDS ENCODING A MutT DOMAIN-CONTAINING POLYPEPTIDE

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF BIOLOGICAL CHEMISTRY, Volume 268, No. 31, issued 05 November 1993, K. SAKUMI et al., "Cloning and Expression of a cDNA for a Human Enzyme that Hydrolyzes 8-Oxo-dGTP, a Mutagenic Substrate for DNA Synthesis", pages 23524-23530. *
MOLECULAR AND GENERAL GENETICS, Volume 206, issued 1987, M. AKIYAMA et al., "Molecular Cloning and Nucleotide Sequence of the MutT Mutator of Escherichia Coli that Causes A:T to C:G Transversion", pages 9-16. *
MUTATION RESEARCH, Volume 299, issued 1993, J. TCHOU et al., "Repair of DNA Containing the Oxidatively-Damagea Base, 8-Oxoguanine", pages 277-287. *
NATURE, Volume 355, issued 16 January 1992, H. MAKI et al., "MutT Protein Specifically Hydrolyses a Potent Mutagenic Substrate for DNA Synthesis", pages 273-275. *
PROC. NATL. ACAD. SCI. U.S.A., Volume 89, issued November 1992, J. MO et al., "Hydrolytic Elimination of a Mutagenic Nucleotide, 8-OxodGTP, by Human 18-Kilodalton Protein: Sanitization of Nucleotide Pool", pages 11021-11025. *
See also references of EP0795006A4 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000065056A2 (en) * 1999-04-26 2000-11-02 Beth Israel Deaconess Medical Center, Inc. NUCLEIC ACIDS ENCODING A MutT DOMAIN-CONTAINING POLYPEPTIDE
WO2000065056A3 (en) * 1999-04-26 2001-03-01 Beth Israel Hospital NUCLEIC ACIDS ENCODING A mutT DOMAIN-CONTAINING POLYPEPTIDE
US8153400B1 (en) 1999-04-26 2012-04-10 Beth Israel Deaconess Medical Center, Inc. Nucleic acids encoding a mutT domain-containing polypeptide
US8614300B2 (en) 1999-04-26 2013-12-24 Beth Israel Deconess Medical Center, Inc. Nucleic acids encoding a mut-T domain-containing polypeptide

Also Published As

Publication number Publication date
EP0795006A1 (de) 1997-09-17
AU1255895A (en) 1996-06-06
JPH10509320A (ja) 1998-09-14
EP0795006A4 (de) 1999-10-27

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