WO1996008270A3 - Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds - Google Patents

Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds Download PDF

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Publication number
WO1996008270A3
WO1996008270A3 PCT/US1995/011675 US9511675W WO9608270A3 WO 1996008270 A3 WO1996008270 A3 WO 1996008270A3 US 9511675 W US9511675 W US 9511675W WO 9608270 A3 WO9608270 A3 WO 9608270A3
Authority
WO
WIPO (PCT)
Prior art keywords
sexually transmitted
antimicrobials
magaining
transmitted diseases
squalamine
Prior art date
Application number
PCT/US1995/011675
Other languages
French (fr)
Other versions
WO1996008270A2 (en
WO1996008270A9 (en
Inventor
Leonard Jacob
Michael Zasloff
Taffy Williams
Gurrinder Bedi
Original Assignee
Magainin Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Magainin Pharma filed Critical Magainin Pharma
Priority to AU35125/95A priority Critical patent/AU3512595A/en
Publication of WO1996008270A2 publication Critical patent/WO1996008270A2/en
Publication of WO1996008270A3 publication Critical patent/WO1996008270A3/en
Publication of WO1996008270A9 publication Critical patent/WO1996008270A9/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Transmission of sexually transmitted disease is inhibited in humans by a method that comprises administering to a human one or more magainin antimicrobials or one or more squalamine compounds in an amount sufficient to inhibit transmission of sexually transmitted disease.
PCT/US1995/011675 1994-09-13 1995-09-13 Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds WO1996008270A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU35125/95A AU3512595A (en) 1994-09-13 1995-09-13 Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30547594A 1994-09-13 1994-09-13
US08/305,475 1994-09-13

Publications (3)

Publication Number Publication Date
WO1996008270A2 WO1996008270A2 (en) 1996-03-21
WO1996008270A3 true WO1996008270A3 (en) 1996-05-17
WO1996008270A9 WO1996008270A9 (en) 1996-06-27

Family

ID=23180966

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/011675 WO1996008270A2 (en) 1994-09-13 1995-09-13 Method for inhibiting sexually transmitted diseases using magaining antimicrobials or squalamine compounds

Country Status (2)

Country Link
AU (1) AU3512595A (en)
WO (1) WO1996008270A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856535A (en) * 1994-08-18 1999-01-05 Magainin Pharmaceuticals, Inc. Aminosterol ester compounds
FR2744453B1 (en) * 1996-02-05 1998-07-10 Transgene Sa LIPOPOLYAMINE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, NUCLEIC ACID TRANSFER VECTORS AND PREPARATION METHOD
US7410959B1 (en) 2000-07-13 2008-08-12 Genaera Corporation Therapeutic uses for aminosterol compounds
AU2911197A (en) * 1996-05-24 1998-01-05 Imperial College Of Science, Technology And Medicine Polycationic sterol derivatives as transfection agents
US6133233A (en) * 1997-02-18 2000-10-17 Kansas State University Research Foundation Peptide modulation of reperfusion injury
NL1008139C2 (en) * 1998-01-27 1999-07-28 Stichting Tech Wetenschapp Antimicrobial peptides.
US6767904B2 (en) 1998-03-06 2004-07-27 Bringham Young University Steroid derived antibiotics
NL1010692C2 (en) * 1998-12-01 2000-06-06 Stichting Tech Wetenschapp Antiviral peptides.
CN102145005A (en) * 2006-02-01 2011-08-10 杨百翰大学 Cationic steroid antimicrobial compositions and methods of use
WO2007089906A2 (en) * 2006-02-01 2007-08-09 Brigham Young University Cationic steroid antimicrobial compositions for treating or preventing herpes infections
WO2008048340A2 (en) 2006-02-01 2008-04-24 Brigham Young University Cationic steroid antimicrobial compositions for treating poxvirus infections
JP2007314432A (en) * 2006-05-23 2007-12-06 Japan Science & Technology Agency New antimicrobial peptide and serum-free medium containing the antimicrobial peptide as active ingredient
US8729058B2 (en) * 2009-10-27 2014-05-20 Michael Zasloff Methods and compositions for treating and preventing viral infections
WO2011066260A2 (en) 2009-11-25 2011-06-03 Michael Zasloff Formulations comprising aminosterols
US10040817B2 (en) 2013-10-03 2018-08-07 Enterin Laboratories, Inc. Methods and compositions for stimulation of the intestinal enteroendocrine system for treating diseases or conditions related to the same
EP3678671A4 (en) 2017-09-08 2022-12-07 Enterin, Inc. Methods for treating sleep disorders, sleep disturbances, and related symptoms using aminosterol compositions
WO2019234189A1 (en) * 2018-06-06 2019-12-12 Centro Nacional De Investigaciones Cardiovasculares Carlos Iii (F.S.P.) Enhanced trained immunity in myeloid cells by ship-1 inhibition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006597A1 (en) * 1987-03-04 1988-09-07 The United States Of America, As Represented By Th New synthetic bioactive compounds and method of producing bioactive effect
WO1993005802A1 (en) * 1991-09-13 1993-04-01 Magainin Pharmaceuticals Inc. Biologically active amphiphilic peptide compositions and uses therefor
WO1993024138A1 (en) * 1992-06-01 1993-12-09 Magainin Pharmaceuticals, Inc. Biologically active peptides having n-terminal substitutions
WO1994005313A1 (en) * 1992-08-31 1994-03-17 Magainin Pharmaceuticals Inc. Treatment of gynecological malignancies with biologically active peptides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8104929A (en) * 1980-11-12 1982-06-01 Alza Corp ANTICHOLINERGIC PREPARATIONS, PREPARATION AND USE THEREOF.
US4832953A (en) * 1987-08-13 1989-05-23 Alza Corporation Method for preventing the formation of a crystalline hydrate in a dispersion of a liquid in a monaqueous matrix
ATE101511T1 (en) * 1988-08-02 1994-03-15 Ciba Geigy Ag MULTI-LAYER PLASTER.
DE3908431A1 (en) * 1989-03-15 1990-09-27 Lohmann Therapie Syst Lts TRANSDERMAL SYSTEM WITH STAGE SUBSTANCE DELIVERY AND USE FOR LOCAL OR SYSTEMIC DISPENSER
JPH04261119A (en) * 1991-02-13 1992-09-17 Lintec Corp Percutaneous absorption-type pharmaceutical preparation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006597A1 (en) * 1987-03-04 1988-09-07 The United States Of America, As Represented By Th New synthetic bioactive compounds and method of producing bioactive effect
WO1993005802A1 (en) * 1991-09-13 1993-04-01 Magainin Pharmaceuticals Inc. Biologically active amphiphilic peptide compositions and uses therefor
WO1993024138A1 (en) * 1992-06-01 1993-12-09 Magainin Pharmaceuticals, Inc. Biologically active peptides having n-terminal substitutions
WO1994005313A1 (en) * 1992-08-31 1994-03-17 Magainin Pharmaceuticals Inc. Treatment of gynecological malignancies with biologically active peptides

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ABOUDY, Y. ET AL: "Activity of two synthetic amphiphilic peptides and magainin -2 against herpes simplex virus types 1 and 2", INT. J. PEPT. PROTEIN RES. (1994), 43(6), 573-82 *
CUERVO, JULIO H. ET AL: "The magainins: sequence factors relevant to increased antimicrobial activity and decreased hemolytic activity", PEPT. RES. (1988), 1(2), 81-6 *

Also Published As

Publication number Publication date
WO1996008270A2 (en) 1996-03-21
AU3512595A (en) 1996-03-29

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